BepiColombo MPO Electro Magnetic Compatibility (EMC) Conducted Emission (CE) Test at ESTEC 09/09/2015 – 11/09/2015 SERENA Instrument Summary Report

Issue: 1 , Revision: 0 , date: 23/09/2015 , Delivered to: ESA/ESTECThis is the test report describing the measure collected by the SERENA PI egse, during the Electro Magnetic Compatibility (EMC) Conducted Emission (CE) Test in the test centre room (“Rosetta Clean Room”) at ESTEC, Noordwijk (NL). The objective of the Conducted EMC test is to demonstrate that BepiColombo is: Compliant with the BepiColombo satellite level requirements as per [RD3] BC-ASD-TS-00014 Issue 02 "MPO/MCS EMC Functional Verification Specification", Compatible with the conducted emission requirements, re-checking unit and instrument EMC behavior on spacecraft level , self-compatible with the conducted emission and susceptibility thresholds

Performance analysis of the GR712RC dual-core LEON3FT SPARC V8 processor in an asymmetric multi-processing environment

In this paper we present the results of a series of performance tests carried out on a prototype board mounting the Cobham Gaisler GR712RC Dual Core LEON3FT processor. The aim was the characterization of the performances of the dual core processor when used for executing a highly demanding lossless compression task, acting on data segments continuously copied from the static memory to the processor RAM. The selection of the compression activity to evaluate the performances was driven by the possibility of a comparison with previously executed tests on the Cobham/Aeroflex Gaisler UT699 LEON3FT SPARC™ V8. The results of the test activity have shown a factor 1.6 of improvement with respect to the previous tests, which can easily be improved by adopting a faster onboard board clock, and provided indications on the best size of the data chunks to be used in the compression activity

ELENA instrument science and testing: validation with particle beam

Understanding of particle emission processes from the Mercury surface is one of the major objectives of ELENAinstrument in the SERENA experiment on board of the BepiColombo mission. In particular the Ion-Sputteringprocess resulting from charged and energetic particles impacting on the surface can be investigated detectingthe low energetic neutral particles escaping from the planet. The possibility to identify the Ion-Sputtering signaltogether with back-scattered particles and neutrals generated by charge exchange is strictly linked with the newtechnology capability to measure low energetic neutral atoms. This goal can be addressed thanks to a new&oldapproach for the neutral atoms measurement: a well known Time of Flight system enhanced with a new kind ofStart section able to define the start time of the entrance in the ToF path without interacting with the particles anddirectly follow to the Stop detector. The Start section is a shutter composed by two membranes with nanometricslits realized in a large area (1cm2) and oscillating at several frequencies to open and close the entrance of ToFsection. This system is never used before in space mission.The IFSI-INAF Ion beam facility in Rome is devoted to the ELENA testing. The crucial point of the shutteringsystem interaction with particle beam is investigated. The first results demonstrate the good functionality of thiskind of system: capability of the shutter to Open and Close the entrance respect to an ion beam is tested with aMCP stop detector. In this poster we present the IFSI activity in the frame of ELENA science requirement togetherwith the experimental activity devoted to instrument verification

The rapid spread of SARS-COV-2 Omicron variant in Italy reflected early through wastewater surveillance

The SARS-CoV-2 Omicron variant emerged in South Africa in November 2021, and has later been identified worldwide, raising serious concerns. A real-time RT-PCR assay was designed for the rapid screening of the Omicron variant, targeting characteristic mutations of the spike gene. The assay was used to test 737 sewage samples collected throughout Italy (19/21 Regions) between 11 November and 25 December 2021, with the aim of assessing the spread of the Omicron variant in the country. Positive samples were also tested with a real-time RT-PCR developed by the European Commission, Joint Research Centre (JRC), and through nested RT-PCR followed by Sanger sequencing. Overall, 115 samples tested positive for Omicron SARS-CoV-2 variant. The first occurrence was detected on 7 December, in Veneto, North Italy. Later on, the variant spread extremely fast in three weeks, with prevalence of positive wastewater samples rising from 1.0% (1/104 samples) in the week 5-11 December, to 17.5% (25/143 samples) in the week 12-18, to 65.9% (89/135 samples) in the week 19-25, in line with the increase in cases of infection with the Omicron variant observed during December in Italy. Similarly, the number of Regions/Autonomous Provinces in which the variant was detected increased from one in the first week, to 11 in the second, and to 17 in the last one. The presence of the Omicron variant was confirmed by the JRC real-time RT-PCR in 79.1% (91/115) of the positive samples, and by Sanger sequencing in 66% (64/97) of PCR amplicons. In conclusion, we designed an RT-qPCR assay capable to detect the Omicron variant, which can be successfully used for the purpose of wastewater-based epidemiology. We also described the history of the introduction and diffusion of the Omicron variant in the Italian population and territory, confirming the effectiveness of sewage monitoring as a powerful surveillance tool

Cost-effective and disposable label-free voltammetric immunosensor for sensitive detection of interleukin-6

IL-6 detection is highly desirable since can monitor many diseases in humans and assess the response to treatments.Herein, two novel label-free voltammetric immunosensors for rapid and accurate interleukin-6 (IL-6) detection in human serum are presented. The immunosensors are fabricated by immobilising two different IL-6 antibodies, identified as mAb-IL-6 clone-5 and clone-7, on in-house produced screen-printed electrodes modified with inexpensive recycling biochar (Bio-SPEs). To ensure high structural fidelity and performance, an in-depth electrochemical characterization of the layer-by-layer assembly of the immunosensor was conducted by cyclic voltammetry (CV) and sensing was performed using square wave voltammetry (SWV). The two immunosensors showed good analytical performances in human serum, exhibiting a wide linear range (LR) between 26-125 and 30-138 pg/mL, a good limit of detection (LOD) of 4.8 and 5.4 pg/mL and selectivity for IL-6 over other common cytokines, including IL-1 beta and TNF-alpha. Performance comparison of IL-6 immunosensors with those of a commercial spectrophotometric ELISA kit (LOD of 20 pg/mL, RSD% of 15%) denotes a better sensitivity and reproducibility of the proposed label-free devices, associated with a reduced detection time (30 min instead of more than 3 h for ELISA test). Furthermore, the proposed immunosensors were successfully applied in blood samples (with only a dilution of 1:100 v/v in PBS and without additional treatments) with good sensitivity (LOD of 14.3 pg/mL) and reproducibility (RSD% < 11%), thus paving the way for their application as viable diagnostic and therapeutic point-of-care tools alternative to the IL-6 detection techniques routinely used (ELISA and Western Blot)

An inverse-designed electrochemical platform for analytical applications

Screen-printed electrodes are the most recent generation of low-cost, mass-produced, sensitive and portable devices for the measurement of analytes of interest. The responses of these platforms, in terms of current intensity and reproducibility, are strongly influenced by factors such as printing procedures, type of ink, substrates, etc. In this paper, an improved inverse-designed screen-printed electrode (IDSPE) is proposed. The electrochemical performance is compared with that obtained using classical screen printed electrodes (SEPs), showing enhanced sensitivity and signal-to-noise ratio (background current minimization 32 ± 3 nA and 0.64 ± 0.01 nA, for SPE and IDSPE, respectively). A full comparison between inverse and classical screen-printed electrodes is carried out using various electroactive species (potassium ferricyanide, ascorbic acid, hexaammineruthenium(III) chloride and NADH) and two different electrochemical techniques (cyclic and square-wave voltammetry). In tests conducted with potassium ferricyanide the sensitivity of the IDSPE shows a nearly four-fold improvement, and a limit of detection three times better than the values obtained employing the classical SPE. The reproducibility (RSD%) in tests conducted with ascorbic acid is 6% and 12% for IDSPE and SPE, respectively. Moreover, surface modification of both screen-printed electrodes (SPE and IDSPE) with biochar obtained from recycled brewers waste (Bio-SPEs and Bio-IDSPEs), further improves their electrochemical performance, in terms, for example, of the heterogeneous electron transfer constant (0.0024 and 0.0018 for Bio-SPE and Bio-IDSPE, respectively)

The BepiColombo SERENA/ELENA unit development: a new technique to detect sputtered neutral atoms escaping from Mercury surface

ELENA (Emitted Low-Energy Neutral Atoms) is one of the four units of the SERENA experiment for the ESAcornerstone BepiColombo mission to Mercury. It is primarily devoted to understanding of Ion Sputtering processesand emission from planetary surfaces, particle back-scattering and Charge Exchange via neutral atoms detectionsin the energy range ? 20 eV - 5 keVELENA instrument is the first attempt of a new design techniques approached for the neutral particles identificationin the low energy range. It is a Time-of-Flight system based on a peculiar Start section: an oscillating shutter(operated at frequencies up to a 100 kHz) and mechanical grating (two self-standing silicon nitride (Si3N4)membranes, patterned with arrays of long and narrow openings) that allows to identify the start time of theparticles entering in the Time-of-Flight chamber. The Stop section at the end of the pattern is a 1-dimensionalarray composed by MCPs detector with discrete anodes corresponding to a Field of View of 4,5?x76?. This systemallows having the determination of velocity and direction of the incoming particles.The instrument has a good capability to reject UV photons with the start section and to reject charged particle witha deflector system.In this paper the crucial parts of the instrument and test results will be described: the nano-structure membranesmanufacturing, the shuttering system, the position encoder, the optical propriety of the membranes, the photonand particle test, the electronic box

An Integrated System for Large Scale Scanning of Nuclear Emulsions

The European Scanning System, developed to analyse nuclear emulsions at high speed, has been completed with the development of a high level software infrastructure to automate and support large- scale emulsion scanning. In one year, an average installation is capable of performing data-taking and online analysis on a total surface ranging from few m2 to tens of m2, acquiring many billions of tracks, corresponding to several TB. This paper focuses on the procedures that have been implemented and on their impact on physics measurements. The system proved robust, reliable, fault-tolerant and user- friendly, and seldom needs assistance. A dedicated relational Data Base system is the backbone of the whole infrastructure, storing data themselves and not only catalogues of data files, as in common practice, being a unique case in high-energy physics DAQ systems. The logical organisation of the system is described and a summary is given of the physics measurement that are readily available by automated processing