Measurement of Neutrino-Nucleon Neutral Current Elastic Scattering in MiniBooNE

Using a high-statistics sample of neutral current elastic neutrino interactions, MiniBooNE measured the flux-averaged neutral current elastic differential cross-section on mineral oil ($CH_2$). Using the latter, a $\chi^2$ test of MC with different values of the axial vector mass has been performed. Also, a possibility of using a sample of neutral current elastic proton-enriched events above Cherenkov threshold to measure the ratio $\nu p\to \nu p /\nu N\to \nu N$ is discussed. This ratio is sensitive to the strange quark contribution to the nucleon spin, $\Delta s$.Comment: 6 pages, 4 figures, 2 tables, Proceedings of the 6th International Workshop on Neutrino-Nucleus Interactions in the Few-GeV Region (NuInt09

Neutrino-nucleus neutral current elastic interactions measurement in MiniBooNE

The MiniBooNE experiment at the Fermi National Accelerator Laboratory (Fermilab) was designed to search for {nu}{sub {mu}} {yields} {nu}{sub e} neutrino oscillations at {Delta}m{sup 2} {approx} 1 eV{sup 2} using an intense neutrino flux with an average energy E{sub {nu}} {approx} 700 MeV. From 2002 to 2009 MiniBooNE has accumulated more than 1.0 x 10{sup 21} protons on target (POT) in both neutrino and antineutrino modes. MiniBooNE provides a perfect platform for detailed measurements of exclusive and semiinclusive neutrino cross-sections, for which MiniBooNE has the largest samples of events up to date, such as neutral current elastic (NCE), neutral current {pi}{sup 0}, charged current quasi-elastic (CCQE), charged current {pi}{sup +}, and other channels. These measured cross-sections, in turn, allow to improve the knowledge of nucleon structure. This thesis is devoted to the study of NCE interactions. Neutrino-nucleus neutral current elastic scattering ({nu}N {yields} {nu}N) accounts for about 18% of all neutrino interactions in MiniBooNE. Using a high-statistics, high purity sample of NCE interactions in MiniBooNE, the flux-averaged NCE differential cross-section has been measured and is being reported here. Further study of the NCE cross-section allowed for probing the structure of nuclei. The main interest in the NCE cross-section is that it may be sensitive to the strange quark contribution to the nucleon spin, {Delta}s, this however requires a separation of NCE proton ({nu}p {yields} {nu}p) from NCE neutron ({nu}n {yields} {nu}n) events, which in general is a challenging task. MiniBooNE uses a Cherenkov detector, which imposes restrictions on the measured nucleon kinematic variables, mainly due to the impossibility to reconstruct the nucleon direction below the Cherenkov threshold. However, at kinetic energies above this threshold MiniBooNE is able to identify NCE proton events that do not experience final state interactions (FSI). These events were used for the {Delta}s measurement. In this thesis MiniBooNE reports the NCE (n+p) cross-section, the measurement of the axial mass, M{sub A}, and the {Delta}s parameter from the NCE data

NOvA experiment in light of large

NOvA is an off-axis long baseline neutrino experiment searching for νμ → νe oscillations using an upgraded NuMI neutrino beam from Fermilab, Batavia, IL. The main physics goal is a measurement of the CP violation and establishing the neutrino masses hierarchy. A large 14 kton Far detector, comprised of liquid scintillator contained in extruded PVC cells, will also provide an opportunity for other non-accelerator physics searches. While civil construction at the far detector is underway, a smaller prototype near detector has been assembled at Fermilab and is being studied

Neutrino-nucleus neutral current elastic interactions measurement in MiniBooNE

The MiniBooNE experiment at the Fermi National Accelerator Laboratory (Fermilab) was designed to search for electron to muon neutrino oscillations at Delta m^2~1 eV^2 using an intense neutrino flux with an average energy of about 700 MeV. From 2002 to 2009 MiniBooNE has accumulated more than 1.0x10^{21} protons on target (POT) in both neutrino and antineutrino modes. MiniBooNE provides a perfect platform for detailed measurements of exclusive and semiinclusive neutrino cross-sections, for which MiniBooNE has the largest samples of events up to date, such as neutral current elastic (NCE), neutral current pi^0, charged current quasi-elastic (CCQE), charged current pi^+, and other channels. These measured cross-sections, in turn, allow to improve the knowledge of nucleon structure. This thesis is devoted to the study of NCE interactions. Neutrino-nucleus neutral current elastic scattering accounts for about 18% of all neutrino interactions in MiniBooNE. Using a high-statistics, high purity sample of NCE interactions in MiniBooNE, the flux-averaged NCE differential cross-section has been measured and is being reported here. Further study of the NCE cross-section allowed for probing the structure of nuclei. The main interest in the NCE cross-section is that it may be sensitive to the strange quark contribution to the nucleon spin, $Delta s$, this however requires a separation of NCE proton from NCE neutron events, which in general is a challenging task. MiniBooNE uses a Cherenkov detector, which imposes restrictions on the measured nucleon kinematic variables, mainly due to the impossibility to reconstruct the nucleon direction below the Cherenkov threshold. However, at kinetic energies above this threshold MiniBooNE is able to identify NCE proton events that do not experience final state interactions. These events were used for the $Delta s$ measurement. In this thesis MiniBooNE reports the NCE (n+p) cross-section, the measurement of the axial mass, $M_A$, and the $Delta s$ parameter from the NCE data. (Published By University of Alabama Libraries

Inhibitors of the RBD-ACE-2 Found among a Wide Range of Dyes by the Immunoassay Method

Angiotensin-converting enzyme 2 (ACE2), the functional receptor of SARS-CoV-2, plays a crucial role in the pathogenesis of COVID-19. ACE2 targeting holds the promise for preventing and inhibiting SARS-CoV-2 infection. In this work, we describe the development and use of a test system based on competitive ELISA for the primary screening of potential antiviral compounds. We studied the activity of the library of dyes of different groups. Several dyes (ortho-cresolphthalein, eosin (free acid), eosin (Na salt)) that inhibited the interaction of ACE2 with the spike proteins of SARS-CoV-2 have been identified among the candidates. A potential antiviral drug, methylene blue, did not show activity in our study. We believe that our results can help in the further search for inhibitors of interaction between the coronavirus spike protein and ACE2 receptor

Alignment of solid targets under extreme tight focus conditions generated by an ellipsoidal plasma mirror

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