4,746 research outputs found

    Linear Approximations and Tests of Conditional Pricing Models

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    We construct a simple reduced-form example of a conditional pricing model with modest intrinsic nonlinearity. The theoretical magnitude of the pricing errors (alphas) induced by the application of standard linear conditioning are derived as a direct consequence of an omitted variables bias. When the model is calibrated to either characteristics sorted or industry portfolios, we find that the alphas generated by approximation-induced specification error are economically large. A Monte Carlo analysis shows that finite-sample alphas are even larger. It also shows that the power to detect omitted nonlinear factors through tests based on estimated risk premiums can sometimes be quite low, even when the effect of misspecification on alphas is large.

    Algebraic and combinatorial aspects of sandpile monoids on directed graphs

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    The sandpile group of a graph is a well-studied object that combines ideas from algebraic graph theory, group theory, dynamical systems, and statistical physics. A graph's sandpile group is part of a larger algebraic structure on the graph, known as its sandpile monoid. Most of the work on sandpiles so far has focused on the sandpile group rather than the sandpile monoid of a graph, and has also assumed the underlying graph to be undirected. A notable exception is the recent work of Babai and Toumpakari, which builds up the theory of sandpile monoids on directed graphs from scratch and provides many connections between the combinatorics of a graph and the algebraic aspects of its sandpile monoid. In this paper we primarily consider sandpile monoids on directed graphs, and we extend the existing theory in four main ways. First, we give a combinatorial classification of the maximal subgroups of a sandpile monoid on a directed graph in terms of the sandpile groups of certain easily-identifiable subgraphs. Second, we point out certain sandpile results for undirected graphs that are really results for sandpile monoids on directed graphs that contain exactly two idempotents. Third, we give a new algebraic constraint that sandpile monoids must satisfy and exhibit two infinite families of monoids that cannot be realized as sandpile monoids on any graph. Finally, we give an explicit combinatorial description of the sandpile group identity for every graph in a family of directed graphs which generalizes the family of (undirected) distance-regular graphs. This family includes many other graphs of interest, including iterated wheels, regular trees, and regular tournaments.Comment: v2: Cleaner presentation, new results in final section. Accepted for publication in J. Combin. Theory Ser. A. 21 pages, 5 figure

    Microwave-assisted synthesis and electrochemical evaluation of VO2 (B) nanostructures

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    Understanding how intercalation materials change during electrochemical operation is paramount to optimizing their behaviour and function and in situ characterization methods allow us to observe these changes without sample destruction. Here we first report the improved intercalation properties of bronze phase vanadium dioxide VO2 (B) prepared by a microwave-assisted route which exhibits a larger electrochemical capacity (232 mAh g-1) compared with VO2 (B) prepared by a solvothermal route (197 mAh g-1). These electrochemical differences have also been followed using in situ X-ray absorption spectroscopy allowing us to follow oxidation state changes as they occur during battery operation

    Comparisons of Three Different Investigative Interview Techniques With Young Children

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    After viewing a film of a mother hitting her son, a film not seen by the college student interviewers, children were misinformed about a detail (via exposure to a misleadingquestion) as well as explicitly coached to disclose 3 false details. The children were then interviewed by interviewers who had previously learned 1 of 3 different interviewing procedures: the Yuille Step-Wise Interview developed by J. C. Yuille, R. Hunter,R. Joffe, & J. Zaparniuk (1993); a doll play interview developed by Action for Child Protection Inc. (1994); or the Modified Structured Interview developed for this study. The Modified Structured Interview yielded more “where” information and was better at detecting if coaching had occurred. However, the interviewers were not very good at discriminating suggested versus coached versus correct witnessed information. The authors found that the deeper one digs for memories, the more one uncovers incorrect versus correct items. They concluded that although the Modified Structured Interview was superior tothe techniques currently in use, cautions are necessary

    Orbital Dimer Model for Spin-Glass State in Y2_2Mo2_2O7_7

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    The formation of a spin glass usually requires both structural disorder and frustrated magnetic interactions. Consequently, the origin of spin-glass behaviour in Y2_2Mo2_2O7_7 - in which magnetic Mo4+^{4+} ions occupy a frustrated pyrochlore lattice with minimal compositional disorder - has been a longstanding question. Here, we use neutron and X-ray pair-distribution function (PDF) analysis to develop a disorder model that resolves apparent incompatibilities between previously-reported PDF, EXAFS and NMR studies and provides a new and physical mechanism for spin-glass formation. We show that Mo4+^{4+} ions displace according to a local "2-in/2-out" rule on each Mo4_4 tetrahedron, driven by orbital dimerisation of Jahn-Teller active Mo4+^{4+} ions. Long-range orbital order is prevented by the macroscopic degeneracy of dimer coverings permitted by the pyrochlore lattice. Cooperative O2^{2-} displacements yield a distribution of Mo-O-Mo angles, which in turn introduces disorder into magnetic interactions. Our study demonstrates experimentally how frustration of atomic displacements can assume the role of compositional disorder in driving a spin-glass transition.Comment: 6 pages, 3 figure

    A MusD Retrotransposon Insertion in the Mouse Slc6a5 Gene Causes Alterations in Neuromuscular Junction Maturation and Behavioral Phenotypes

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    Glycine is the major inhibitory neurotransmitter in the spinal cord and some brain regions. The presynaptic glycine transporter, GlyT2, is required for sustained glycinergic transmission through presynaptic reuptake and recycling of glycine. Mutations in SLC6A5, encoding GlyT2, cause hereditary hyperekplexia in humans, and similar phenotypes in knock-out mice, and variants are associated with schizophrenia. We identified a spontaneous mutation in mouse Slc6a5, caused by a MusD retrotransposon insertion. The GlyT2 protein is undetectable in homozygous mutants, indicating a null allele. Homozygous mutant mice are normal at birth, but develop handling-induced spasms at five days of age, and only survive for two weeks, but allow the study of early activity-regulated developmental processes. At the neuromuscular junction, synapse elimination and the switch from embryonic to adult acetylcholine receptor subunits are hastened, consistent with a presumed increase in motor neuron activity, and transcription of acetylcholine receptors is elevated. Heterozygous mice, which show no reduction in lifespan but nonetheless have reduced levels of GlyT2, have a normal thermal sensitivity with the hot-plate test, but differences in repetitive grooming and decreased sleep time with home-cage monitoring. Open-field and elevated plus-maze tests did not detect anxiety-like behaviors; however, the latter showed a hyperactivity phenotype. Importantly, grooming and hyperactivity are observed in mouse schizophrenia models. Thus, mutations in Slc6a5 show changes in neuromuscular junction development as homozygotes, and behavioral phenotypes as heterozygotes, indicating their usefulness for studies related to glycinergic dysfunction

    The challenge of non-Markovian energy balance models in climate

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    We first review the way in which Hasselmann’s paradigm, introduced in 1976 and recently honored with the Nobel Prize, can, like many key innovations in complexity science, be understood on several different levels. It can be seen as a way to add variability into the pioneering energy balance models (EBMs) of Budyko and Sellers. On a more abstract level, however, it used the original stochastic mathematical model of Brownian motion to provide a conceptual superstructure to link slow climate variability to fast weather fluctuations, in a context broader than EBMs, and led Hasselmann to posit a need for negative feedback in climate modeling. Hasselmann’s paradigm has still much to offer us, but naturally, since the 1970s, a number of newer developments have built on his pioneering ideas. One important one has been the development of a rigorous mathematical hierarchy that embeds Hasselmann-type models in the more comprehensive Mori-Zwanzig generalized Langevin equation (GLE) framework. Another has been the interest in stochastic EBMs with a memory that has slower decay and, thus, longer range than the exponential form seen in his EBMs. In this paper, we argue that the Mori-Kubo overdamped GLE, as widely used in statistical mechanics, suggests the form of a relatively simple stochastic EBM with memory for the global temperature anomaly. We also explore how this EBM relates to Lovejoy et al.’s fractional energy balance equation

    Repository Metadata: Approaches and Challenges

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    Many institutional repositories have pursued a mixed metadata environment, relying on description by multiple workflows. Strategies may include metadata converted from other systems, metadata elicited from the document creator or manager, and metadata created by library or repository staff. Additional editing or proofing may or may not occur. The mixed environment brings challenges of creation, management, and access. In this article, repository efforts at three major universities are discussed. All three repositories run on the DSpace software package, and the opportunities and limitations of that system will be examined. The authors discuss local strategies in light of current thinking on metadata creation, user behavior, and the aggregation of heterogeneous metadata. The contrasts between the mission of each repository effort will show the importance of local customization, while the experience of all three institutions forms the basis for recommendations on strategies of benefit to a wide range of librarians and repository planners

    Effect of COVID-19 vaccination on transmission of Alpha and Delta variants

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    BACKGROUND: Before the emergence of the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), vaccination reduced transmission of SARS-CoV-2 from vaccinated persons who became infected, potentially by reducing viral loads. Although vaccination still lowers the risk of infection, similar viral loads in vaccinated and unvaccinated persons who are infected with the delta variant call into question the degree to which vaccination prevents transmission. METHODS: We used contact-testing data from England to perform a retrospective observational cohort study involving adult contacts of SARS-CoV-2–infected adult index patients. We used multivariable Poisson regression to investigate associations between transmission and the vaccination status of index patients and contacts and to determine how these associations varied with the B.1.1.7 (alpha) and delta variants and time since the second vaccination. RESULTS: Among 146,243 tested contacts of 108,498 index patients, 54,667 (37%) had positive SARS-CoV-2 polymerase-chain-reaction (PCR) tests. In index patients who became infected with the alpha variant, two vaccinations with either BNT162b2 or ChAdOx1 nCoV-19 (also known as AZD1222), as compared with no vaccination, were independently associated with reduced PCR positivity in contacts (adjusted rate ratio with BNT162b2, 0.32; 95% confidence interval [CI], 0.21 to 0.48; and with ChAdOx1 nCoV-19, 0.48; 95% CI, 0.30 to 0.78). Vaccine-associated reductions in transmission of the delta variant were smaller than those with the alpha variant, and reductions in transmission of the delta variant after two BNT162b2 vaccinations were greater (adjusted rate ratio for the comparison with no vaccination, 0.50; 95% CI, 0.39 to 0.65) than after two ChAdOx1 nCoV-19 vaccinations (adjusted rate ratio, 0.76; 95% CI, 0.70 to 0.82). Variation in cycle-threshold (Ct) values (indicative of viral load) in index patients explained 7 to 23% of vaccine-associated reductions in transmission of the two variants. The reductions in transmission of the delta variant declined over time after the second vaccination, reaching levels that were similar to those in unvaccinated persons by 12 weeks in index patients who had received ChAdOx1 nCoV-19 and attenuating substantially in those who had received BNT162b2. Protection in contacts also declined in the 3-month period after the second vaccination. CONCLUSIONS: Vaccination was associated with a smaller reduction in transmission of the delta variant than of the alpha variant, and the effects of vaccination decreased over time. PCR Ct values at diagnosis of the index patient only partially explained decreased transmission. (Funded by the U.K. Government Department of Health and Social Care and others.
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