52 research outputs found

    Clay mineralogy and magnetic susceptibility of Oxisols in geomorphic surfaces

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    Studies analyzing the variability of clay minerals and magnetic susceptibility provide data for the delineation of site-specific management areas since many of their attributes are important to agronomy and the environment. This study aimed to evaluate the spatial variability of clay minerals, magnetic susceptibility, adsorbed phosphorus and physical attributes in Oxisols of sandstones in different geomorphic surfaces. For that purpose, soil samples were collected every 25 m along a transect located within the area where the geomorphic surfaces were identified and mapped. The transect occupied the central portion of 500 ha, where it was also sampled for density purposes with one sample per six hectares. Soil samples were collected at a depth of 0.0-0.2 m. The results of the physical, chemical, mineralogical and magnetic susceptibility analyses were subjected to statistical and geostatistical analyses. The nature of the clay minerals and magnetic susceptibility was dependent on the variation of the soil parent material. High values of magnetic susceptibility were associated with the presence of maghemite and magnetite of coarse size. The spatial variability of crystallinity and the content of Fe oxides, as well as magnetic susceptibility, were dependent on the age of the geomorphic surfaces. The youngest surface had greater spatial variability of these attributes. The iron (goethite and hematite) and aluminum (gibbsite) oxides in the youngest geomorphic surface influenced the low values of soil density and high values of total pore volume, micropores and P adsorption. The characterization of the spatial variability of Fe oxides and susceptibility allowed for the delineation of homogeneous areas

    Whole-genome sequencing reveals host factors underlying critical COVID-19

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    Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

    Land surface impacts on precipitation in the Netherlands

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    Dit proefschrift bestudeert de effecten van landgebruiksveranderingen uit het verleden en in de toekomst op neerslag in Nederland door middel van analyses van gemeten regendata en het gebruik van een weermodel

    Regent het meer in de Randstad?

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    Voor Amerikaanse steden is meermalen aangetoond dat er meer of intensievere neerslag “benedenwinds”(dus bij westenwind, ten oosten) van en in de stad valt. Ook voor Nederland wordt wel eens gespeculeerddat dit “stadseffect” bij zou dragen aan het maximum dat op de klimatologisch gemiddelde neerslagkaartente zien is nabij Rotterdam (www.klimaatatlas.nl). Op basis van dagelijkse stationsdata in de Randstad tonenwij aan dat dit inderdaad het geval is. Daarnaast blijkt uit uurlijkse radardata dat dit effect in zekere mateook ín steden optreedt

    Spatial precipitation patterns and trends in The Netherlands during 1951–2009

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    Significant increases in precipitation have been observed in The Netherlands over the last century. At the same time persistent spatial variations are apparent. The objective of this study is to analyse and explain these spatial patterns, focussing on changes in means and extremes for the period 1951–2009. To investigate different possibilities for the causes of spatial variations, a distinction was made between six regions based on mean precipitation, soil type and elevation, and four zones at different distances to the coast. Spatial maxima in mean precipitation inland and over elevated areas are mainly formed in winter and spring, while maxima along the coast are generated in autumn. Daily precipitation maxima are found in the central West coast and over elevated areas. Upward trends in daily precipitation are highest from February to April and lowest from July to September. The strongest and most significant increases are found along the coast. For several seasonal and climatological periods diverging behaviour between coastal and inland zones is observed. We find that distance to the coast gives a more consistent picture for the seasonal precipitation changes than a classification based on surface characteristics. Therefore, from the investigated surface factors, we consider sea surface temperature to have the largest influence on precipitation in The Netherlands

    Observed urban effects on precipitation along the Dutch West coast

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    Expansion of urban areas has profound effects on land surface characteristics. As such, the land surface can exert influence on atmospheric parameters that might alter precipitation amounts or patterns. In this study, precipitation observations near urban areas along the West coast of the Netherlands are investigated throughout the 1951–2010 period. An innovative analysis methodology is used to deal with the small and fragmented urban areas in the Netherlands. The results show that daily precipitation totals downwind of urban areas are, on average, about 7% higher than precipitation in the rest of the Dutch West coast. Precipitation enhancements up to 20% are found depending on wind direction and time period. These results are comparable with studies from around the globe and show that the influence of relatively small fragmented urban areas, as are present in the Netherlands, can be similar to the influence of large metropolitan areas on precipitation
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