This study was carried out to determine the effect of Saccharomyces cerevisiae (SC) addition to dry matter intake, milk yield, milk composition and somatic cell count in Anatolian water buffalo diets (AWB). The SC-treated groups (n = 5 buffalo cow/group) received 30.0 g of SC per buffalo cow per day. Compared to the control group, the SC-treated group consumed more total dry matter (P<0.05; 14.27 vs. 13.50 kg/day) and produced more milk/day (P<0.01; 7.13 vs. 6.22 kg/day). Dietary yeast inclusion significantly increased alfalfa dry matter intake during a 28-day lactation period (P<0.01; 10.41 vs. 9.81 kg/day) compared with the control diet. Yeast application significantly reduced the somatic cell count (SCC) in milk (P<0.05; 3.33 and 1.08 SCC (log 10/mL) for control and SC-treated groups, respectively). The fat (58.40 and 59.00 g/kg), non-fat solids (120.00 and 122.80 g/kg), protein (46.40 and 46.26. g/kg) and lactose components of milk (37.72 and 38.90 g/kg) were similar for both groups. The response of the AWB to supplemental yeast addition improved forage intake and daily milk production but did not affect milk composition. In conclusion; it has been thought that farmers with AWB can benefit from the use of yeast cultures in early lactation diets.Istraživanje je provedeno kako bi se utvrdio utjecaj dodatka Saccharomyces cerevisiae (SC) na unos suhe tvari obroka, količinu i sastav mlijeka te broj somatskih stanica u mlijeku anatolijskih vodenih bivolica (AWB). Pokusna skupina SC (n = 5 krava/ skupini) dobila je 30,0 g SC po kravi na dan. U usporedbi s kontrolnom skupinom, SC- skupina konzumirala je više ukupne suhe tvari (P<0,05; 14,27 : 13,50 kg/dan), i proizvela veću dnevnu količinu mlijeka (P<0,01; 7,13 : 6,22 kg/dan). Uključivanje konzumnog kvasca u obrok značajno je povećalo unos suhe tvari lucerne tijekom 28-dnevnog razdoblja laktacije (P<0,01; 10,41 : 9,81 kg/dan) u usporedbi s kontrolnom skupinom. Primjena kvasca značajno je smanjila broj somatskih stanica (SCC) u mlijeku (P<0,05; kontrolna 3,33 : pokusna SC 1,08 SCC (log10/mL). Količine masti (58,40 i 59,00 g/kg), bezmasne suhe tvari (120,00 i 122,80 g/kg), proteina (46,40 i 46,26 g/kg) i laktoze (37,72 i 38,90 g/kg) bile su slične za obje skupine. Odgovor AWB na dopunu obroka kvascem bilo je povećanje unosa krme i dnevne proizvodnje mlijeka, ali nije utjecalo na sastav mlijeka. Stoga, proizvođači mlijeka koji drže AWB mogu imati koristi od korištenja kulture kvasaca SC u obrocima tijekom rane laktacije
