102 research outputs found
Structure of 2-Methyl-5,6,7-triphenyl-6,7-dihydropyrazolo[2,3-\u3cem\u3ea\u3c/em\u3e]pyrimidine
C25H21N3, Mr = 363.46, monoclinic, P21/n, a = 9.245 (2), b = 23.502 (5), c = 9.340 (2) Å, β= 103.50(3)°, V=1973.3(2) Å3, Z=4, Dx= 1.220 (2) g cm-3, λ (Mo Kα )= 0.71069 Å, μ = 0.068 cm-1, F(000) = 768, T= 292 K, R = 0.091 for 1442 unique observed reflections. The dihydropyrimidine ring adopts a distorted sofa conformation. The aryl substituents on the saturated C atoms have an axial orientation
Unusual in Water Multicomponent Reaction of 3-Amino-5-methylpyrazole, Acetylacetone and Aldehyde
Multicomponent reaction of 3-amino-5-methylpyrazole, aliphatic aldehyde (paraformaldehyde or acetaldehyde) and acetylacetone in water by conventional heating, microwave or ultrasound activation undergoes on molar amounts of reagents 2:1:2, respectively, leads bis(2,5,7-trimethylpyrazolo[1,5-a]pyrimidin-6-yl)-substituted methane or to corresponding 1,1-bis-substituted ethane
N-[4-(Dimethylamino)benzylidene]-4H-1,2,4-triazol-4-amine
The title compound, C11H13N5, is a Schiff base synthesized by the reaction of 4-amino-4H-1,2,4-triazole and 4-(dimethylamino)benzaldehyde. The dihedral angle between the benzene and triazole rings is 43.09 (11)°. The crystal structure displays weak C—H⋯N interactions
3-Nitro-1H-1,2,4-triazole
The asymmetric unit of the title compound, C2H2N4O2, contains two crystallographically independent molecules in which the triazole rings are essentially planar, with maximum deviations of 0.003 (1) Å in both molecules. The dihedral angle between the two 1H-1,2,4-triazole rings is 56.58 (5)°. In the crystal, molecules are linked via intermolecular N—H⋯N and C—H⋯O hydrogen bonds, forming a supramolecular chain along the b axis
Aminoazole-Based Diversity-Oriented Synthesis of Heterocycles
The comprehensive review contains the analysis of literature data concerning reactions of heterocyclization of aminoazoles and demonstrates the application of these types of transformations in diversity-oriented synthesis. The review is oriented to wide range of chemists working in the field of organic synthesis and both experimental and theoretical studies of nitrogen-containing heterocycles
Scintillation neutron detector on the basis of boron-containing plastics
Main parameters are presented for plastic scintillators containing boron. These scintillators were obtained by the block
polymerization method of polystyrene with luminescent dopants and allyldodecaborane. Sample dimensions: diameter
25 mm, height 25 mm. Parameters studied included light output, sensitivity to neutrons and time characteristics.У роботі представлені основні параметри пластмасових сцинтиляторів, які містять бор. Ці сцинтилятори одержані за
допомогою методу блочної полімеризації полістиролу з домішками, що випромінюють люмінесценцію та алилдодекабораном. Розміри зразків: Ø25х25 мм. Досліджені світловий вихід, чутливість до нейтронів та компоненти висвічування.В работе представлены основные параметры пластмассовых сцинтилляторов, содержащих бор. Эти сцинтилляторы
получены методом блочной полимеризации полистирола с люминесцирующими добавками и аллилдодекабораном. Размеры образцов: диаметр 25 мм и высота 25 мм. Исследованы световой выход, чувствительность к нейтронам и времен-
ные характеристики
Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction
Substituted 1H-pyrazolo[3,4-b]pyridine-4- and 1H-pyrazolo[3,4-b]pyridine-6-carboxamides have been synthetized through a Doebner–Ugi multicomponent reaction sequence in a convergent and versatile manner using diversity generation strategies: combination of two multicomponent reactions and conditions-based divergence strategy. The target products contain as pharmacophores pyrazolopyridine and peptidomimetic moieties with four points of diversity introduced from readily available starting materials including scaffold diversity. A small focused compound library of 23 Ugi products was created and screened for antibacterial activity
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