The Plotline Bomber of Innisfree by Josh Massey

A review of Josh Massey\u27s The Plotline Bomber of Innisfree

An Adaptive Learning System Technology Advisor for the small business entrepreneur

In this era, businesses are fueled by IT. Today, almost all business functions are entwined with IT. IT is viewed as an extension of business functions. This in part is responsible for the competitive climate that exists among businesses to adopt IT. It is heralded as the paradigm that can revolutionize the way we conduct businesses. IT promises a realization of positive benefits to businesses that were only dreamt of yesterday. The promises of IT are numerous and alluring: competitive and strategic advantages, status, increase productivity, automation of tedious tasks, reduction of errors, the internet and its global marketplace, business leveraging, a new technological savvy consumer, and decreasing cost of hardware

Engaging Anchor Institutions in the 21st Century: An Analysis of Strategies for Sustainable Economic Growth and Health Equity

This thesis seeks to understand how anchor institutions can operate as drivers us sustainable economic development and champions of health equity. Specifically, it seeks to identify a successful outline for strategies, programs, and policies to connect economic activity and health outcomes to the success of institutions. Anchor institutions can have a powerful impact on urban development initiatives. These institutions are magnets for economic development; they encourage urban reinvention, civic pride and are hubs of attraction for people outside of the physical boundaries of the city. Rooted in their community, there is an entrenched social responsibility and civic engagement. The fate of such institutions is closely tied to the health and wellbeing of the surrounding neighborhood and city. Fostering collaboration between silos of government (planning and public health), anchor institutions, and communities can be a highly effective solution for urban economic development and community sustainability. There is serious potential for collaborative innovation by government, educational or corporate institutions, and community organizations as a successful model for urban revitalization and healthy communities. New collaborative efforts combined with innovative urban policy strategies are needed if we are to make meaningful progress in the battle to enhance city life

Containing the Kalon Kakon: The Portrayal of Women in Ancient Greek Mythology

About the Author Dessa Meehan recently finished her undergraduate degree (Magna cum Laude) at Western Washington University double majoring in History and Anthropology-Archaeology. She also minored in Geographic Information Science, Arabic and Islamic Studies, and Latin. Her research interests center around comparative women studies in classical civilizations, especially within the Roman Empire. She will continue her education in the MSt Classical Archaeology program at University of Oxford during the 2017-2018 academic year, with the eventual goal of obtaining PhD and leading archaeological excavations

Building a Case for an Adaptive Learning System Technology Advisor (ALSTA) for Business Entreprenuers During the IT Implementation Decision-Making Process

Adaptive Learning Systems [ALS] have been proposed as a new approach for analyzing, designing and implementing complex software systems [Jennings et al., 1998]. Although varied in description, these systems are characterized by behaviors that are adaptable (by selfautomation of actions) and flexible (by learning the user\u27s preferences, styles, and cognitive levels thereby offering proactive forms of interaction/support). ALS are usercentered, and have the potential to revolutionize the way users interact with computers, overcoming many of the limitations of current systems. However, the development and acceptance of agent based projects have been plagued with inconsistency and lack of grounded theoretical framework. A review of the literature also indicates that researchers have been complaining about the lack of these systems\u27 use as practical tools for real world problems [Bradshaw, 1997; Hook 1996; Jennings et al., 1998; Maes, 1994; Nwana, 1996]. This dissertation agrees and identifies a domain that can significantly benefit from this technology

Why Monitoring your Media Consumption during COVID-19 is Important

Are you spending more time consuming media (news, television, video games) than before COVID-19? Social distancing and stay-at-home orders have led to a surge in media consumption. This brief explains how too much media consumption (including the news) can affect your psychological and physiological wellbeing and provides strategies for monitoring your media consumption

Breaking Isolation: Self Care for When Coronavirus Quarantine Ends

This brief describes how prolonged periods of solitude affect our mental health and provides some strategies for how we can protect our mental and emotional health as we reengage with society

“God Sends Meat and the Devil Sends Cooks”: Meat Usage and Cuisine in Eighteenth-Century English Colonial America

American cuisines did not develop in isolation, but instead were influenced by a constant flow of information, individuals, and material culture between the colonies and the rest of the Atlantic world. These, in turn, interacted with the specific agricultural, social, and economic conditions and goals of residents in each colony. Food was a powerful symbol of identity in the English world in the eighteenth century, and printed English cookery books were widely available. What colonists ate, however, also reflected what was locally available, and resources could vary significantly between colonies. Meat usage is one aspect of cuisine that is directly observable in the archaeological record. This study employs a multidisciplinary approach to investigate the utility of printed eighteenth-century English cookery books to model and predict meat usage in the British American colonies, and to explore if or how meat usage and the larger cuisine varied from colony to colony. to do so, archaeologically-recovered faunal materials from sites in colonial Connecticut and colonial Virginia were compared against a model of meat usage constructed from a rigorous textual analysis of several popular printed cookery books and other texts available to colonists in the eighteenth century. The central aims of this research are to establish a baseline understanding of colonial American meat cuisine to allow for assessments of the ways the cuisine of the American colonists varied from their English peers, and to contextualize colonial British America cuisine in the ecological, political, and social worlds of eighteenth century Anglo-America

PENGARUH STRUKTUR MODAL, STRUKTUR KEPEMILIKAN DAN PROFITABILITAS TERHADAP NILAI PERUSAHAAN (Studi Empiris Pada Sektor Pertambangan yang Terdaftar di Bursa Efek Indonesia Periode 2012-2016)

ABSTRAK Penelitian ini bertujuan untuk mengetahui kondisi Struktur Modal yang diukur dengan Debt to Equity Ratio, Kepemilikan Institusional, Kepemilikan Manajerial dan Profitabilitas yang diukur dengan Return On Equity dan Nilai Perusahaan, serta untuk mengetahui seberapa besar pengaruh variabel Struktur Modal yang diukur dengan Debt to Equity Ratio, Kepemilikan Institusional, Kepemilikan Manajerial dan Profitabilitas yang diukur dengan Return On Equity terhadap Nilai Perusahaan pada Sektor Pertambangan di Bursa Efek Indonesia periode 2012-2016. Sampel dalam penelitian ini berjumlah 5 perusahaan. Penelitian ini menggunakan metode deskriptif dan verifikatif. Metode analisis data yang digunakan adalah analisis regresi berganda, uji hipotesis yaitu uji F dan uji t, analisis korelasi berganda, dan analisis koefisien determinasi parsial dan simultan. Sebelumnya dilakukan uji asumsi klasik untuk mengetahui ketepatan analisis regresi linier. Hasil penelitian menunjukkan bahwa Struktur Modal yang diukur dengan Debt to Equity Ratio, Kepemilikan Institusional, Kepemilikan Manajerial dan Profitabilitas yang diukur dengan Return On Equity secara simultan maupun parsial berpengaruh signifikan terhadap Nilai. Secara simultan pengaruhnya adalah 51,6% dan sisanya 48,4% dipengaruhi oleh variabel lain. Variabel yang berpengaruh dominan adalah Kepemilikan Institusional Kata Kunci : Struktur Modal (Debt to Equity Ratio), Kepemilikan Institusional, Kepemilikan Manajerial, Profitabilitas (Return On Equity), dan Nilai Perusahaa

Analysis of Plasminogen Genetic Variants in Multiple Sclerosis Patients

Dessa Sadovnick, A.; Alcina, Antonio; Fedetz, María; Matesanz, F.; Vilariño-Güell, Carles; Dessa Sadovnick, A. et. al.Multiple sclerosis (MS) is a prevalent neurological disease of complex etiology. Here, we describe the characterization of a multi-incident MS family that nominated a rare missense variant (p.G420D) in plasminogen (PLG) as a putative genetic risk factor for MS. Genotyping of PLG p.G420D (rs139071351) in 2160 MS patients, and 886 controls from Canada, identified 10 additional probands, two sporadic patients and one control with the variant. Segregation in families harboring the rs139071351 variant, identified p.G420D in 26 out of 30 family members diagnosed with MS, 14 unaffected parents, and 12 out of 30 family members not diagnosed with disease. Despite considerably reduced penetrance, linkage analysis supports cosegregation of PLG p.G420D and disease. Genotyping of PLG p.G420D in 14446 patients, and 8797 controls from Canada, France, Spain, Germany, Belgium, and Austria failed to identify significant association with disease (P = 0.117), despite an overall higher prevalence in patients (OR = 1.32; 95% CI = 0.93–1.87). To assess whether additional rare variants have an effect on MS risk, we sequenced PLG in 293 probands, and genotyped all rare variants in cases and controls. This analysis identified nine rare missense variants, and although three of them were exclusively observed in MS patients, segregation does not support pathogenicity. PLG is a plausible biological candidate for MS owing to its involvement in immune system response, blood-brain barrier permeability, and myelin degradation. Moreover, components of its activation cascade have been shown to present increased activity or expression in MS patients compared to controls; further studies are needed to clarify whether PLG is involved in MS susceptibility.We also thank Généthon, L’Association Française contre les Myopathies (AFM), la Fondation pour l’Aide à la Recherche sur la Sclérose en Plaques (ARSEP), and the Biological Resources Centre (BRC) of The French Multiple Sclerosis Genetics Group (CRB-REFGENSEP). This research was undertaken thanks to funding from the Canada Research Chair [950-228408] and Canada Excellence Research Chair programs [214444], Canadian Institutes of Health Research [MOP-137051], Vancouver Coastal Health Research Institute, the Milan & Maureen Ilich Foundation [11-32095000], and the Vancouver Foundation [ADV14-1597]. Replication studies received funding from the program “Investissements d’avenir” ANR-10-IAIHU-06. Fondo de Investigación Sanitaria (FIS)-Instituto de Salud Carlos III (ISCIII)-Fondos Europeos de Desarrollo Regional (FEDER), Unión Europea [grant numbers P12/00555, PI13/01527, PI13/01466 and PI13/0879 to F.M., A.A. and G.I.] and Junta de Andalucía -FEDER [grant number CTS2704 to F.M.]. B.D. is a Clinical Investigator of the Research Foundation Flanders (FWO-Vlaanderen). A.G. and B.D. are supported by the Research Fund KU Leuven (OT/11/087 and CREA/14/023) and the Research Foundation Flanders (G073415N). A.L.T. reports personal fees from Biogen Idec, Chugai, Medimmune, Teva Innovation, and EMD Serono, and grants and personal fees from Genzyme Sanofi and Roche.Peer reviewe