L'Osservatorio Geofisico di Lipari ed i 40 anni della Rete Sismica Permanente del Tirreno Meridionale

In 1966, the Istituto Internazionale di Vulcanologia (I.I.V.), gave the go ahead to the ambitious project of setting up a seismic network in the southern Tyrrhenian Sea, an area of extraordinary geophysical interest, which until then was not covered by seismic monitoring. At the time, there were single seismic stations on the rest of the italian peninsula. These were inside universities, public and private bodies and at the numerous observatories of the Istituto Nazionale di Geofisica (founded in 1936 by Antonino Lo Surdo and becoming independent of the Consiglio Nazionale delle Ricerche (C.N.R,. in 1945) and still used mechanical seismographs, with masses weighing from 80 up to 1300 Kg. On the Aeolian Islands instead, electromagnetic seismometers were employed from the start. The experimental network, planned in the Willmore laboratories at Edinburgh and tested in the Aeolian Islands over a two-year period, represented the starting point for the Permanent Seismic Network (PSN) of the Southern Tyrrhenian. After the experience of the Laboratorio Internazionale per le Ricerche Vulcanologiche (L.I.R.V. - C.N.R.), of the Istituto di Vulcanologia of the University of Catania, the independent I.I.V. - C.N.R., together with the observatory, was launched in 1969. In the course of the seventies, every island of the Aeolian archipelago, was equipped with at least a seismic station and the 3 sensor systems (triaxial systems) began to become widely used. In the eighties, the “Sismologia Eolie” project was started, aimed at a further develop and update the seismic net. With the wide use of magnetic tape recording, the instrumental data stored could be more readily transported on suitable drums to the main centre in Catania for analysis. Here, Research Units were established in order to prepare the way for enhanced interaction between technical staff and research groups. The instrumental geophysical investigations, progressively extended and in a permanente form to Eastern Sicily and particular around Etna. From the nineties, operations room in Catania was fully active, working 24/24, and ensuring the seismic and volcanic surveillance of Etna, Stromboli and Vulcano. The Geophysical Observatory of Lipari and the main centre of the Institute in Catania, were merged in 2001 into the new Istituto Nazionale di Geofisica e Vulcanologia (INGV) and the network of the Aeolian Islands became an integral part of the Permanent Seismic Network (PSN) of Eastern Sicily and Southern Calabria. Special prominence will be given in the course of this historical reconstruction to the evolution of instrumental seismology, thanks to forty years of continuous input, indispensable for the understanding of the seismogenetic processes in the area, this still represents the chief undertaking of the geophysical observatory on Lipari, whose important scientific but also social role must be acknowledged in the growing interaction between research and civil protection

Improvement of resveratrol permeation through sublingual mucosa: Chemical permeation enhancers versus spray drying technique to obtain fast-disintegrating sublingual mini-tablets

Resveratrol (RSV) is a natural polyphenol with several interesting broad-spectrum pharmacological properties. However, it is characterized by poor oral bioavailability, extensive first-pass effect metabolism and low stability. Indeed, RSV could benefit from the advantage of the sublingual route of administration. In this view, RSV attitudes to crossing the porcine sublingual mucosa were evaluated and promoted both by six different chemical permeation enhancers (CPEs) as well as by preparing four innovative fast-disintegrating sublingual mini-tablets by spray drying followed by direct compression. Since RSV by itself exhibits a low permeation aptitude, this could be significantly enhanced by the use of CPEs as well as by embedding RSV in a spray-dried powder to be compressed in order to prepare fast-disintegrating mini-tablets. The most promising observed CPEs (menthol, lysine and urea) were then inserted into the most promising spray-dried excipients’ compositions (RSV-B and RSV-C), thus preparing CPE-loaded mini-tablets. However, this procedure leads to unsatisfactory results which preclude the possibility of merging the two proposed approaches. Finally, the best spray-dried composition (RSV-B) was further evaluated by SEM, FTIR, XRD and disintegration as well as dissolution behavior to prove its effectiveness as a sublingual fast-disintegrating formulation

Straw mulch as a sustainable solution to decrease runoff and erosion in glyphosate-treated clementine plantations in Eastern Spain. An assessment using rainfall simulation experiments

[EN] In many Mediterranean areas, citrus orchards exhibit high soil loss rates because of the expansion of drip irrigation that allows cultivation on sloping terrain and the widespread use of glyphosate. To mitigate these non-sustainable soil losses, straw mulch could be applied as an efficient solution but this has been poorly studied. Therefore, the main goal of this paper was to assess the use of straw mulch as a tool to reduce soil losses in clementine plantations, which can be considered representative of a typical Mediterranean citrus orchard. A total of 40 rainfall simulation experiments were carried out on 20 pairs of neighbouring bare and mulched plots. Each experiment involved applying 38.8 mm of rain at a constant rate over 1 h to a circular plot of 0.28 m(2) circular plots. The results showed that a cover of 50% of straw (60 g m(-2)) was able to delay the time to ponding from 32 to 52 s and the time to runoff initiation from 57 to 129 s. Also, the mulching reduced the runoff coefficient from 65.6 to 50.5%. The effect on sediment transport was even more pronounced, as the straw mulch reduced the sediment concentration from 16.7 g l(-1) to 3.6 g l(-1) and the soil erosion rates from 439 g to 73 g. Our results indicated that mulching can be used as a useful management practice to control soil erosion rates due to the immediate effect on high soil detachment rate and runoff initiation reduction in conventional clementine orchards on sloping land, by slowing down runoff initiation and by reducing runoff generation and, especially, sediment losses. We indirectly concluded that straw mulch is also a sustainable solution in glyphosate-treated citrus plantations.This paper is part of the results of research projects GL2008-02879/BTE, LEDDRA 243857 and RECARE-FP7 (ENV.2013.6.2-4).Keesstra, S.; Rodrigo-Comino, J.; Novara, A.; Giménez Morera, A.; Pulido, M.; Di Prima, S.; Cerda, A. (2019). Straw mulch as a sustainable solution to decrease runoff and erosion in glyphosate-treated clementine plantations in Eastern Spain. An assessment using rainfall simulation experiments. CATENA. 174:95-103. https://doi.org/10.1016/j.catena.2018.11.007S9510317

Long-term trial of tillage systems for sugarcane: Effect on topsoil hydrophysical attributes

Seeking to provide essential information about sustainable tillage systems, this work aimed to assess the effects of liming and soil cultivation systems on the soil hydrophysical attributes of a long-term cultivated sugarcane field in the tropical region of southeast Brazil. Infiltration tests and soil sampling down to 0.10 m were performed in order to determine saturated soil hydraulic conductivity, soil bulk density, soil total porosity, macroporosity, microporosity, and soil resistance to penetration. The studied areas include no-tillage (NT) and conventional tillage (CT) systems with 0 (CT0 and NT0) and 4 (CT4 and NT4) Mg ha-1 of lime, and an adjoining area with native forest (NF). The data analysis included an analysis of variance followed by the Tukey test to compare different systems, assessment of the Pearson correlation coefficient between variables, and a principal component analysis of the dataset. The lowest bulk density and highest soil total porosity, macroporosity and saturated hydraulic conductivity were found in the NF. The bulk density in CT4 and NT0 was higher than in other systems, indicating the need for amelioration. NT4 is suggested as the most viable system for conservation agriculture in sugarcane fields, combining the benefits of no-tillage and liming to enhance soil hydrophysical functions

Anti-Transglutaminase Antibody Assay of the Culture Medium of Intestinal Biopsy Specimen Can Improve the Accuracy of Celiac Disease Diagnosis.

BACKGROUND: We measured anti-transglutaminase (anti-tTG) antibody in the culture medium of intestinal biopsy specimens from patients with suspected celiac disease (CD) and evaluated the relationship between antibody production and severity of intestinal mucosal damage. METHODS: We performed diagnostic testing for CD on 273 consecutive patients. In addition to routine histologic evaluation of duodenal biopsy specimens, we assayed anti-tTG antibodies in serum and in the culture medium of duodenal biopsy specimens. RESULTS: CD was diagnosed in 191 of the 273 patients. Sensitivity and specificity of the serum anti-endomysium (EmA) and anti-tTG assays were 83% and 85% and 99% and 95%, respectively, and both had 88% diagnostic accuracy. EmA and anti-tTG assayed in the culture medium had 98% sensitivity, 100% specificity, and 98% diagnostic accuracy (vs serum assays; P <0.0001). Twenty-nine CD patient specimens (16%) were negative for serum anti-tTG and EmA; for 24 of these patients, anti-tTG assay of the culture medium was positive. The CD patients whose biopsy specimens were positive for serum antibodies showed the following intestinal histologies: total villous atrophy, 35%; severe villous atrophy, 25%; mild atrophy, 25%; villi with no atrophy but with increased intraepithelial lymphocytes, 15%. None of the CD patients whose specimens were negative for serum antibodies showed total or severe villous atrophy; 77% had mild villous atrophy, and 23% had no villous atrophy but had increased intraepithelial lymphocyte counts. Mild villous atrophy was also seen in specimens from approximately 15% of patients without CD. CONCLUSION: Anti-tTG assay of the culture medium of biopsy specimens can improve the accuracy of CD diagnosis in patients negative for serum antibodies

Does the process of passive forest restoration affect the hydrophysical attributes of the soil superficial horizon?

There has been an increase in the area of secondary tropical forests in recent years due to forest restoration in degraded areas. Recent analyses suggest that the success of passive forest restoration is highly uncertain and needs to be better understood. This study aimed to investigate the behavior of saturated hydraulic conductivity (Ks) and some hydrophysical soil attributes between agricultural land uses, restored forests, and a degraded forest fragment. The areas evaluated are located in the municipality of Rio Claro, Sao Paulo, Brazil, under different types of land use: (i) two areas in the process of passive forest restoration: one of 18 and another of 42 years (NR18 and NR42); (ii) a degraded forest fragment (FFD); (iii) pasture (P), and (iv) sugarcane (SC). The hydraulic soil conductivity characterization was performed using the Beerkan method. Dry soil bulk density (BD), total porosity (Pt), macroporosity (Mac), microporosity (Mic), penetration resistance (PR), mean aggregate diameter (MWD), and soil organic carbon (OC) were also determined. The comparative analysis of the hydrophysical attributes of the soil superficial horizon in agricultural land uses (P and SC), restored forests (NR18 and NR42), and a degraded forest (DFF) confirms that the recovery of soil hydrological functioning in ongoing forest restoration processes can be a relatively slow process. In addition, the intensity of previous land use leaves footprints that can affect passive restoration areas for decades after agriculture abandonment, increasing the time for the recovery of Ks and soil hydrophysical attributes

Lipid nanocarriers-loaded nanocomposite as a suitable platform to release antibacterial and antioxidant agents for immediate dental implant placement restorative treatment

Immediate implant placement is a single-stage restorative approach for missing teeth widely used to overcome the ridge remodeling process occurring after dental extractions. The success of this procedure relies on opportune osseointegration in the surrounding tissues. To support this process, a multifunctional nanocomposite, to be applied in the fresh post-extraction socket, was here designed, prepared, and characterized. This formulation consists of quercetin (QRC)-loaded nanostructured lipid carriers (NLCs) entrapped in a chitosan-based solid matrix containing ciprofloxacin (CPX). QRC-NLCs were prepared by homogenization followed by high-frequency sonication, and thereafter this dispersion was trapped in a chitosan-based CPX-loaded gel, obtaining the nanocomposite powder (BioQ-CPX) by lyophilization. BioQ-CPX displayed desirable properties such as high porosity (94.1 ± 0.5%), drug amounts (2.1% QRC and 3.5% CPX). and low swelling index (100%). Moreover, the mechanism of drug release from BioQ-CPX and their ability to be accumulated in the target tissue were in vitro and ex vivo elucidated, also by applying mathematical models. When trapped into the nanocomposite, QRC stressed under UV light exposure (50 W) was shown to maintain its antioxidant power, and CPX and QRC under natural light were stable over nine months. Finally, both the measured antioxidant power and the antimicrobial and antibiofilm properties on Staphylococcus aureus demonstrated that BioQ-CPX could be a promising platform to support the single-stage dental restorative treatment