373 research outputs found
Pharmacognostical, physiochemical and phytochemical evaluation of leaf, stem and root of orchid Dendrobium ochreatum
The present work was aimed to carry out pharmacognosical and phytochemical evaluation of individual root, stem, and leaves of orchid “Dendrobium ochreatum.” The plant was sun dried and was grounded to fine powder using mechanical grinder followed by sieving. The fine powder was collected and subjected to different pharmacognostical studies like fluorescence analysis under uv light at different wavelength. Physiochemical parameters were also evaluated of the dried plant parts like ash values, loss on drying. Each part of plant like root, stem and leaves were separated and subjected to extraction using soxhletion using different polarity solvents i,e hexane, chloroform, ethanol in gradient elution technique. All total nine plant extracts were obtained, phytochemical screening revealed the presence of important phytoconstituents like alkaloid, glycoside, saponins etc whereas only chloroform extracts of stem exhibited the presence of steroid/phytosterol
Bio-medical waste management in different hospitals of Guwahati and its effect on environment
Biomedical waste may be defined as the waste which is produced during the diagnosis, research activities, treatment of patients, treatment of animals, production and testing of biological product and including articles as mentioned in schedule I of the Biomedical Waste (Management and handling) (second amendment) Rules 2000, as per Ministry of Environment and Forests notification. Proper treatment, handling, and disposal of biomedical wastes is essential for healthcare infection control program. There may be a high risk of infections in patients due to the poor management of biomedical waste which can lead to antibiotic resistance. It is not only the health of the patient, but also the health of persons who are associated with health care industry equally important. This article speaks about how the hospitals present in Guwahati treat their waste material and the effect of the waste in the environmen
5-Hydroxy-3-methyl-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide
In the title compound C11H13N3OS, the aromatic ring and the dihydropyrazole ring are oriented orthogonally with respect to each other, making a dihedral angle of 89.92 (9)°. An intramolecular O—H⋯S hydrogen bond occurs. In the crystal, weak N—H⋯N and N—H⋯S hydrogen bonds link the molecules into a columnar stack propagating along the b axis
Multidifferential study of identified charged hadron distributions in -tagged jets in proton-proton collisions at 13 TeV
Jet fragmentation functions are measured for the first time in proton-proton
collisions for charged pions, kaons, and protons within jets recoiling against
a boson. The charged-hadron distributions are studied longitudinally and
transversely to the jet direction for jets with transverse momentum 20 GeV and in the pseudorapidity range . The
data sample was collected with the LHCb experiment at a center-of-mass energy
of 13 TeV, corresponding to an integrated luminosity of 1.64 fb. Triple
differential distributions as a function of the hadron longitudinal momentum
fraction, hadron transverse momentum, and jet transverse momentum are also
measured for the first time. This helps constrain transverse-momentum-dependent
fragmentation functions. Differences in the shapes and magnitudes of the
measured distributions for the different hadron species provide insights into
the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any
supplementary material and additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb
public pages
Study of the decay
The decay is studied
in proton-proton collisions at a center-of-mass energy of TeV
using data corresponding to an integrated luminosity of 5
collected by the LHCb experiment. In the system, the
state observed at the BaBar and Belle experiments is
resolved into two narrower states, and ,
whose masses and widths are measured to be where the first uncertainties are statistical and the second
systematic. The results are consistent with a previous LHCb measurement using a
prompt sample. Evidence of a new
state is found with a local significance of , whose mass and width
are measured to be and , respectively. In addition, evidence of a new decay mode
is found with a significance of
. The relative branching fraction of with respect to the
decay is measured to be , where the first
uncertainty is statistical, the second systematic and the third originates from
the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb
public pages
Measurement of the ratios of branching fractions and
The ratios of branching fractions
and are measured, assuming isospin symmetry, using a
sample of proton-proton collision data corresponding to 3.0 fb of
integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The
tau lepton is identified in the decay mode
. The measured values are
and
, where the first uncertainty is
statistical and the second is systematic. The correlation between these
measurements is . Results are consistent with the current average
of these quantities and are at a combined 1.9 standard deviations from the
predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb
public pages
Photoredox/Nickel Dual Catalysis for C(sp2)-C(sp3) Cross Electrophile Coupling Reaction Using Phenols and Alcohols as the Latent Electrophile Sources
Introducing alkyl groups, particularly through innovative C(sp2)-C(sp3) bond-forming methods utilizing abundant feedstocks, holds promise for expanding chemical diversity, especially in drug discovery programs. Herein, we employed biomass-derived abundant phenols and alkyl alcohols as the coupling partners for the C(sp2)-C(sp3) cross-electrophile coupling reactions. Our innovation involved activating both the coupling partner via the same activator and designing a catalytic system that activates stronger bonds while ensuring coss-selectivity. The visible-light photoredox/nickel dual catalytic systems accommodate large substrate scope tolerating diverse functional groups. Besides, both the activation and cross-coupling reaction could be performed in one pot, and the reaction could be scaled up. Preliminary mechanistic studies involving luminescence quenching, cyclic voltammetry, radical quenching, and radical clock studies elucidated the proposed reaction mechanism
Benzyl 3-[(E)-(furan-2-yl)methylidene]-2-methyldithiocarbazate
In the title compound, C14H14N2OS 2, the furan ring exhibits rotational disorder over two orientations, with an occupancy ratio of 0.508 (7):0.492 (7). The furan and phenyl rings form dihedral angles of 8.2 (6) (major occupancy component), 14.8 (6) (minor occupancy component) and 73.65 (9)°, respectively, with the central residue (C4N2S2), indicating a twisted conformation for the molecule. The methyl group and the thione S atom are syn and the conformation about the imine bond is E. In the crystal, C - H⋯π interactions involving the phenyl ring are observed.Fil: Dey, Benu K.. University of Chittagong; BangladeshFil: Suarez, Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Inorgánica, Analítica y Química Física; ArgentinaFil: Ganguly, Biplab. University of Chittagong; BangladeshFil: Doctorovich, Fabio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Inorgánica, Analítica y Química Física; ArgentinaFil: Roy, Tapashi G.. University of Chittagong; Banglades
Autism: a Curse on Today's Society
Autism is a group of neurodevelopment disorders characterized by impaired communication, impaired social interaction and restricted, repetitive and stereotyped patterns of behaviours or interests in the first 3 years of life. It shows a strong male bias and found four times more in males than in females. According to a study in the US, in 2014, overall 1.68% of victims were reported to have Autism Spectrum Disorder (ASD), whereas the percentage was increased by 15% and 150% respectively over the year 2012 and 2000. Numerous genes have been discovered that have roles in ASD but still a good understanding of the pathophysiological process of ASD is not established. ASD costs are estimated to be approximately 450 billion. Thus, the financial burden on families is increasing. There is no effective screening tool for proper diagnosis is available. Based on Infant Toddler Checklist (ITC) and Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) some tests like ADOS-G, ADI-R, CARS etc. are used for diagnosis. There are medications to cure symptoms but no single medication for ASD. However, some therapies (like ABA- Applied Behavioural Analysis, DTT- Discrete Trial Training, and Symptomatic treatments, etc.) are there that show positive responses towards improvement from a disease state. Some crucial advancement has been achieved in the last decades. Here in the work we have focused on the diagnostic methods and treatment available for the symptoms of Autism. So, it can be said that the day is not too far away when the remedy to cut the curse of autism will be in our hands
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