1,096 research outputs found

    Silicon spin diffusion transistor: materials, physics and device characteristics

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    The realisation that eaveryday electronics has ignored the spin of the carrier in favour of its charge is the foundation of the field of spintronics. Starting with simple two-terminal devices based on GMR and tunnel magnetoresistance, the technology has advanced to consider three-terminal devices that aim to combine spin sensitivity with a high current gain and a large current output. These devices require both efficient spin injection and semiconductor fabrication. In this paper, a discussion is presented of the design, operation and characteristics of the only spin transistor that has yielded a current gain greater than one in combination with reasonable output current

    In-vivo pan/tilt endoscope with integrated light source

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    Endoscopic imaging is still dominated by the paradigm of pushing long sticks into small openings. This approach has a number of limitations for minimal access surgery, such as narrow angle imaging, limited workspace, counter-intuitive motions and additional incisions for the endoscpic instruments. Our intent is to go beyond this paradigm, and remotize sensors and effectors directly into the body cavity. To this end, we have developed a prototype of a novel insertable pan/tilt endoscopic camera with an integrated light source. The package has a size of 110 mm in length and 10 mm in diameter and can be inserted into the abdomen through a standard trocar and then anchored onto the abdominal wall, leaving the incision port open for access. The camera package contains three parts: an imaging module, an illumination module, and a pan/tilt motion platform. The imaging module includes a lens and CCD imaging sensor. The illumination module attaches to the imaging module and has an array of LED light sources. The pan/tilt platform provides the imaging module with pan of 120 degrees and tilt motion of 90 degrees using small servo motors. A fixing mechanism is designed to hold the device in the cavity. A standard joy stick can be used to control the motion of the camera in a natural way. The design allows for multiple camera packages to be inserted through a single incision as well

    Supernatants derived from chemotherapy-treated cancer cell lines can modify angiogenesis

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    BACKGROUND: There is evidence that tumours produce substances such as cytokines and microvesicular bodies bearing bioactive molecules, which support the carcinogenic process. Furthermore, chemotherapy has also been shown to modify these exudates and in doing so, neutralise their tumourigenic influence. METHODS: In the current study, we have investigated the effect of chemotherapy agents on modifying the cytokine profile and microvesicular cargo of supernatants derived from cancer cell lines. In addition, we have explored the effect of these tumour-derived supernatants on angiogenesis, and how chemotherapy can alter the supernatants rendering them less pro-angiogenic. RESULTS: Herein, we show that supernatants contain a rich cocktail of cytokines, a number of which are potent modulators of angiogenesis. They also contain microvesicular bodies containing RNA transcripts that code for proteins involved in transcription, immune modulation and angiogenesis. These supernatants altered intracellular signalling molecules in endothelial cells and significantly enhanced their tubulogenic character; however, this was severely compromised when supernatants from tumours treated with chemotherapy was used instead. CONCLUSION: This study suggests tumour exudates and bioactive material from tumours can influence cellular functions, and that treatment with some chemotherapy can serve to negate these pro-tumourigenic processes

    Learning to Develop a Culturally Relevant Approach to 21st Century Writing Instruction

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    In a position statement, Beliefs about the Teaching of Writing (2004), NCTE outlines eleven broad principles to serve as a guide for teaching language arts. Among the key ideas in this document is the call for language arts teacher educators to consider how literacy courses can create opportunities for pre-service teachers to account for the multifaceted and multimodal world of literacy with students in K-12 settings. The purpose of this qualitative case study is to learn from the experience of one pre-service teacher during his language arts methods course. Drawing on a subset of data from two, our research team focused on the following questions for this report: 1. How did the participant in this study come to draw upon his own process of writing and composing digital texts to support elementary students\u27 writing development? 2. How did the participant take up the theoretical concepts presented in his language arts methods course during the field-based experience? 3. How did the participant enact tenets of CRP in a 21st century classroom

    On The Low-Frequency Vibrational Modes of C60_{60}

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    The vibrational spectrum of C60_{60} is compared to the spectrum of a classical isotropic elastic spherical shell. We show correlations between the low frequency modes of C60_{60} and those of the spherical shell. We find the spherical model gives the approximate frequency ordering for the low frequency modes. We estimate a Poisson ratio of σ≈0.30\sigma\approx 0.30 and a transverse speed of sound of vs≈1800v_s\approx 1800 m/s for the equivalent elastic shell. We also find that ω(M1)/ω(M0)=32\omega({\rm M_1})/\omega({\rm M_0})=\sqrt{3\over 2} for the shell modes M0{\rm M_0} and M1{\rm M_1}, independent of elastic constants. We find that this ratio compares favorably with an experimental value of 1.17.Comment: 11 pages, 3 figures in Postscript, uses REVTEX, to be published in Chem. Phys. Let

    NASA Sea Ice Validation Program for the Defense Meteorological Satellite Program Special Sensor Microwave Imager

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    The history of the program is described along with the SSM/I sensor, including its calibration and geolocation correction procedures used by NASA, SSM/I data flow, and the NASA program to distribute polar gridded SSM/I radiances and sea ice concentrations (SIC) on CD-ROMs. Following a discussion of the NASA algorithm used to convert SSM/I radiances to SICs, results of 95 SSM/I-MSS Landsat IC comparisons for regions in both the Arctic and the Antarctic are presented. The Landsat comparisons show that the overall algorithm accuracy under winter conditions is 7 pct. on average with 4 pct. negative bias. Next, high resolution active and passive microwave image mosaics from coordinated NASA and Navy aircraft underflights over regions of the Beaufort and Chukchi seas in March 1988 were used to show that the algorithm multiyear IC accuracy is 11 pct. on average with a positive bias of 12 pct. Ice edge crossings of the Bering Sea by the NASA DC-8 aircraft were used to show that the SSM/I 15 pct. ice concentration contour corresponds best to the location of the initial bands at the ice edge. Finally, a summary of results and recommendations for improving the SIC retrievals from spaceborne radiometers are provided

    Composition Operators and Endomorphisms

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    If bb is an inner function, then composition with bb induces an endomorphism, β\beta, of L∞(T)L^\infty(\mathbb{T}) that leaves H∞(T)H^\infty(\mathbb{T}) invariant. We investigate the structure of the endomorphisms of B(L2(T))B(L^2(\mathbb{T})) and B(H2(T))B(H^2(\mathbb{T})) that implement β\beta through the representations of L∞(T)L^\infty(\mathbb{T}) and H∞(T)H^\infty(\mathbb{T}) in terms of multiplication operators on L2(T)L^2(\mathbb{T}) and H2(T)H^2(\mathbb{T}). Our analysis, which is based on work of R. Rochberg and J. McDonald, will wind its way through the theory of composition operators on spaces of analytic functions to recent work on Cuntz families of isometries and Hilbert C∗C^*-modules
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