3,310 research outputs found
Do we need to rethink guidance on repeated interviews?
Within the legal system, children are frequently interviewed about their experiences more than once, with different information elicited in different interviews. The presumed positive and negative effects of multiple interviewing have generated debate and controversy within the legal system and among researchers. Some commentators emphasise that repeated interviews foster inaccurate recall and are inherently suggestive, whereas others emphasise the benefits of allowing witnesses more than one opportunity to recall information. In this article we briefly review the literature on repeated interviewing before presenting a series of cases highlighting what happens when children are interviewed more than once for various reasons. We conclude that, when interviewers follow internationally recognised best-practice guidelines emphasising open-questions and free memory recall, alleged victims of abuse should be interviewed more than once to ensure that more complete accounts are obtained. Implications for current legal guidelines concerning repeated interviewing are discussed
Comparing Simulations and Observations of the Lyman-Alpha Forest I. Methodology
We describe techniques for comparing spectra extracted from cosmological
simulations and observational data, using the same methodology to link
Lyman-alpha properties derived from the simulations with properties derived
from observational data. The eventual goal is to measure the coherence or
clustering properties of Lyman-alpha absorbers using observations of quasar
pairs and groups. We quantify the systematic underestimate in opacity that is
inherent in the continuum fitting process of observed spectra over a range of
resolution and signal-to-noise ratio. We present an automated process for
detecting and selecting absorption features over the range of resolution and
signal-to-noise of typical observational data on the Lyman-alpha "forest".
Using these techniques, we detect coherence over transverse scales out to 500
h^{-1}_{50} kpc in spectra extracted from a cosmological simulation at z = 2.Comment: 52 pages, includes 14 figures, to appear in ApJ v566 Feb 200
Robo-line storage: Low latency, high capacity storage systems over geographically distributed networks
Rapid advances in high performance computing are making possible more complete and accurate computer-based modeling of complex physical phenomena, such as weather front interactions, dynamics of chemical reactions, numerical aerodynamic analysis of airframes, and ocean-land-atmosphere interactions. Many of these 'grand challenge' applications are as demanding of the underlying storage system, in terms of their capacity and bandwidth requirements, as they are on the computational power of the processor. A global view of the Earth's ocean chlorophyll and land vegetation requires over 2 terabytes of raw satellite image data. In this paper, we describe our planned research program in high capacity, high bandwidth storage systems. The project has four overall goals. First, we will examine new methods for high capacity storage systems, made possible by low cost, small form factor magnetic and optical tape systems. Second, access to the storage system will be low latency and high bandwidth. To achieve this, we must interleave data transfer at all levels of the storage system, including devices, controllers, servers, and communications links. Latency will be reduced by extensive caching throughout the storage hierarchy. Third, we will provide effective management of a storage hierarchy, extending the techniques already developed for the Log Structured File System. Finally, we will construct a protototype high capacity file server, suitable for use on the National Research and Education Network (NREN). Such research must be a Cornerstone of any coherent program in high performance computing and communications
A multi-method approach to radial-velocity measurement for single-object spectra
The derivation of radial velocities from large numbers of spectra that
typically result from survey work, requires automation. However, except for the
classical cases of slowly rotating late-type spectra, existing methods of
measuring Doppler shifts require fine-tuning to avoid a loss of accuracy due to
the idiosyncrasies of individual spectra. The radial velocity spectrometer
(RVS) on the Gaia mission, which will start operating very soon, prompted a new
attempt at creating a measurement pipeline to handle a wide variety of spectral
types.
The present paper describes the theoretical background on which this software
is based. However, apart from the assumption that only synthetic templates are
used, we do not rely on any of the characteristics of this instrument, so our
results should be relevant for most telescope-detector combinations.
We propose an approach based on the simultaneous use of several alternative
measurement methods, each having its own merits and drawbacks, and conveying
the spectral information in a different way, leading to different values for
the measurement. A comparison or a combination of the various results either
leads to a "best estimate" or indicates to the user that the observed spectrum
is problematic and should be analysed manually.
We selected three methods and analysed the relationships and differences
between them from a unified point of view; with each method an appropriate
estimator for the individual random error is chosen. We also develop a
procedure for tackling the problem of template mismatch in a systematic way.
Furthermore, we propose several tests for studying and comparing the
performance of the various methods as a function of the atmospheric parameters
of the observed objects. Finally, we describe a procedure for obtaining a
knowledge-based combination of the various Doppler-shift measurements.Comment: 16 pages, 4 figure
Characterising the tumour morphological response to therapeutic intervention:an ex vivo model
In cancer, morphological assessment of histological tissue samples is a fundamental part of both diagnosis and prognosis. Image analysis offers opportunities to support that assessment through quantitative metrics of morphology. Generally, morphometric analysis is carried out on two dimensional tissue section data and so only represents a small fraction of any tumour. We present a novel application of three-dimensional (3D) morphometrics for 3D imaging data obtained from tumours grown in a culture model. Minkowski functionals, a set of measures that characterise geometry and topology in n-dimensional space, are used to quantify tumour topology in the absence of and in response to therapeutic intervention. These measures are used to stratify the morphological response of tumours to therapeutic intervention. Breast tumours are characterised by estrogen receptor (ER) status, human epidermal growth factor receptor (HER)2 status and tumour grade. Previously, we have shown that ER status is associated with tumour volume in response to tamoxifen treatment ex vivo. Here, HER2 status is found to predict the changes in morphology other than volume as a result of tamoxifen treatment ex vivo. Finally, we show the extent to which Minkowski functionals might be used to predict tumour grade.Minkowski functionals are generalisable to any 3D data set, including in vivo and cellular systems. This quantitative topological analysis can provide a valuable link among biomarkers, drug intervention and tumour morphology that is complementary to existing, non-morphological measures of tumour response to intervention and could ultimately inform patient treatment
Predictors of Depressive Symptomatology in Family Caregivers of Wom-en With Substance Use Disorders or Co-Occurring Substance Use and Mental Disorders
This study utilized a stress-process model to examine the impact of having a female family member with substance use or co-occurring substance use and mental disorders on family caregivers\u27 depressive symptomatology. Participants were 82 women receiving substance abuse treatment and the family member providing the most social support for each woman. Greater caregiver depressive symptomatology was predicted by greater care recipient emotional problems, less care recipient social support, and poor caregiver health. Implications of findings for treatment and future research are discusse
A network-based ranking system for American college football
American college football faces a conflict created by the desire to stage
national championship games between the best teams of a season when there is no
conventional playoff system to decide which those teams are. Instead, ranking
of teams is based on their record of wins and losses during the season, but
each team plays only a small fraction of eligible opponents, making the system
underdetermined or contradictory or both. It is an interesting challenge to
create a ranking system that at once is mathematically well-founded, gives
results in general accord with received wisdom concerning the relative
strengths of the teams, and is based upon intuitive principles, allowing it to
be accepted readily by fans and experts alike. Here we introduce a
one-parameter ranking method that satisfies all of these requirements and is
based on a network representation of college football schedules.Comment: 15 pages, 3 figure
Mechanism of CSF outflow through human arachnoid granulations using in-vitro and ex-vivo perfusion models
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