Generalised Moore spectra in a triangulated category

In this paper we consider a construction in an arbitrary triangulated category T which resembles the notion of a Moore spectrum in algebraic topology. Namely, given a compact object C of T satisfying some finite tilting assumptions, we obtain a functor which "approximates" objects of the module category of the endomorphism algebra of C in T. This generalises and extends a construction of Jorgensen in connection with lifts of certain homological functors of derived categories. We show that this new functor is well-behaved with respect to short exact sequences and distinguished triangles, and as a consequence we obtain a new way of embedding the module category in a triangulated category. As an example of the theory, we recover Keller's canonical embedding of the module category of a path algebra of a quiver with no oriented cycles into its u-cluster category for u>1.Comment: 26 pages, improvement to exposition of the proof of Theorem 3.

Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD).

Background The General Practice Research Database (GPRD) and Doctor's Independent Network Database (DIN), are large electronic primary care databases compiled in the UK during the 1990s. They provide a valuable resource for epidemiological and health services research. GPRD (based on VAMP) presents notes as a series of discrete episodes, whereas DIN is based on a system (MEDITEL) that used a Problem Orientated Medical Record (POMR) which links prescriptions to diagnostic problems. We have examined the implications for research of these different underlying philosophies. Methods Records of 40,183 children from 141 practices in DIN and 76,310 from 464 practices in GRPD who were followed to age 5 were used to compare the volume of recording of prescribing and diagnostic codes in the two databases. To assess the importance and additional value of the POMR within DIN, the appropriateness of diagnostic linking to skin emollient prescriptions was investigated. Results Variation between practices for both the number of days on which prescriptions were issued and diagnoses were recorded was marked in both databases. Mean number of "prescription days" during the first 5 years of life was similar in DIN (19.5) and in GPRD (19.8), but the average number of "diagnostic days" was lower in DIN (15.8) than in GPRD (22.9). Adjustment for linkage increased the average "diagnostic days" to 23.1 in DIN. 32.7% of emollient prescriptions in GPRD appeared with an eczema diagnosis on the same day compared to only 19.4% in DIN; however, 86.4% of prescriptions in DIN were linked to an earlier eczema diagnosis. More specifically 83% of emollient prescriptions appeared under a problem heading of eczema in the 121 practices that were using problem headings satisfactorily. Conclusion Prescribing records in DIN and GPRD are very similar, but the usage of diagnostic codes is more parsimonious in DIN because of its POMR structure. Period prevalence rates will be underestimated in DIN unless this structure is taken into account. The advantage of the POMR is that in 121 of 141 practices using problem headings as intended, most prescriptions can be linked to a problem heading providing a specific reason for their issue

Planetary Phase Variations of the 55 Cancri System

Characterization of the composition, surface properties, and atmospheric conditions of exoplanets is a rapidly progressing field as the data to study such aspects become more accessible. Bright targets, such as the multi-planet 55 Cancri system, allow an opportunity to achieve high signal-to-noise for the detection of photometric phase variations to constrain the planetary albedos. The recent discovery that that inner-most planet, 55 Cancri e, transits the host star introduces new prospects for studying this system. Here we calculate photometric phase curves at optical wavelengths for the system with varying assumptions for the surface and atmospheric properties of 55 Cancri e. We show that the large differences in geometric albedo allows one to distinguish between various surface models, that the scattering phase function cannot be constrained with foreseeable data, and that planet b will contribute significantly to the phase variation depending upon the surface of planet e. We discuss detection limits and how these models may be used with future instrumentation to further characterize these planets and distinguish between various assumptions regarding surface conditions.Comment: 7 pages, 3 figures, accepted for publication in Ap

Progress in the Application of Gas Geochemistry to Geothermal, Tectonic and Magmatic Studies

Gas geochemistry and their associated isotope systematics are developing into powerful tools to understand geological/environmental processes and affirm source origins of geo-fluids. In addition to the traditional noble gas indicators, such as He and Ar, other major and trace gases, including CO2, N2, H2, CH4, CO, Ne, Kr and Xe – abundances and isotopes - have shown considerable application in many fields of the Earth and Environmental Sciences. For example, key constraints on geochemical processes including the degassing history of the solid Earth to form the atmosphere and oceans, the origin and migration characteristics of natural gas, the scale of climate variability, the P-T characteristics of both subaerial and deep water geothermal reservoirs, and the dynamics of the earthquake cycle, are only a few areas where gas geochemistry has been successfully exploited. Following the ‘Frontiers in Gas Geochemistry’ Special Issue in this journal (2013), this volume will reflect this diversity in scope and application of gas geochemistry, focusing on geothermal, tectonic and magmatic studies amenable to the gas geochemistry approach

Weight loss, exercise, or both and physical function in obese older adults

BACKGROUND: Obesity exacerbates the age-related decline in physical function and causes frailty in older adults; however, the appropriate treatment for obese older adults is controversial. METHODS: In this 1-year, randomized, controlled trial, we evaluated the independent and combined effects of weight loss and exercise in 107 adults who were 65 years of age or older and obese. Participants were randomly assigned to a control group, a weightmanagement (diet) group, an exercise group, or a weight-management-plus-exercise (diet–exercise) group. The primary outcome was the change in score on the modified Physical Performance Test. Secondary outcomes included other measures of frailty, body composition, bone mineral density, specific physical functions, and quality of life. RESULTS: A total of 93 participants (87%) completed the study. In the intention-to-treat analysis, the score on the Physical Performance Test, in which higher scores indicate better physical status, increased more in the diet–exercise group than in the diet group or the exercise group (increases from baseline of 21% vs. 12% and 15%, respectively); the scores in all three of those groups increased more than the scores in the control group (in which the score increased by 1%) (P<0.001 for the between-group differences). Moreover, the peak oxygen consumption improved more in the diet–exercise group than in the diet group or the exercise group (increases of 17% vs. 10% and 8%, respectively; P<0.001); the score on the Functional Status Questionnaire, in which higher scores indicate better physical function, increased more in the diet–exercise group than in the diet group (increase of 10% vs. 4%, P<0.001). Body weight decreased by 10% in the diet group and by 9% in the diet–exercise group, but did not decrease in the exercise group or the control group (P<0.001). Lean body mass and bone mineral density at the hip decreased less in the diet–exercise group than in the diet group (reductions of 3% and 1%, respectively, in the diet–exercise group vs. reductions of 5% and 3%, respectively, in the diet group; P<0.05 for both comparisons). Strength, balance, and gait improved consistently in the diet–exercise group (P<0.05 for all comparisons). Adverse events included a small number of exercise-associated musculoskeletal injuries. CONCLUSIONS: These findings suggest that a combination of weight loss and exercise provides greater improvement in physical function than either intervention alone

Oral Health Quality Improvement in the Era of Accountability

The purpose of this report is to review the current status and trends in quality measurement and improvement and describe efforts underway to expand and enhance those efforts. The report will also describe opportunities to use emerging oral health measurement and quality improvement systems to improve and maintain the oral health of the U.S. population

The Primordial Inflation Polarization Explorer (PIPER)

The Primordial Inflation Polarization Explorer (PIPER) is a balloon-borne cosmic microwave background (CMB) polarimeter designed to search for evidence of inflation by measuring the large-angular scale CMB polarization signal. BICEP2 recently reported a detection of B-mode power corresponding to the tensor-to-scalar ratio r = 0.2 on ~2 degree scales. If the BICEP2 signal is caused by inflationary gravitational waves (IGWs), then there should be a corresponding increase in B-mode power on angular scales larger than 18 degrees. PIPER is currently the only suborbital instrument capable of fully testing and extending the BICEP2 results by measuring the B-mode power spectrum on angular scales $\theta$ = ~0.6 deg to 90 deg, covering both the reionization bump and recombination peak, with sensitivity to measure the tensor-to-scalar ratio down to r = 0.007, and four frequency bands to distinguish foregrounds. PIPER will accomplish this by mapping 85% of the sky in four frequency bands (200, 270, 350, 600 GHz) over a series of 8 conventional balloon flights from the northern and southern hemispheres. The instrument has background-limited sensitivity provided by fully cryogenic (1.5 K) optics focusing the sky signal onto four 32x40-pixel arrays of time-domain multiplexed Transition-Edge Sensor (TES) bolometers held at 140 mK. Polarization sensitivity and systematic control are provided by front-end Variable-delay Polarization Modulators (VPMs), which rapidly modulate only the polarized sky signal at 3 Hz and allow PIPER to instantaneously measure the full Stokes vector (I, Q, U, V) for each pointing. We describe the PIPER instrument and progress towards its first flight.Comment: 11 pages, 7 figures. To be published in Proceedings of SPIE Volume 9153. Presented at SPIE Astronomical Telescopes + Instrumentation 2014, conference 915