3,002 research outputs found
Coastal wetland area change for two freshwater diversions in the Mississippi River Delta
Coastal systems around the globe are being re-integrated with adjacent river systems to restore the natural hydrologic connection to riparian wetlands. The Mississippi River sediment diversions or river reconnections are one such tool to combat high rates of wetland loss in coastal Louisiana, USA by providing freshwater, sediment, and nutrients. There has been some disagreement in the published literature whether re-establishing river reconnection is slowing or contributing to coastal wetland loss. This issue is due to the difficulties in the application of remote sensing in low-relief environments where water level changes could indicate either land loss or simply temporary submergence. We analyzed land change at the receiving areas of two existing freshwater river diversions, Davis Pond and Caernarvon, which have been intermittently receiving river water for up to 2+ decades. This study provides a robust analysis of wetland land change rates in proximity these river diversions including years before river reconnection. Our analyses indicate a net land gain since river reconnection operations began at Davis Pond Diversion (+3.42 km2; range: +2.02–4.81 km2) and no statistically significant change at the Caernarvon Diversion. The Davis Pond wetland results are corroborated with data from a decadal field study documenting increased inorganic sedimentation in the soil. It is clear from this study and others, that river reconnection can increase or, in the case of Caernarvon, have no statistical effect on the land change in these systems due to differences in vegetation, hydroperiod, sediment delivery and external factors including hurricane impacts. Our remote sensing analysis was compared with a global water area change analysis mapping tool which also supported our findings
Experimental Evaluation of Several Key Factors Affecting Root Biomass Estimation by 1500 MHz Ground-Penetrating Radar
Accurate quantification of coarse roots without disturbance represents a gap in our understanding of belowground ecology. Ground penetrating radar (GPR) has shown significant promise for coarse root detection and measurement, however root orientation relative to scanning transect direction, the difficulty identifying dead root mass, and the effects of root shadowing are all key factors affecting biomass estimation that require additional research. Specifically, many aspects of GPR applicability for coarse root measurement have not been tested with a full range of antenna frequencies. We tested the effects of multiple scanning directions, root crossover, and root versus soil moisture content in a sand-hill mixed oak community using a 1500 MHz antenna, which provides higher resolution than the oft used 900 MHz antenna. Combining four scanning directions produced a significant relationship between GPR signal reflectance and coarse root biomass (R2 = 0.75) (p \u3c 0.01) and reduced variability encountered when fewer scanning directions were used. Additionally, significantly fewer roots were correctly identified when their moisture content was allowed to equalize with the surrounding soil (p \u3c 0.01), providing evidence to support assertions that GPR cannot reliably identify dead root mass. The 1500 MHz antenna was able to identify roots in close proximity of each other as well as roots shadowed beneath shallower roots, providing higher precision than a 900 MHz antenna. As expected, using a 1500 MHz antenna eliminates some of the deficiency in precision observed in studies that utilized lower frequency antennas
Genome-wide association study identifies common and low-frequency variants at the AMHgene locus that strongly predict serum AMH levels in males
Anti-Müllerian hormone (AMH) is an essential messenger of sexual differentiation in the foetus and is an emerging biomarker of postnatal reproductive function in females. Due to a paucity of adequately sized studies, the genetic determinants of circulating AMH levels are poorly characterized. In samples from 2815 adolescents aged 15 from the ALSPAC study, we performed the first genome-wide association study of serum AMH levels across a set of ∼9 M ‘1000 Genomes Reference Panel’ imputed genetic variants. Genetic variants at the AMH protein-coding gene showed considerable allelic heterogeneity, with both common variants [rs4807216 (PMale = 2 × 10−49, Beta: ∼0.9 SDs per allele), rs8112524 (PMale = 3 × 10−8, Beta: ∼0.25)] and low-frequency variants [rs2385821 (PMale = 6 × 10−31, Beta: ∼1.2, frequency 3.6%)] independently associated with apparently large effect sizes in males, but not females. For all three SNPs, we highlight mechanistic links to AMH gene function and demonstrate highly significant sex interactions (PHet 0.0003–6.3 × 10−12), culminating in contrasting estimates of trait variance explained (24.5% in males versus 0.8% in females). Using these SNPs as a genetic proxy for AMH levels, we found no evidence in additional datasets to support a biological role for AMH in complex traits and diseases in men
Foot pressure distributions during walking in African elephants (Loxodonta africana)
Elephants, the largest living land mammals, have evolved a specialized foot morphology to help reduce locomotor pressures while supporting their large body mass. Peak pressures that could cause tissue damage are mitigated passively by the anatomy of elephants' feet, yet this mechanism does not seem to work well for some captive animals. This study tests how foot pressures vary among African and Asian elephants from habitats where natural substrates predominate but where foot care protocols differ. Variations in pressure patterns might be related to differences in husbandry, including but not limited to trimming and the substrates that elephants typically stand and move on. Both species' samples exhibited the highest concentration of peak pressures on the lateral digits of their feet (which tend to develop more disease in elephants) and lower pressures around the heel. The trajectories of the foot's centre of pressure were also similar, confirming that when walking at similar speeds, both species load their feet laterally at impact and then shift their weight medially throughout the step until toe-off. Overall, we found evidence of variations in foot pressure patterns that might be attributable to husbandry and other causes, deserving further examination using broader, more comparable samples
Genetic Regulation of Puberty Timing in Humans.
Understanding the regulation of puberty timing has relevance to developmental and human biology and to the pathogenesis of various diseases. Recent large-scale genome-wide association studies on puberty timing and adult height, body mass index (BMI) and central body shape provide evidence for shared biological mechanisms that regulate these traits. There is a substantial genetic overlap between age at menarche in women and BMI, with almost invariable directional consistency with the epidemiological associations between earlier menarche and higher BMI. By contrast, the genetic loci identified for age at menarche are largely distinct from those identified for central body shape, while alleles that confer earlier menarche can be associated with taller or shorter adult height. The findings of population-based studies on age at menarche show increasing relevance for other studies of rare monogenic disorders and enrich our understanding of the mechanisms that regulate the timing of puberty and reproductive function.This work was supported by the MRC.This is the author accepted manuscript. The final version is available from Karger at http://www.karger.com/Article/Abstract/43102
Deformation of Silica Aerogel During Fluid Adsorption
Aerogels are very compliant materials - even small stresses can lead to large
deformations. In this paper we present measurements of the linear deformation
of high porosity aerogels during adsorption of low surface tension fluids,
performed using a Linear Variable Differential Transformer (LVDT). We show that
the degree of deformation of the aerogel during capillary condensation scales
with the surface tension, and extract the bulk modulus of the gel from the
data. Furthermore we suggest limits on safe temperatures for filling and
emptying low density aerogels with helium.Comment: 8 pages, 5 figures, submitted to PR
Nonenzymatically Glucosylated Albumin: In Vitro Preparation and Isolation from Normal Human Serum
Incubation of human serum with D-[6-3H]glucose resulted in the gradual accumulation of radioactivity in acid-precipitable material. Upon chromatography on Sephadex G-200, radioactivity was found associated with each of the major molecular weight classes of serum protein. Purified human serum albumin was also glucosylated in vitro upon exposure to D-[6-3H]glucose in phosphate-buffered saline. The glucosylated and unmodified albumins were separated by ion exchange chromatography. The physiological significance of these observations in vitro was confirmed by the isolation and quantitation of glucosylated albumin from normal human serum. Glucosylated albumin represents approximately 6 to 15% of total serum albumin in normal adults. The post-translational modification appears to occur by a nonenzymatic process analogous to that responsible for glucosylation of hemoglobin A to hemoglobin AIc, i.e. through Schiff base formation and Amadori rearrangement to a ketoamine derivative
Elucidating the genetic basis of social interaction and isolation.
The negative impacts of social isolation and loneliness on health are well documented. However, little is known about their possible biological determinants. In up to 452,302 UK Biobank study participants, we perform genome-wide association study analyses for loneliness and regular participation in social activities. We identify 15 genomic loci (P < 5 × 10-8) for loneliness, and demonstrate a likely causal association between adiposity and increased susceptibility to loneliness and depressive symptoms. Further loci were identified for regular attendance at a sports club or gym (N = 6 loci), pub or social club (N = 13) or religious group (N = 18). Across these traits there was strong enrichment for genes expressed in brain regions that control emotional expression and behaviour. We demonstrate aetiological mechanisms specific to each trait, in addition to identifying loci that are pleiotropic across multiple complex traits. Further study of these traits may identify novel modifiable risk factors associated with social withdrawal and isolation
Robotic Lepidoptery: Structural Characterization of (mostly) Unexpected Palladium Complexes Obtained from High-Throughput Catalyst Screening
In the course of a high-throughput search for optimal combinations of bidentate ligands with Pd(II) carboxylates to generate oxidation catalysts, we obtained and crystallographically characterized a number of crystalline products. While some combinations afforded the anticipated (L-L)Pd(OC(O)R)_2 structures (L-L = bipyridine, tmeda; R = CH_3, CF_3), many gave unusual oligometallic complexes resulting from reactions such as C−H activation (L-L = sparteine), P−C bond cleavage (L-L = 1,2-bis(diphenylphosphino)ethane, and C−C bond formation between solvent (acetone) and ligand (L-L = 1,4-bis(2,6-diisopropylphenyl)-1,4-diaza-1,3-butadiene). These findings illustrate potential pitfalls of screening procedures based on assuming uniform, in situ catalyst self-assembly
Effects of Gas Flaring on the Behavior of Night-migrating Birds at an Artificial Oil-production Island, Arctic Alaska
We studied movement rates and the general flight behavior of bird flocks seen on radar and recorded visually at Northstar Island, Arctic Alaska, from 13 to 27 September 2002. Most of this period (13 – 19 and 21 – 27 September) had no gas-flaring events, but a major gas-flaring event occurred on the night of 20 September. Movement rates of targets on radar and of bird flocks recorded visually in the first ~50% – 60% of the night were much lower during the non-flaring period than during the night of flaring, whereas rates in the last ~40% – 50% of the night were similar in all periods. The general flight behavior of birds also differed significantly, with higher percentages of both radar targets and bird flocks exhibiting straight-line (directional) flight behaviors during the non-flaring periods and higher percentages of radar targets and bird flocks exhibiting non-straight-line (erratic and circling) flight behaviors during the gas-flaring period. During the night of gas flaring, the bright illumination appeared to have an effect only after sunset, when flocks of birds circled the island after being drawn in from what appeared to be a substantial distance from the island. On both radar and visual sampling, the number of bird flocks approaching the island declined over the evening, and the attractiveness of the light from flaring appeared to decline. The visibility of the moon appeared to have little effect on the behavior of birds. Because illumination from extensive gas-flaring is such a strong attractant to migrating birds and because most bird flocks fly at low altitudes over the water, flaring booms on coastal and offshore oil-production platforms in Arctic Alaska should be positioned higher than the mean flight altitudes of migrating birds to reduce the chances of incineration.Nous avons étudié les taux de déplacement et le comportement de vol général des troupeaux d’oiseaux captés par radar ou consignés visuellement à l’île Northstar, dans l’Alaska de l’Arctique, du 13 au 27 septembre 2002. Pendant presque toute cette période (du 13 au 19 et du 21 au 27 septembre), il n’y a pas eu de brûlage de gaz à la torche, mais la nuit du 20 septembre, il y a eu un important brûlage de gaz à la torche. Les taux de déplacement des cibles radar et des troupeaux d’oiseaux consignés visuellement pendant la première tranche d’environ 50 % à 60 % de la nuit étaient beaucoup moins élevés pendant la période où il n’y avait pas de brûlage à la torche que pendant la nuit où il y a eu brûlage à la torche, tandis que pendant la deuxième tranche d’environ 40 % à 50 % de la nuit, les taux de déplacement étaient semblables pendant toutes les périodes. Le comportement de vol général des oiseaux a également affiché une différence considérable. De plus grands pourcentages de cibles radar et de troupeaux d’oiseaux adoptaient un comportement de vol rectiligne (direct) pendant les périodes où il n’y avait pas de brûlage à la torche, et de plus grands pourcentages de cibles radar et de troupeaux d’oiseaux affichaient un comportement de vol non rectiligne (erratique et indirect) pendant la période où il y a eu brûlage à la torche. La nuit du brûlage à la torche, la vive illumination n’a semblé avoir un effet qu’après le coucher du soleil, quand les troupeaux d’oiseaux encerclaient l’île après avoir été attirés depuis un endroit qui semblait très lointain. Tant pour l’échantillonnage prélevé par radar que par consignation visuelle, le nombre de troupeaux d’oiseaux s’approchant de l’île diminuait dans le courant de la soirée, et l’attrait de la lumière émanant du brûlage à la torche semblait également diminuer. La visibilité de la lune semblait avoir peu d’effet sur le comportement des oiseaux. Puisque l’illumination provenant du brûlage prolongé à la torche exerce une si grande force d’attraction chez les oiseaux migrateurs, et puisque la plupart des troupeaux d’oiseaux volent en basse altitude au-dessus de l’eau, le torchage effectué sur les plateformes pétrolières côtières et extracôtières dans l’Alaska de l’Arctique devrait être positionné plus haut que les altitudes moyennes de vol des oiseaux migrateurs afin de réduire les risques d’incinération
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