886 research outputs found
Exercise-induced pulmonary hemorrhage: where are we now?
Citation: Poole, D. C., & Erickson, H. H. (2016). Exercise-induced pulmonary hemorrhage: where are we now? Veterinary Medicine-Research and Reports, 7, 133-148.
https://doi.org/10.2147/vmrr.s120421As the Thoroughbreds race for the final stretch, 44 hooves flash and thunder creating a cacophony of tortured air and turf. Orchestrated by selective breeding for physiology and biomechanics, expressed as speed, the millennia-old symphony of man and beast reaches its climax. At nearly 73 kilometers per hour (45 mph) over half a ton of flesh and bone dwarfs its limpet-like jockey as, eyes wild and nostrils flaring, their necks stretch for glory. Beneath each resplendent livery-adorned, latherin-splattered coat hides a monstrous heart trilling at 4 beats per second, and each minute, driving over 400 L (105 gallons) of oxygen-rich blood from lungs to muscles. Matching breath to stride frequency, those lungs will inhale 16 L (4 gallons) of air each stride moving >1,000 L/min in and out of each nostril - and yet failing. Engorged with blood and stretched to breaking point, those lungs can no longer redden the arterial blood but leave it dusky and cyanotic. Their exquisitely thin blood-gas barrier, a mere 10.5 mu m thick (1/50,000 of an inch), ruptures, and red cells invade the lungs. After the race is won and lost, long after the frenetic crowd has quieted and gone, that blood will clog and inflame the airways. For a few horses, those who bleed extensively, it will overflow their lungs and spray from their nostrils incarnadining the walls of their stall: a horrifically poignant canvas that strikes at horse racing's very core. That exercise-induced pulmonary hemorrhage (EIPH) occurs is a medical and physiological reality. That every reasonable exigency is not taken to reduce/prevent it would be a travesty. This review is not intended to provide an exhaustive coverage of EIPH for which the reader is referred to recent reviews, rather, after a brief reminder of its physiologic and pathologic bases, focus is brought on the latest developments in EIPH discovery as this informs state-of-the-art knowledge, the implementation of that knowledge and recommendations for future research and treatment
The impact of parental involvement and education on academic achievement in elementary school
The academic achievement of students in schools is subject to a variety of factors, many of which are beyond the control of the student. Factors such as parental involvement, parental level of education, and disability all influence the academic achievement and learning of students. The study analyzed nation-wide survey data on students in elementary school and investigates the relationship between student achievement and multiple variables. The variables were parental involvement, and the existence of Autism Spectrum Disorder (ASD) or other disability. Results indicated that students, both ASD and typically developing, have lower parent involvement if they are successful in school
Spitzer IRS Observations of the Galactic Center: Shocked Gas in the Radio Arc Bubble
We present Spitzer IRS spectra (R ~600, 10 - 38 micron) of 38 positions in
the Galactic Center (GC), all at the same Galactic longitude and spanning
plus/minus 0.3 degrees in latitude. Our positions include the Arches Cluster,
the Arched Filaments, regions near the Quintuplet Cluster, the ``Bubble'' lying
along the same line-of-sight as the molecular cloud G0.11-0.11, and the diffuse
interstellar gas along the line-of-sight at higher Galactic latitudes. From
measurements of the [O IV], [Ne II], [Ne III], [Si II], [S III], [S IV], [Fe
II], [Fe III], and H_2 S(0), S(1), and S(2) lines we determine the gas
excitation and ionic abundance ratios. The Ne/H and S/H abundance ratios are ~
1.6 times that of the Orion Nebula. The main source of excitation is
photoionization, with the Arches Cluster ionizing the Arched Filaments and the
Quintuplet Cluster ionizing the gas nearby and at lower Galactic latitudes
including the far side of the Bubble. In addition, strong shocks ionize gas to
O^{+3} and destroy dust grains, releasing iron into the gas phase (Fe/H ~ 1.3
times 10^{-6} in the Arched Filaments and Fe/H ~ 8.8 times 10^{-6} in the
Bubble). The shock effects are particularly noticeable in the center of the
Bubble, but O is present in all positions. We suggest that the shocks
are due to the winds from the Quintuplet Cluster Wolf-Rayet stars. On the other
hand, the H_2 line ratios can be explained with multi-component models of warm
molecular gas in photodissociation regions without the need for H_2 production
in shocks.Comment: 51 pages, 17 figures To be published in the Astrophysical Journa
An Experiential Report on the Thayer Method of Teaching across College-Level Chemistry, Biology, Math, and Physics Courses
The Thayer method of instruction is a little-known active learning technique that dates back to 1817 at the U.S. Military Academy. This study describes the implementation and statistical evaluation of an adaptation of the Thayer method in a variety of college science and math courses. All courses had five characteristics in common: (i) students were given a daily reading schedule and instructed to prepare before class, (ii) each class started with a question and answer session, (iii) class time minimized the use of lecture, (iv) class time maximized the use of active learning, and (v) students were frequently quizzed. A total of 51 sections across chemistry, biology, math, and physics taught by eight professors involving 542 students were used. Students were surveyed at the beginning and the end of the semester on their attitudes toward teaching methods using a 5-point Likert scale. The data were analyzed using the nonparametric Wilcoxon rank-sum test. The results show three outcomes: (i) students prefer the modified Thayer method over a traditional lecture method, (ii) students report feeling more encouraged to stay in college, and (iii) students report no difference in the amount of time that they spend on reading or working on problems. These three results are encouraging amid efforts to educate and retain STEM students. The modified Thayer method should be considered by those using or seeking to use an active learning technique
Early Science with the Large Millimeter Telescope: COOL BUDHIES I - a pilot study of molecular and atomic gas at z~0.2
An understanding of the mass build-up in galaxies over time necessitates
tracing the evolution of cold gas (molecular and atomic) in galaxies. To that
end, we have conducted a pilot study called CO Observations with the LMT of the
Blind Ultra-Deep H I Environment Survey (COOL BUDHIES). We have observed 23
galaxies in and around the two clusters Abell 2192 (z = 0.188) and Abell 963 (z
= 0.206), where 12 are cluster members and 11 are slightly in the foreground or
background, using about 28 total hours on the Redshift Search Receiver (RSR) on
the Large Millimeter Telescope (LMT) to measure the CO J = 1 --> 0
emission line and obtain molecular gas masses. These new observations provide a
unique opportunity to probe both the molecular and atomic components of
galaxies as a function of environment beyond the local Universe. For our sample
of 23 galaxies, nine have reliable detections (S/N3.6) of the CO
line, and another six have marginal detections (2.0 < S/N < 3.6). For the
remaining eight targets we can place upper limits on molecular gas masses
roughly between and . Comparing our results to other
studies of molecular gas, we find that our sample is significantly more
abundant in molecular gas overall, when compared to the stellar and the atomic
gas component, and our median molecular gas fraction lies about above
the upper limits of proposed redshift evolution in earlier studies. We discuss
possible reasons for this discrepancy, with the most likely conclusion being
target selection and Eddington bias.Comment: MNRAS, submitte
Short Communication Reflectance-based detection of oxidizers in ambient air
This study used two types of paper supported materials with a prototype, reflectance-based detector for indication of hydrogen peroxide vapor under ambient laboratory conditions. Titanyl based indicators provide detection through reaction of the indicator resulting in a dosimeter type sensor, while porphyrin based indicators provide a reversible interaction more suitable to continuous monitoring applications. These indicators provide the basis for discussion of characteristics important to design of a sensor system including the application environment and duration, desired reporting frequency, and target specificity
Short Communication Reflectance-based detection of oxidizers in ambient air
This study used two types of paper supported materials with a prototype, reflectance-based detector for indication of hydrogen peroxide vapor under ambient laboratory conditions. Titanyl based indicators provide detection through reaction of the indicator resulting in a dosimeter type sensor, while porphyrin based indicators provide a reversible interaction more suitable to continuous monitoring applications. These indicators provide the basis for discussion of characteristics important to design of a sensor system including the application environment and duration, desired reporting frequency, and target specificity
Hostility Modifies the Association between TV Viewing and Cardiometabolic Risk
Background. It was hypothesized that television viewing is predictive of cardiometabolic risk. Moreover, people with hostile personality type may be more susceptible to TV-induced negative emotions and harmful health habits which increase occurrence of cardiometabolic risk.
Purpose. The prospective association of TV viewing on cardiometabolic risk was examined along with whether hostile personality trait was a modifier.
Methods. A total of 3,269 Black and White participants in the coronary artery risk development in young adults (CARDIA) study were assessed from age 23 to age 35. A cross-lagged panel model at exam years 5, 10, 15, and 20, covering 15 years, was used to test whether hours of daily TV viewing predicted cardiometabolic risk, controlling confounding variables. Multiple group analysis of additional cross-lagged panel models stratified by high and low levels of hostility was used to evaluate whether the association was modified by the hostile personality trait. Results. The cross-lagged association of TV viewing at years 5 and 15 on clustered cardiometabolic risk score at years 10 and 20 was significant (B=0.058 and 0.051), but not at 10 to 15 years. This association was significant for those with high hostility (B=0.068 for exam years 5 to 10 and 0.057 for exam years 15 to 20) but not low hostility. Conclusion. These findings indicate that TV viewing is positively associated with cardiometabolic risk. Further, they indicate that hostility might be a modifier for the association between TV viewing and cardiometabolic risk
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