ROLE OF JALAKUMBHI IN UTERINE FIBROID - A CLINICAL STUDY

Uterine fibroid, a noncancerous growth of the uterus that often appear during childbearing age of female and it is one such gynecological disorder which is posing a major health problem. Regardless of benign neoplastic character, uterine fibroids are responsible for significant morbidity in a large segment of the female population. Ayurvedic texts have described Mamsaja granthi which perfectly correlates with benign neoplasm on modern lines. The present study was carried out to evaluate the role of Jalakumbhi Churna in the treatment of uterine fibroid. 30 female patients in reproductive age group who were suffering from uterine fibroid were registered for the present research work. 30 patients were divided equally into 2 groups, 15 patients were treated with Trail group drug i.e. by Jalakumbhi churna 6gm BD for 2 months and 15 patients were treated with Control group drug i.e. Nagakesar churna 6gm BD for 2 months. The diagnoses of uterine fibroids of patients were confirmed by clinical as well as investigation findings. After conducting clinical trial on 30 patients, observation and results were obtained. Statistical analysis shows that both trail and control drug were significantly effective to reduce the cardinal symptoms. As compared to Control drug the effect of Trail drug is better to reduce subjective and objective parameters. Results shows 20% patients were cured and 80% patients were improved after second follow up in trial group, while 26.66% patients were improved and 73.33% patients were not cured after second follow up in control group. Present study concludes that trail drug can definitely be used as adjuvant drug in the management of uterine fibroids.

A CLINICAL STUDY ON AMLAPITTA AND ITS MANAGEMENT WITH CHHINNODBHAVADI GHANAVATI

Amlapitta is a disease prevalent all over the world. The increasing prevalence rate is a constant challenge to the research workers. The disease Amlapitta is a common functional disease of Annavaha srotas. Materialistic life style provokes people to run behind a busy, stressful life with least concern towards proper food habit. The aim of the present study was to find out efficacy of Chhinnodbhavadi Ghanavati in comparison to modern PPI. In present study total 40 patients were taken, divided into 2 equal groups. In group-I: 20 patients were treated with oral administration of trial drug that is Chhinnodbhavadi ghanavati 500mg 2 tab twice a day for 45 days and in group-II: 20 patients were treated with control drug that is Pantaprazole 40mg 1 tab once a day orally for 45 days. After conducting clinical trial on 40 patients, observation and results were obtained. Statistical analysis shows that both trail and control drug were significantly effective to reduce the cardinal symptoms. As compared to trail drug the effect of control drug is better to reduce symptoms. However as compared to side effects and contra-indications of the control drug, it is advisable to use Chhinnodbhavadi Ghanavati for the treatment of Amlapitta for a long period