3,117 research outputs found
Magnetic Monopole Noise
Magnetic monopoles are hypothetical elementary particles exhibiting quantized
magnetic charge and quantized magnetic flux . A classic proposal for detecting such magnetic charges is to measure the
quantized jump in magnetic flux threading the loop of a superconducting
quantum interference device (SQUID) when a monopole passes through it.
Naturally, with the theoretical discovery that a plasma of emergent magnetic
charges should exist in several lanthanide-pyrochlore magnetic insulators,
including DyTiO, this SQUID technique was proposed for their direct
detection. Experimentally, this has proven extremely challenging because of the
high number density, and the generation-recombination (GR) fluctuations, of the
monopole plasma. Recently, however, theoretical advances have allowed the
spectral density of magnetic-flux noise due to GR
fluctuations of magnetic charge pairs to be determined. These
theories present a sequence of strikingly clear predictions for the
magnetic-flux noise signature of emergent magnetic monopoles. Here we report
development of a high-sensitivity, SQUID based flux-noise spectrometer, and
consequent measurements of the frequency and temperature dependence of
for DyTiO samples. Virtually all the elements
of predicted for a magnetic monopole plasma, including the
existence of intense magnetization noise and its characteristic frequency and
temperature dependence, are detected directly. Moreover, comparisons of
simulated and measured correlation functions of the magnetic-flux
noise imply that the motion of magnetic charges is strongly
correlated because traversal of the same trajectory by two magnetic charges of
same sign is forbidden
Visits to rheumatologists for arthritis: The role of access to primary care physicians, geographic availability of rheumatologists, and socioeconomic status
Objective. This multilevel study examines access to rheumatologists for all arthritis and inflammatory arthritis, taking into account geographic availability of rheumatologists, access to primary care physicians (PCPs), and population characteristics (e.g., socioeconomic status [SES]). Methods. We analyzed data from the population (age ≤18 years) living in the 105 health planning areas in Ontario, Canada on visits to physicians for arthritis and musculoskeletal disorders. Using data from a survey of rheumatologists and Geographic Information System analysis, an index of geographic availability for rheumatologists was calculated, incorporating distance between the population and rheumatologist locations and the number of hours per week of rheumatologist care. Multilevel Poisson regression was used to examine factors associated with the rates of rheumatology visits for inflammatory arthritis and all arthritis. Results. Controlling for age and sex, the rheumatologist availability index was associated with visit rates for all arthritis, but not inflammatory arthritis. Patients living in areas with low access to PCPs or low SES were less likely to have office visits to rheumatologists for all arthritis and inflammatory arthritis. Conclusion. Besides potential deficiencies in rheumatology provision, there may be access barriers to rheumatology services, particularly for populations with low access to PCPs or low SES. This is of special concern for patients with inflammatory arthritis for whom rheumatologist care is necessary. In developing models of care for arthritis, this study points to the need to pay attention to areas with low PCP resources and areas of low SES, as well as the location and amount of rheumatology services available
Nurses\u27 Alumnae Association Bulletin, April 1962
Staff Nurses Association
Alumnae Meetings 1961
Social Committee
Clara Melville Scholarship Fund
Ways and Means Report
Cook Book Report
Bulletin Committee
Private Duty Nurse\u27s Section
Hospital Report and Nursing Service
Federal Nursing Service
Practice of Nursing
Report of Student Council Activities
Medical Work in Ghan
Power of grammatical evolution neural networks to detect gene-gene interactions in the presence of error
<p>Abstract</p> <p>Background</p> <p>With the advent of increasingly efficient means to obtain genetic information, a great insurgence of data has resulted, leading to the need for methods for analyzing this data beyond that of traditional parametric statistical approaches. Recently we introduced Grammatical Evolution Neural Network (GENN), a machine-learning approach to detect gene-gene or gene-environment interactions, also known as epistasis, in high dimensional genetic epidemiological data. GENN has been shown to be highly successful in a range of simulated data, but the impact of error common to real data is unknown. In the current study, we examine the power of GENN to detect interesting interactions in the presence of noise due to genotyping error, missing data, phenocopy, and genetic heterogeneity. Additionally, we compare the performance of GENN to that of another computational method – Multifactor Dimensionality Reduction (MDR).</p> <p>Findings</p> <p>GENN is extremely robust to missing data and genotyping error. Phenocopy in a dataset reduces the power of both GENN and MDR. GENN is reasonably robust to genetic heterogeneity and find that in some cases GENN has substantially higher power than MDR to detect functional loci in the presence of genetic heterogeneity.</p> <p>Conclusion</p> <p>GENN is a promising method to detect gene-gene interaction, even in the presence of common types of error found in real data.</p
Multi-Atom Quasiparticle Scattering Interference for Superconductor Energy-Gap Symmetry Determination
Complete theoretical understanding of the most complex superconductors
requires a detailed knowledge of the symmetry of the superconducting energy-gap
, for all momenta on the Fermi surface
of every band . While there are a variety of techniques for determining
, no general method existed to measure the signed
values of . Recently, however, a new technique based
on phase-resolved visualization of superconducting quasiparticle interference
(QPI) patterns centered on a single non-magnetic impurity atom, was introduced.
In principle, energy-resolved and phase-resolved Fourier analysis of these
images identifies wavevectors connecting all k-space regions where
has the same or opposite sign. But use of a single
isolated impurity atom, from whose precise location the spatial phase of the
scattering interference pattern must be measured is technically difficult. Here
we introduce a generalization of this approach for use with multiple impurity
atoms, and demonstrate its validity by comparing the
it generates to the determined from single-atom
scattering in FeSe where energy-gap symmetry is established. Finally,
to exemplify utility, we use the multi-atom technique on LiFeAs and find
scattering interference between the hole-like and electron-like pockets as
predicted for of opposite sign
emb-1 Encodes the APC16 Subunit of the Caenorhabditis elegans Anaphase-Promoting Complex
In the nematode Caenorhabditis elegans, temperature-sensitive mutants of emb-1 arrest as one-cell embryos in metaphase of meiosis I in a manner that is indistinguishable from embryos that have been depleted of known subunits of the anaphase-promoting complex or cyclosome (APC/C). Here we show that the emb-1 phenotype is enhanced in double mutant combinations with known APC/C subunits and suppressed in double mutant combinations with known APC/C suppressors. In addition to its meiotic function, emb-1 is required for mitotic proliferation of the germline. These studies reveal that emb-1 encodes K10D2.4, a homolog of the small, recently discovered APC/C subunit, APC16
Two-step synthesis of Fe2O3 and Co3O4 nanoparticles: towards a general method for synthesizing nanocrystalline metal oxides with high surface area and thermal stability
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.A simple, two-step method using activated carbon (AC) as a support/scaffold was developed to synthesize metal oxide nanocrystalline materials (NCMs). In the first step, metal nitrate precursors were deposited by wet impregnation onto the AC, then heated in argon at 350 °C to immobilize the metal oxides. In the second step, the AC was removed by calcination in air at 500 °C, to obtain the unsupported metal oxide NCMs. Characterization by N2-sorption isotherms, TGA, XPS and EXAFS reveals that the metal oxide particles are crystalline and nanometre-sized, with surface areas up to 148 m2 g−1. Moreover, the TEM images show particle sizes in the range 5–10 nm, even after calcination at 500 °C for 2 h. Their thermal stability and high surface areas, together with the nanometre-sized structures, make them promising materials for catalytic applications (e.g., CO oxidation).DFG, EXC 314, Unifying Concepts in Catalysi
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Observed suppression of ozone formation at extremely high temperatures due to chemical and biophysical feedbacks
Ground level ozone concentrations ([O3]) typically show a direct linear relationship with surface air temperature. Three decades of California measurements provide evidence of a statistically significant change in the ozone-temperature slope (ΔmO3-T) under extremely high temperatures (> 312 K). This ΔmO3-T leads to a plateau or decrease in [O3], reflecting the diminished role of nitrogen oxide sequestration by peroxyacetyl nitrates and reduced biogenic isoprene emissions at high temperatures. Despite inclusion of these processes in global and regional chemistry-climate models, a statistically significant change in ΔmO3-T has not been noted in prior studies. Future climate projections suggest a more frequent and spatially widespread occurrence of this ΔmO3-T response, confounding predictions of extreme ozone events based on the historically observed linear relationship
Xtn3 is a developmentally expressed cardiac and skeletal muscle-specific novex-3 titin isoform
Titin proteins play an essential role in maintaining muscle function and structure. Recent work has implicated the involvement of the novex-3 titin isoform in sarcomere restructuring and disease. Unlike avian and mammalian systems, Xenopus laevis myogenesis is characterized by a wave of primary myogenesis followed by apoptosis of the primary muscles and formation of new muscles by secondary myogenesis. We show here that the Xenopus laevis novex-3 titin isoform (Xtn3) is developmentally expressed throughout the somites, heart, and primary muscles of the developing embryo. Downregulation of Xtn3 expression at tadpole stages appears to coincide with the change in myofiber composition from solely embryonic “fast” fiber types to myofibers containing both “fast” and “slow” fiber types. We demonstrate that Xtn3 is expressed early in the presomitic mesoderm and remains expressed in the somites, ventral myoblasts, and developing jaw muscles through late tailbud stage. Furthermore, we show that Xtn3 is expressed in the cardiac primordia prior to linear heart tube formation and remains expressed in the heart until tadpole stage, at which point it is downregulated in the heart except in discrete patches of cardiac cells. Finally, we demonstrate that Xtn3 transcripts are detectable in adult heart and muscle tissues
Health, Nutrition and Healthcare Availability (Survey 2, Report 2)
With support and collaboration from the W.K. Kellogg Foundation through the America Healing initiative, researchers at the University of Michigan are leading the National Voices Project (NVP) from 2011-2015. The central goals of the NVP are to examine the sources of racial/ethnic inequity and other disparities for children in the United States today, identify interventions that address disparities effectively, and inform the public dialogue about racial healing and racial equality. The NVP offers a fresh perspective on community-level opportunities for children throughout the country, in the domains of health and nutrition, education, and economic security -- through the eyes of adults whose work and volunteer efforts affect such opportunities. In other words, the NVP reflects the perceptions of individuals throughout the United States who are in a position to improve children's opportunities in the future. The questionnaire for NVP Survey 2 was developed by the National Voices Project team at the University of Michigan, with input from WKKF collaborators. We examined how individuals who work or volunteer with children view opportunities for education, health and healthcare, and economic well-being related to children and adolescents. Many of the questions were identical to questions fielded for NVP Survey 1 in 2011, to facilitate comparisons of responses across these different samples and over time. New questions in NVP Survey 2 centered on respondents' perceptions of segregation and inequities in the communities they know best, and on respondents' awareness about efforts to bridge racial/ethnic inequities in those communities
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