32,404 research outputs found
Ab-initio investigation of the covalent bond energies in the metallic covalent superconductor MgB2 and in AlB2
The contributions of the covalent bond energies of various atom pairs to the
cohesive energy of MgB2 and AlB2 are analysed with a variant of our recently
developed energy-partitioning scheme for the density-functional total energy.
The covalent bond energies are strongest for the intralayer B-B pairs. In
contrast to the general belief, there is also a considerable covalent bonding
between the layers, mediated by the metal atom. The bond energies between the
various atom pairs are analysed in terms of orbital- and energy-resolved
contributions.Comment: 6 pages, 1 figure, 2 tables, submitted to PR
Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum.
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain incompletely characterized. Previous studies have focused on characterizing these progenitors in the postnatal and adult subventricular zone and on analyzing the cellular and physiological properties of these cells in white and gray matter regions in the forebrain. In the present study, we examine the types of neural progeny generated by NG2 progenitors in the cerebellum by employing genetic fate mapping techniques using inducible Cre-Lox systems in vivo with two different mouse lines, the Plp-Cre-ER(T2)/Rosa26-EYFP and Olig2-Cre-ER(T2)/Rosa26-EYFP double-transgenic mice. Our data indicate that Olig2/Plp-positive NG2 cells display multipotential properties, primarily give rise to oligodendroglia but, surprisingly, also generate Bergmann glia, which are specialized glial cells in the cerebellum. The NG2+ cells also give rise to astrocytes, but not neurons. In addition, we show that glutamate signaling is involved in distinct NG2+ cell-fate/differentiation pathways and plays a role in the normal development of Bergmann glia. We also show an increase of cerebellar oligodendroglial lineage cells in response to hypoxic-ischemic injury, but the ability of NG2+ cells to give rise to Bergmann glia and astrocytes remains unchanged. Overall, our study reveals a novel Bergmann glia fate of Olig2/Plp-positive NG2 progenitors, demonstrates the differentiation of these progenitors into various functional glial cell types, and provides significant insights into the fate and function of Olig2/Plp-positive progenitor cells in health and disease
Effective g-factor in Majorana Wires
We use the effective g-factor of subgap states, g*, in hybrid InAs nanowires
with an epitaxial Al shell to investigate how the superconducting density of
states is distributed between the semiconductor core and the metallic shell. We
find a step-like reduction of g* and improved hard gap with reduced carrier
density in the nanowire, controlled by gate voltage. These observations are
relevant for Majorana devices, which require tunable carrier density and g*
exceeding the g-factor of the proximitizing superconductor. Additionally, we
observe the closing and reopening of a gap in the subgap spectrum coincident
with the appearance of a zero-bias conductance peak
Nonlocality of Majorana modes in hybrid nanowires
Spatial separation of Majorana zero modes distinguishes trivial from topological midgap states and is key to topological protection in quantum computing applications. Although signatures of Majorana zero modes in tunneling spectroscopy have been reported in numerous studies, a quantitative measure of the degree of separation, or nonlocality, of the emergent zero modes has not been reported. Here, we present results of an experimental study of nonlocality of emergent zero modes in superconductor-semiconductor hybrid nanowire devices. The approach takes advantage of recent theory showing that nonlocality can be measured from splitting due to hybridization of the zero mode in resonance with a quantum dot state at one end of the nanowire. From these splittings as well as anticrossing of the dot states, measured for even and odd occupied quantum dot states, we extract both the degree of nonlocality of the emergent zero mode, as well as the spin canting angles of the nonlocal zero mode. Depending on the device measured, we obtain either a moderate degree of nonlocality, suggesting a partially separated Andreev subgap state, or a highly nonlocal state consistent with a well-developed Majorana modeThis research was supported by Microsoft, the Danish National Research Foundation, the European Commission, and the Spanish Ministry of Economy and Competitiveness through Grants No. FIS2015-65706-P, No. FIS2015-64654-P, and No. FIS2016-80434-P (AEI/FEDER, EU), the Ramón y Cajal programme Grant No. RYC-2011-09345, and the MarÃa de Maeztu Programme for Units of Excellence in R&D (Grant No. MDM-2014-0377). C.M.M. acknowledges support from the Villum Foundation. M.-T.D. acknowledges support from State Key Laboratory of High Performance Computing, Chin
A Killing Disease Epidemic Among Displaced Sudanese Population Identified as Visceral Leishmaniasis.
A fatal disease epidemic affected the Bentiu area in southern Sudan and led to a mass migration of the Nuer tribe searching for treatment. The initially available information revealed a high mortality rate due to a possible occurrence of tuberculosis, malaria, enteric fever or visceral leishmaniasis (VL). Serological screening of 53 of the most severely affected patients in an enzyme-linked immunosorbent assay (ELISA) or an improved direct agglutination test (DAT) revealed positivity for VL. In 39 of those patients, diagnosis was confirmed by identification of Leishmania donovani amastigotes in lymph node or bone-marrow aspirates. In a total of 2714 patients observed, 1195 (44.0%) had clinical symptoms suggesting VL: DAT positive titers (1:3200-greater than or equal to 1:12800) were obtained in 654 (24.1%), of whom 325 were confirmed parasitologically. Forty-two VL cases died before or during treatment, giving a mortality rate of 6.4%. Among the intercurrent infections diagnosed in the VL population (654), respiratory involvements (31.7%) and malaria (10.7%) were most prevalent. With the exception of four (0.6%), all other VL patients (509) responded readily to sodium stibogluconate. The factors initiating the outbreak are discussed. Malnutrition and nomadic movements to potential VL endemic areas appeared to be the most important. HIV infection as a possible predisposition seemed remote considering the clinical and epidemiological similarity to VL occurring in East Africa, adequate humoral response in DAT, and immediate positive response to specific anti-Leishmania chemotherapy
Analytical Solution of Electron Spin Decoherence Through Hyperfine Interaction in a Quantum Dot
We analytically solve the {\it Non-Markovian} single electron spin dynamics
due to hyperfine interaction with surrounding nuclei in a quantum dot. We use
the equation-of-motion method assisted with a large field expansion, and find
that virtual nuclear spin flip-flops mediated by the electron contribute
significantly to a complete decoherence of transverse electron spin correlation
function. Our results show that a 90% nuclear polarization can enhance the
electron spin time by almost two orders of magnitude. In the long time
limit, the electron spin correlation function has a non-exponential
decay in the presence of both polarized and unpolarized nuclei.Comment: 4 pages, 3 figure
Characteristic velocities of stripped-envelope core-collapse supernova cores
The velocity of the inner ejecta of stripped-envelope core-collapse
supernovae (CC-SNe) is studied by means of an analysis of their nebular
spectra. Stripped-envelope CC-SNe are the result of the explosion of bare cores
of massive stars ( M), and their late-time spectra are
typically dominated by a strong [O {\sc i}] 6300, 6363 emission
line produced by the innermost, slow-moving ejecta which are not visible at
earlier times as they are located below the photosphere. A characteristic
velocity of the inner ejecta is obtained for a sample of 56 stripped-envelope
CC-SNe of different spectral types (IIb, Ib, Ic) using direct measurements of
the line width as well as spectral fitting. For most SNe, this value shows a
small scatter around 4500 km s. Observations ( days) of
stripped-envelope CC-SNe have revealed a subclass of very energetic SNe, termed
broad-lined SNe (BL-SNe) or hypernovae, which are characterised by broad
absorption lines in the early-time spectra, indicative of outer ejecta moving
at very high velocity (). SNe identified as BL in the early phase
show large variations of core velocities at late phases, with some having much
higher and some having similar velocities with respect to regular CC-SNe. This
might indicate asphericity of the inner ejecta of BL-SNe, a possibility we
investigate using synthetic three-dimensional nebular spectra.Comment: 14 pages, 10 figures, MNRAS accepte
Bounded Representations of Interval and Proper Interval Graphs
Klavik et al. [arXiv:1207.6960] recently introduced a generalization of
recognition called the bounded representation problem which we study for the
classes of interval and proper interval graphs. The input gives a graph G and
in addition for each vertex v two intervals L_v and R_v called bounds. We ask
whether there exists a bounded representation in which each interval I_v has
its left endpoint in L_v and its right endpoint in R_v. We show that the
problem can be solved in linear time for interval graphs and in quadratic time
for proper interval graphs.
Robert's Theorem states that the classes of proper interval graphs and unit
interval graphs are equal. Surprisingly the bounded representation problem is
polynomially solvable for proper interval graphs and NP-complete for unit
interval graphs [Klav\'{\i}k et al., arxiv:1207.6960]. So unless P = NP, the
proper and unit interval representations behave very differently.
The bounded representation problem belongs to a wider class of restricted
representation problems. These problems are generalizations of the
well-understood recognition problem, and they ask whether there exists a
representation of G satisfying some additional constraints. The bounded
representation problems generalize many of these problems
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