Seismic analysis of the acid liquid waste tanks at the Western New York State Nuclear Service Center, West Valley, New York

This report was prepared at the request of the Nuclear Regulatory Commission as part of a review of the nuclear fuel reprocessing plant operated by Nuclear Fuel Services, Inc., at West Valley, NY. The report discusses the seismic integrity evaluation by Lawrence Livermore Laboratory of two high-level, acid liquid-waste tanks, 8D-3 and 8D-4, adjacent to the plant. It describes the tanks and discusses the techniques used to model and analyze the structures and to combine the loads. Limiting criteria, results, and conclusions are presented

Seismic evaluation of the U1a complex at the Nevada Test Site

As part of an overall safety evaluation of the Ula Complex, a seismic evaluation of structures, systems, and components (SSC) was conducted. A team of seismic, safety, and operation engineers from Los Alamos National Laboratory (LANL), Bechtel Nevada (BN) and Lawrence Livermore National Laboratory (LLNL) was chartered to perform the seismic evaluation. The UlA Complex is located in Area 1 of the Nevada Test Site (NTS) in Nevada. The complex is a test facility for physics experiments in support of the Science Based Stockpile Stewardship Program. The Ula Complex consists of surface and subsurface facilities. The subsurface facility is a tunnel complex located 963 feet below the surface. The seismic evaluation of U 1 a Complex is required to comply with the DOE Natural Phenomena Policy. This policy consists of an order, an implementing guide, and standards which provide guidance for design and evaluation of SSCs, categorization of SSCs, characterization of site, and hazard level definition

A physical map of the chicken genome

Strategies for assembling large, complex genomes have evolved to include a combination of whole-genome shotgun sequencing and hierarchal map-assisted sequencing. Whole-genome maps of all types can aid genome assemblies, generally starting with low-resolution cytogenetic maps and ending with the highest resolution of sequence. Fingerprint clone maps are based upon complete restriction enzyme digests of clones representative of the target genome, and ultimately comprise a near-contiguous path of clones across the genome. Such clone-based maps are used to validate sequence assembly order, supply long-range linking information for assembled sequences, anchor sequences to the genetic map and provide templates for closing gaps. Fingerprint maps are also a critical resource for subsequent functional genomic studies, because they provide a redundant and ordered sampling of the genome with clones. In an accompanying paper we describe the draft genome sequence of the chicken, Gallus gallus, the first species sequenced that is both a model organism and a global food source. Here we present a clone-based physical map of the chicken genome at 20-fold coverage, containing 260 contigs of overlapping clones. This map represents approximately 91% of the chicken genome and enables identification of chicken clones aligned to positions in other sequenced genomes

Genome Res.

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC library. These BAC clones provide 13-fold redundant coverage of the genome and have been assembled into 376 fingerprint contigs. A yeast artificial chromosome (YAC) map was also constructed and aligned with the BAC map via fingerprinted BAC and P1 artificial chromosome clones (PACs) sharing interspersed repetitive sequence markers with the YAC-based physical map. We have annotated 95% of the fingerprint map clones in contigs with coordinates on the version 3.1 rat genome sequence assembly, using BAC-end sequences and in silico mapping methods. These coordinates have allowed anchoring 358 of the 376 fingerprint map contigs onto the sequence assembly. Of these, 324 contigs are anchored to rat genome sequences localized to chromosomes, and 34 contigs are anchored to unlocalized portions of the rat sequence assembly. The remaining 18 contigs, containing 54 clones, still require placement. The fingerprint map is a high-resolution integrative data resource that provides genome-ordered associations among BAC, YAC, and PAC clones and the assembled sequence of the rat genome. [Supplemental material is available online at www.genome.org.

Genome Res

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC library. These BAC clones provide ~13-fold redundant coverage of the genome and have been assembled into 376 fingerprint contigs. A yeast artificial chromosome (YAC) map was also constructed and aligned with the BAC map via fingerprinted BAC and P1 artificial chromosome clones (PACs) sharing interspersed repetitive sequence markers with the YAC-based physical map. We have annotated 95% of the fingerprint map clones in contigs with coordinates on the version 3.1 rat genome sequence assembly, using BAC-end sequences and in silico mapping methods. These coordinates have allowed anchoring 358 of the 376 fingerprint map contigs onto the sequence assembly. Of these, 324 contigs are anchored to rat genome sequences localized to chromosomes, and 34 contigs are anchored to unlocalized portions of the rat sequence assembly. The remaining 18 contigs, containing 54 clones, still require placement. The fingerprint map is a high-resolution integrative data resource that provides genome-ordered associations among BAC, YAC, and PAC clones and the assembled sequence of the rat genome

Investigating the effects of personality traits on pair programming in a higher education setting through a family of experiments

Evidence from our systematic literature review revealed numerous inconsistencies in findings from the Pair Programming (PP) literature regarding the effects of personality on PP’s effectiveness as a pedagogical tool. In particular: i) the effect of differing personality traits of pairs on the successful implementation of pair-programming (PP) within a higher education setting is still unclear, and ii) the personality instrument most often used had been Myers-Briggs Type Indicator (MBTI), despite being an indicator criticized by personality psychologists as unreliable in measuring an individual’s personality traits. These issues motivated the research described in this paper. We conducted a series of five formal experiments (one of which was a replicated experiment), between 2009 and 2010, at the University of Auckland, to investigate the effects of personality composition on PP’s effectiveness. Each experiment looked at a particular personality trait of the Five-Factor personality framework. This framework comprises five broad traits (Openness to experience, Conscientiousness, Extraversion, Agreeableness, and Neuroticism), and our experiments focused on three of these - Conscientiousness, Neuroticism, and Openness. A total of 594 undergraduate students participated as subjects. Overall, our findings for all five experiments, including the replication, showed that Conscientiousness and Neuroticism did not present a statistically significant effect upon paired students’ academic performance. However, Openness played a significant role in differentiating paired students’ academic performance. Participants’ survey results also indicated that PP not only caused an increase in satisfaction and confidence levels but also brought enjoyment to the tutorial classes and enhanced students’ motivation