Contract Production in the Selected Building Company

Import 05/08/2014Předmětem diplomové práce je zakázková výroba ve vybraném stavebním podniku. Tato práce se skládá ze tří částí. První část je věnována teorii plánů a rozpočtů, jež jsou pro stavební firmu stěžejní. Následující kapitola je zaměřena na náklady a kalkulace, na jejich členění a na metody sestavení. V poslední části jsou analyzovány vybrané zakázky a navržena možná doporučení.The subject of this thesis is contract production in the selected building company. This work consists of the three parts. The first part is devoted to the theory of plans and budgets. These budgets are fundamental for building company. The following chapter is focused on the costs and calculations for the subdivision and the setting method together. In the final part are analyzed the selected contracts and possible recommendations.117 - Katedra účetnictvívelmi dobř

Internal Accounting Rules in the Selected Account Unit

Import 11/07/2012Předmětem této práce jsou vnitřní účetní předpisy ve vybrané účetní jednotce. Jedná se zejména o odpisový plán, rezervy, zásoby a inventarizaci majetku a závazků. Ke každému předpisu je uveden jeho teoretický význam. Hlavním cílem práce je vytvoření kvalitních směrnic pro potřeby účetní jednotky.Subject of this thesis are the internal accounting rules in the selected account unit. In particular, schedule of depreciation, reserves, supplies and inventory of assets and liabilities. Each regulation is that its theoretical significance. The main goal is to create quality guidelines for the needs of the unit.117 - Katedra účetnictvívelmi dobř

Human Multipotent Mesenchymal Stromal Cells in the Treatment of Postoperative Temporal Bone Defect: An Animal Model

International audienceCanal wall down mastoidectomy is one of the most effective treatments for cholesteatoma. However, it results in anatomical changes in the external and middle ear with a negative impact on the patient's quality of life. To provide complete closure of the mastoid cavity and normalize the anatomy of the middle and external ear, we used human multipotent mesenchymal stromal cells (hMSCs), GMP grade, in a guinea pig model. A method for preparing a biomaterial composed of hMSCs, hydroxyapatite, and tissue glue was developed. Animals from the treated group were implanted with biomaterial composed of hydroxyapatite and hMSCs, while animals in the control group received hydroxyapatite alone. When compared to controls, the group implanted with hMSCs showed a significantly higher ratio of new bone formation (p = 0.00174), as well as a significantly higher volume percentage of new immature bone (p = 0.00166). Our results proved a beneficial effect of hMSCs on temporal bone formation and provided a promising tool to improve the quality of life of patients after canal wall down mastoidectomy by hMSC implantation