Artificial dataset generation to enhance the design exploration of residential buildings through data-informed energy load forecasting models

This study aims to assist urban planners and building designers in taking informed decisions based on energy performance – simulating a real-world urban development scenario – using limited computational resources. In particular, this paper proposes a new approach that integrates existing studies on building loads forecasting by using a Generative Adversarial Network (GAN) generated dataset based on significant geometrical parameters. This overcomes the needs for large datasets – often difficult to access.The results demonstrate that the data-driven approaches have addressed the buildings' load predictions with a reasonable accuracy while significantly reducing the calculation time required

Intense terahertz pulses from SPARC-LAB coherent radiation source

The linac-based Terahertz source at the SPARC_LAB test facility is able to gene rate highly intense Terahertz broadband pulses via coherent transition radiation (CTR) from high brightness electron beams. The THz pulse duration is typically down to 100 fs RMS and can be tuned through the electron bunch duration and shaping. The measured stored energy in a single THz pulse has reached 40 μ J, which corresponds to a peak electric field of 1.6 MV/cm at the THz focus. Here we present the main features, in particular spatial and sp ectral distributions and energy characterizations of the SPARC_LAB THz source, which is very competitive for investigations in Condensed Matter, as well as a valid tool for electron beam longitudinal diagnostics

Insufficient knowledge among psoriasis patients can represent a barrier to participation in decision-making.

Patient participation in treatment decisions can have positive effects on patient satisfaction, compliance and health outcomes. The objectives of this study were to examine attitudes of psoriasis patients regarding participation in treatment decisions and to evaluate the effect of a decision-aid for discussing treatment options. A "quasi experiment" was conducted in a large dermatological hospital in Italy: a questionnaire evaluating the decision-making process and treatment knowledge was self-completed by 231 consecutive psoriasis patients after routine clinical practice and by a second sample of 171 patients exposed to a decision-board. In routine clinical practice 67.9% of patients wanted to be involved in decision-making, 28.4% wanted to leave decisions entirely to the doctor and 3.7% preferred making decisions alone. 17.9% and 25.3% of the control and decision-board group had good knowledge. At multivariate analysis good knowledge increased the likelihood of preferring an active role (risk ratio (RR) = 2.21; 95% confidence interval (CI) 1.3-3.9; p = 0.006). The decision-board only marginally improved patient knowledge and doctor-patient communication. In conclusion, large proportions of psoriasis patients want to participate in decision-making, but insufficient patient knowledge can represent a barrier

The right place. Solid waste management in the Republic of Maldives: between infrastructural measures and local practices

Abstract The 2010 UNPD's Assessment of Development Results defined the Maldives "a vulnerable Small Island Developing State" by pointing out the influence of both external and local human factors on their fragile ecosystems. This impact is deeply related to a main geographical feature: the high dispersion of land mass and population, both of them spread over a distance of 860 km. Above all, this dispersion has an effect on two environmental issues: energy distribution and solid waste management. The latter is particularly interesting for the geographical analysis of Small Island Countries. Due to centre-periphery distance and cost benefits analysis, in the Maldives public and private actors have developed different solid waste management models: central and regional waste management dumpsites, hybrid systems implemented by resorts and "informal" practices still followed by local communities. In this paper, we discuss these systems stressing on the relevance of combining infrastructural measures with "informal" practices at local level. Furthermore, we report the outcomes of The Right Place, a participatory waste management action carried out by MaRHE Center (a Milano- Bicocca Research Center) in Faafu Magoodhoo Island

Beam manipulation for resonant plasma wakefield acceleration

Plasma-based acceleration has already proved the ability to reach ultra-high accelerating gradients. However the step towards the realization of a plasma-based accelerator still requires some e ff ort to guarantee high brightness beams, stability and reliability. A significant improvement in the efficiency of PWFA has been demonstrated so far accelerating a witness bunch in the wake of a higher charge driver bunch. The transformer ratio, therefore the energy transfer from the driver to the witness beam, can be increased by resonantly exciting the plasma with a properly pre-shaped drive electron beam. Theoretical and experimental studies of beam manipulation for resonant PWFA will be presented her

Surface Immobilized His-tagged Azurin as a Model Interface for the Investigation of Vectorial Electron Transfer in Biological Systems

A model system for the electrochemical investigation of vectorial electron transfer in biological systems was designed, assembled and characterized. Gold electrodes, functionalized with a -OCH3 terminated, aromatic self-assembled monolayer, were used as a substrate for the adsorption of variants of copper- containing, redox metalloprotein azurin. The engineered azurin bears a polyhistidine tag at its C-terminus. Thanks to the presence of the solvent exposed tag, which chelates Cu2+ ions in solution, we introduced an exogenous redox centre. The different reduction potentials of the two redox centres and their positioning with respect to the surface are such that electron transfer from the exogenous copper centre and the electrode is mediated by the native azurin active site, closely paralleling electron transfer processes in naturally occurring multicentre metalloprotein