11 research outputs found
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate Degu
- Abate Degu
- Abate Kalkidan Hassell
- Abate Kalkidan Hassell
- Abbafati Cristiana
- Abbafati Cristiana
- Abbasi Nooshin
- Abbasi Nooshin
- Abbastabar Hedayat
- Abbastabar Hedayat
- Abd-Allah Foad
- Abd-Allah Foad
- Abdela Jemal
- Abdela Jemal
- Abdelalim Ahmed
- Abdelalim Ahmed
- Abdollahpour Ibrahim
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abdulkader Rizwan Suliankatchi
- Abebe Molla
- Abebe Molla
- Abebe Zegeye
- Abebe Zegeye
- Abera Semaw F.
- Abera Semaw F.
- Abil Olifan Zewdie
- Abil Olifan Zewdie
- Abraha Haftom Niguse
- Abraha Haftom Niguse
- Abrham Aklilu Roba
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen M. E.
- Abu-Rmeileh Niveen M. E.
- Accrombessi Manfred Mario Kokou
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Dilaram
- Acharya Pawan
- Acharya Pawan
- Adamu Abdu A.
- Adamu Abdu A.
- Adane Akikw Awoke
- Adane Akikw Awoke
- Adebayo Oladimeji M.
- Adebayo Oladimeji M.
- Adedoyin Rufus Adesoji
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Adekanmbi Victor
- Ademi Zanfina
- Ademi Zanfina
- Adetokunboh Olatunji
- Adetokunboh Olatunji
- Adib Mina G.
- Adib Mina G.
- Admasie Amha
- Admasie Amha
- Adsuar Jose C.
- Adsuar Jose C.
- Afanvi Kossivi Agbelenko
- Afanvi Kossivi Agbelenko
- Afarideh Mohsen
- Afarideh Mohsen
- Afshin Ashkan
- Afshin Ashkan
- Agarwal Gina
- Agarwal Gina
- Aggarwal Anju
- Aggarwal Anju
- Aghayan Sargis Aghast
- Aghayan Sargis Aghast
- Agrawal Anurag
- Agrawal Anurag
- Agrawal Sutapa
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aichour Miloud Taki Eddine
- Akbari Mohammad Esmaeil
- Akbari Mohammad Esmaeil
- Akinyemiju Tomi
- Akinyemiju Tomi
- Akseer Nadia
- Akseer Nadia
- Al-Aly Ziyad
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Eyadhy Ayman
- Al-Mekhlafi Hesham M.
- Al-Mekhlafi Hesham M.
- Alam Khurshid
- Alam Khurshid
- Alam Samiah
- Alam Samiah
- Alam Tahiya
- Alam Tahiya
- Alandab Fares
- Alandab Fares
- Alashi Alaa
- Alashi Alaa
- Alavian Seyed Moayed
- Alavian Seyed Moayed
- Alene Kefyalew Addis
- Alene Kefyalew Addis
- Ali Komal
- Ali Komal
- Ali Syed Mustafa
- Ali Syed Mustafa
- Alijanzadeh Mehran
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alkerwi Ala'a
- Alla Francois
- Alla Francois
- Alsharif Ubai
- Alsharif Ubai
- Altirkawi Khalid
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Amare Azmeraw T.
- Amlov Johan
- Amlov Johan
- Ammar Walid
- Ammar Walid
- Anber Nahla Hamed
- Anber Nahla Hamed
- Anderson Jason A.
- Anderson Jason A.
- Andrei Catalina Liliana
- Andrei Catalina Liliana
- Androudi Sofia
- Androudi Sofia
- Anh Quynh Nguyen
- Anh Quynh Nguyen
- Animut Megbaru Debalkie
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Anjomshoa Mina
- Ansha Mustafa Geleto
- Ansha Mustafa Geleto
- Anto Josep M.
- Anto Josep M.
- Antonio Carl Abelardo T.
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Anwari Palwasha
- Appiah Lambert Tetteh
- Appiah Lambert Tetteh
- Appiah Seth Christopher Yaw
- Appiah Seth Christopher Yaw
- Arabloo Jalal
- Arabloo Jalal
- Aremu Olatunde
- Aremu Olatunde
- Artaman Al
- Artaman Al
- Aryal Krishna K.
- Aryal Krishna K.
- Asayesh Hamid
- Asayesh Hamid
- Ataro Zerihun
- Ataro Zerihun
- Ausloos Marcel
- Ausloos Marcel
- Avokpaho Euripide F. G. A.
- Avokpaho Euripide F. G. A.
- Awasthi Ashish
- Awasthi Ashish
- Ayer Rakesh
- Ayer Rakesh
- Ayuk Tanabe B.
- Ayuk Tanabe B.
- Azzopardi Peter S.
- Azzopardi Peter S.
- Babazadeff Arefeh
- Babazadeff Arefeh
- Badali Hamid
- Badali Hamid
- Badawi Alaa
- Badawi Alaa
- Balakrishnan Kalpana
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Bali Ayele Geleto
- Ball Kylie
- Ball Kylie
- Ballesteros Wayra Citlali Paz
- Ballesteros Wayra Citlali Paz
- Bamighausen Till Winfried
- Bamighausen Till Winfried
- Banach Maciej
- Banach Maciej
- Banoub Joseph Adel Mattar
- Banoub Joseph Adel Mattar
- Barac Aleksandra
- Barac Aleksandra
- Barker-Collo Suzanne Lyn
- Barker-Collo Suzanne Lyn
- Barrero Lope H.
- Barrero Lope H.
- Basu Sanjay
- Basu Sanjay
- Baune Bernhard T.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Bedi Neeraj
- Beghi Ettore
- Beghi Ettore
- Behzadifar Masoud
- Behzadifar Masoud
- Behzadifar Meysam
- Behzadifar Meysam
- Bejoy Yannick
- Bejoy Yannick
- Bekele Bayu Begashaw
- Bekele Bayu Begashaw
- Bekru Fyasu Tamru
- Bekru Fyasu Tamru
- Belay Ezra
- Belay Ezra
- Belay Yilhalem Abebe
- Belay Yilhalem Abebe
- Bell Michelle L.
- Bell Michelle L.
- Bellew Shoshana H.
- Bellew Shoshana H.
- Bello Aminu K.
- Bello Aminu K.
- Bemabe Eduardo
- Bemabe Eduardo
- Bemstein Robert S.
- Bemstein Robert S.
- Bennett Derrick A.
- Bennett Derrick A.
- Bensenor Isabela M.
- Bensenor Isabela M.
- Bergeron Gilles
- Bergeron Gilles
- Berhane Adugnaw
- Berhane Adugnaw
- Beuran Mircea
- Beuran Mircea
- Beyranvand Tina
- Beyranvand Tina
- Bhala Neeraj
- Bhala Neeraj
- Bhalla Ashish
- Bhalla Ashish
- Bhattarai Suraj
- Bhattarai Suraj
- Bhutta Zulfiqar A.
- Bhutta Zulfiqar A.
- Biadgo Belete
- Biadgo Belete
- Bicer Burcu Kucuk
- Bicer Burcu Kucuk
- Bijani Ali
- Bijani Ali
- Bikbov Boris
- Bikbov Boris
- Bilano Ver
- Bilano Ver
- Bililign Nigus
- Bililign Nigus
- Bin Sayeed Muhamad Shandaat
- Bin Sayeed Muhamad Shandaat
- Bin Zaman Sojib
- Bin Zaman Sojib
- Bisanzio Donal
- Bisanzio Donal
- Biswas Tuhin
- Biswas Tuhin
- Bjorge Tone
- Bjorge Tone
- Blacker Brigette F.
- Blacker Brigette F.
- Bleyer Archie
- Bleyer Archie
- Borschmann Rohan
- Borschmann Rohan
- Bou-Orm Ibrahim R.
- Bou-Orm Ibrahim R.
- Boufous Soufiane
- Boufous Soufiane
- Bourne Rupert
- Bourne Rupert
- Brady Oliver J.
- Brady Oliver J.
- Brauer Michael
- Brauer Michael
- Brazinova Alexandra
- Brazinova Alexandra
- Breitborde Nicholas J. K.
- Breitborde Nicholas J. K.
- Brenner Hermann
- Brenner Hermann
- Briko Andrey Nikolaevich
- Briko Andrey Nikolaevich
- Britton Gabrielle
- Britton Gabrielle
- Brugha Traolach
- Brugha Traolach
- Buchbindet Rachelle
- Buchbindet Rachelle
- Burnett Richard T.
- Burnett Richard T.
- Busse Reinhard
- Busse Reinhard
- Butt Zahid A.
- Butt Zahid A.
- Cahill Leah E.
- Cahill Leah E.
- Cahuana-Hurtado Lucero
- Cahuana-Hurtado Lucero
- Campos-Nonato Ismael R.
- Campos-Nonato Ismael R.
- Car Lorainne Tudor
- Car Lorainne Tudor
- Cardenas Rosario
- Cardenas Rosario
- Carreras Giulia
- Carreras Giulia
- Carrero Juan J.
- Carrero Juan J.
- Carvalho Felix
- Carvalho Felix
- Castaneda-Orjuela Carlos A.
- Castaneda-Orjuela Carlos A.
- Castro Franz
- Castro Franz
- Catala-Lopez Ferran
- Catala-Lopez Ferran
- Causey Kate
- Causey Kate
- Cercy Kelly M.
- Cercy Kelly M.
- Cerin Ester
- Cerin Ester
- Chaiah Yazan
- Chaiah Yazan
- Chang Hying-Ti
- Chang Hying-Ti
- Chang Jung-Chen
- Chang Jung-Chen
- Chang Kai-Lan
- Chang Kai-Lan
- Charlson Fiona J.
- Charlson Fiona J.
- Chattopadhyay Aparajita
- Chattopadhyay Aparajita
- Chattu Vijay Kumar
- Chattu Vijay Kumar
- Chee Miao Li
- Chee Miao Li
- Cheng Ching-Yu
- Cheng Ching-Yu
- Chew Adrienne
- Chew Adrienne
- Chiang Peggy Pei-Chia
- Chiang Peggy Pei-Chia
- Chimed-Ochir Odgerel
- Chimed-Ochir Odgerel
- Chin Ken Lee
- Chin Ken Lee
- Chitheer Abdulaal
- Chitheer Abdulaal
- Choi Jee-Young J.
- Choi Jee-Young J.
- Chowdhury Rajiv
- Chowdhury Rajiv
- Christensen Hanne
- Christensen Hanne
- Christopher Devasahayam J.
- Christopher Devasahayam J.
- Chung Sheng-Chia
- Chung Sheng-Chia
- Cicuttini Flavia M.
- Cicuttini Flavia M.
- Cohen Aaron J.
- Cohen Aaron J.
- Collado-Mateo Daniel
- Collado-Mateo Daniel
- Cooper Cyrus
- Cooper Cyrus
- Cooper Owen R.
- Cooper Owen R.
- Coresh Josef
- Coresh Josef
- Cornaby Leslie
- Cornaby Leslie
- Cortesi Paolo Angelo
- Cortesi Paolo Angelo
- Cortinovis Monica
- Cortinovis Monica
- Costa Megan
- Costa Megan
- Cousin Ewerton
- Cousin Ewerton
- Criqui Michael H.
- Criqui Michael H.
- Cromwell Elizabeth A.
- Cromwell Elizabeth A.
- Cundiff David K.
- Cundiff David K.
- Daba Alenmeh Kabeta
- Daba Alenmeh Kabeta
- Dachew Berihun Assefa
- Dachew Berihun Assefa
- Dadi Abel Fekadu
- Dadi Abel Fekadu
- Damasceno Alberti Antonio Moura
- Damasceno Alberti Antonio Moura
- Dandona Lalit
- Dandona Lalit
- Dandona Rakhi
- Dandona Rakhi
- Darby Sarah C.
- Darby Sarah C.
- Dargan Paul I.
- Dargan Paul I.
- Daryani Ahmed
- Daryani Ahmed
- Das Gupta Rajat
- Das Gupta Rajat
- Das Neves Jose
- Das Neves Jose
- Dasa Tamirat Tesfaye
- Dasa Tamirat Tesfaye
- Dash Aditya Prasad
- Dash Aditya Prasad
- Davitoiu Dragos Virgil
- Davitoiu Dragos Virgil
- Davletov Kairat
- Davletov Kairat
- De la Cruz-Gongora Vanessa
- De la Cruz-Gongora Vanessa
- De la Hoz Fernando Pio
- De la Hoz Fernando Pio
- De Leo Diego
- De Leo Diego
- De Neve Jan-Walter
- De Neve Jan-Walter
- Defo Barthelemy Kuate
- Defo Barthelemy Kuate
- Degenhardt Louisa
- Degenhardt Louisa
- Deiparine Selina
- Deiparine Selina
- Dellavalle Robert P.
- Dellavalle Robert P.
- Demoz Gebre Teklemariam
- Demoz Gebre Teklemariam
- Denova-Gutierrez Edgar
- Denova-Gutierrez Edgar
- Deribe Kebede
- Deribe Kebede
- Dervenis Nikolaos
- Dervenis Nikolaos
- Deshpande Aniruddha
- Deshpande Aniruddha
- Dessie Getenet Ayalew
- Dessie Getenet Ayalew
- Deveber Gabrielle Aline
- Deveber Gabrielle Aline
- Dey Subhojit
- Dey Subhojit
- Dharmaratne Samath Dhamminda
- Dharmaratne Samath Dhamminda
- Dhimal Meghnath
- Dhimal Meghnath
- Dinberu Mesfin Tadese
- Dinberu Mesfin Tadese
- Ding Eric L.
- Ding Eric L.
- Diro Helen Derara
- Diro Helen Derara
- Djalalinia Shirin
- Djalalinia Shirin
- Dokova Klara
- Dokova Klara
- Doku David Teye
- Doku David Teye
- Driscoll Tim R.
- Driscoll Tim R.
- Dubey Manisha
- Dubey Manisha
- Dubljanin Eleonora
- Dubljanin Eleonora
- Duken Eyasu Ejeta
- Duken Eyasu Ejeta
- Duncan Bruce B.
- Duncan Bruce B.
- Duraes Andre R.
- Duraes Andre R.
- Ebert Natalie
- Ebert Natalie
- Ebrahimi Hedyeh
- Ebrahimi Hedyeh
- Ebrahimpour Soheil
- Ebrahimpour Soheil
- Edvardsson David
- Edvardsson David
- Eggen Anne Elise
- Eggen Anne Elise
- El Bcheraoui Charbel
- El Bcheraoui Charbel
- El-Khatib Iad
- El-Khatib Iad
- Elfiong Andem
- Elfiong Andem
- Elyazar Iqbal Rf
- Elyazar Iqbal Rf
- Enayati Ahmadali
- Enayati Ahmadali
- Endries Aman Yesuf
- Endries Aman Yesuf
- Er Benjamin
- Er Benjamin
- Erskine Holly E.
- Erskine Holly E.
- Eskandarieh Sharareh
- Eskandarieh Sharareh
- Esteghamati Alireza
- Esteghamati Alireza
- Estep Kara
- Estep Kara
- Fakhim Hamed
- Fakhim Hamed
- Falavarjani Khalil Ghasemi
- Falavarjani Khalil Ghasemi
- Faramarzi Mahbobeh
- Faramarzi Mahbobeh
- Fareed Mohammad
- Fareed Mohammad
- Farid Talha A.
- Farid Talha A.
- Farinha Carla Sofia E. Sa
- Farinha Carla Sofia E. Sa
- Farioli Andrea
- Farioli Andrea
- Faro Andre
- Faro Andre
- Farvid Maryam S.
- Farvid Maryam S.
- Farzaei Mohammad Hosein
- Farzaei Mohammad Hosein
- Fatima Batool
- Fatima Batool
- Fay Kairsten A.
- Fay Kairsten A.
- Fazaeli Ali Akbar
- Fazaeli Ali Akbar
- Feigin Valery L.
- Feigin Valery L.
- Feigl Andrea B.
- Feigl Andrea B.
- Fereshtehnejad Seyed-Mohammad
- Fereshtehnejad Seyed-Mohammad
- Fernandes Eduarda
- Fernandes Eduarda
- Fernandes Joao C.
- Fernandes Joao C.
- Ferrara Giannina
- Ferrara Giannina
- Ferrari Alize J.
- Ferrari Alize J.
- Ferreira Manuela L.
- Ferreira Manuela L.
- Filip Irina
- Filip Irina
- Finger Jonas David
- Finger Jonas David
- Fischer Florian
- Fischer Florian
- Foigt Nataliya A.
- Foigt Nataliya A.
- Foreman Kyle J.
- Foreman Kyle J.
- Fukumoto Takeshi
- Fukumoto Takeshi
- Fullman Nancy
- Fullman Nancy
- Furst Thomas
- Furst Thomas
- Furtado Joao M.
- Furtado Joao M.
- Futran Neal D.
- Futran Neal D.
- Gakidou Emmanuela
- Gakidou Emmanuela
- Gall Seana
- Gall Seana
- Gallus Silvan
- Gallus Silvan
- Gamkrelidze Amiran
- Gamkrelidze Amiran
- Ganji Morsaleh
- Ganji Morsaleh
- Garcia-Basteiro Alberto L.
- Garcia-Basteiro Alberto L.
- Gardner William Ni
- Gardner William Ni
- Gebre Abadi Kahsu
- Gebre Abadi Kahsu
- Gebremedhin Amanuel Tesfay
- Gebremedhin Amanuel Tesfay
- Gebremichael Teklu Gebrehiwo
- Gebremichael Teklu Gebrehiwo
- Geese Kebede Embaye
- Geese Kebede Embaye
- Gelano Tilayie Feto
- Gelano Tilayie Feto
- Geleijnse Johanna M.
- Geleijnse Johanna M.
- Geramo Yilma Chisha Dea
- Geramo Yilma Chisha Dea
- Gething Peter W.
- Gething Peter W.
- Ghadimi Reza
- Ghadimi Reza
- Ghadiri Keyghobad
- Ghadiri Keyghobad
- Ghasemi-Kasman Maryam
- Ghasemi-Kasman Maryam
- Ghimire Mamata
- Ghimire Mamata
- Ghosh Rakesh
- Ghosh Rakesh
- Ghoshal Aloke Gopal
- Ghoshal Aloke Gopal
- Giampaoli Simona
- Giampaoli Simona
- Gill Paramjit Singh
- Gill Paramjit Singh
- Gill Tiffany K.
- Gill Tiffany K.
- Gillum Richard F.
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageed
- Ginawi Ibrahim Abdelmageed
- Giussani Giorgia
- Giussani Giorgia
- Gnedovskaya Elena V.
- Gnedovskaya Elena V.
- Godwin William W.
- Godwin William W.
- Goli Srinivas
- Goli Srinivas
- Gomez-Dantes Hector
- Gomez-Dantes Hector
- Gona Philimon N.
- Gona Philimon N.
- Gopalani Sameer Vali
- Gopalani Sameer Vali
- Goulart Alessandra C.
- Goulart Alessandra C.
- Grada Ayman
- Grada Ayman
- Grams Morgan E.
- Grams Morgan E.
- Grillo Massimo
- Grillo Massimo
- Grosso Giuseppe
- Grosso Giuseppe
- Gugnani Hanish Chander
- Gugnani Hanish Chander
- Guo Yuming
- Guo Yuming
- Gupta Rahul
- Gupta Rahul
- Gupta Rajeev
- Gupta Rajeev
- Gupta Tanush
- Gupta Tanush
- Gutierrez Reyna Alma
- Gutierrez Reyna Alma
- Gutierrez-Torres Daniela S.
- Gutierrez-Torres Daniela S.
- Ha Thu Nguyen
- Ha Thu Nguyen
- Ha Howard
- Ha Howard
- Haagsma Juanita A.
- Haagsma Juanita A.
- Habtewold Tesfa Dejenie
- Habtewold Tesfa Dejenie
- Hachinski Vladimir
- Hachinski Vladimir
- Hafezi-Nejad Nima
- Hafezi-Nejad Nima
- Hagos Tekleberhan B.
- Hagos Tekleberhan B.
- Hai Quang Pham
- Hai Quang Pham
- Hailegiyorgis Tewodros Tesfa
- Hailegiyorgis Tewodros Tesfa
- Hailu Gessessew Bugssa
- Hailu Gessessew Bugssa
- Haj-Mirzaian Arvin
- Haj-Mirzaian Arvin
- Haj-Mirzaian Arya
- Haj-Mirzaian Arya
- Hamadeh Randah R.
- Hamadeh Randah R.
- Hamidi Samer
- Hamidi Samer
- Handal Alexis J.
- Handal Alexis J.
- Hankey Graeme J.
- Hankey Graeme J.
- Harb Hilda L.
- Harb Hilda L.
- Harikrishnan Sivadasanpillai
- Harikrishnan Sivadasanpillai
- Haro Josep Maria
- Haro Josep Maria
- Hassankhani Hadi
- Hassankhani Hadi
- Hassen Hamid Yimam
- Hassen Hamid Yimam
- Havmoeller Rasmus
- Havmoeller Rasmus
- Hawley Caitlin N.
- Hawley Caitlin N.
- Hay Simon I.
- Hay Simon I.
- Hedayatizadeh-Omran Akbar
- Hedayatizadeh-Omran Akbar
- Heibati Behzad
- Heibati Behzad
- Heidari Behnam
- Heidari Behnam
- Heidari Mohsen
- Heidari Mohsen
- Hendrie Delia
- Hendrie Delia
- Henok Andualem
- Henok Andualem
- Heredia-Pi Ileana
- Heredia-Pi Ileana
- Herteliu C.
- Herteliu C.
- Herteliu C.
- Herteliu C.
- Heydarpour Fatemeh
- Heydarpour Fatemeh
- Heydarpour Sousan
- Heydarpour Sousan
- Hibstu Desalegn T.
- Hibstu Desalegn T.
- Higazi Tarig B.
- Higazi Tarig B.
- Hilawe Esayas Haregot
- Hilawe Esayas Haregot
- Hoek Hans W.
- Hoek Hans W.
- Hoffiman Howard J.
- Hoffiman Howard J.
- Hole Michael K.
- Hole Michael K.
- Hoogar Praveen
- Hoogar Praveen
- Hosgood H. Dean
- Hosgood H. Dean
- Hosseini Seyed Mostafa
- Hosseini Seyed Mostafa
- Hosseinzadeh Mehdi
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Mihaela
- Hostiuc Sorin
- Hostiuc Sorin
- Hoy Damian G.
- Hoy Damian G.
- Hsairi Mohamed
- Hsairi Mohamed
- Hsiao Thomas
- Hsiao Thomas
- Hu Guoqing
- Hu Guoqing
- Huang John J.
- Huang John J.
- Huong Lan Thi Nguyen
- Huong Lan Thi Nguyen
- Huong Thanh Nguyen
- Huong Thanh Nguyen
- Hussen Mamusha Aman
- Hussen Mamusha Aman
- Huyen Phoc Do
- Huyen Phoc Do
- Huynh Chantal K.
- Huynh Chantal K.
- Iburg Kim Moesgaard
- Iburg Kim Moesgaard
- Ikeda Nayu
- Ikeda Nayu
- Ilesanmi Olayinka Stephen
- Ilesanmi Olayinka Stephen
- Iqbal Usman
- Iqbal Usman
- Irvani Seyed Sina Naghibi
- Irvani Seyed Sina Naghibi
- Irvine Caleb Mackay Salpeter
- Irvine Caleb Mackay Salpeter
- Islam Sheikh Mohammed Shariful
- Islam Sheikh Mohammed Shariful
- Islami Farhad
- Islami Farhad
- Jabbari Seyed Hossein Yahyazadeh
- Jabbari Seyed Hossein Yahyazadeh
- Jackson Maria D.
- Jackson Maria D.
- Jacobsen Kathryn H.
- Jacobsen Kathryn H.
- Jahangiry Leila
- Jahangiry Leila
- Jahanmehr Nader
- Jahanmehr Nader
- Jain Sudhir Kumar
- Jain Sudhir Kumar
- Jakovljevic Mihajlo
- Jakovljevic Mihajlo
- James Spencer L.
- James Spencer L.
- Jarlais Don C. Des
- Jarlais Don C. Des
- Jassal Simerjot K.
- Jassal Simerjot K.
- Jayatilleke Achala Upendra
- Jayatilleke Achala Upendra
- Jeemon Panniyammakal
- Jeemon Panniyammakal
- Jha Ravi Prakash
- Jha Ravi Prakash
- Jha Vivekanand
- Jha Vivekanand
- Ji John S.
- Ji John S.
- Jonas Jost B.
- Jonas Jost B.
- Jonnagaddala Jitendra
- Jonnagaddala Jitendra
- Jose Bruno Piassi Sao
- Jose Bruno Piassi Sao
- Joshi Ankur
- Joshi Ankur
- Jozwiak Jacek Jerzy
- Jozwiak Jacek Jerzy
- Jurisson Mikk
- Jurisson Mikk
- Kabir Zubair
- Kabir Zubair
- Kahsay Amaha
- Kahsay Amaha
- Kalani Rizwan
- Kalani Rizwan
- Kanchan Tanuj
- Kanchan Tanuj
- Kant Surya
- Kant Surya
- Kar Chittaranjan
- Kar Chittaranjan
- Karami Manoochehr
- Karami Manoochehr
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- Spinelli Angela
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- Sposato Luciano A.
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Srinivasan Vinay
- Stanaway Jeffrey D.
- Stanaway Jeffrey D.
- Starodubow Vladimir I.
- Starodubow Vladimir I.
- Steckling Nadine
- Steckling Nadine
- Stein Dan J.
- Stein Dan J.
- Stein Murray B.
- Stein Murray B.
- Stevanovic Goran
- Stevanovic Goran
- Stockfelt Leo
- Stockfelt Leo
- Stokes Mark A.
- Stokes Mark A.
- Sturua Lela
- Sturua Lela
- Subart Michelle L.
- Subart Michelle L.
- Sudaryanto Agus
- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Sufiyan Mu'awiyyah Babale
- Sulo Gerhard
- Sulo Gerhard
- Sunguya Bruno F.
- Sunguya Bruno F.
- Sur Patrick John
- Sur Patrick John
- Sykes Bryan I.
- Sykes Bryan I.
- Szoeke Cassandra E. I.
- Szoeke Cassandra E. I.
- Tabares-Seisdedos Rafael
- Tabares-Seisdedos Rafael
- Tabuchi Takahiro
- Tabuchi Takahiro
- Tadakamadla Santosh Kumar
- Tadakamadla Santosh Kumar
- Takahashi Ken
- Takahashi Ken
- Tandon Nikhil
- Tandon Nikhil
- Tassew Segen Gebremeskel
- Tassew Segen Gebremeskel
- Tavakkoli Mohammad
- Tavakkoli Mohammad
- Taveira Nuno
- Taveira Nuno
- Tehrani-Banihashemi Arash
- Tehrani-Banihashemi Arash
- Tekalign Tigist Gashaw
- Tekalign Tigist Gashaw
- Tekelemedhin Shishay Wandey
- Tekelemedhin Shishay Wandey
- Tekle Merhawi Gebremedhin
- Tekle Merhawi Gebremedhin
- Temesgen Habtamu
- Temesgen Habtamu
- Temsah Mohamad-Rani
- Temsah Mohamad-Rani
- Temsah Omar
- Temsah Omar
- Terkawi Abdullah Sulieman
- Terkawi Abdullah Sulieman
- Tessema Belay
- Tessema Belay
- Teweldemedhin Mebrahtu
- Teweldemedhin Mebrahtu
- Thankappan Kavumpurathu Raman
- Thankappan Kavumpurathu Raman
- Theis Andrew
- Theis Andrew
- Thirunavukkarasu Sathish
- Thirunavukkarasu Sathish
- Thomas Hannah J.
- Thomas Hannah J.
- Thomas Matthew Lloyd
- Thomas Matthew Lloyd
- Thomas Nihal
- Thomas Nihal
- Thou Maigeng
- Thou Maigeng
- Thurston George D.
- Thurston George D.
- Tilahun Binyam
- Tilahun Binyam
- Tillmana Taavi
- Tillmana Taavi
- To Quyen G.
- To Quyen G.
- Tobollik Myriarn
- Tobollik Myriarn
- Tonelli Marcello
- Tonelli Marcello
- Topor-Madry Roman
- Topor-Madry Roman
- Torre Anna E.
- Torre Anna E.
- Tortajada-Girbes Miguel
- Tortajada-Girbes Miguel
- Touvier Mathilde
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Tovani-Palone Marcos Roberto
- Towbin Jeffrey A.
- Towbin Jeffrey A.
- Tran Bach Xuan
- Tran Bach Xuan
- Tran Khanh Baca
- Tran Khanh Baca
- Truelsen Thomas Clement
- Truelsen Thomas Clement
- Tsadik Afewerki Gebremeskel
- Tsadik Afewerki Gebremeskel
- Tuzcu E. Murat
- Tuzcu E. Murat
- Tymeson Hayley D.
- Tymeson Hayley D.
- Tyrovolas Stefanos
- Tyrovolas Stefanos
- Ukwaja Kingsley N.
- Ukwaja Kingsley N.
- Ullah Irfan
- Ullah Irfan
- Updike Rachel L.
- Updike Rachel L.
- Usman Muhammad Shariq
- Usman Muhammad Shariq
- Uthman Olalekan A.
- Uthman Olalekan A.
- Vaduganathan Mutblab
- Vaduganathan Mutblab
- Vaezi Afsane
- Vaezi Afsane
- Valdez Pascual R.
- Valdez Pascual R.
- Van Donkelaar Aaron
- Van Donkelaar Aaron
- Varavikova Elena
- Varavikova Elena
- Varughese Santosh
- Varughese Santosh
- Vasankari Tommi Juhani
- Vasankari Tommi Juhani
- Vbsoughi Kia
- Vbsoughi Kia
- Venkateswaran Vidhya
- Venkateswaran Vidhya
- Venketasubramanian Narayanaswamy
- Venketasubramanian Narayanaswamy
- Villafaina Santos
- Villafaina Santos
- Violante Francesco S.
- Violante Francesco S.
- Vladimirov Sergey Konstantinovitch
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vlassov Vasily
- Vollset Stein Emil
- Vollset Stein Emil
- Vos Theo
- Vos Theo
- Vu Giang Thu
- Vu Giang Thu
- Vujcic Isidora S.
- Vujcic Isidora S.
- Wagnew Fasil Shiferaw
- Wagnew Fasil Shiferaw
- Waheed Yasir
- Waheed Yasir
- Waller Stephen G.
- Waller Stephen G.
- Walson Judd L.
- Walson Judd L.
- Wang Yafeng
- Wang Yafeng
- Wang Yanping
- Wang Yanping
- Wang Yuan-Pang
- Wang Yuan-Pang
- Weiderpass Elisabete
- Weiderpass Elisabete
- Weiknah Adhena Ayaliew
- Weiknah Adhena Ayaliew
- Weintraub Robert G.
- Weintraub Robert G.
- Weldegebreal Fitsum
- Weldegebreal Fitsum
- Werdecker Andrea
- Werdecker Andrea
- West J. Jason
- West J. Jason
- Westerman Ronny
- Westerman Ronny
- Whiteford Harvey A.
- Whiteford Harvey A.
- Widecka Justyna
- Widecka Justyna
- Wijeratne Tissa
- Wijeratne Tissa
- Winkler Andrea Sylvia
- Winkler Andrea Sylvia
- Wiyeh Alison B.
- Wiyeh Alison B.
- Wiysonge Charles Shey
- Wiysonge Charles Shey
- Wolfe Charles D. A.
- Wolfe Charles D. A.
- Wong Tien Yin
- Wong Tien Yin
- Wu Shoaling
- Wu Shoaling
- Xavier Denis
- Xavier Denis
- Xu Gelin
- Xu Gelin
- Yadgir Simon
- Yadgir Simon
- Yadollahpour Ali
- Yadollahpour Ali
- Yamada Tomohide
- Yamada Tomohide
- Yan Lijing L.
- Yan Lijing L.
- Yano Yuichiro
- Yano Yuichiro
- Yaseri Mehdi
- Yaseri Mehdi
- Yasin Jemal Yasin
- Yasin Jemal Yasin
- Yeshanely Alex
- Yeshanely Alex
- Yimer Ebrahim M.
- Yimer Ebrahim M.
- Yip Paul
- Yip Paul
- Yisma Engida
- Yisma Engida
- Yonemoto Naohiro
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yoon Seok-Jun
- Yotebieng Marcel
- Yotebieng Marcel
- Younis Mustafa Z.
- Younis Mustafa Z.
- Yousefifard Mahmoud
- Yousefifard Mahmoud
- Yu Chuanhua
- Yu Chuanhua
- Zaidi Zoubida
- Zaidi Zoubida
- Zamani Mohammad
- Zamani Mohammad
- Zavala-Arciniega Luis
- Zavala-Arciniega Luis
- Zhang Anthony Lin
- Zhang Anthony Lin
- Zhang Hao
- Zhang Hao
- Zhang Kai
- Zhang Kai
- Zimsen Stephanie M.
- Zimsen Stephanie M.
- Zodpey Sanjay
- Zodpey Sanjay
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk–outcome associations. With each annual GBD study, we update the GBD CRA to incorporate improved methods, new risks and risk–outcome pairs, and new data on risk exposure levels and risk–outcome associations.
Methods
We used the CRA framework developed for previous iterations of GBD to estimate levels and trends in exposure, attributable deaths, and attributable disability-adjusted life-years (DALYs), by age group, sex, year, and location for 84 behavioural, environmental and occupational, and metabolic risks or groups of risks from 1990 to 2017. This study included 476 risk–outcome pairs that met the GBD study criteria for convincing or probable evidence of causation. We extracted relative risk and exposure estimates from 46 749 randomised controlled trials, cohort studies, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. Using the counterfactual scenario of theoretical minimum risk exposure level (TMREL), we estimated the portion of deaths and DALYs that could be attributed to a given risk. We explored the relationship between development and risk exposure by modelling the relationship between the Socio-demographic Index (SDI) and risk-weighted exposure prevalence and estimated expected levels of exposure and risk-attributable burden by SDI. Finally, we explored temporal changes in risk-attributable DALYs by decomposing those changes into six main component drivers of change as follows: (1) population growth; (2) changes in population age structures; (3) changes in exposure to environmental and occupational risks; (4) changes in exposure to behavioural risks; (5) changes in exposure to metabolic risks; and (6) changes due to all other factors, approximated as the risk-deleted death and DALY rates, where the risk-deleted rate is the rate that would be observed had we reduced the exposure levels to the TMREL for all risk factors included in GBD 2017.
Findings
In 2017, 34·1 million (95% uncertainty interval [UI] 33·3–35·0) deaths and 1·21 billion (1·14–1·28) DALYs were attributable to GBD risk factors. Globally, 61·0% (59·6–62·4) of deaths and 48·3% (46·3–50·2) of DALYs were attributed to the GBD 2017 risk factors. When ranked by risk-attributable DALYs, high systolic blood pressure (SBP) was the leading risk factor, accounting for 10·4 million (9·39–11·5) deaths and 218 million (198–237) DALYs, followed by smoking (7·10 million [6·83–7·37] deaths and 182 million [173–193] DALYs), high fasting plasma glucose (6·53 million [5·23–8·23] deaths and 171 million [144–201] DALYs), high body-mass index (BMI; 4·72 million [2·99–6·70] deaths and 148 million [98·6–202] DALYs), and short gestation for birthweight (1·43 million [1·36–1·51] deaths and 139 million [131–147] DALYs). In total, risk-attributable DALYs declined by 4·9% (3·3–6·5) between 2007 and 2017. In the absence of demographic changes (ie, population growth and ageing), changes in risk exposure and risk-deleted DALYs would have led to a 23·5% decline in DALYs during that period. Conversely, in the absence of changes in risk exposure and risk-deleted DALYs, demographic changes would have led to an 18·6% increase in DALYs during that period. The ratios of observed risk exposure levels to exposure levels expected based on SDI (O/E ratios) increased globally for unsafe drinking water and household air pollution between 1990 and 2017. This result suggests that development is occurring more rapidly than are changes in the underlying risk structure in a population. Conversely, nearly universal declines in O/E ratios for smoking and alcohol use indicate that, for a given SDI, exposure to these risks is declining. In 2017, the leading Level 4 risk factor for age-standardised DALY rates was high SBP in four super-regions: central Europe, eastern Europe, and central Asia; north Africa and Middle East; south Asia; and southeast Asia, east Asia, and Oceania. The leading risk factor in the high-income super-region was smoking, in Latin America and Caribbean was high BMI, and in sub-Saharan Africa was unsafe sex. O/E ratios for unsafe sex in sub-Saharan Africa were notably high, and those for alcohol use in north Africa and the Middle East were notably low.
Interpretation
By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning
Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine
Erratum: \u3b22 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer (Cancer Cell (2018) 33(1) (75\u201390.e7), (S153561081730510X) (10.1016/j.ccell.2017.11.007))
- Author
- Casadei Riccardo
- Chen Xiaowei
- Chu Timothy
- Dantes Zahra
- Di Marco Mariacristina
- Friedman Richard A.
- Habenicht Andreas J.R.
- Hayakawa Yoku
- Ilmer Matthias
- Iuga Alina C.
- Jiang Zhengyu
- Kleespies Axel
- Macchini Marina
- Maurer H. Carlo
- Middelhoff Moritz
- Mohanta Sarajo K.
- Nagar Karan
- Neumann Jens
- Olive Kenneth P.
- Reichert Maximilian
- Remotti Helen
- Renz Bernhard W.
- Tailor Yagnesh
- Takahashi Ryota
- Tanaka Takayuki
- Valenti Giovanni
- Wang Timothy C.
- Werner Jens
- Westphalen C. Benedikt
- Worthley Daniel L.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
(Cancer Cell 33, 75\u201390.e1\u2013e7; January 8, 2018) In the originally published version of this article, the representative image of pancreatic H&E slides from LSL-Kras+/G12D;Pdx1-Cre (KC) mice at 20 weeks (Figure 1D) and the representative image of pancreatic H&E slides from cerulein-injected KC mice at 20 weeks on PLX-7486-containing diet (Cer PLX) (Figure 5E, right) were the same image. This happened because, during the first revision of our paper, we inadvertently labeled Figure 1D incorrectly and put the same image in both panels. We have gone back and reviewed pathology, and the images are consistent with what we described. We provide here a revised Figure 5, which includes a correct representative image of pancreatic H&E slides from cerulein-injected KC mice at 20 weeks on PLX-7486-containing diet in Figure 5E. We also identified two additional errors in Figures 3B and 3C. In the second bar from the right, respectively, Isoproterenol and Propanolol treatment was indicated, which is incorrect. These bars depict sphere number and sphere diameter of Propranolol only treated LSL-Kras+/G12D pancreatic spheres treated with an Adeno-Cre virus after 7 days in culture, respectively. Both Figure 3 and Figure 5 have now been corrected here and in the online version of the paper. The authors apologize for any confusion these errors may have caused. [Figure presented
\uce\ub22 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
- Author
- Casadei Riccardo
- Chen Xiaowei
- Chu Timothy
- Dantes Zahra
- Di Marco Mariacristina
- Friedman Richard A.
- Habenicht Andreas J. R.
- Hayakawa Yoku
- Ilmer Matthias
- Iuga Alina C.
- Jiang Zhengyu
- Kleespies Axel
- Macchini Marina
- Maurer H. Carlo
- Middelhoff Moritz
- Mohanta Sarajo K.
- Nagar Karan
- Neumann Jens
- Olive Kenneth P.
- Reichert Maximilian
- Remotti Helen
- Renz Bernhard W.
- Tailor Yagnesh
- Takahashi Ryota
- Tanaka Takayuki
- Valenti Giovanni
- Wang Timothy C.
- Werner Jens
- Westphalen C. Benedikt
- Worthley Daniel L.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Catecholamines stimulate epithelial proliferation, but the role of sympathetic nerve signaling in pancreatic ductal adenocarcinoma (PDAC) is poorly understood. Catecholamines promoted ADRB2-dependent PDAC development, nerve growth factor (NGF) secretion, and pancreatic nerve density. Pancreatic Ngf overexpression accelerated tumor development in LSL-Kras+/G12D;Pdx1-Cre (KC) mice. ADRB2 blockade together with gemcitabine reduced NGF expression and nerve density, and increased survival of LSL-Kras+/G12D;LSL-Trp53+/R172H;Pdx1-Cre (KPC) mice. Therapy with a Trk inhibitor together with gemcitabine also increased survival of KPC mice. Analysis of PDAC patient cohorts revealed a correlation between brain-derived neurotrophic factor (BDNF) expression, nerve density, and increased survival of patients on nonselective \uce\ub2-blockers. These findings suggest that catecholamines drive a feedforward loop, whereby upregulation of neurotrophins increases sympathetic innervation and local norepinephrine accumulation. Renz et al. show that catecholamines promote ADRB2-dependent pancreatic ductal adenocarcinoma development and secretion of neurotrophins (NT), which in turn promote tumor innervation leading to increased NE and tumor growth. Blockade of ADRB2 or NT receptors improves gemcitabine's therapeutic effect
β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer
- Author
- Alina C. Iuga
- Andreas J.R. Habenicht
- Axel Kleespies
- Bernhard W. Renz
- C. Benedikt Westphalen
- Daniel L. Worthley
- Giovanni Valenti
- H. Carlo Maurer
- Helen Remotti
- Jens Neumann
- Jens Werner
- Karan Nagar
- Kenneth P. Olive
- Mariacristina Di Marco
- Marina Macchini
- Matthias Ilmer
- Maximilian Reichert
- Moritz Middelhoff
- Riccardo Casadei
- Richard A. Friedman
- Ryota Takahashi
- Sarajo K. Mohanta
- Takayuki Tanaka
- Timothy C. Wang
- Timothy Chu
- Xiaowei Chen
- Yagnesh Tailor
- Yoku Hayakawa
- Zahra Dantes
- Zhengyu Jiang
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours
- Author
- Baba Taisuke
- Benmebarek Mohamed-Reda
- Blumenberg Viktoria
- Cadilha Bruno L.
- Dantes Zahra
- Dhoqina Dario
- Di Pilato Mauro
- Donnadieu Emmanuel
- Dorman Klara
- Duewell Peter
- Endres Stefan
- Gottschlich Adrian
- Grassmann Simon
- Grunmeier Ruth
- Halama Niels
- Hank Thomas
- Heise Constanze
- Hoerth Christine
- Hristov Michael
- Huynh Duc
- Janssen Klaus-Peter
- Jastroch Martin
- Joaquina Sandy
- Karches Clara H.
- Kobold Sebastian
- Konig Lars M.
- Kruger Stephan
- Kurzay Mathias
- Lamp Daniel
- Larimer Benjamin M.
- Lesch Stefanie
- Liss Andrew S.
- Lutz Johannes
- Marr Carsten
- Megens Remco T. A.
- Mempel Thorsten R.
- Metzger Philipp
- Nottebrock Alessia
- Oener Arman
- Ogonek Justyna
- Ormanns Steffen
- Pruessmann Jasper N.
- Rapp Moritz
- Rataj Felicitas
- Reichert Maximilian
- Reischer Anna
- Rothenfusser Simon
- Ruehland Svenja
- Schnurr Max
- Seifert Matthias
- Stoiber Stefan
- Subklewe Marion
- Tartour Eric
- Thomas Moritz
- Tokarew Nicholas
- Tran Thi
- Umut Oyku
- Vimeux Lene
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/06/2021
- Field of study
The efficacy of adoptive cell therapy for solid tumours is hampered by the poor accumulation of the transferred T cells in tumour tissue. Here, we show that the forced expression of the C-X-C chemokine receptor type 6 (CXCR6, whose ligand is highly expressed by human and murine pancreatic cancer cells and by tumour-infiltrating immune cells) in antigen-specific T cells enhanced the recognition and lysis of pancreatic cancer cells and the efficacy of adoptive cell therapy for pancreatic cancer. In mice with subcutaneous pancreatic tumours treated with T cells with either a transgenic T-cell receptor or a murine chimeric antigen receptor targeting the tumour-associated antigen epithelial cell-adhesion molecule, and in mice with orthotopic pancreatic tumours or patient-derived xenografts treated with T cells expressing a chimeric antigen receptor targeting mesothelin, the T cells exhibited enhanced intratumoral accumulation, exerted sustained antitumoral activity and prolonged animal survival only when co-expressing CXCR6. Arming tumour-specific T cells with tumour-specific chemokine receptors may represent a promising strategy for the realization of adoptive cell therapy for solid tumours
SUMO pathway inhibition targets an aggressive pancreatic cancer subtype
- Author
- Alexander Biederstädt
- Alexander Muckenhuber
- Andrea Coluccio
- Anna Scherger
- Aung
- Bailey
- Behan
- Bernier-Villamor
- Bhadury
- Bian
- Boj
- Christian Schneeweis
- Collisson
- Collisson
- Conradt
- Daemen
- Dieter Saur
- Eser
- Farrell
- Felix Orben
- Flaherty
- Flotho
- Gerrit Siegers
- Gillet
- Golan
- Günter Schneider
- H-P Lenhof
- Hassan
- He
- Hessmann
- Hoellein
- Iorio
- Johnson
- Jolanta Slawska
- Jonas Nilsson
- Jung
- Karasinska
- Kathrin Schunck
- Katja Steiger
- Kessler
- Kleeff
- Lara Schneider
- Lee
- Lisa Nilsson
- Lomberk
- Magen
- Markus Schick
- Martins
- Matthias Wirth
- Maximilian Reichert
- Moffitt
- Muckenhuber
- Mueller
- Mukhopadhyay
- Nicolle
- Noll
- Notta
- Pauli
- Rixe
- Roland Rad
- Seeler
- Siegel
- Stefan Müller
- Steve Langston
- Stöckel
- Tiriac
- Topham
- Toyoshima
- Ulrich Keller
- Van Cutsem
- Vlachogiannis
- Waddell
- Wilko Weichert
- Wirth
- Wirth
- Yang
- Yingfen Hong
- Zahra Dantes
- Zonera Hassan
- Publication venue
- 'BMJ'
- Publication date
- Field of study
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate Degu
- Abate Kalkidan Hassen
- Abay Solomon M.
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdela Jemal
- Abdelalim Ahmed
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Molla
- Abebe Zegeye
- Abil Olifan Zewdie
- Aboyans Victor
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen M. E.
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Ackerman Ilana N.
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adekanmbi Victor
- Ademi Zanfina
- Adetokunboh Olatunji O.
- Adib Mina G.
- Adsuar Jose C.
- Afanvi Kossivi Agbelenko
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Gina
- Agesa Kareha M.
- Aggarwal Rakesh
- Aghayan Sargis Aghasi
- Agrawal Anurag
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Sayem
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Akinyemiju Tomi
- Akseer Nadia
- Al-Eyadhy Ayman
- Al-Mekhlafi Hesham M.
- Al-Raddadi Rajaa M.
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Alashi Alaa
- Alavian Seyed Moayed
- Alene Kefyalew Addis
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla Francois
- Allebeck Peter
- Alonso Jordi
- Alsharif Ubai
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Aminde Leopold N.
- Amini Erfan
- Amiresmaili Mohammadreza
- Ammar Walid
- Amoako Yaw Ampem
- Anber Nahla Hamed
- Andrei Catalina Liliana
- Androudi Sofia
- Anh Quynh Nguyen
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Arabloo Jalal
- Aremu Olatunde
- Arnlov Johan
- Arora Amit
- Arora Megha
- Artaman Al
- Aryal Krishna K.
- Asayesh Hamid
- Ataro Zerihun
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F. G. A.
- Awasthi Ashish
- Ayer Rakesh
- Ayman Ziyad Al-Aly
- Azzopardi Peter S.
- Babazadeh Arefeh
- Bach Xuan Tran
- Badali Hamid
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Bamighausen Till Winfried
- Banach Maciej
- Banoub Joseph Adel Mattar
- Barac Aleksandra
- Barboza Miguel A.
- Barker-Collo Suzanne Lyn
- Barquera Simon
- Barrero Lope H.
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Behzadifar Meysam
- Bekele Bayu Begashaw
- Bekru Eyasu Tamru
- Belachew Abate Bekele
- Belay Yihalem Abebe
- Bell Michelle L.
- Bello Aminu K.
- Bennett Derrick A.
- Bensenor Isabela M.
- Berhane Adugnaw
- Bernabe Eduardo
- Bernstein Robert S.
- Beuran Mircea
- Beyranvand 'Find
- Bhala Neeraj
- Bhatt Samir
- Bhaumik Soumyadeep
- Bhutta Zulfiqar A.
- Biadgo Belete
- Bicer Burcu Kucuk
- Bidgoli Hassan Haghparast
- Biehl Molly H.
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bililign Nigus
- Bin Sayeed Muhammad Shahdaat
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- Lewycka Sonia
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- Liang Xiaofeng
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- Neamati Nahid
- Negoi Ionut
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- Shabaninejad Hosein
- Shafieesabet Azadeh
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- Shaikh Masood Ali
- Shams-Beyranvand Mehran
- Shamsi Mohammadbagher
- Sharafi Heidar
- Sharafi Kiomars
- Sharif Mehdi
- Sharif-Alhoseini Mahdi
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Sheikh Aziz
- Shi Peilin
- Shiadeh Malihe Nourollahpour
- Shibuya Kenji
- Shiferaw Mekonnen Sisay
- Shigematsu Mika
- Shiri Rahman
- Shirkoohi Reza
- Shiue Ivy
- Shokoohinia Yalda
- Shokraneh Farhad
- Shoman Haitham
- Shrime Mark G.
- Shushtari Zahra Jorjoran
- Si Si
- Siabani Soraya
- Sibai Abla Mehio
- Siddiqi Tariq J.
- Sigfusdottir Inga Dora
- Sigurvinsdottir Rannveig
- Silva Diego Augusto Santos
- Silva Joao Pedro
- Silveira Dayane Gabriele Alves
- Singam Narayana Sarma Venkata
- Singh Jasvinder A.
- Singh Narinder Pal
- Singh Virendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skirbekk Vegard
- Sliwa Karen
- Smith David L.
- Smith Mari
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- Sobhani Soheila
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- Soyiri Ireneous N.
- Sposato Luciano A.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Stanaway Jeffrey D.
- Starodubov Vladimir I.
- Stein Dan J.
- Steiner Caitlyn
- Steiner Timothy J.
- Stokes Mark A.
- Stovner Lars Jacob
- Subart Michelle L.
- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Sulo Gerhard
- Sunguya Bruno F.
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- Szoeke Cassandra E. I.
- Tabares-Seisdedos Rafael
- Tabuchi Takahiro
- Tadakamadla Santosh Kumar
- Tandon Nikhil
- Tassew Segen Gebremeskel
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R.
- Tehrani-Banihashemi Arash
- Teikelemedhin Shishay Wandey
- Tekalign Tigist Gashaw
- Tekle Merhawi Gebremedhin
- Temsah Mohamad-Hari
- Temsah Omar
- Terkawi Abdullah Sulieman
- Tessema Belay
- Teweldemedhin Mebrahtu
- Thankappan Kavumpurathu Raman
- Theis Andrew
- Thirunavukkarasu Sathish
- Thomas Nihal
- Tilahun Binyam
- To Quyen G.
- Tonelli Marcello
- Topor-Madry Roman
- Torre Anna E.
- Tortajada-Girbes Miguel
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Towbin Jeffrey A.
- Troeger Christopher E.
- Tsadik Afewerki Gebremeskel
- Tsoi Derrick
- Tyrovolas Stefanos
- Ukwaja Kingsley Nnanna
- Ullah Irfan
- Undurraga Eduardo A.
- Updike Rachel L.
- Usman Muhammad Shariq
- Uthman Olalekan A.
- Vaduganathan Muthiah
- Vaezi Afsane
- Valdez Pascual R.
- Van Itansingh C.
- Vanavikova Elena
- Varughese Santosh
- Vasankari Tommi Juhani
- Velasquez Ilais Moreno
- Venketasubramanian Narayanaswamy
- Villafaina Santos
- Violante Francesco S.
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vollset Stein Emil
- Vos Theo
- Vosoughi Kia
- Vujcic Isidora S.
- Wagnew Fasil Shiferaw
- Waheed Yasir
- Wang Yafeng
- Wang Yuan-Pang
- Weiderpass Elisabete
- Weintraub Robert G.
- Weiss Daniel J.
- Weldegebreal Fitsum
- Weldegwergs Kidu Gidey
- Werdecker Andrea
- West T. Eoin
- Westerman Ronny
- Whiteford Harvey A.
- Widecka Justyna
- Wijeratne Tissa
- Williams Hywel C.
- Wilner Lauren B.
- Wilson Shadrach
- Winkler Andrea Sylvia
- Wiyeh Alison B.
- Wiysonge Charles Shey
- Wolfe Charles D. A.
- Woolf Anthony D.
- Wyper Grant M. A.
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yamada Tomohide
- Yan Lijing L.
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Yeshaneh Alex
- Yimer Ebrahim M.
- Yip Paul
- Yisma Engida
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Yousefifard Mahmoud
- Yu Chuanhua
- Zadnik Vesna
- Zaidi Zoubida
- Zamani Mohammad
- Zandian Hamed
- Zar Heather J.
- Zenebe Zerihun Menlkalew
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zucker Inbar
- Zuhlke Liesl Joanna
- Publication venue
- Publication date
- 01/01/2018
- Field of study
Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate Degu
- Abate Kalkidan Hassen
- Abay Solomon M.
- Abbasi Nooshin
- Abbastabar Hedayat
- Abdel-Rahman Omar
- Abdela Jental
- Abdelalim Ahmed
- Abdi Alireza
- Abdoli Nasrin
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Haftom Temesgen
- Abebe Molla
- Abebe Zegeye
- Abebo Teshome Abuka
- Abejie Ayenew Negesse
- Aboyans Victor
- Abraha Haftom Niguse
- Abreu Daisy Maria Xavier
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen M. E.
- Accrombessi Manfred Mario Kolkou
- Acharya Pawan
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adetokunboh Olatunji O.
- Adhena Beyene Meressa
- Adhikari Tara Ballav
- Adib Mina C.
- Adou Arsene Kouablan
- Adsuar Jose C.
- Afarideh Mohsen
- Afique Suleman
- Afshin Ashkan
- Agarwal Gina
- Agesa Kareha M.
- Aghayan Sargis Aghasi
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmed Muktar Beshir
- Ahmed Sayem
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Akanda Ali S.
- Akbari Mohammad Esmaeil
- Akibu Mohammed
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Raddadi Rajaa M.
- Alahdab Fares
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- Wijeratne Tissa
- Winkler Andrea Sylvia
- Wiysonge Charles Shey
- Wolfe Charles D. A.
- Wu Shouling
- Wyper Grant M. A.
- Xu Gelin
- Yamada Tomohide
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Ye Pengpeng
- Yentur Gokalp Kadri
- Yeshaneh Alex
- Yimer Ebrahim M.
- Yip Paul
- Yisma Engida
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Yousefifard Mahmoud
- Yu Chuanhua
- Zadnik Vesna
- Zaidi Zoubida
- Zamani Mohammad
- Zare Zohreh
- Zeleke Mulugeta Mona
- Zenebe Zerihun Menlkalew
- Zerfu Taddese Alemu
- Zhang Xueying
- Zhao Xiu-Ju
- Zhou Maigeng
- Zhu Jun
- Zimsen Stephanie R. M.
- Zodpey Sanjay
- Zoeckler Leo
- Publication venue
- Publication date
- 01/01/2018
- Field of study