eta - eta prime Mixing -From electromagnetic transitions to weak decays of charm and beauty hadrons

It has been realized for a long time that knowing the eta and eta^prime wave functions in terms of quark and gluon components probes our understanding of non-perturbative QCD dynamics. Great effort has been given to this challenge -- yet no clear picture has emerged even with the most recent KLOE data. We point out which measurements would be most helpful in arriving at a more definite conclusion. A better knowledge of these wave functions will significantly help to disentangle the weight of different decay subprocesses in semi-leptonic decays of D+, Ds^+ and B+ mesons. The resulting insights will be instrumental in treating even non-leptonic B transitions involving eta and eta^prime and their CP asymmetries; thus they can sharpen the case for or against New Physics intervening there.Comment: 22 pages, 4 figures; it matches published versio

Has immigration really led to an increase in crime in Italy?

Immigration has been a key topic in Italy's election campaign, with several candidates arguing that the flow of people into the country during the migration crisis has increased the risk of crime. But has immigration really generated more crime in Italy? Drawing on data from the Italian National Institute of Statistics, Donato Di Carlo, Julia Schulte-Cloos and Giulia Saudelli illustrate that crime rates across Italian regions and the share of crimes committed by foreigners have both fallen significantly over the last decade

Effects of transcranial alternating current stimulation on repetitive finger movements in healthy humans

Transcranial alternating current stimulation (tACS) is a noninvasive neurophysiological technique that can entrain brain oscillations. Only few studies have investigated the effects of tACS on voluntary movements. We aimed to verify whether tACS, delivered over M1 at beta and gamma frequencies, has any effect on repetitive finger tapping as assessed by means of kinematic analysis. Eighteen healthy subjects were enrolled. Objective measurements of repetitive finger tapping were obtained by using a motion analysis system. M1 excitability was assessed by using single-pulse TMS and measuring the amplitude of motor-evoked potentials (MEPs). Movement kinematic measures and MEPs were collected during beta, gamma, and sham tACS and when the stimulation was off. Beta tACS led to an amplitude decrement (i.e., progressive reduction in amplitude) across the first ten movements of the motor sequence while gamma tACS had the opposite effect. The results did not reveal any significant effect of tACS on other movement parameters, nor any changes in MEPs. These findings demonstrate that tACS modulates finger tapping in a frequency-dependent manner with no concurrent changes in corticospinal excitability. The results suggest that cortical beta and gamma oscillations are involved in the motor control of repetitive finger movements

Clinical, Histological and Trichoscopic Correlations in Scalp Disorders

Trichoscopy is the term coined for the dermoscopic imaging of scalp and hair. This diagnostic technique, simple and noninvasive, can be used as a handy bedside tool for the diagnosis and follow-up of hair and scalp disorders. It allows the recognition of morphologic structures not visible by the naked eye and provides the clinician with a range of dermoscopic findings necessary for differential diagnosis. Trichoscopy observation can be broadly grouped as interfollicular patterns and follicular patterns. Recently, a third mixed class, called the follicular plus interfollicular pattern, has been introduced. Some of these features are specific to a certain scalp disease, while others can be found in many hair disorders. Although studies suggest that the use of trichoscopy can improve clinical accuracy, further investigation is needed. This review provides update information on the trichoscopic features of the most common scalp disorders, striving to show a histopathological and clinical correlation

Efficacy of milbemycin oxime/afoxolaner chewable tablets (NEXGARD SPECTRA®) against Capillaria aerophila and Capillaria boehmi in naturally infected dogs

BACKGROUND: Capillaria aerophila and Capillaria boehmi parasitize the respiratory system of wild and domestic carnivores. Capillaria aerophila inhabits the trachea and bronchi of dogs and cats, while C. boehmi affects the nasal cavities and sinuses of dogs. In dogs the infection may be subclinical or characterized by varying respiratory distress.METHODS: The present study evaluated the efficacyof an oral formulation containing milbemycin oxime and afoxolaner (NEXGARD SPECTRA) in dogs naturally infected with C. aerophila and/or C. boehmi from three enzootic areas of Italy. Dogs were enrolled pending fecal examination and molecular confirmation of respiratory capillarioses. Dogs were allocated in two groups: Group 1 (G1, 25 dogs), treated with a negative control product with no anthelmintic activity (afoxolaner, NEXGARD), and Group 2 (G2, 26 dogs), treated with NEXGARD SPECTRA. At the day of treatment administration (Day 0), all dogs were clinically examined. Dogs were again subjected to clinical and fecal examinations at Days 28 (±4) and 56 (±2). The primary criterion for treatment efficacy was the reduction of fecal Capillaria egg counts in G2 compared with G1. The regression of/recovery from baseline clinical signs was considered as a further efficacy criterion.RESULTS: Percentage reduction of fecal Capillaria egg counts in the NEXGARD SPECTRA group compared to the control group was >97% on Day 28 and 100% on Day 56, respectively (p<0.05 for both time points). Twelve of the 13 dogs in the NEXGARD SPECTRA group with respiratory signs prior to treatment were free of clinical signs at the end of the study. Conversely, the six control group dogs with respiratory signs prior to treatment remained symptomatic.CONCLUSIONS: Results of the present study showed that NEXGARD SPECTRA was safe and highly efficacious in the reduction of C. aerophila and C. boehmi eggs after one treatment with a complete reduction of the egg output after the second administration associated with a recovery from respiratory signs

Contamination of Italian parks with canine helminth eggs and health risk perception of the public

Abstract The contamination of public areas by dog faeces is a social behaviour and public health problem. In fact, the most frequently isolated intestinal helminths in dogs are distributed worldwide, and most of them have zoonotic potential (i.e., ascarids and ancylostomatids). The aims of this survey were to evaluate citizen awareness of health risks for animals and humans related to canine faecal pollution and to estimate the presence and prevalence of intestinal helminths in dog faeces collected in green public areas in three municipalities of Italy (Padua, Rome and Teramo). The awareness of citizens about the health risks related to faecal pollution was evaluated using questionnaires submitted to 313 dog owners and 159 non-dog owners in Padua (n = 341) and Rome (n = 131). Most dog owners (85.4%) declared they picked up their dog's faeces every time, and these data were confirmed by operators secretly observing dog owners. Moreover, 84.3% participants were aware of the existence of a municipal regulation concerning the correct management of animals in public areas with no significant differences between dog owners and non-dog owners, whereas Rome citizens were significantly more aware than Padua citizens. Nonetheless, only 10.9% (51/469) of responders knew the health risks related to canine faecal pollution, with no significant differences between dog and non-dog owners. A total of 677 dog stool samples were collected and copromicroscopically analysed. Forty-eight (7.1%) samples were positive for at least one parasite species, with significantly lower prevalence values in Padua (2.2%) than in Rome (11.9%) and Teramo (8.6%). The highest prevalence was detected for Trichuris vulpis (4.4%), followed by Toxocara canis (1.9%); T. vulpis presented significantly lower prevalence in Padua than in the other cities. Other helminths were found with values under 0.5% in the investigated cities. This survey shows that most citizens are unaware of the health risk related to abandoned canine faeces on public soils. Nevertheless, laboratory results suggest a limited risk for dog and human health, but the zoonotic risk due to the high vitality of infective helminths eggs in the soil should always be considered

Performance of Circulating Placental Growth Factor as A Screening Marker for Diagnosis of Ovarian Endometriosis: A Pilot Study

The aim of this study is to compare the circulating placental growth factor (PlGF) concentration in women with and without endometrioma to verify the performance of this marker to diagnose the disease

Prevalence of zoonotic helminths in Italian house dogs.

Introduction: Dogs may act as potential sources of zoonotic parasites, e.g. intestinal helminths like Toxocara spp., Ancylostoma spp., Echinococcus spp. In particular circumstances, the environment contaminated by parasitic elements represents a source of infection for people and animals. The present study has evaluated the presence of zoonotic helminths in house dogs from central and north-eastern Italy. Methodology: Stool samples from 493 dogs were examined by a qualitative copromicroscopic technique and differences in prevalence of zoonotic parasites were statistically examined in relation to canine individual data. Results: 48/493 (9.7%) were positive for at least one parasite. Helminths recovered were Trichuris vulpis (5.5%), Toxocara canis (4.3%), Ancylostoma spp. (0.6%) and Eucoleus aerophilus (0.4%), while no cestodes were detected. Age and living with other dogs resulted risk factors for T. canis infection. Conclusions: The health risk associated with the occurrence of parasitic nematodes in privately owned dogs, along with the current anthelmintic treatment plans, are discussed

The Internationalisation of Higher Education in the Mediterranean

The internationalisation of higher education is aimed at enhancing the quality and standards of teaching and research. This study addresses mobility and cross-border education trends in the Euro-Mediterranean region, with special emphasis on academic exchange, involving students, scholars and administrative staff, as well as on the strategic international partnerships across the globe. The study focuses on 10 countries: Algeria, Egypt, Israel, Jordan, Lebanon, Libya, Mauritania, Morocco, Palestine and Tunisia. It aims to investigate the internationalisation of higher education focusing especially on resources and opportunities available at the national and regional levels, to identify obstacles and challenges and to outline transferable inspiring practices and finally to make a series of recommendations for the Union for the Mediterranean to foster regional integration. As for the methodology, a survey investigating teaching and administrative staff as well as student mobility was submitted to a sample of universities representing the 10 target countries; further interviews with international and regional stakeholders were conducted, focus groups were established, involving the universities covered by the study and a thorough desk research was undertaken. As a result, the report presents a detailed context analysis with a focus on mobility flows to and from the 10 target countries, complemented by a wide range of inspiring and scalable practices, as well as an overview of the role played by regional organisations in providing opportunities, creating synergies and making resources available for the higher education institutions in the Mediterranean. Country-specific recommendations were designed in order to address national challenges. At the end of the research and consultative process, a number of common themes for the Euro-Mediterranean region were also identified, in relation to which additional recommendations were drafted, with the aim of enhancing the internationalisation of higher education in the region. We are still far from the finish line and this report has the ambitious goal to represent a building block for those willing to further explore the issue. Here follow the main findings, which are common to more than one country: Erasmus+ emerged as the programme generating the largest impact on the internationalisation strategies of higher education institutions; the need for university leadership to consider the administrative staff as a key element to support internationalisation; the high fragmentation in the procedures and systems of credit recognition and assessment of qualifications; difficulties were encountered in collecting reliable and comparable data. Obtaining visas for international mobility, especially for MENA countries to access Europe, has always been a serious obstacle to exchanges and international cooperation should focus more on human and social sciences, often neglected compared to hard sciences. Above all, the study highlights how, in most cases, internationalisation is simply identified as mobility, while a more comprehensive internationalisation strategy would be highly beneficial for institutions and staff and may increase attractiveness and participation

Porphyrins Through the Looking Glass: Spectroscopic and Mechanistic Insights in Supramolecular Chirogenesis of New Self-Assembled Porphyrin Derivatives

The solvent driven aggregation of porphyrin derivatives, covalently linked to a L- or D-prolinate enantiomer, results in the stereospecific formation of species featuring remarkable supramolecular chirality, as a consequence of reading and amplification of the stereochemical information stored in the proline-appended group. Spectroscopic, kinetic, and topographic SEM studies gave important information on the aggregation processes, and on the structures of the final chiral architectures. The results obtained may be the seeds for the construction of stereoselective sensors aiming at the detection, for example, of novel emergent pollutants from agrochemical, food, and pharmaceutical industry