Seismic Response Analysis of Continuous Multispan Bridges with Partial Isolation

Partially isolated bridges are a particular class of bridges in which isolation bearings are placed only between the piers top and the deck whereas seismic stoppers restrain the transverse motion of the deck at the abutments. This paper proposes an analytical formulation for the seismic analysis of these bridges, modelled as beams with intermediate viscoelastic restraints whose properties describe the pier-isolator behaviour. Different techniques are developed for solving the seismic problem. The first technique employs the complex mode superposition method and provides an exact benchmark solution to the problem at hand. The two other simplified techniques are based on an approximation of the displacement field and are useful for preliminary assessment and design purposes. A realistic bridge is considered as case study and its seismic response under a set of ground motion records is analyzed. First, the complex mode superposition method is applied to study the characteristic features of the dynamic and seismic response of the system. A parametric analysis is carried out to evaluate the influence of support stiffness and damping on the seismic performance. Then, a comparison is made between the exact solution and the approximate solutions in order to evaluate the accuracy and suitability of the simplified analysis techniques for evaluating the seismic response of partially isolated bridges

Finite elements for higher order steel–concrete composite beams

none4noThis paper presents finite elements for a higher order steel–concrete composite beam model developed for the analysis of bridge decks. The model accounts for the slab–girder partial interaction, the overall shear deformability, and the shear‐lag phenomenon in steel and concrete components. The theoretical derivation of the solving balance conditions, in both weak and strong form, is firstly addressed. Then, three different finite elements are proposed, which are characterised by (i) linear interpolating functions, (ii) Hermitian polynomial interpolating functions, and (iii) interpolating functions, respectively, derived from the analytical solution expressed by means of exponential matrices. The performance of the finite elements is analysed in terms of the solution con-vergence rate for realistic steel–concrete composite beams with different restraints and loading con-ditions. Finally, the efficiency of the beam model is shown by comparing the results obtained with the proposed finite elements and those achieved with a refined 3D shell finite element model.openGara F.; Carbonari S.; Leoni G.; Dezi L.Gara, F.; Carbonari, S.; Leoni, G.; Dezi, L

Pengaruh Volume Cairan Rumen Sapi Terhadap Bermacam Feses Dalam Menghasilkan Biogas

This research is aimed at investigating the influence of cow's rumen fluid volume toward varied feces in producing biogas. This research has been done since October to December 2013 at Biotechnology laboratory, Faculty and Mathematic Science. The method of this research was completely randomized design (CRD) with factorial in three times. The first factor as the treatment was the type of feces, such as cow, horse, goat, and buffalo's feces. The second factor was the treatment by adding the volume of cow's rumen liquid as many as 160 and 320 ml. The control was the treatment without adding the volume of cow's rumen liquid. The variables that were measured in this research were the volume of biogas and the duration of biogas flame that could be produced. The result of this research shows that the type of feces affected the biogas production. In these treatments, the highest volume of biogas that was produced to the lowest were horse's feces yield of 226.56 cm3, cow's feces yield of 71.40 cm3, buffalo's feces yield of 28.28 cm3, and goat's feces yield of 2.13 cm3. The addition of rumen liquid can increase the biogas production on cow, goat, and buffalo's feces, but it did not significantly give the effect on horse's feces. The positive interaction between addition of rumen liquid and feces shows on cow, goat, and buffalo's feces. The rumen liquid, however, was not interacted with horse's feces for producing biogas

Acute occlusion of descending thoracic aorta

Acute aortic occlusion is a rare but potentially devastating clinical event, which requires a prompt diagnosis and emergency treatment. Only 5 cases of native thoracic aorta acute occlusion have so far been reported with different pathologic causes. The clinical features depend on the level of occlusion. Sometimes the diagnosis could be misinterpreted as a stroke or other diseases of the central nervous system. This could lead to a delay in the diagnosis and revascularization procedure, followed by a morbidity or mortality increase. Open surgery has been considered the first-line approach. This study is of a female patient suffering from acute descending thoracic aorta occlusion undergoing, for the first time to our knowledge, endovascular surgical treatment

Generation of non-synchronous accelerograms for evaluate the seismic bridge response, including local site amplification.

Non-synchronous seismic actions particularly affect the behaviour of infrastructures with significant longitudinal extension, as bridges, interacting with the soil at surface or below ground level. Some authors state that non synchronism may increase by a large amount the structural response. Several acceleration records relative to different points of the ground with different soil profiles at distances meaningful for bridge analyses, are not available in data banks. The objective of this work is the generation of arrays of asynchronous signals at different points in space, starting from natural accelerograms related to a given seismic event, to increase the number of the available data. The computer code GAS has been modified to use natural accelerograms. The procedure has been applied to a real case, L’Aquila main-shock, for which records in different points of the free field are known

Modal properties and seismic behaviour of buildings equipped with external dissipative pinned rocking braced frames

his paper deals with the seismic protection of building frames by means of external dissipative systems. Dampers and external framing system can be arranged in several configurations, involving different kinematic behaviours and seismic performances. This study analyses a recently-developed solution called “dissipative tower”, which exploits the rocking motion of a steel braced frame, hinged at the foundation level, for activating the dampers. This system aims at controlling both the global response and the local storey deformation of the frame, by using a reduced number of viscous dampers. A state space formulation of the dynamic problem is presented in general terms, together with the solution of the seismic problem via the modal decomposition method. A parametric study is carried out to evaluate the influence of the added damping and of the braced frame stiffness on the modal properties and seismic response of a benchmark reinforced concrete frame retrofitted with the external dissipative towers. It is shown that the addition of the towers yields a regularization and reduction of the drift demand along the building height, but it may induce significant changes, not always beneficial, in the distribution of internal actions of the frame and in the absolute storey accelerations

Phospho-TCTP as a therapeutic target of Dihydroartemisinin for aggressive breast cancer cells

Upregulation of Translationally Controlled Tumor Protein (TCTP) is associated with poorly differentiated aggressive tumors, including breast cancer, but the underlying mechanism(s) are still debated. Here, we show that in breast cancer cell lines TCTP is primarily localized in the nucleus, mostly in the phosphorylated form.The effects of Dihydroartemisinin (DHA), an anti-malaria agent that binds TCTP, were tested on breast cancer cells. DHA decreases cell proliferation and induces apoptotic cell death by targeting the phosphorylated form of TCTP. Remarkably, DHA enhances the anti-tumor effects of Doxorubicin in triple negative breast cancer cells resulting in an increased level of apoptosis. DHA also synergizes with Trastuzumab, used to treat HER2/neu positive breast cancers, to induce apoptosis of tumor cells.Finally, we present new clinical data that nuclear phospho-TCTP overexpression in primary breast cancer tissue is associated with high histological grade, increase expression of Ki-67 and with ER-negative breast cancer subtypes. Notably, phospho-TCTP expression levels increase in trastuzumab-resistant breast tumors, suggesting a possible role of phospho-TCTP as a new prognostic marker.In conclusion, the anti-tumor effect of DHA in vitro with conventional chemotherapeutics suggests a novel therapeutic strategy and identifies phospho-TCTP as a new promising target for advanced breast cancer