LOCO-ANS: An Optimization of JPEG-LS Using an Efficient and Low-Complexity Coder Based on ANS

Near-lossless compression is a generalization of lossless compression, where the codec user is able to set the maximum absolute difference (the error tolerance) between the values of an original pixel and the decoded one. This enables higher compression ratios, while still allowing the control of the bounds of the quantization errors in the space domain. This feature makes them attractive for applications where a high degree of certainty is required. The JPEG-LS lossless and near-lossless image compression standard combines a good compression ratio with a low computational complexity, which makes it very suitable for scenarios with strong restrictions, common in embedded systems. However, our analysis shows great coding efficiency improvement potential, especially for lower entropy distributions, more common in near-lossless. In this work, we propose enhancements to the JPEG-LS standard, aimed at improving its coding efficiency at a low computational overhead, particularly for hardware implementations. The main contribution is a low complexity and efficient coder, based on Tabled Asymmetric Numeral Systems (tANS), well suited for a wide range of entropy sources and with simple hardware implementation. This coder enables further optimizations, resulting in great compression ratio improvements. When targeting photographic images, the proposed system is capable of achieving, in mean, 1.6%, 6%, and 37.6% better compression for error tolerances of 0, 1, and 10, respectively. Additional improvements are achieved increasing the context size and image tiling, obtaining 2.3% lower bpp for lossless compression. Our results also show that our proposal compares favorably against state-of-the-art codecs like JPEG-XL and WebP, particularly in near-lossless, where it achieves higher compression ratios with a faster coding speedThis work was supported in part by the Spanish Research Agency through the Project AgileMon under Grant AEI PID2019-104451RB-C2

Screening families of patients with premature coronary heart disease to identify avoidable cardiovascular risk: a cross-sectional study of family members and a general population comparison group

<b>Background:</b> Primary prevention should be targeted at individuals with high global cardiovascular risk, but research is lacking on how best to identify such individuals in the general population. Family history is a good proxy measure of global risk and may provide an efficient mechanism for identifying high risk individuals. The aim was to test the feasibility of using patients with premature cardiovascular disease to recruit family members as a means of identifying and screening high-risk individuals. <b>Findings:</b> We recruited family members of 50 patients attending a cardiology clinic for premature coronary heart disease (CHD). We compared their cardiovascular risk with a general population control group, and determined their perception of their risk and current level of screening. 103 (36%) family members attended screening (27 siblings, 48 adult offspring and 28 partners). Five (5%) had prevalent CHD. A significantly higher percentage had an ASSIGN risk score >20% compared with the general population (13% versus 2%, p < 0.001). Only 37% of family members were aware they were at increased risk and only 50% had had their blood pressure and serum cholesterol level checked in the previous three years. <b>Conclusions:</b> Patients attending hospital for premature CHD provide a mechanism to contact family members and this can identify individuals with a high global risk who are not currently screened

Physical Activity Status in Patients With Coronary Heart Disease: Results From the Cross-Sectional EUROASPIRE Surveys.

BACKGROUND: The study aim was to assess the physical activity levels as well as the intention to become physically active in patients with stable coronary heart disease (CHD) with a special focus on the association with their risk profile. METHODS: Analyses are based on the cross-sectional EUROASPIRE IV surveys. Information was available on 8966 patients in EUROASPIRE III and on 7998 patients in EUROASPIRE IV. Physical activity level according to patients risk profile and their medical management was assessed, the intention to become physically active was investigated and a time trend analysis was performed. RESULTS: A better cardiovascular risk profile as well as receiving physical activity advice or weight loss advice was associated with better physical activity levels. The physical activity status improved significantly over time, the proportion of patients reporting vigorous physical activity for at least 20 minutes ≥ 3 times/week increased from 14.1% to 20.2% (P < .001). Similarly, a significantly greater proportion of patients are in the maintenance stage (36.6% vs. 27.4%) and a smaller proportion in the precontemplation stage (43.2% vs. 52.3%). CONCLUSION: Although an increase was seen in the proportion of patients being adequately physical active, physical activity levels remain suboptimal in many CHD patients

Code renewability for native software protection

Software protection aims at safeguarding assets embedded in software by preventing and delaying reverse engineering and tampering attacks. This article presents an architecture and supporting tool flow to renew parts of native applications dynamically. Renewed and diversified code and data belonging to either the original application or to linked-in protections are delivered from a secure server to a client on demand. This results in frequent changes to the software components when they are under attack, thus making attacks harder. By supporting various forms of diversification and renewability, novel protection combinations become available and existing combinations become stronger. The prototype implementation is evaluated on several industrial use cases

Comparison of pap smear, visual inspection with acetic acid, human papillomavirus DNA-PCR testing and cervicography

Objective: To assess the test qualities of four screening methods to detect cervical intra-epithelial neoplasia in an urban African setting. Method: Six hundred fiftythree women, attending a family planning clinic in Nairobi (Kenya), underwent four concurrent screening methods: pap smear, visual inspection with acetic acid (VIA), PCR for high risk human papillomavirus (HR HPV) and cervicography. The presence of cervical intra-epithelial neoplasia (CIN) was verified by colposcopy or biopsy. Result: Sensitivity (for CIN2 or higher) and specificity (to exclude any CIN or cancer) were 83.3% (95% CI [73.6, 93.0]) and 94.6% (95% CI [92.6, 96.5]), respectively, for pap smear; 73.3% (95% CI [61.8, 84.9]) and 80.0% (95% CI [76.6, 83.4]) for VIA; 94.4% (95% CI [84.6, 98.8]) and 73.9% (95% CI [69.7, 78.2]) for HR HPV; and 72.3% (95% CI [59.1, 85.6]) and 93.2% (95% CI [90.8, 95.7]) for cervicography. Conclusion: The pap smear had the highest specificity (94.6%) and HPV testing the highest sensitivity (94.4%). The visual methods, VIA and cervicography, were similar and showed an accuracy in between the former two tests