Parada cardíaca extra-hospitalar: fatores determinantes da sobrevida imediata após manobras de ressuscitação cardiopulmonar

OBJECTIVE: to analyze determinant factors for the immediate survival of persons who receive cardiopulmonary resuscitation from the advanced support units of the Mobile Emergency Medical Services (SAMU) of Belo Horizonte. METHOD: this is a retrospective, epidemiological study which analyzed 1,165 assistance forms, from the period 2008 - 2010. The collected data followed the Utstein style, being submitted to descriptive and analytical statistics with tests with levels of significance of 5%. RESULTS: the majority were male, the median age was 64 years, and the ambulance response time, nine minutes. Immediate survival was observed in 239 persons. An association was ascertained of this outcome with "cardiac arrest witnessed by persons trained in basic life support" (OR=3.49; pOBJETIVO: analizar factores determinantes de la sobrevida inmediata de personas que recibieron maniobras de resucitación cardiopulmonar por los equipos de soporte avanzado del Servicio de Atención Móvil de Urgencia de Belo Horizonte. MÉTODO: se trata de estudio epidemiológico, retrospectivo en el cual fueron analizadas 1.165 fichas de atención, en el período de 2008 a 2010. Los datos recolectados siguieron el estilo Utstein, siendo sometidos a la estadística descriptiva y analítica con pruebas de nivel de significancia de 5%. RESULTADOS: la mayoría era del sexo masculino, la mediana de la edad fue de 64 años y el de tiempo de traslado, nueve minutos. La sobrevida inmediata fue observada en 239 personas. Se verificó asociación de ese resultado con la "parada cardiorrespiratoria presenciada por personas entrenadas en soporte básico de vida" (OR=3,49; pOBJETIVO: analisar fatores determinantes da sobrevida imediata de pessoas que receberam manobras de ressuscitação cardiopulmonar pelas equipes de suporte avançado do Serviço de Atendimento Móvel de Urgência, de Belo Horizonte. MÉTODO: trata-se de estudo epidemiológico, retrospectivo, no qual foram analisadas 1.165 fichas de atendimento, do período de 2008 a 2010. Os dados coletados seguiram o estilo Utstein, sendo submetidos à estatística descritiva e analítica com testes de nível de significância de 5%. RESULTADOS: a maioria era do sexo masculino, a mediana da idade foi de 64 anos e a do tempo de deslocamento, nove minutos. A sobrevida imediata foi observada em 239 pessoas. Verificou-se associação desse desfecho com a "parada cardiorrespiratória presenciada por pessoas treinadas em suporte básico de vida" (OR=3,49;

EFFECT OF SIMVASTATIN ON THE GROWTH INHIBITION OF Candida albicans

Yeasts of the Candida genus often interact in a commensal colo-niser of humans. However, in certain conditions they can cause infections such as superficial or systemic candidiasis, which are responsible for high mortality rates because of ineffective diagno-ses and treatments. The mechanisms associated with the virulence of Candida albicans must be understood since they have acquired growing importance due to their increased resistance to drugs such as Fluconazole and Amphotericin B, both commonly used in therapeutic hospital routines. The present study evaluated the sen-sibility of isolated C. albicans to simvastatin, which acts on the ergosterol of the plasma membrane of this fungus. The sensitivity profile of the isolated C. albicans ATCC 90028 to simvastatin was determined by the agar diffusion methodology. The concen-tration of simvastatin used ranged from 78 to 2500μg.mL-1. The results obtained demonstrated that simvastatin has great potential for being used against C. albicans

EFFECT OF SIMVASTATIN ON THE GROWTH INHIBITION OF Candida albicans

Yeasts of the Candida genus often interact in a commensal colo-niser of humans. However, in certain conditions they can cause infections such as superficial or systemic candidiasis, which are responsible for high mortality rates because of ineffective diagno-ses and treatments. The mechanisms associated with the virulence of Candida albicans must be understood since they have acquired growing importance due to their increased resistance to drugs such as Fluconazole and Amphotericin B, both commonly used in therapeutic hospital routines. The present study evaluated the sen-sibility of isolated C. albicans to simvastatin, which acts on the ergosterol of the plasma membrane of this fungus. The sensitivity profile of the isolated C. albicans ATCC 90028 to simvastatin was determined by the agar diffusion methodology. The concen-tration of simvastatin used ranged from 78 to 2500μg.mL-1. The results obtained demonstrated that simvastatin has great potential for being used against C. albicans

Ocorrências de acidentes de trânsito atendidas pelo serviço de atendimento móvel de urgência em Belo Horizonte

O Servio de Atendimento Mvel de Urgncia de Belo Horizonte (SAMU/BH), implantado em 2003, conta com uma equipe de profissionais para atender as diversas situaes de urgncia/ emergncia, dentre esses atendimentos os acidentes de trnsito. Este estudo foi desenvolvido com o objetivo de descrever as ocorrncias de acidentes de trnsito atendidas pelo SAMU/BH/Minas Gerais, no ano de 2009. Para a coleta de dados foi realizado um estudo epidemiolgico, observacional de delineamento transversal sobre as ocorrncias destes acidentes atendidos pelas unidades de suporte avanado (USA). A pesquisa foi feita mediante a avaliao de 1295 fichas de atendimento pr-hospitalar (FAPH), nas quais houve relato de acidente de trnsito em 2009. O principal veculo envolvido foi motocicleta (319-24,7%) em seguida, os automveis (306-23,7%). A maioria dos atendimentos ocorreu no perodo noturno, a maior frequncia nos fins de semana: sbado (223) e domingo (214), com uma mdia de 70 atendimentos/ms. O maior percentual (902-69,7%) foi do sexo masculino, idade variando de 0 a 94 anos com destaque para a faixa etria mdia adulto jovem (20 a 39 anos). O tempo mdio da chegada ao local foi de 10 minutos. Das 1295 ocorrncias, 150 (11,6%) vtimas foram a bito, sendo esta chegada da ambulncia, durante o atendimento no local do acidente, durante o deslocamento ou durante a admisso no hospital. Pde-se perceber que um nmero elevado de vtimas (1030- 79,6%) manteve sobrevida. Os resultados comprovaram a eficincia de toda a equipe do SAMU e mostrou a importncia do seu papel exercido na sociedade

Functional capacity assessment in aged diabetic patients

Diabetes mellitus (DM) is associated with much comorbidity which compromise even more the aged functional capacity. This chronic illness is associated with the risk of disability to perform activities of daily living. The purpose of this study was to compare the functional capacity of diabetic and non-diabetic aged. It is a cross sectional study, that evaluated forty aged, dived in 2 groups, 20 diabetic (71.1±4.6 years) and 20 non-diabetic (71.7±4.4 years). The groups where similar in gender, age and BMI. To assess functional capacity, the Physical Performance Test Modified (PPTM) and the six minute walk test were performed. The rate of perceived exertion was examined through the Borg scale and the sensibility test through the perception of a group of six nylon Semmes-Weinstein monofilaments. Data were analyzed through Mann-Whitney test. The group of diabetic aged walked a shorter distance in the 6 minute walk test (396±55.6x481.5±73.1 m; p=0.0003) and showed worst sensibility test when compared to the non-diabetic elderly, but no difference was found in the PPTM. The diabetic elderly showed inferior physical ability compared to the non-diabetic elderly.O diabetes mellitus (DM) tem associação com várias comorbidades que comprometem ainda mais a funcionalidade do idoso. Essa doença crônica está vinculada ao risco de incapacidade para realizar atividades rotineiras. O objetivo deste estudo foi comparar a capacidade funcional de idosos diabéticos e não diabéticos. Trata-se de uma pesquisa observacional transversal que avaliou 40 idosos, divididos em dois grupos, sendo 20 diabéticos (71,1±4,6 anos) e 20 não diabéticos (71,7±4,4 anos). Os grupos foram semelhantes quanto ao gênero, idade e índice de massa corpórea (IMC). Para avaliação da capacidade funcional foram realizados o teste de desempenho físico modificado (TDMF) e o teste de caminhada de seis minutos (TC6). A percepção subjetiva do esforço foi avaliada por meio da escala de Borg modificada e o teste de sensibilidade pela percepção de um conjunto de seis monofilamentos de náilon de Semmes-Weinstein. Os dados foram analisados por meio do Mann-Whitney test. O grupo de idosos diabéticos percorreu menor distância no TC6 (396±55,6x481,5±73,1 m; p=0,0003) e apresentou pior teste de sensibilidade quando comparado com os não diabéticos, mas nenhuma diferença foi encontrada no TDMF. Os idosos diabéticos relataram pior aptidão física quando comparados com os não diabéticos

Spinnability and characteristics of polyvinylidene fluoride (PVDF)-based bicomponent fibers with a carbon nanotube (CNT) modified polypropylene core for piezoelectric applications

Biodiesel production has received considerable attention in the recent past as a nonpolluting fuel. However, this assertion has been based on its biodegradability and reduction in exhaust emissions. Assessments of water and soil biodiesel pollution are still limited. Spill simulation with biodiesel and their diesel blends in soils were carried out, aiming at analyzing their cytotoxic and genotoxic potentials. While the cytotoxicity observed may be related to diesel contaminants, the genotoxic and mutagenic effects can be ascribed to biodiesel pollutants. Thus, taking into account that our data stressed harmful effects on organisms exposed to biodiesel-polluted soils, the designation of this biofuel as an environmental-friendly fuel should be carefully reviewed to assure environmental quality. (C) 2011 Elsevier B.V. All rights reserved

Perfil de mulheres atendidas em hospital de alta complexidade devido a agressão por queimadura pelo parceiro

Objective: To describe the epidemiological profile of women who suffered assault due to burns by their intimate partner and were treated at a referral hospital for trauma emergencies in the State of Minas Gerais, Brazil. Method: This cross-sectional study analyzed the medical records of 19 women who were victims of assault due to burns by their intimate partner from 2016 to 2019in a referral hospital for trauma emergencies in Minas Gerais. Results: Most victims were Brown, married, with children, worked informally, and were assaulted at home. Care included very urgent/orange priority treatment, severe second-degree burns, hospitalization, surgical procedures, complications, and post-discharge outpatient follow-up. Conclusion: Health services must establish mechanisms to track and investigate violence against women, preventing the worsening of their condition and offering adequate support. Professionals must be prepared at all levels of care and use surveillance and promotion strategies.Objetivos: Describir el perfil epidemiológico de mujeres que sufrieron agresión por quemaduras por parte de su pareja íntima, atendidas en un hospital de referencia para trauma, urgencia y emergencia en el Estado de Minas Gerais. Método: Estudio transversal que analizó las historias clínicas de víctimas de agresión por quemaduras corporales por parte de un compañero íntimo de 2016 a 2019. Los datos fueron sometidos a análisis estadístico descriptivo. Resultados: La mediana de edad de las 19 mujeres maltratadas fue de 38 años. La mayoría eran morenas (68,42%), casadas (52,63%), con hijos (73,68%), tenían trabajo informal (47,37%) y sufrían agresiones en el hogar (73,68%). En cuanto a la atención, el nivel de prioridad más frecuente fue muy urgente/naranja (61,54 %), quemadura muy grave de segundo grado (89,47 %), necesidad de hospitalización (94,74 %), procedimiento quirúrgico (78,95 %), con complicaciones (57,89 %). %) y seguimiento ambulatorio posterior al alta (73,68%). Conclusión: Las víctimas fueron graves y demandaron atención especializada y de alta complejidad, con repercusiones posteriores a la quemadura para las mujeres agredidas.Objetivo: Descrever o perfil dos atendimentos a mulheres que foram agredidas pelo parceiro íntimo e sofreram queimaduras em hospital de referência em trauma, urgência e emergência do Estado de Minas Gerais. Método: estudo transversal, que analisou prontuários de 19 mulheres vítimas de agressão por queimadura realizadas pelo parceiro íntimo em um hospital de referência em trauma, urgência e emergência no período de 2016 a 2019. Resultados: A maioria das vítimas era parda, casada, com filhos, trabalhava informalmente e foi agredida na residência. O atendimento incluiu prioridade muito urgente/laranja, queimaduras graves de 2º grau, internação, procedimentos cirúrgicos, complicações e acompanhamento ambulatorial pós-alta. Conclusão: Os resultados indicam atendimentos de alta complexidade, o que implica necessidade de os serviços de saúde estabelecerem mecanismos de rastreamento e investigação da violência contra a mulher, bem como preparo da equipe, prevenindo agravamentos e oferecendo suporte adequado

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio