Handwriting style classification

This paper describes an independent handwriting style classifier that has been designed to select the best recognizer for a given style of writing. For this purpose a definition of handwriting legibility has been defined and a method implemented that can predict this legibility. The technique consists of two phases. In the feature-extraction phase, a set of 36 features is extracted from the image contour. In the classification phase, two nonparametric classification techniques are applied to the extracted features in order to compare their effectiveness in classifying words into legible, illegible, and middle classes. In the first method, a multiple discriminant analysis (MDA) is used to transform the space of extracted features (36 dimensions) into an optimal discriminant space for a nearest mean based classifier. In the second method, a probabilistic neural network (PNN) based on the Bayes strategy and nonparametric estimation of probability density function is used. The experimental results show that the PNN method gives superior classification results when compared with the MDA method. For the legible, illegible, and middle handwriting the method provides 86.5% (legible/illegible), 65.5% (legible/middle), and 90.5% (middle/illegible) correct classification for two classes. For the three-class legibility classification the rate of correct classification is 67.33% using a PNN classifier

Relationship between serum visfatin and vascular inflammation markers level in beta thalassemia major patients

Background: Understanding the possible role of visfatin in the pathogenesis of beta-thalassemia major (BTM) and its relationship with markers of endothelial function could help us to provide more effective therapeutic approaches for treatment of patients with BTM and its related complications. The aim of current study was to compare serum level of visfatin between patients with BTM and control group and determine its correlation with markers of endothelial function, intracellular adhesion molecule (ICAM) and vascular adhesion molecule (VCAM). Methods: In this case-control study, patients with BTM receiving regular blood transfusion aged 10-20 years and a group of healthy subjects were enrolled. Selected subjects examined clinically and venous blood samples obtained for visfatin, ICAM, VCAM, cholesterol, triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol and ferritin measurements. Mean (standard deviation) of studied laboratory measurements compared in two studied groups and the relation between visfatin and ICAM, VCAM, ferrittin, body mass index determined. Results: In this study 31 patients with BTM and 30 healthy controls studied. Mean of visfatin was significantly higher in patients with BTM than control group (133.9 ± 60.1 vs. 43.3 ± 27.9, P < 0.001). Conclusions: The higher level of visfatin among patients with BTM indicated the possible inflammatory role of this adipocytokine in BTM. It seems that for understanding the underlying mechanisms and its relation with vascular inflammatory markers and endothelial function further studies with larger sample size is needed. © 2014, Isfahan University of Medical Sciences(IUMS). All rights reserved

EFFECTS OF RELAXATION AND CITALOPRAM ON SEVERITY AND FREQUENCY OF THE SYMPTOMS OF IRRITABLE BOWEL SYNDROME WITH DIARRHEA PREDOMINANCE

Objectives: Irritable bowel syndrome (IBS) is the most prevalent functional bowel disorder which is characterized by chronic abdominal pain and altered bowel habit in the absence of any organic disease. This study examined the effects of ``relaxation and citalopram'' in comparison to ``citalopram'' alone on alleviating the symptoms of IBS patients with diarrhea predominance. Methodology: This study was a randomized clinical trial which included 64 IBS patients. The patients were selected according to Rome-III criteria, and were divided into two groups. Bowel Symptoms Severity and Frequency Scale (BSS-FS) was used for evaluation of the patients' symptoms. Data was analyzed using analysis of covariance (ANCOVA). Results: There were significant differences in the severity and frequency of IBS symptoms between two groups after the study period regarding BSS-FS (P 0.05). Conclusion: Relaxation in addition to citalopram in IBS patients with diarrhea predominance can decrease the severity and frequency of symptoms. However, stopping this treatment may lead to recurrence of the symptoms

Optimization of expression, purification and handling anti bacteria feature protein of bovine neutrophil B-defensing BNBD2

زمینه و هدف: دیفنسین‎ها یکی از بزرگ‎ترین خانواده‎ی پپتید‎های ضد میکروب می‎باشند که به واسطه‎ی فعالیت بر علیه باکتری‎ها، قارچ‎ها و بسیاری از ویروس‎ها به عنوان آنتی‎بیوتیک‎های نسل جدید منفعت بسیاری دارند. هدف از این مطالعه بهینه سازی بیان، تخلیص و بررسی خاصیت ضد میکروبی پروتئین بتا دیفنسین 2 نوتروفیل‎های گاو (BNBD2) بوده است. روش بررسی: در این مطالعه‎ی تجربی-آزمایشگاهی باکتری اشرشیاکلی B‏L21(DE3) حامل وکتور pET-32a(+) که ژن BNBD2 در آن همسانه سازی شده بود جهت مطالعات مورد استفاده قرار گرفت. بیان پروتئین BNBD2 با تغییر در پارامترهای دانسیته‎ی سلولی، دمای رشد، مدت زمان القاء با استفاده از سیستم الکتروفورز عمودی (SDS-PAGE) و تست برادفورد به صورت کمی و کیفی بررسی گردید. مراحل تخلیص پروتئین نوترکیب با کمک روش شیمیایی شکافت در جایگاه فرمیک اسید و عبور از سانتریکون و اثر ضد باکتری پروتئین تخلیص شده بر چند نمونه‎ی باکتریایی گرم مثبت و گرم منفی مورد بررسی قرار گرفت. یافته ها: با استفاده از محیط کشت Luria–Bertani، شروع القاء در جذب نوری 8/0 در طول موج 600 نانومتر، غلظت یک میلی مولار ماده‎ی القاء کننده‎ی IPTG، دمای رشد 30 درجه و مدت زمان 4 ساعت پس از القاء بیشترین میزان بیان پروتئین به دست آمد. پروتئین نوترکیب با استفاده از شکافت در جایگاه فرمیک اسید و عبور از سانتریکون تخلیص گردید. نتایج آزمایش وسترن بلاتینگ نیز نشان داد که پروتئین نوترکیب به طور اختصاصی به آنتی‎بادی mouse anti-(His)6 peroxidase متصل می‎گردد. تشکیل هاله‎ی عدم رشد در محیط‎های کشت مولر هینتون آگار حاوی کشت سطحی باکتری های مورد آزمایش خاصیت ضد باکتری این پروتئین را نشان داد. نتیجه گیری: با توجه به خاصیت ضد میکروبی پروتئین BNBD2و امکان بیان پروتئین در باکتری E. coli می توان به تولید انبوه این پروتئین نوترکیب اقدام نمود

The effect of occupational therapy on positive and negative symptoms in schizophrenic patients

Background and aim: Poor social, self-care, and vocational functioning are criteria for a diagnosis of schizophrenia in most diagnostic systems. Consequently, improving the social behaviors of persons with schizophrenia has been a key target of psychiatric rehabilitation. The occupational therapy is a non organic therapeutic that causes elevated self stem, foppishness and strengthening of occupational behaviour. The aim of this survey is the effect of occupational therapy on the positive and negative symptom’s of schizophrenic patients with bear out their symptoms. Methods: This survey is an experimental study that, positive and negative symptom’s of schizophrenic patients assessed with scale for the assessment of positive and negative symptoms. Then the samples consisted of schizophrenic patients divided randomly into case (30) and control (30) groups. Occupational therapy was performed in case group within a period 20 hours in week for 6 months, then patiants assessed repeatly with SAPS.SANS. Quantative analysis of data was undertaken by using paired and dependent t students tesats and Willcoxon test . Results: Results demonestrated the mean of the total score of negative symptom 72.5±19.5 and posetive symptom 112±32.57. Also occupational therapy effected on the posetive and negative symptom’s of schizophrenic patiants. In posetive symptom occupational therapy effected on the hallusination and bizzare behaviour (P<0.001), for all noeffected on dellusions and thought. In negative symptom occupational therapy effected on the apathy and involition, attention disorders, anhedonia and thought disorders (P<0.001), for all noeffected on inappropiate affect. Conclusion: The occupational therapy is a non organic therapuitic that causes elevated self steem, foppishness and strengthening of occupational behaviou

Identification of chemical compounds of <em>Nardostachys Jatamansi </em>essence available in Iran

Introduction: With regard to using drugs with plant origin and with the aim of suitable use of these types of drugs and preventing them to be abused, it is necessary to determine the standards of these plants. The aim of the present study was to identify and study chemical compounds of Nardostachys Jatamansi essence in Iran and define monograph of this plant for the Iranian plant pharmacopeia. Methods: In an experimental study the Nardostachys Jatamansi specimen was prepared from the market in Iran. The essence of the plant was prepared by the hydro-distillation in Clevenger apparatus. Essence was obtained as a greenish yellow oil layer with the 0.07 yield. The essence compounds were identified quantitatively by Gas Chromatography-Mass Spectroscopy (GC/MS) method. Results: Totally, 29 compounds were identified in Nardostachys Jatamansi essence. The retention indexes (RI) were only similar with overall standard values in two compounds like mesitylene and P-cymene. In this line the RI values about three compounds of valerenic acid, palmitic acid, and valerenyl isovalerate were determined significantly higher than standard values of RI. Conclusion: The essence prepared from the Nardostachys Jatamansi plant in Iran was different in terms of some compounds and components including valerenic acid, palmitic acid, and valerenyl isovalerate and so it is necessary to identify and register quality and quantity characteristics of compounds available in this plat in the Iranian medicinal plants pharmacopeia.</p

Gabriel Triangulations and Angle-Monotone Graphs: Local Routing and Recognition

A geometric graph is angle-monotone if every pair of vertices has a path between them that---after some rotation---is $x$- and $y$-monotone. Angle-monotone graphs are $\sqrt 2$-spanners and they are increasing-chord graphs. Dehkordi, Frati, and Gudmundsson introduced angle-monotone graphs in 2014 and proved that Gabriel triangulations are angle-monotone graphs. We give a polynomial time algorithm to recognize angle-monotone geometric graphs. We prove that every point set has a plane geometric graph that is generalized angle-monotone---specifically, we prove that the half-$\theta_6$-graph is generalized angle-monotone. We give a local routing algorithm for Gabriel triangulations that finds a path from any vertex $s$ to any vertex $t$ whose length is within $1 + \sqrt 2$ times the Euclidean distance from $s$ to $t$. Finally, we prove some lower bounds and limits on local routing algorithms on Gabriel triangulations.Comment: Appears in the Proceedings of the 24th International Symposium on Graph Drawing and Network Visualization (GD 2016

The relationship between body image and marital adjustment in infertile women

Introduction: Body image is one of the most important issues in women's mental health and due to its relationship with physical, cognitive and emotional aspects of women’s life; it can predict their healthy or unhealthy behaviors. According to some research reports, women’s negative or positive body image can affect their marital relationships. Considering the impact of infertility on both body image and marital adjustment and the lack of evidence regarding the relationship of these two variables in infertility, this study aimed to investigate the relationship of body image with marital adjustment in infertile women in 2010 in Mashhad. Methods: This correlational study was carried out on 130 infertile women referred to Montaserie Infertility Research Center in Mashhad who were selected through convenient sampling. Research tools were consisted of valid and reliable demographic questionnaire including personal and infertility-related information, modified Younesi Body Image Questionnaire and Spanier marital adjustment scale (DAS) which were completed by subjects. Data analysis was carried out by SPSS software (version 15/5) using t-tests, one way ANOVA, and Spearman and Pearson correlation test. Results: 93/1% of women reported positive body image and 76/9% had high marital adjustment. There was a direct correlation between the overall score of body image with marital adjustment (P<0/001). There was also a direct correlation between the scores of body image subscales including body in loneliness (P= 0/001), real body (P=0/014), public image of body (P=0/016), spouse image of body (P<0/001) and spouse family image of body (P<0/001) with marital adjustment. However, this relationship was not observed between the subscale of ideal body and marital adjustment. Conclusion: The presence of a direct correlation between body image and marital adjustment could guide developing educational or counseling programs particularly for infertile women who suffer from marital disputes. Keywords: Body image, Marital adjustment, Infertilit