Fokal megalensefalinin eşlik ettiği tuberoskleroz kompleksinin manyetik rezonans görüntüleme bulguları: Olgu sunumu

WOS: 000372008100017Hemimegalencephaly (HME) is a rare cortical developmental anomaly that can be defined as abnormal neural and glial proliferation localized to all or part of a cerebral hemisphere. Tuberous sclerosis complex (TSC) is an autosomal dominant, multisystem disease that most frequently involves the central nervous system, skin, heart, kidneys, and eyes. Herein, we report the magnetic resonance imaging findings of a rare case of focal megalencephaly with TSC.Hemimegalensefali serebral hemisferin tamamının veya bir kısmının etkilendiği anormal nöral ve glial proliferasyon ile tanımlanabilen ender bir kortikal gelişimsel anomalidir. Tuberoskleroz kompleksi (TSK) otozomal dominant geçişli, başta santral sinir sistemi olmak üzere kalp, böbrek, göz ve cildi tutan multisistem hastalığıdır. Çalışmamızda ender olarak görülen fokal megalensefalinin eşlik ettiği TSK olgusunun manyetik rezonans görüntüleme bulgularını sunmayı amaçladık

Bronchoscopic findings in children with congenital heart disease

WOS: 000451979401455Introduction: The aim of this study was evaluation of broncoscopic findings in children with congenital heart disease(CHD). Method: Bronchoscopy was performed in 37 patients with CHD who were followed between October 2012–December 2014 in our hospital. The data obtained from these patients were evaluated retrospectively. Results: Twenty-one of the patients were males and 16 were females, median ages 12.5 mo (1-36m). Twenty-seven patients (72.9 %) were operated for congenital heart disease. Twelve of the patients had pulmonary hypertension. Bronchoscopy was performed because of extubation failure, atelectasis, recurrent or persistant pneumonia, stridor and persistant cough; 17,7,7,4 and 2, respectively. Laryngomalacia, tracheomalacia, bronchomalacia, tracheal stenosis, airway branch anomalies, granulation tissue formation and pulsatile airway pressure was determined in flexible bronchoscopy, 13,12,8,4,17,7 and 10, respectively. Twenty-seven of the patients were followed with mechanical ventilation(MV). MV duration before and after bronchoscopy was median 30 and 12 days, respectively. Tracheostomy was performed in 15 cases. After bronchoscopy five of these patients were removed from tracheostomy. Eleven out of the patients had positive culture in bronkoalveolar lavage. Patients were discharged with room air, tracheostomy with room air, only with supplemental oxygen, tracheostomy with supplemental oxygen; 19(51.3%), 6(16.2%), 1(2.7%),1(2.7%), respectively. One patient was following intubated with ventilatory support. Nine patients died. Conclusions: Airway anomalies were more frequently encountered in patients with congenital heart disease

Incidence and severity of retinopathy of prematurity in Turkey

Background: The purpose of this study was to estimate the current incidence of retinopathy of prematurity (ROP) and the need for treatment in preterm infants in Turkey. Methods: The study included preterm infants who had been screened for ROP between 2011 and 2013 in 49 neonatal intensive care units. Infants with birth weight (BW) ≤1500 g or ≤32 weeks' gestational age and those with BW >1500 g or >32 weeks' GA with an unstable clinical course were included. The incidence of any ROP or severe ROP and treatment modalities were determined. Results: The study population included 15 745 preterm infants: 11 803 (75%) with GA ≤32 weeks, and 3942 (25%) with GA >32 weeks. Overall, 30% were found to have any stage of ROP, and 5% had severe ROP. Severe ROP was diagnosed in 8.2% of infants with BW ≤1500 g and 0.6% of infants with BW >1500 g. Of all infants diagnosed with ROP, 16.5% needed laser photocoagulation, and 20 patients born at >32 weeks' GA required this treatment modality. Vitroretinal surgery was performed in 28 infants with severe ROP: 23 with GA ≤28 weeks and 5 with GA 29-32 weeks. Conclusions: The findings of our study have the important implication that more mature babies are at risk of severe ROP requiring treatment. An effective programme for detecting and treating ROP should be established in Turkey