118 research outputs found

    Apparent multiple Delta m^2_32 in muon anti-neutrino and muon neutrino survival oscillations from non-standard interaction matter effect

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    Neutrinos propagating through matter may participate in forward coherent neutral-current-like scattering arising from non-standard interactions as well as from the Mikheyev-Smirnov-Wolfenstein matter potential VeV_e. We show that at fixed long baselines through matter of constant density, the non-standard interaction potential ϵμτVe\epsilon_{\mu\tau} V_e can contribute an additional term to the oscillation phase whose sign differs for \anumu versus \numu propagation in matter. Its presence can cause different apparent Δm2\Delta m^2 to be erroneously inferred on the basis of oscillations in vacuum, with values lying above (for \anumu) or below (for \numu) the actual Δm322\Delta m^2_{32} for the case where ϵμτ\epsilon_{\mu\tau} is predominantly real-valued and of sign opposite to Δm322\Delta m_{32}^2. An NSI scenario invoking only (ϵμτ)\Re(\epsilon_{\mu\tau}) is shown to be capable of accounting for a disparity recently reported between oscillation survival for \anumu and \numu fluxes measured at 735 km735~\mathrm{km} by the MINOS experiment. Implications for mantle traversal by atmospheric neutrinos are examined. The NSI matter potential with non-maximal mixing could evade conventional atmospheric neutrino analyses which do not distinguish \numu from \anumu on an event-by-event basis.Comment: 7 pages, 5 figures. Accepted for publication in Physical Review

    Federated Learning for Predictive Maintenance and Quality Inspection in Industrial Applications

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    Data-driven machine learning is playing a crucial role in the advancements of Industry 4.0, specifically in enhancing predictive maintenance and quality inspection. Federated learning (FL) enables multiple participants to develop a machine learning model without compromising the privacy and confidentiality of their data. In this paper, we evaluate the performance of different FL aggregation methods and compare them to central and local training approaches. Our study is based on four datasets with varying data distributions. The results indicate that the performance of FL is highly dependent on the data and its distribution among clients. In some scenarios, FL can be an effective alternative to traditional central or local training methods. Additionally, we introduce a new federated learning dataset from a real-world quality inspection setting

    The Natural Cytotoxicity Receptor 1 Contribution to Early Clearance of Streptococcus pneumoniae and to Natural Killer-Macrophage Cross Talk

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    Natural killer (NK) cells serve as a crucial first line of defense against tumors, viral and bacterial infections. We studied the involvement of a principal activating natural killer cell receptor, natural cytotoxicity receptor 1 (NCR1), in the innate immune response to S. pneumoniae infection. Our results demonstrate that the presence of the NCR1 receptor is imperative for the early clearance of S. pneumoniae. We tied the ends in vivo by showing that deficiency in NCR1 resulted in reduced lung NK cell activation and lung IFNγ production at the early stages of S. pneumoniae infection. NCR1 did not mediate direct recognition of S. pneumoniae. Therefore, we studied the involvement of lung macrophages and dendritic cells (DC) as the mediators of NK-expressed NCR1 involvement in response to S. pneumoniae. In vitro, wild type BM-derived macrophages and DC expressed ligands to NCR1 and co-incubation of S. pneumoniae-infected macrophages/DC with NCR1-deficient NK cells resulted in significantly lesser IFNγ levels compared to NCR1-expressing NK cells. In vivo, ablation of lung macrophages and DC was detrimental to the early clearance of S. pneumoniae. NCR1-expressing mice had more potent alveolar macrophages as compared to NCR1-deficient mice. This result correlated with the higher fraction of NCR1-ligandhigh lung macrophages, in NCR1-expressing mice, that had better phagocytic activity compared to NCR1-liganddull macrophages. Overall, our results point to the essential contribution of NK-expressed NCR1 in early response to S. pneumoniae infection and to NCR1-mediated interaction of NK and S. pneumoniae infected-macrophages and -DC

    LSST Science Book, Version 2.0

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    A survey that can cover the sky in optical bands over wide fields to faint magnitudes with a fast cadence will enable many of the exciting science opportunities of the next decade. The Large Synoptic Survey Telescope (LSST) will have an effective aperture of 6.7 meters and an imaging camera with field of view of 9.6 deg^2, and will be devoted to a ten-year imaging survey over 20,000 deg^2 south of +15 deg. Each pointing will be imaged 2000 times with fifteen second exposures in six broad bands from 0.35 to 1.1 microns, to a total point-source depth of r~27.5. The LSST Science Book describes the basic parameters of the LSST hardware, software, and observing plans. The book discusses educational and outreach opportunities, then goes on to describe a broad range of science that LSST will revolutionize: mapping the inner and outer Solar System, stellar populations in the Milky Way and nearby galaxies, the structure of the Milky Way disk and halo and other objects in the Local Volume, transient and variable objects both at low and high redshift, and the properties of normal and active galaxies at low and high redshift. It then turns to far-field cosmological topics, exploring properties of supernovae to z~1, strong and weak lensing, the large-scale distribution of galaxies and baryon oscillations, and how these different probes may be combined to constrain cosmological models and the physics of dark energy.Comment: 596 pages. Also available at full resolution at http://www.lsst.org/lsst/sciboo

    DNA Hybridization Sensors Based on Electrochemical Impedance Spectroscopy as a Detection Tool

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    Recent advances in label free DNA hybridization sensors employing electrochemical impedance spectroscopy ( EIS) as a detection tool are reviewed. These sensors are based on the modulation of the blocking ability of an electrode modified with a probe DNA by an analyte, i.e., target DNA. The probe DNA is immobilized on a self-assembled monolayer, a conducting polymer film, or a layer of nanostructures on the electrode such that desired probe DNA would selectively hybridize with target DNA. The rate of charge transfer from the electrode thus modified to a redox indicator, e. g., [Fe(CN)(6)](3-/4-), which is measured by EIS in the form of charge transfer resistance (R(ct)), is modulated by whether or not, as well as how much, the intended target DNA is selectively hybridized. Efforts made to enhance the selectivity as well as the sensitivity of DNA sensors and to reduce the EIS measurement time are briefly described along with brief future perspectives in developing DNA sensors.open484
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