Mliječni obroci hospitalizirane djece kao izvor energije, kalcija i fosfora u zadovoljenju njihovih dnevnih potreba

A dairy meal is defined as a specific food serving composed from milk and dairy products. Because of its nutritional value and complex chemical composition, milk and dairy products play an important role in the diet of children and represent a rich source of calcium, phosphorus, as well as valuable proteins, B vitamins and minerals. Healthy children should consume at least three servings of dairy products daily, which contributes to the total energy and nutrients that children need. The needs of an unhealthy child are often higher than those who are healthy and depend on the state of the body. The aim of this study was to determine the incidence of consumption of dairy meals in hospitalized children and to find out if their energy needs, as well as their need for calcium and phosphorus through the consumption of the same were met. Significant differences were found between recommended energy intake from dairy products and actual energy intake from consumed milk and dairy products in three Croatian regions (P=0.021) tested. The highest values were recorded in central Croatia (253 Kcal or 34.4 %) and the lowest in the northern Croatian coastal region (17.05 Kcal or 20.1 %), which indicates a greater representation of milk and dairy meals in children’s daily menu. Furthermore, hospitalized children meet almost half of their recommended daily intake of calcium and phosphorus from dairy meals for all three regions. The highest rate was found in central Croatia, 48.7 % or 400 mg of calcium, respectively 42.9 % or 322.69 mg phosphorus, while the remaining portion of calcium and phosphorus originates from different rich non-dairy food sources. In all regions the most common forms of dairy foods consumed were milk and dairy desserts.Mliječni obrok definira se kao točno određeno serviranje namirnice iz skupine mlijeka i mliječnih proizvoda. Zbog svoje nutritivne vrijednosti i složenog kemijskog sastava, mlijeko i mliječni proizvodi imaju važnu ulogu u prehrani djece. Bogat su izvor kalcija i fosfora te visokovrijednih bjelančevina, vitamina B skupine i mineralnih tvari. Zdrava djeca trebala bi konzumirati najmanje 3 serviranja mlijeka i mliječnih proizvoda dnevno što doprinosi ukupnom zadovoljenju energijskih i nutritivnih potreba, dok su potrebe oboljelog djeteta i veće ovisno o stanju organizma. Cilj ovog istraživanja bio je utvrditi zastupljenost mliječnih obroka u hospitalizirane djece i zadovoljenje energijskih potreba te potreba za kalcijem i fosforom kroz konzumaciju istih. Između unesene i preporučene energije iz mlijeka u tri ispitivane regije utvrđene su značajne razlike (P=0,021). Najveće vrijednosti zabilježene su u Središnjoj Hrvatskoj (253 Kcal ili 34,4 %), a najmanje u Sjevernom hrvatskom primorju (17,05 Kcal ili 20,1 %), što ukazuje na veću zastupljenost mliječnog obroka u dnevnom jelovniku, a time i veće zadovoljenje potreba za energijom iz mlijeka. Nadalje, hospitalizirana djeca zadovoljavaju gotovo polovicu preporučenog dnevnog unosa kalcija i fosfora iz mliječnih obroka i to u svim regijama, a najviši postotak zadovoljenja je u Središnjoj Hrvatskoj, i to 48,7 % ili 400 mg kalcija, odnosno 42,9 % ili 322,69 mg fosfora, dok je preostali udio kalcija i fosfora porijeklom iz različitih bogatih nemliječnih prehrambenih izvora. Među regijama, najčešći konzumirani oblici mliječnih namirnica bili su konzumna mlijeka i mliječni deserti

Abernethy malformation as a rare indication for liver transplantation: Case report

Abernethyjeva malformacija ili kongenitalna ageneza portalne vene (KAPV) rijetka je malformacija abdominalnoga splanhničkog venskog sustava. Dijagnoza se najčešće postavlja u dječjoj dobi i često je povezana s drugim malformacijama poput srčanih grešaka i poremećaja skeletnog sustava, kao i s tumorima jetre. Sama malformacija može se manifestirati u dva oblika. Kod tipa I portalna krv potpuno zaobilazi jetru te se gornja mezenterijska vena i lijenalna vena odvojeno (tip Ia) ili zajedno (tip Ib) dreniraju u donju šuplju venu, a u jetri ne postoje intrahepatalni portalni venski ogranci. Kod tipa II prisutan je parcijalni portokavalni shunt i portalna krv djelomično opskrbljuje jetru. Nema jedinstvenoga terapijskog pristupa za sve bolesnike s Abernethyjevom malformacijom, međutim, kod bolesnika sa simptomima jetrene bolesti (encefalopatija, loša funkcija jetre) te onih s tumorima jetre preporučuje se transplantacija jetre. U ovom radu prikazujemo Abernethyjevu malformaciju tipa Ib u 17-godišnje bolesnice kod koje se obradom kronične malaksalosti praćene bolima pod desnim rebrenim lukom pronašao neresektabilni tumor jetre te joj je uspješno obavljena ortotopna transplantacija jetre.Abernethy malformation or congenital agenesis of the portal vein (CAPV) is a rare malformation of the abdominal splanchnic venous system. This malformation is commonly found in children and is often associated with other malformations such as congenital cardiac anomalies and skeletal system disorders, as well as liver tumors. There are two types of Abernethy malformation. In type I, portal blood bypasses the liver completely, with the superior mesenteric vein and the splenic vein draining into the inferior vena cava separately (type Ia), or together (type Ib). There are no intrahepatic portal vein branches in the liver. Type II is a partial portocaval shunt in which portal blood partially supplies the liver. There is no unified therapeutic approach for all patients with Abernethy malformation, however, liver transplantation is recommended in patients with liver disease (encephalopathy, poor liver function) and those with liver tumors. In this case report we present a case of Abernethy type Ib malformation in a 17-year-old patient with chronic malaise and uper abdominal pain. During diagnostic work-up, an unresectable liver tumor was found and the patient was successfully treated with orthotopic liver transplantation

Ružička days : International conference 16th Ružička Days “Today Science – Tomorrow Industry” : Proceedings

Proceedings contains articles presented at Conference divided into sections: open lecture (1), chemical analysis and synthesis (3), chemical and biochemical engineering (8), food technology and biotechnology (8), medical chemistry and pharmacy (3), environmental protection (11) and meeting of young chemists (2)

Dietary Sources of Vitamin D, Vitamin D Supplementation, and Its Bio-Viability

The focus of this paper is to review the data on the dietary sources of vitamin D, vitamin D supplementation and its bio-viability. Vitamin D is a fat-soluble vitamin that plays an important role in human health. Low vitamin D levels (<75 nmol/l) have been reported worldwide in all age groups in recent years. Vitamin D deficiency is rising, mainly due to modern lifestyle and malabsorption disorders. There are two main sources of vitamin D; dietary source which includes food of animal and plant origin as well as dietary supplements and endogenous synthesis under the UVB radiation in the skin. Dietary sources rich in vitamin D are mainly fish oil, sea fish, eggs, and margarines fortified with vitamin D. As the adequate intake of vitamin D is hard to achieve through the diet alone, dietary supplements of vitamin D are recommended. However, there are different factors influencing the bioavailability of vitamin D and are explained within this review article. There is no universal consent on the amount and the frequency of vitamin D supplementation. Furthermore, there is still missing information for better understanding the vitamin D absorption, bioavailability, and metabolism in human. Conclusion – A brief mini review article on vitamin D summarizes the current knowledge about dietary sources of vitamin D, vitamin D supplements, and its bio-viability. The best source of vitamin D is in vivo synthesis in the skin under the UVB radiation. The main dietary sources of vitamin D includes food of animal and plant origin. Adequate intake of vitamin D through the diet alone is hard to achieve, therefore vitamin D supplementation is recommended

Ružička days : International conference 18th Ružička Days “Today Science – Tomorrow Industry” : Proceedings

Proceedings contains articles presented at Conference divided into sections: chemical analysis and synthesis, chemical and biochemical engineering, food technology and biotechnology, medical chemistry and pharmacy, environmental protection and meeting of young chemists

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research