Defect in lung growth Comparative study of three diagnostic criteria.

Traduction anglaise de l'article Arch Pediatr. 2004 Jun;11(6):515-7 Référence pubmed : 15158815A systematic analysis was made of the autopsies of 74 newborns and fetuses (49 pathological cases and 25 controls) to detect defects in lung growth. In each case lung/body (L/B) weight ratio was calculated, and radial alveolar (RA) count and histological assessment were performed. The L/B ratio is of diagnostic value when lower than 0.012 but not when there is intercurrent disease. RA count is low in lung hypoplasia but is not an entirely reliable diagnostic criterion since it change throughout pregnancy and the earlier the gestational age the wider the range of variation. Histological assessment showed an abnormally high number of bronchi and bronchi in distal location with in some cases delayed differentiation of distal airways. If any one of the above three critera fails to determine lung hypoplasia the other two can be used to arrive at diagnosis

Recherche de tiers corps pour la distillation azéotropique discontinue

La distillation batch est une technique de séparation importante dans l’industrie chimique, notamment pour les mélanges azéotropiques. Une procédure d’exploration systématique de la faisabilité de procédés de distillation batch, pouvant nécessiter l’ajout d’un tiers corps a été élaborée au sein du logiciel RegSolExpert®. L’illustration consiste à séparer le mélange eau – acétonitrile formant un azéotrope à température de bulle minimal

Is There a Relationship between Ovarian Epithelial Dysplasia and Infertility?

Aim. Ovarian epithelial dysplasia was initially described in material from prophylactic oophorectomies performed in patients at genetic risk of ovarian cancer. Similar histopathological abnormalities have been revealed after ovulation stimulation. Since infertility is also a risk factor for ovarian neoplasia, the aim of this study was to study the relationship between infertility and ovarian dysplasia. Methods. We blindly reviewed 127 histopathological slides of adnexectomies or ovarian cystectomies according to three groups—an exposed group to ovulation induction (n = 30), an infertile group without stimulation (n = 35), and a spontaneously fertile control group (n = 62)—in order to design an eleven histopathological criteria scoring system. Results. The ovarian dysplasia score was significantly higher in exposed group whereas dysplasia score was low in infertile and control groups (resp., 8.21 in exposed group, 3.69 for infertile patients, and 3.62 for the controls). In the subgroup with refractory infertility there was a trend towards a more severe dysplasia score (8.53 in ovulation induction group and 5.1 in infertile group). Conclusion. These results raise questions as to the responsibility of drugs used to induce ovulation and/or infertility itself in the genesis of ovarian epithelial dysplasia

Reiter's syndrome following shigella flexneri 2a

Shigella flexneri 2a was isolated from a patient with Reiter's syndrome (RS) following a family outbreak of traveler's diarrhea. Among 3 members at risk, only the patient was positive for HLA-B27. Data from 3 similar families support the hypothesis that susceptibility to RS is genetically transmitted. It is urged that every effort be made to culture and subtype Shigella and other enteric pathogens in RS following diarrhea. Concurrently, the patient had hepatitis, interpreted as a parallel enteric infection.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/37731/1/1780200117_ftp.pd

Glutamine supplementation

Intravenous glutamine supplementation is standard care when parenteral nutrition is given for critical illness. There are data of a reduced mortality when glutamine supplementation is given. In addition, standard commercial products for parenteral nutrition do not contain any glutamine due to glutamine instability in aqueous solutions. For the majority of critical ill patients who are fed enterally, the available evidence is insufficient to recommend glutamine supplementation. Standard formulation of enteral nutrition contains some glutamine: 2-4 g/L. However, this dose is insufficient to normalize glutamine plasma concentration

Etude et mise en oeuvre d'un environnement d'exécution pour architecture hétérogène reconfigurable

Today, embedded systems have taken a leading role in our world. Whether for communication, travel, work or entertainment, their use is preponderant. Together, research and industry efforts are constantly developing various parts that make up these systems: processor, FPGA, memory, operating system.From an architectural point of view, the contribution of a generalist architecture coupled with a reconfigurable architecture positions SoC FPGA as popular targets for use in embedded systems. However, their implementation's complexity makes their adoption difficult. The abstraction of low-level layers seems to be an investigation's axis that would tend to reverse this trend. The use of an operating system seems suitable at first glance because they deliver an ecosystem of drivers and services for access to hardware resources, native scheduling capacities and libraries for security. However, this solution brings constraints and lead to evaluate other approaches.This manuscript evaluates the ability of a high-level language, Lua, to provide an execution environment in such a case that the implementation does not provide operating system. It gives, through an ecosystem named Lynq, the necessary building blocks for the management and allocation of resources present on the SoC FPGA as well as a method for isolation between applications. Besides the adoption of this execution environment, our work explores the capacity of generalist architectures such as CPUs to become specialized when implemented on a FPGA. This is done through a contribution allowing the generation of a RISC-V CPU and its associated microcode.Aujourd'hui, les systèmes embarqués ont pris une part hégémonique dans notre monde. Leurs utilisation est prépondérante, que ce soit pour communiquer, se déplacer, travailler ou se divertir. Des efforts dans le domaine de la recherche et de l'industrie n'ont de cesse de faire évoluer les parties qui composent ces systèmes dont le processeur, le FPGA, la mémoire et le système d'exploitation.D'un point de vue architectural, l'apport d'une architecture généraliste couplée à une architecture reconfigurable positionne le SoC FPGA comme une cible préférentielle pour une utilisation dans les systèmes embarqués. Leurs adoption est cependant difficile du fait de leur complexité d'implémentation. L'abstraction des couches de bas niveau semble un axe d'investigation qui tend à inverser cette tendance. Au premier abord, l'utilisation d'un système d'exploitation paraît idoine. En effet, il possède l'écosystème de drivers et services disponibles pour l'accès aux ressources matérielles, la capacité d'ordonnancement natif ainsi que des bibliothèques pour la sécurité. Toutefois, cette solution engendre des contraintes qui poussent à évaluer d'autres approches. Ce manuscrit évalue la capacité d'un langage de haut niveau tel que Lua à fournir un environnement d'exécution dans le cas d'une implémentation sans système d'exploitation.À travers un écosystème nommé Lynq, cet environnement d'exécution procure les briques nécessaires à la gestion et l'allocation des ressources présentes sur le SoC FPGA, ainsi qu'une méthode proposant une isolation entre applicatifs.La capacité des architectures généralistes que sont les CPUs à devenir spécialisés lorsqu'ils sont implémentés sur un FPGA a été exploré par la suite. Ceci au travers d'une contribution permettant la génération d'un CPU RISC-V ainsi que son microcode associé

Study and implementation of an execution environment for heterogeneous reconfigurable architecture

Aujourd'hui, les systèmes embarqués ont pris une part hégémonique dans notre monde. Leurs utilisation est prépondérante, que ce soit pour communiquer, se déplacer, travailler ou se divertir. Des efforts dans le domaine de la recherche et de l'industrie n'ont de cesse de faire évoluer les parties qui composent ces systèmes dont le processeur, le FPGA, la mémoire et le système d'exploitation.D'un point de vue architectural, l'apport d'une architecture généraliste couplée à une architecture reconfigurable positionne le SoC FPGA comme une cible préférentielle pour une utilisation dans les systèmes embarqués. Leurs adoption est cependant difficile du fait de leur complexité d'implémentation. L'abstraction des couches de bas niveau semble un axe d'investigation qui tend à inverser cette tendance. Au premier abord, l'utilisation d'un système d'exploitation paraît idoine. En effet, il possède l'écosystème de drivers et services disponibles pour l'accès aux ressources matérielles, la capacité d'ordonnancement natif ainsi que des bibliothèques pour la sécurité. Toutefois, cette solution engendre des contraintes qui poussent à évaluer d'autres approches. Ce manuscrit évalue la capacité d'un langage de haut niveau tel que Lua à fournir un environnement d'exécution dans le cas d'une implémentation sans système d'exploitation.À travers un écosystème nommé Lynq, cet environnement d'exécution procure les briques nécessaires à la gestion et l'allocation des ressources présentes sur le SoC FPGA, ainsi qu'une méthode proposant une isolation entre applicatifs.La capacité des architectures généralistes que sont les CPUs à devenir spécialisés lorsqu'ils sont implémentés sur un FPGA a été exploré par la suite. Ceci au travers d'une contribution permettant la génération d'un CPU RISC-V ainsi que son microcode associé.Today, embedded systems have taken a leading role in our world. Whether for communication, travel, work or entertainment, their use is preponderant. Together, research and industry efforts are constantly developing various parts that make up these systems: processor, FPGA, memory, operating system.From an architectural point of view, the contribution of a generalist architecture coupled with a reconfigurable architecture positions SoC FPGA as popular targets for use in embedded systems. However, their implementation's complexity makes their adoption difficult. The abstraction of low-level layers seems to be an investigation's axis that would tend to reverse this trend. The use of an operating system seems suitable at first glance because they deliver an ecosystem of drivers and services for access to hardware resources, native scheduling capacities and libraries for security. However, this solution brings constraints and lead to evaluate other approaches.This manuscript evaluates the ability of a high-level language, Lua, to provide an execution environment in such a case that the implementation does not provide operating system. It gives, through an ecosystem named Lynq, the necessary building blocks for the management and allocation of resources present on the SoC FPGA as well as a method for isolation between applications. Besides the adoption of this execution environment, our work explores the capacity of generalist architectures such as CPUs to become specialized when implemented on a FPGA. This is done through a contribution allowing the generation of a RISC-V CPU and its associated microcode