3,113 research outputs found
Modeling SN 1996cr's X-ray lines at high-resolution: Sleuthing the ejecta/CSM geometry
SN 1996cr, located in the Circinus Galaxy (3.7 Mpc, z ~ 0.001) was
non-detected in X-rays at ~ 1000 days yet brightened to ~ 4 x 10^{39} erg/s
(0.5-8 keV) after 10 years (Bauer et al. 2008). A 1-D hydrodynamic model of the
ejecta-CSM interaction produces good agreement with the measured X-ray light
curves and spectra at multiple epochs. We conclude that the progenitor of SN
1996cr could have been a massive star, M > 30 M_solar, which went from an RSG
to a brief W-R phase before exploding within its ~ 0.04 pc wind-blown shell
(Dwarkadas et al. 2010). Further analysis of the deep Chandra HETG observations
allows line-shape fitting of a handful of bright Si and Fe lines in the
spectrum. The line shapes are well fit by axisymmetric emission models with an
axis orientation ~ 55 degrees to our line-of-sight. In the deep 2009 epoch the
higher ionization Fe XXVI emission is constrained to high lattitudes: the
Occam-est way to get the Fe H-like emission coming from high latitude/polar
regions is to have more CSM at/around the poles than at mid and lower
lattitudes, along with a symmetric ejecta explosion/distribution. Similar
CSM/ejecta characterization may be possible for other SNe and, with
higher-throughput X-ray observations, for gamma-ray burst remnants as well.Comment: 4 pages, 5 figures. To appear in the Proceedings of the Gamma Ray
Bursts 2010 Conference, Annapolis, USA. Editors: McEnery, Racusin, Gehrel
Universal angular magnetoresistance and spin torque in ferromagnetic/normal metal hybrids
The electrical resistance of ferromagnetic/normal-metal (F/N)
heterostructures depends on the nature of the junctions which may be tunnel
barriers, point contacts, or intermetallic interfaces. For all junction types,
the resistance of disordered F/N/F perpendicular spin valves as a function of
the angle between magnetization vectors is shown to obey a simple universal
law. The spin-current induced magnetization torque can be measured by the
angular magnetoresistance of these spin valves. The results are generalized to
arbitrary magnetoelectronic circuits
From Digital to Analogue Magnetoelectronics: Theory of Transport in Non-Collinear Magnetic Nanostructures
Magnetoelectronics is mainly digital, i.e. governed by up and down
magnetizations. In contrast, analogue magnetoelectronics makes use of phenomena
occuring for non-collinear magnetization configurations. Here we review
theories which have recently been applied to the transport in non-collinear
magnetic nanostructures in two and multiterminal structures, viz. random matrix
and circuit theory. Both are not valid for highly transparent systems in a
resistive environment like perpendicular metallic spin valves. The solution to
this problem is a renormalization of the conventional and spin-mixing
conductance parameters.Comment: To be published in "Advance in Solid State Physics", edited by B.
Kramer, Springer Verlag, Berlin, 200
Semiclassical Concepts in Magnetoelectronics
Semiclassical theories of electron and spin transport in metallic magnetic
structures are reviewed with emphasis on the role of disorder and electronic
band structures in the current perpendicular to the interface plane (CPP)
transport configuration.Comment: Proceedings of the NEC Symposium on "Spin-related Quantum Transport
in Mesoscopic Systems", to be published in the Journal of Materials Science
and Engineering
Theory of a Magnetically-Controlled Quantum-Dot Spin Transistor
We examine transport through a quantum dot coupled to three ferromagnetic
leads in the regime of weak tunnel coupling. A finite source-drain voltage
generates a nonequilibrium spin on the otherwise non-magnetic quantum dot. This
spin accumulation leads to magnetoresistance. A ferromagnetic but current-free
base electrode influences the quantum-dot spin via incoherent spin-flip
processes and coherent spin precession. As the dot spin determines the
conductance of the device, this allows for a purely magnetic transistor-like
operation. We analyze the effect of both types of processes on the electric
current in different geometries.Comment: 7 pages, 6 figure
A Geometrically Supported Candidate Multiply-Imaged by the Hubble Frontier Fields Cluster Abell 2744
The deflection angles of lensed sources increase with their distance behind a
given lens. We utilize this geometric effect to corroborate the
photometric redshift estimate of a faint near-IR dropout,
triply-imaged by the massive galaxy cluster Abell 2744 in deep Hubble Frontier
Fields images. The multiple images of this source follow the same symmetry as
other nearby sets of multiple images which bracket the critical curves and have
well defined redshifts (up to ), but with larger deflection
angles, indicating that this source must lie at a higher redshift. Similarly,
our different parametric and non-parametric lens models all require this object
be at , with at least 95\% confidence, thoroughly excluding the
possibility of lower-redshift interlopers. To study the properties of this
source we correct the two brighter images for their magnifications, leading to
a SFR of /yr, a stellar mass of , and an age of Myr (95\% confidence). The intrinsic
apparent magnitude is 29.9 AB (F160W), and the rest-frame UV ()
absolute magnitude is . This corresponds to (, adopting ), making
this candidate one of the least luminous galaxies discovered at .Comment: 7 pages, 4 figures, 1 table; V2: very minor changes, ApJ Letters
Accepte
Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer.
BackgroundUnderstanding cell signaling pathways that contribute to metastatic colon cancer is critical to risk stratification in the era of personalized therapeutics. Here, we dissect the unique involvement of mitogenic pathways in a TGFβ or activin-induced metastatic phenotype of colon cancer.MethodMitogenic signaling/growth factor receptor status and p21 localization were correlated in primary colon cancers and intestinal tumors from either AOM/DSS treated ACVR2A (activin receptor 2) -/- or wild type mice. Colon cancer cell lines (+/- SMAD4) were interrogated for ligand-induced PI3K and MEK/ERK pathway activation and downstream protein/phospho-isoform expression/association after knockdown and pharmacologic inhibition of pathway members. EMT was assessed using epithelial/mesenchymal markers and migration assays.ResultsIn primary colon cancers, loss of nuclear p21 correlated with upstream activation of activin/PI3K while nuclear p21 expression was associated with TGFβ/MEK/ERK pathway activation. Activin, but not TGFβ, led to PI3K activation via interaction of ACVR1B and p85 independent of SMAD4, resulting in p21 downregulation. In contrast, TGFβ increased p21 via MEK/ERK pathway through a SMAD4-dependent mechanism. While activin induced EMT via PI3K, TGFβ induced EMT via MEK/ERK activation. In vivo, loss of ACVR2A resulted in loss of pAkt, consistent with activin-dependent PI3K signaling.ConclusionAlthough activin and TGFβ share growth suppressive SMAD signaling in colon cancer, they diverge in their SMAD4-independent pro-migratory signaling utilizing distinct mitogenic signaling pathways that affect EMT. p21 localization in colon cancer may determine a dominant activin versus TGFβ ligand signaling phenotype warranting further validation as a therapeutic biomarker prior to targeting TGFβ family receptors
Spatial Geometry of the Electric Field Representation of Non-Abelian Gauge Theories
A unitary transformation \Ps [E]=\exp (i\O [E]/g) F[E] is used to simplify
the Gauss law constraint of non-abelian gauge theories in the electric field
representation. This leads to an unexpected geometrization because
\o^a_i\equiv -\d\O [E]/\d E^{ai} transforms as a (composite) connection. The
geometric information in \o^a_i is transferred to a gauge invariant spatial
connection \G^i_{jk} and torsion by a suitable choice of basis vectors for
the adjoint representation which are constructed from the electric field
. A metric is also constructed from . For gauge group ,
the spatial geometry is the standard Riemannian geometry of a 3-manifold, and
for it is a metric preserving geometry with both conventional and
unconventional torsion. The transformed Hamiltonian is local. For a broad class
of physical states, it can be expressed entirely in terms of spatial geometric,
gauge invariant variables.Comment: 16pp., REVTeX, CERN-TH.7238/94 (Some revision on Secs.3 and 5; one
reference added
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