Progressive = Permissive? Not According to John Dewey…Subjects Matter!

The progressive education movement, which promoted the philosophy of school reform that prevailed among waves of educational innovators throughout the 20th century, has been associated historically with John Dewey and has prided itself on implementing his ‘childcentered’ principles. However, there were major differences between many of the progressives’ attitudes and Dewey’s ideas about learning. To better understand why issues that originally separated Dewey from other progressives continue to be a source of conflict and confusion even today, as exemplified by an article that appeared in an edition of Education Week (Spencer, 2001; Weiner, 2001), this paper examines the philosophy and practices of some significant early progressive thinkers in light of Dewey’s theory of experience

What is affective technotouch (and why does it matter)?

This is the final version. Available on open access from Routledge via the DOI in this recordThis Editors’ Introduction defines the theme of ’affective technotouch’ as referring to multidimensional embodied encounters with technologies which can trigger emotional and affective responses, while also being concerned with social, political, cultural and ethical dimensions of technological touch. With reference to neuroscience and developmental studies, we outline how touch is foundational in human experience. We then discuss contemporary technologies, such as haptic gadgets and care/companion robots, which illustrate the complexities of affective technotouch. Finally, we offer critical outlines of the six contributing articles to this Special Issue on Affective Technotouch.Wellcome Trus

Status and conservation of lion-tailed macaque and other arboreal mammals in tropical rainforests of Sringeri forest range, Western ghats, Karnataka, India

The lion-tailed macaque (Macaca silenus), an endangered primate species, was surveyed in the tropical rainforests of Sringeri in the state of Karnataka, south India. A total of 10 groups and a solitary adult male were found in approximately 90 square kilometers of rainforest. The other sympatric arboreal mammals found included common langurs, bonnet macaques and Malabar giant squirrels. The liontailed macaques are sympatric with other primates and giant squirrels in the undisturbed core areas. More towards the human habitations and disturbed areas, the lion-tailed macaques are absent and the forest is occupied by commensal species. The habitat features and the population structure indicate that this region is a potential area for maintaining a biologically viable population of lion-tailed macaques. However, a number of factors such as extraction of fuel wood, collection of minor forest produce, grazing by domestic livestock and plantation of commercial tree species are causing a serious threat to the habitat. The effect of habitat degradation on arboreal wildlife is discussed and the steps are suggested to minimize the effect of human disturbance on habitat

A phosphoinositide hub connects CLE peptide signaling and polar auxin efflux regulation

Auxin efflux through plasma-membrane-integral PIN-FORMED (PIN) carriers is essential for plant tissue organization and tightly regulated. For instance, a molecular rheostat critically controls PIN-mediated auxin transport in developing protophloem sieve elements of Arabidopsis roots. Plasma-membrane-association of the rheostat proteins, BREVIS RADIX (BRX) and PROTEIN KINASE ASSOCIATED WITH BRX (PAX), is reinforced by interaction with PHOSPHATIDYLINOSITOL-4-PHOSPHATE-5-KINASE (PIP5K). Genetic evidence suggests that BRX dampens autocrine signaling of CLAVATA3/EMBRYO SURROUNDING REGION-RELATED 45 (CLE45) peptide via its receptor BARELY ANY MERISTEM 3 (BAM3). How excess CLE45-BAM3 signaling interferes with protophloem development and whether it does so directly or indirectly remains unclear. Here we show that rheostat polarity is independent of PIN polarity, but interdependent with PIP5K. Catalytically inactive PIP5K confers rheostat polarity without reinforcing its localization, revealing a possible PIP5K scaffolding function. Moreover, PIP5K and PAX cooperatively control local PIN abundance. We further find that CLE45-BAM3 signaling branches via RLCK-VII/PBS1-LIKE (PBL) cytoplasmic kinases to destabilize rheostat localization. Our data thus reveal antagonism between CLE45-BAM3-PBL signaling and PIP5K that converges on auxin efflux regulation through dynamic control of PAX polarity. Because second-site bam3 mutation suppresses root as well as shoot phenotypes of pip5k mutants, CLE peptide signaling likely modulates phosphoinositide-dependent processes in various developmental contexts

Ca2+ signals in plant immunity

Calcium ions function as a key second messenger ion in eukaryotes. Spatially and temporally defined cytoplasmic Ca2+ signals are shaped through the concerted activity of ion channels, exchangers, and pumps in response to diverse stimuli; these signals are then decoded through the activity of Ca2+-binding sensor proteins. In plants, Ca2+ signaling is central to both pattern- and effector-triggered immunity, with the generation of characteristic cytoplasmic Ca2+ elevations in response to potential pathogens being common to both. However, despite their importance, and a long history of scientific interest, the transport proteins that shape Ca2+ signals and their integration remain poorly characterized. Here, we discuss recent work that has both shed light on and deepened the mysteries of Ca2+ signaling in plant immunity

Using the data quality dashboard to improve the ehden network

Federated networks of observational health databases have the potential to be a rich resource to inform clinical practice and regulatory decision making. However, the lack of standard data quality processes makes it difficult to know if these data are research ready. The EHDEN COVID-19 Rapid Collaboration Call presented the opportunity to assess how the newly developed open-source tool Data Quality Dashboard (DQD) informs the quality of data in a federated network. Fifteen Data Partners (DPs) from 10 different countries worked with the EHDEN taskforce to map their data to the OMOP CDM. Throughout the process at least two DQD results were collected and compared for each DP. All DPs showed an improvement in their data quality between the first and last run of the DQD. The DQD excelled at helping DPs identify and fix conformance issues but showed less of an impact on completeness and plausibility checks. This is the first study to apply the DQD on multiple, disparate databases across a network. While study-specific checks should still be run, we recommend that all data holders converting their data to the OMOP CDM use the DQD as it ensures conformance to the model specifications and that a database meets a baseline level of completeness and plausibility for use in research.</p