Recent work at the World Data Centre for Geomagnetism (Edinburgh)

Observatory data holdings at the World Data Centre for Geomagnetism (Edinburgh) www.wdc.bgs.ac.uk include minute, hourly and annual mean values of the geomagnetic field from over 500 observatories since the early 19th century. We describe ongoing maintenance of this important data resource, data-checking procedures developed with global modelling in mind, and some recent additions and corrections

Estimating the extremes in European geomagnetic activity

Rapidly changing geomagnetic field variations constitute a natural hazard, for example in navigation and, through geomagnetically induced currents, to power grids and pipeline networks. To understand this hazard we have continuous magnetic measurements across the world for typically less than 100 years. Much of the older data is also in analogue form, or is only available digitally as hourly or daily magnetic indices or mean levels. So it may not yet be clear what the true extremes in geomagnetic variations are, particularly on time scales - seconds to minutes - that are relevant for estimating the hazard to technological systems. We therefore use a number of decades of one minute samples of magnetic data from observatories across Europe, together with the technique of 'extreme value statistics’ to explore estimated maxima in field variations in the horizontal strength and in the declination of the field. These maxima are expressed in terms of the variations that might be observed once every 100 and 200 years. We also examine the extremes in one-minute rates of change of these field components over similar time scales. The results should find application in both hazard assessment for technologies and in navigation applications. The results can also be used to more rigorously answer the often-asked question: “just how large can geomagnetic storms and field variations be?

Geomagnetic extreme statistics for Europe

Rapidly changing geomagnetic field variations constitute a natural hazard, for example to grounded power grids and pipeline networks. To understand this hazard we have continuous magnetic measurements across the world for typically less than 100 years. Much of the older data is also in analogue form, or is only available digitally as hourly or daily magnetic indices or mean levels. So it may not yet be clear what the true extremes in geomagnetic variation are, particularly on time scales - seconds to minutes - that are relevant for estimating the hazard to technological systems. We therefore use a number of decades of one minute samples of magnetic data from observatories in Europe, together with the technique of 'extreme value statistics', to explore estimated maxima in field variations in the horizontal strength and in the declination of the field. These maxima are expressed, for example, in terms of the variations that might be observed on time scales of 100 and 200 years. We also examine the extremes in the one-minute rate of change of these field components on similar time scales. The results should find application in hazard assessment and navigation applications

Intimate Uncertainties: A Mother Returns to Poetic Inquiry

Poetic inquiry offers the opportunity to become intimate with those multiple facets of self that shape our understanding. However, as scholars, even when we engage in creative forms of inquiry, we often find ourselves driven to ignore certain aspects of our identities. To acknowledge the personal within our research is uncomfortable and some have even argued, irrelevant. I believe our stories of the personal are extremely relevant, reflecting a landscape of multiple, fluid, intersecting and often contradictory subjectivities. As scholars, each of us has or will struggle at some point along our journey in relationship to our place within our work of doing research. The struggles may be different, but the discomfort is shared. Across the space of this article I use poetic inquiry to enter into discomfort and uncertainly as I try to make sense of what it means to engage in scholarship as a new mother. Through poetic inquiry my story does not exist in isolation, but instead becomes one of many in the larger dialogue of discomfort, uncertainty, self and possibility across the landscape of doing research and being human.Poetic Inquiry erlaubt eine Annäherung an die zahlreichen Facetten des Selbst, aus deren Zusammenspiel Verstehen möglich wird. Dennoch sehen wir uns als Forschende, auch wenn wir kreative Untersuchungsmethoden nutzen, immer wieder veranlasst, spezifische Anteile unserer Identität zu ignorieren. Persönliches in unserer Forschung anzuerkennen ist unbequem, einige würden auch sagen: irrelevant. Ich hingegen erachte es als außerordentlich bedeutsam, da es zugleich das Multiple, Fluide, sich Überschneidende und oft auch Widersprüchliche von Subjektivität fassbar macht. Als Wissenschaftler/innen haben die meisten von uns bereits irgendwann um die je eigene Situierung im Forschungsprozess gerungen, anderen steht es noch bevor. Auch wenn die Kämpfe, die wir dann mit uns führen, unterschiedlich sein mögen, ist ihnen ein gewisses Unbehagen gemeinsam. In diesem Beitrag greife ich auf Poetic Inquiry zurück, um das Unbehagen und die Verunsicherung verstehen zu können, die ich erlebte, als ich mich - gerade Mutter geworden - wieder meiner Forschungsarbeit zuwendete. Auf diese Weise bleibt meine eigene Geschichte nicht isoliert, sondern wird Teil eines breiteren Dialogs über Unbehagen, Unsicherheit und die Möglichkeit, sich sowohl als Forscher/in als auch als Person im Forschungsprozess zu situieren

Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model.

Pancreatic duct glands (PDGs) have been hypothesized to give rise to pancreatic intraepithelial neoplasia (PanIN). Treatment with the glucagon-like peptide (GLP)-1 analog, exendin-4, for 12 weeks induced the expansion of PDGs with mucinous metaplasia and columnar cell atypia resembling low-grade PanIN in rats. In the pancreata of Pdx1-Cre; LSL-Kras(G12D) mice, exendin-4 led to acceleration of the disruption of exocrine architecture and chronic pancreatitis with mucinous metaplasia and increased formation of murine PanIN lesions. PDGs and PanIN lesions in rodent and human pancreata express the GLP-1 receptor. Exendin-4 induced proproliferative signaling pathways in human pancreatic duct cells, cAMP-protein kinase A and mitogen-activated protein kinase phosphorylation of cAMP-responsive element-binding protein, and increased cyclin D1 expression. These GLP-1 effects were more pronounced in the presence of an activating mutation of Kras and were inhibited by metformin. These data reveal that GLP-1 mimetic therapy may induce focal proliferation in the exocrine pancreas and, in the context of exocrine dysplasia, may accelerate formation of neoplastic PanIN lesions and exacerbate chronic pancreatitis

A Baroque Evening

Kemp Recital Hall February 29, 2000 Tuesday Evening 8:00 p.m

Faculty Recital:Sarah Gentry, Violin Julian Dawson, Piano

Kemp Recital Hall Tuesday Evening September 3, 2002 8:00 p.m

Wonder Woman Complex

Writings and artwork deconstructing the institution of marriage, beauty standards, motherhood, and work ( the glorification of busy ).https://digitalcommons.chapman.edu/feminist_zines/1028/thumbnail.jp

Exploring heritage through time and space : Supporting community reflection on the highland clearances

On the two hundredth anniversary of the Kildonan clearances, when people were forcibly removed from their homes, the Timespan Heritage centre has created a program of community centred work aimed at challenging pre conceptions and encouraging reflection on this important historical process. This paper explores the innovative ways in which virtual world technology has facilitated community engagement, enhanced visualisation and encouraged reflection as part of this program. An installation where users navigate through a reconstruction of pre clearance Caen township is controlled through natural gestures and presented on a 300 inch six megapixel screen. This environment allows users to experience the past in new ways. The platform has value as an effective way for an educator, artist or hobbyist to create large scale virtual environments using off the shelf hardware and open source software. The result is an exhibit that also serves as a platform for experimentation into innovative ways of community co-creation and co-curation.Postprin