Utjecaji dodatka kulture kvasaca (Saccharomyces cerevisiae) u obroke anatolijskih vodenih bivolica na sastav mlijeka i broj somatskih stanica

This study was carried out to determine the effect of Saccharomyces cerevisiae (SC) addition to dry matter intake, milk yield, milk composition and somatic cell count in Anatolian water buffalo diets (AWB). The SC-treated groups (n = 5 buffalo cow/group) received 30.0 g of SC per buffalo cow per day. Compared to the control group, the SC-treated group consumed more total dry matter (P<0.05; 14.27 vs. 13.50 kg/day) and produced more milk/day (P<0.01; 7.13 vs. 6.22 kg/day). Dietary yeast inclusion significantly increased alfalfa dry matter intake during a 28-day lactation period (P<0.01; 10.41 vs. 9.81 kg/day) compared with the control diet. Yeast application significantly reduced the somatic cell count (SCC) in milk (P<0.05; 3.33 and 1.08 SCC (log 10/mL) for control and SC-treated groups, respectively). The fat (58.40 and 59.00 g/kg), non-fat solids (120.00 and 122.80 g/kg), protein (46.40 and 46.26. g/kg) and lactose components of milk (37.72 and 38.90 g/kg) were similar for both groups. The response of the AWB to supplemental yeast addition improved forage intake and daily milk production but did not affect milk composition. In conclusion; it has been thought that farmers with AWB can benefit from the use of yeast cultures in early lactation diets.Istraživanje je provedeno kako bi se utvrdio utjecaj dodatka Saccharomyces cerevisiae (SC) na unos suhe tvari obroka, količinu i sastav mlijeka te broj somatskih stanica u mlijeku anatolijskih vodenih bivolica (AWB). Pokusna skupina SC (n = 5 krava/ skupini) dobila je 30,0 g SC po kravi na dan. U usporedbi s kontrolnom skupinom, SC- skupina konzumirala je više ukupne suhe tvari (P<0,05; 14,27 : 13,50 kg/dan), i proizvela veću dnevnu količinu mlijeka (P<0,01; 7,13 : 6,22 kg/dan). Uključivanje konzumnog kvasca u obrok značajno je povećalo unos suhe tvari lucerne tijekom 28-dnevnog razdoblja laktacije (P<0,01; 10,41 : 9,81 kg/dan) u usporedbi s kontrolnom skupinom. Primjena kvasca značajno je smanjila broj somatskih stanica (SCC) u mlijeku (P<0,05; kontrolna 3,33 : pokusna SC 1,08 SCC (log10/mL). Količine masti (58,40 i 59,00 g/kg), bezmasne suhe tvari (120,00 i 122,80 g/kg), proteina (46,40 i 46,26 g/kg) i laktoze (37,72 i 38,90 g/kg) bile su slične za obje skupine. Odgovor AWB na dopunu obroka kvascem bilo je povećanje unosa krme i dnevne proizvodnje mlijeka, ali nije utjecalo na sastav mlijeka. Stoga, proizvođači mlijeka koji drže AWB mogu imati koristi od korištenja kulture kvasaca SC u obrocima tijekom rane laktacije

A Prospective Study of Adolescents' Peer Support: Gender Differences and the Influence of Parental Relationships

This longitudinal study investigates parent and child predictors of adolescents' perceived social support from peers. Adolescents (285) and their parents filled out surveys when students were 11 and 15 years of age. Parent reports of their own social support and child reports of parental support to them, depression, and self-esteem were used as predictors of adolescents' peer social support. Path analyses revealed functional dissimilarity in the predictive model, for boys and girls. For boys and girls, the amount of spousal support parents' reported impacted the amount of parent to child support that children reported. For boys, this relationship impacted their perceptions of peer support indirectly through depression. However, for girls, parents' own supportive relationships directly impacted both their self-esteem and depression, above and beyond parent to child support, which then impacted girls' peer social support.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45288/1/10964_2004_Article_229992.pd

JOURNAL OF BUON

Purpose: To compare the efficacy and adverse effect profiles of the first-line treatment of patients with KRAS wild type metastatic colorectal cancer (CRC) in Turkey who were treated based on regimens including bevacizumab, cetuximab and panitumumab. Methods: This retrospective multicenter observational study involved a total of 238 patients who received chemotherapy in combination with either bevacizumab or cetuximab or panitumumab as first-line therapy for KRAS wild-type metastatic colorectal cancer. Patients with full medical records having pathological diagnosis of CRC adenocarcinoma were included in the study. The demographic, laboratory, histopathological and clinical characteristics of the patients were determined, and three groups were compared based on the study variables. Results: The mean age of the entire sample (n=238) was 58 +/- 11 years, 64% of which were male. The most frequent tumor localization was the rectum (37%) and G2 was the most common tumor grade (59.7%). About 63% of the patients had metastatic disease at diagnosis, with the most common site of metastasis being lung (14.7%) and liver (52.5%). Overall survival (OS) was 63.9%, while 1-, 3- and 5-year survival rates were 91.7, 56.6 and 36.9%, respectively. The expected mean survival was 49.1 months (95% CI, 42.9-55.3). The 1-, 3- and 5-year progression-free survival (PFS) rates following first-line treatment were 65.3, 26.1 and 5.6%, respectively, while disease free survival (DFS) in patients without metastasis at diagnosis was 68.5%. An analysis carried out disregarding which treatment the patients received (FOLFOX or FOLFIRI) revealed that a panitumumab-containing combination resulted in poorer prognosis compared to bevacizumab or cetuximab-containing combination (p <0.001). With regard to the adverse effect profile, the most common adverse effects were neuropathy and neutropenia in patients receiving FOLFOX-bevacizumab; neutropenia and perforation in patients receiving FOLFIRI-bevacizumab; rash and pustular infection in patients receiving FOLFIRI-cetuximab; and diarrhea in patients who received FOLFIRI-panitumumab combination. Conclusion: is the first multicenter study performed in Turkey evaluating the response to treatment and adverse effects in patients with KRAS wild-type metastatic colorectal cancer

The prevalence and impacts heavy menstrual bleeding on anemia, fatigue and quality of life in women of reproductive age

Objectives: To investigate the prevalence and impacts of heavy menstrual bleeding (HMB) on anemia, fatigue, and the quality of life (QoL) in women of reproductive age. Methods: This study was conducted among 306 women of reproductive age who presented at the internal medicine outpatient departments of the training and research hospital of a university. The data of the study were collected by the “Data collection form”, “SF-36 Quality of Life Scale (SF-36 QoLS)” and “Brief Fatigue Inventory (BFI)”. Results: The prevalence of HMB in women of reproductive age was 37.9%. The ferritin level and physical functions were found to decrease significantly as the duration of menstruation increased (p<0.05). Besides, a positive but very weak relationship was found between the menstruation duration and the subdimensions of the global BFI and the general health perception subscale of the SF-36 QoLS (p<0.05). Conclusion: It was determined that HMB is common and has negative effects on anemia, fatigue and some subdimensions of the QoL. Regular screening for HMB that may not be expressed by many women may therefore be useful in preventing and resolving the health problems that it will cause. © 2019, Professional Medical Publications. All rights reserved

Effect of ground fenugreek seeds (<i>Trigonella foenum-graecum</i>) on feed consumption and milk performance in Anatolian water buffaloes

In this study, the effects of a diet including fenugreek (<i>Trigonella foenum-graecum</i>) seed on feed consumption and milk performance were examined. A total of 24 buffaloes were randomly divided into two groups (12 animals each). The diet containing ground fenugreek seed (GFS) improved total dry matter (13.17–14.00 kg day⁻¹) (<i>P</i> &lt; 0.05) and daily concentrated feed consumption (2.90–3.81 kg day⁻¹) (<i>P</i> &lt; 0.01) and significantly increased milk production (7.34–8.01 kg day⁻¹) (<i>P</i> &lt; 0.01) in Anatolian water buffaloes (AWBs). In future work, the use of other herbs in AWB may be investigated

classification tree method

Most current statistical strategies for determining risk factors for hypertension (HT) among certain populations have proved inconclusive. In this study, the classification tree method, which is more practical and easy to understand than other statistical methods, was used to determine the risk for HT among outpatients in a clinic in Denizli province, western Turkey, between January 2002 and July 2004. The effects of 14 risk factors (body mass index, waist-to-hip ratio, age, serum total cholesterol, serum triglycerides, sex, HT in first-degree relatives, diabetes mellitus, smoking, stress factors, alcohol consumption, dyslipidemia in first-degree relatives, dyslipidemia [previously diagnosed], and saturated fat consumption) on HT were evaluated in this population. in all, 1761 adults at the outpatient clinic were recruited for lipid and HT measurements. The classification tree method revealed 7 main risk factors (body mass index, waist-to-hip ratio, sex, serum triglycerides, serum total cholesterol, HT in first-degree relatives, and saturated fat consumption) for HT. The findings of the present study suggest that the classification tree is a valuable statistical method for evaluating multiple risk factors for HT.C1 Pamukkale Univ, Dept Biostat, TR-20070 Denizli, Turkey.Pamukkale Univ, Dept Endocrinol & Metab, TR-20070 Denizli, Turkey.Pamukkale Univ, Dept Internal Med, TR-20070 Denizli, Turkey.Pamukkale Univ, Dept Biochem, TR-20070 Denizli, Turkey.Private Ctr, Dept Internal Med, Izmir, Turkey.Zonguldak Karaelmas Univ, Dept Biostat, Zonguldak, Turkey