50 research outputs found

    Is there a relationship between thyroid hormone levels and suicide attempt in adolescents?

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    Background: Thoughts about suicide are quite common in adolescent. While such thoughts can be caused by many reasons, the most wellknown of these are mood disorders. There are studies related to coexistence of thyroid pathologies and mood disorders in adult. Objectives: In this study, we aimed to investigate the difference of thyroid hormone levels in between adolescents with suicide attempt history and normal population. Methods: The study was prospective and was designed as a case-control study. Demographic characteristics of the patients were obtained and Serum fT3, fT4 and TSH levels were examined. Results: 222 cases were included in the study, including 101 cases and 121 controls. As for TSH levels, the mean serum levels of the whole group was 1.96 ± 1.08 mU/L, while the mean serum levels of the control group was 2.33 ± 1.5 mU/L and the mean serum levels of the case group was 0.50 ± 0.3 mU/L which revealed that the mean serum levels of the case group was significantly lower (p<0.01). Conclusion: It was found that serum TSH levels were significantly lower in case group than control group and the individuals with subclinical hyperthyroidism had more suicide attempts than the ones in control group

    Voice characteristics associated with polycystic ovary syndrome

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    Objectives/HypothesisTo test the assumption that voice is changed in polycystic ovary syndrome (PCOS) and identify changes that occur

    RELATIONSHIPS BETWEEN CUSP POINTS IN THE EXTENDED MODULAR GROUP AND FIBONACCI NUMBERS

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    WOS: 000488872100009Cusp (parabolic) points in the extended modular group (Gamma) over bar are basically the images of infinity under the group elements. This implies that the cusp points of (Gamma) over bar are just rational numbers and the set of cusp points is Q(infinity) = Q boolean OR {infinity} .The Farey graph F is the graph whose set of vertices is Q(infinity) and whose edges join each pair of Farey neighbours. Each rational number x has an integer continued fraction expansion (ICF) x = [b(1), ..., b(n)]. We get a path from infinity to x in F as for each ICF. in this study, we investigate relationships between Fibonacci numbers, Farey graph, extended modular group and ICF. Also, we give a computer program that computes the geodesics, block forms and matrix represantations

    Does Nissen Fundoplication Improve Deglutition In Children?

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    A prospective study was performed to evaluate the effect of Nissen fundoplication (NF) on deglutition in children. Children who underwent NF between 2011-2015 were evaluated for demographic features, clinical findings, diagnostic methods for gastroesophageal reflux (GER) and indications for NF. Penetration aspiration scale (PAS), functional oral intake scale (FOIS) and esophageal functions were evaluated by videoflouroscopy (VFS). Preoperative and postoperative VFS findings were compared to evaluate the effect of NF on clinical findings and deglutition. Twenty-three children with a mean age of 5.08 +/- 3.7 years were included. Female to male ratio was 15:8. Recurrent respiratory infections (RTI) (n:14, 60.8%), swallowing dysfunction (n:13, 56.5%) and vomiting (n:10, 43.4%) were the most common symptoms. Preoperatively GER was diagnosed with barium swallowing study (BSS) contrast graphs (n:20, 87%) and with 24-hour esophageal pH monitorization (n:8, 34.8%). In 39.1% of patients, medical treatment for GER was used with a mean duration of 8 +/- 5.8 months. Indications for NF were swallowing dysfunction (n:18, 78%), GER complications (n:6, 26%), associated anatomical problems (n:4, 17.3%) and unresponsiveness to medical treatment (n:3, 13%). Postoperative barium swallowing study and 24-hour esophageal pH monitorization showed no GER after NF in 95% of patients. Number of RTI were significantly decreased after NF (preoperative vs postoperative infection rate 4.21 vs 1.6 respectively, p0.05). FOIS were significantly improved after NF (p<0.05). VFS findings showed that penetration and aspiration were significantly decreased after NF and children had less RTI. Although, esophageal motility evaluated by VFS did not changed after NF, functional oral intake significantly improved in children.WoSScopu

    Evaluation of the Relationship between Insulin Resistance and Selenoprotein P in Patients with Polycystic Ovary Syndrome

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    Polikistik Over Sendromlu Hastalarda İnsülin Direnci ve Selenoprotein P İlişkisinin DeğerlendirilmesiAyşenur Özderya1, İbrahim Yılmaz2, Şevin Demir3, Şule Temizkan1, Mehmet Sargın4, Mehmet Ali Ustaoğlu2, Kadriye Aydın11Sağlık Bilimleri Üniversitesi, Kartal Dr. Lütfi Kırdar Eğitim Ve Araştırma Hastanesi, Endokrinoloji Ve Metabolizma Hastalıkları Bölümü,i̇stanbul, Türkiye2Sağlık Bilimleri Üniversitesi, Kartal Dr. Lütfi Kırdar Eğitim Ve Araştırma Hastanesi, İç Hastalıkları Kliniği, İstanbul, Türkiye3Sağlık Bilimleri Üniversitesi, Kartal Dr Lütfi Kırdar Eğitim ve Araştırma Hastanesi, Aile Hekimliği Kliniği, İstanbul, Türkiye4Medeniyet Üniversitesi Tıp Fakültesi, Aile Hekimliği Kliniği, İstanbul, TürkiyeGİRİŞ ve AMAÇ: Polikistik over sendromu (PKOS) doğurganlık çağındaki kadınlarda en sık görülen ve insülin direnci (IR) ile karakterize bir bozukluktur. Selenoprotein P(SeP) de, insülin direnciyle ilişkili bir hepatokindir. Bu çalışmada PKOS’da SeP düzeylerini belirlemeyi ve IR ile ilişkisini araştırmayı amaçladık.&nbsp;YÖNTEM ve GEREÇLER: Çalışmada 27 hastayla yaş ve vücut kitle indeksi (VKI) eşleştirilmiş 27 sağlıklı kontrolün demografik özellikleri, antropometrik ölçümleri ve biyokimyasal parametreleri değerlendirildi. IR ve serbest androjen indeksi (FAI) hesaplandı. SeP ile biyokimyasal ve antropometrik parametrelerin korelasyonu yapıldı.BULGULAR: Hasta ve kontroller arasında açlık insülini ve HOMA-IR anlamlı farklıyken (her iki p&lt;0.05), SeP düzeyleri benzerdi (sırasıyla, 1.05±0.7ng/mL ve 1.61±1.9ng/mL, p=0.7). Her iki grupta da SeP ile HOMA-IR arasında korelasyon saptanmadı. PCOS grubunda SeP ile bel çevresi arasında negatif korelasyon mevcutken (p=0.03, r=-0.485), kontrol grubunda izlenmedi. Kontrol grubunda ise SeP ile VKI ve yağ yüzdesi arasında negatif korelasyon mevcutken (sırasıyla r=-0.506, p=0.007 ve r=-0.643, p=0.024), PCOS grubunda izlenmedi. Ayrıca hastalarda testosteron ile SeP arasında anlamlı pozitif korelasyon saptandı (r=0,456, p=0,017).&nbsp;TARTIŞMA ve SONUÇ: Hasta ve kontroller arasında SeP düzeyleri benzer bulundu ve PKOS’da SeP ile IR arasında bir ilişki saptanmadı. Ancak PKOS'da SeP’nin bel çevresi ve testosteron ile korelasyonu olası bir metabolik ilişkiyi akla getirmektedir.&nbsp;Anahtar Kelimeler:&nbsp;İnsülin direnci, polikistik over sendromu, selenoprotein P, vücut kitle indeksi, vücut yağ yüzdesi.</p
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