3,669 research outputs found
Recommended from our members
Understanding individuals’ decisions about vaccination: a comparison between Expected Utility and Regret Theory models
Accelerator measurement of the energy spectra of neutrons emitted in the interaction of 3-GeV protons with several elements
The application of time of flight techniques for determining the shapes of the energy spectra of neutrons between 20 and 400 MeV is discussed. The neutrons are emitted at 20, 34, and 90 degrees in the bombardment of targets by 3 GeV protons. The targets used are carbon, aluminum, cobalt, and platinum with cylindrical cross section. Targets being bombarded are located in the internal circulating beam of a particle accelerator
Blood lactate clearance after maximal exercise depends on active recovery intensity
AIM: High-intensity exercise is time-limited by onset of fatigue, marked by accumulation of blood lactate. This is accentuated at maximal, all-out exercise that rapidly accumulates high blood lactate. The optimal active recovery intensity for clearing lactate after such maximal, all-out exercise remains unknown. Thus, we studied the intensity-dependence of lactate clearance during active recovery after maximal exercise.<p></p>
METHODS: We constructed a standardized maximal, all-out treadmill exercise protocol that predictably lead to voluntary exhaustion and blood lactate concentration >10 mM. Next, subjects ran series of all-out bouts that increased blood lactate concentration to 11.5±0.2 mM, followed by recovery exercises ranging 0% (passive)-100% of the lactate threshold.<p></p>
RESULTS: Repeated measurements showed faster lactate clearance during active versus passive recovery (P<0.01), and that active recovery at 60-100% of lactate threshold was more efficient for lactate clearance than lower intensity recovery (P<0.05). Active recovery at 80% of lactate threshold had the highest rate of and shortest time constant for lactate clearance (P<0.05), whereas the response during the other intensities was graded (100%=60%>40%>passive recovery, P<0.05).<p></p>
CONCLUSION: Active recovery after maximal all-out exercise clears accumulated blood lactate faster than passive recovery in an intensity-dependent manner, with maximum clearance occurring at active recovery of 80% of lactate threshold
Mapping the CMB II: the second flight of the QMAP experiment
We report the results from the second flight of QMAP, an experiment to map
the cosmic microwave background near the North Celestial Pole. We present maps
of the sky at 31 and 42 GHz as well as a measurement of the angular power
spectrum covering the l-range 40-200. Anisotropy is detected at about 20 sigma
and is in agreement with previous results at these angular scales. We also
report details of the data reduction and analysis techniques which were used
for both flights of QMAP.Comment: 4 pages, with 5 figures included. Submitted to ApJL. Window functions
and color figures are available at
http://pupgg.princeton.edu/~cmb/welcome.htm
Suppression of properties associated with malignancy in murine melanoma-melanocyte hybrid cells.
Murine and human melanoma cells differ relatively reliably from non-tumorigenic melanocytes in certain biological properties. When cultured at low pH, melanocytes tend to be pigmented and melanoma cells unpigmented. The growth of virtually all metastatic melanoma cells is inhibited by phorbol esters such as TPA (12-O-tetradecanoyl phorbol-13-acetate), which stimulate melanocyte growth. Melanocytes fail to grow in suspension culture or produce tumours when implanted in animals, while many melanoma lines can do both. Here we studied which of these properties were dominant in hybrid cells formed by fusion of drug-resistant murine B16-F10RR melanoma cells to melanocytes of the albino and brown lines, melan-c and melan-b. The albino melanocytes are unpigmented but well-differentiated, the brown melanocytes produce pale brown pigment and the melanoma cells are unpigmented under the conditions used. All hybrid colonies observed produced black pigment, except some melan-b/melanoma hybrids when growing sparsely with TPA. Thus pigmentation was generally dominant. 14/15 hybrid lines showed stimulation of proliferation by TPA, as do melanocytes. Most hybrid lines showed no or reduced capacity for growth in suspension, though some grew better in suspension when TPA was present. There was marked suppression of the tumorigenicity of the parental melanoma cells in 4/8 hybrids examined, and tumorigenicity was reduced in the others, despite considerable chromosome loss by the passage level tested. Thus most properties of the non-tumorigenic pigment cells were dominant, as often observed for other cell lineages, and providing further evidence for gene loss in the genesis of malignant melanoma
A Measurement of the Angular Power Spectrum of the CMB from l = 100 to 400
We report on a measurement of the angular spectrum of the CMB between
and made at 144 GHz from Cerro Toco in the
Chilean altiplano. When the new data are combined with previous data at 30 and
40 GHz, taken with the same instrument observing the same section of sky, we
find: 1) a rise in the angular spectrum to a maximum with K at and a fall at , thereby localizing the peak
near ; and 2) that the anisotropy at has the
spectrum of the CMB.Comment: 4 pages, 2 figures. Revised version; includes Ned Wright's postscript
fix. Accepted by ApJL. Website at http://physics.princeton.edu/~cmb
Implications of a High Angular Resolution Image of the Sunyaev-Zel'dovich Effect in RXJ1347-1145
The most X-ray luminous cluster known, RXJ1347-1145 (z=0.45), has been the
object of extensive study across the electromagnetic spectrum. We have imaged
the Sunyaev-Zel'dovich Effect (SZE) at 90 GHz (3.3 mm) in RXJ1347-1145 at 10"
resolution with the 64-pixel MUSTANG bolometer array on the Green Bank
Telescope (GBT), confirming a previously reported strong, localized enhancement
of the SZE 20" to the South-East of the center of X-ray emission. This
enhancement of the SZE has been interpreted as shock-heated (> 20 keV) gas
caused by an ongoing major (low mass-ratio) merger event. Our data support this
interpretation. We also detect a pronounced asymmetry in the projected cluster
pressure profile, with the pressure just east of the cluster core ~1.6 times
higher than just to the west. This is the highest resolution image of the SZE
made to date.Comment: 9 pages, 7 figures; accepted for publication in The Astrophysical
Journa
90GHz and 150GHz observations of the Orion M42 region. A sub-millimeter to radio analysis
We have used the new 90GHz MUSTANG camera on the Robert C. Byrd Green Bank
Telescope (GBT) to map the bright Huygens region of the star-forming region M42
with a resolution of 9" and a sensitivity of 2.8mJy/beam. 90GHz is an
interesting transition frequency, as MUSTANG detects both the free-free
emission characteristic of the HII region created by the Trapezium stars,
normally seen at lower frequencies, and thermal dust emission from the
background OMC1 molecular cloud, normally mapped at higher frequencies. We also
present similar data from the 150GHz GISMO camera taken on the IRAM telescope.
This map has 15" resolution. By combining the MUSTANG data with 1.4, 8, and
21GHz radio data from the VLA and GBT, we derive a new estimate of the emission
measure (EM) averaged electron temperature of Te = 11376K by an original method
relating free-free emission intensities at optically thin and optically thick
frequencies. Combining ISO-LWS data with our data, we derive a new estimate of
the dust temperature and spectral emissivity index within the 80" ISO-LWS beam
toward OrionKL/BN, Td = 42K and Beta=1.3. We show that both Td and Beta
decrease when going from the HII region and excited OMC1 interface to the
denser UV shielded part of OMC1 (OrionKL/BN, Orion S). With a model consisting
of only free-free and thermal dust emission we are able to fit data taken at
frequencies from 1.5GHz to 854GHz.Comment: 18 pages, 8 figures, submitted to the Astrophysical Journa
Observations of M87 and Hydra A at 90 GHz
This paper presents new observations of the AGNs M87 and Hydra A at 90 GHz
made with the MUSTANG bolometer array on the Green Bank Telescope at 8.5"
resolution. A spectral analysis is performed combining this new data and
archival VLA data on these objects at longer wavelengths. This analysis can
detect variations in spectral index and curvature expected from energy losses
in the radiating particles. M87 shows only weak evidence for steepening of the
spectrum along the jet suggesting either re-acceleration of the relativistic
particles in the jet or insufficient losses to affect the spectrum at 90 GHz.
The jets in Hydra A show strong steepening as they move from the nucleus
suggesting unbalanced losses of the higher energy relativistic particles. The
difference between these two sources may be accounted for by the different
lengths over which the jets are observable, 2 kpc for M87 and 45 kpc for Hydra
A.Comment: 11 pages, submitted to Ap
- …