Analysis of Food Insecurity and Coping Mechanisms among Rural Women in Boripe Local Government Area of Osun State, Nigeria

The study was based on food insecurity level and coping mechanisms among the rural women in Boripe local government area, of Osun state. The study therefore examined the level of food insecurity and coping mechanisms among the rural women. The broad objective of the study was to determine the level of food insecurity and coping strategies among the different respondents in Boripe Local government area of Osun state. The study utilized multi stage sampling technique which involved more than one sample stage and systematic random sampling technique to get the required sample for the study, which gives room for 120 well-structured questionnaires. The data were analyzed using descriptive statistics, food insecurity coping strategy and household food insecurity scale (HFIAS) and Logit regression model. The findings revealed that most of the respondents were in their active age and most were not. Al respondents were females with 72.5% married. Few  (30%) of the respondents never worry about their households food security, 46.7% sometimes had to eat a limited variety of food 30.0% rarely ate a limited variety of food and only 16.7% could eat the variety of food they wanted based on the insecurity condition where house members had to eat some food that they didn’t really want to eat 20%, had nothing to worry about, 39.2% rarely did 32.5% sometimes had to and only 8.3% often had to worry about this insecurity condition. 37.5% of the respondent always had food to eat, 41.7% rarely ran out of food14.2% sometimes ran out of food and only6.7% of the total respondent often had no food to eat of any kind in their household. 37.5% of the respondent never went to bed hungry, Furthermore, the result indicated that 70% of the respondents were food insecure while only 30% were food secure

Missed, not missing: Phylogenomic evidence for the existence of Avian FoxP3

The Forkhead box transcription factor FoxP3 is pivotal to the development and function of regulatory T cells (Tregs), which make a major contribution to peripheral tolerance. FoxP3 is believed to perform a regulatory role in all the vertebrate species in which it has been detected. The prevailing view is that FoxP3 is absent in birds and that avian Tregs rely on alternative developmental and suppressive pathways. Prompted by the automated annotation of foxp3 in the ground tit (Parus humilis) genome, we have questioned this assumption. Our analysis of all available avian genomes has revealed that the foxp3 locus is missing, incomplete or of poor quality in the relevant genomic assemblies for nearly all avian species. Nevertheless, in two species, the peregrine falcon (Falco peregrinus) and the saker falcon (F. cherrug), there is compelling evidence for the existence of exons showing synteny with foxp3 in the ground tit. A broader phylogenomic analysis has shown that FoxP3 sequences from these three species are similar to crocodilian sequences, the closest living relatives of birds. In both birds and crocodilians, we have also identified a highly proline-enriched region at the N terminus of FoxP3, a region previously identified only in mammals

The Impact of Grant Administration and Strategic Management in Nonprofit Organizations

Mission statement alone and getting grants do not solve the problem of nonprofit organizations. Some nonprofit organizations are running into problems due to problems with ethics, lack of professional grant administrators and misuse of grants. These affect developments, completion of programs, hiring of more staffs and lack of access to services. This study explores the impact of grant administration and strategic management in nonprofit organizations. Using mixed-methods that were analyzed through cross tabulations, frequency tables, graphs and correlation analysis, there is evidence of correlation between the numbers of programs completed and the impacts of grant administration. The findings suggest that nonprofit organizations will do better with more grants for program development and not for the introduction of strategic management

Phenotypic and functional characterisation of a CD+CD25highFOXP3 regulatory T cell population in the dog

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Fatty Liver Disease

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Small Cell Lung Cancer

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The genomic conservation of <i>foxp3</i> with its downstream flanking genes, <i>cacna1f</i> and <i>ccdc22</i>.

<p>The genomic conservation of <i>foxp3</i> with its downstream flanking genes, <i>cacna1f</i> and <i>ccdc22</i>.</p

The genomic context of avian <i>foxp3</i>.

<p>(A) The gene neighbourhood of <i>foxp3 in</i> a number of archosaurs showing the significant masked repeats of the American crow between <i>hsd17b10</i> and <i>cacna1f</i> (gaps in the line indicate intergenic repeat regions), the approximate location of the <i>foxp3</i> locus in the saker and peregrine falcon (marked by a pink arrow with a dashed line), and the low nucleotide sequence identity of <i>foxp3</i> between the American alligator and the ground tit. In the displayed region the overall masked repeats are as follows: 54.7% in the American crow, 28.0% in the saker falcon, 31.4% in the peregrine falcon, 6.8% in the ground tit and 0.02% in the American alligator. (B) The <i>foxp3</i> gene neighbourhood of the mouse, American alligator and ground tit, showing the gene variation upstream of <i>foxp3</i> in mammals, birds and crocodilians and the low nucleotide sequence identity of murine <i>foxp3</i> versus the American alligator and ground tit. (C) A comparison of the approximate <i>foxp3</i> loci in both falcons with the ground tit <i>foxp3 locus</i>, showing masked repeats (gaps in the line) and predicted exons (rectangles). All subfigures were produced using Easyfig [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150988#pone.0150988.ref047" target="_blank">47</a>] with BLASTN identity comparisons indicated by the scales on each subfigure.</p

A summary of the structural domains and regions of FoxP3 in different clades of the Animal Kingdom.

<p>A summary of the structural domains and regions of FoxP3 in different clades of the Animal Kingdom.</p

Alignment of the forkhead domain of FoxP3 and FoxP3-like proteins, highlighting mammalian and avian signature residues.

<p>The consistent exon boundaries in the ground tit and peregrine falcon were used to curate the gap within the sequence of the saker falcon. The mouse sequence is used as the baseline sequence and only amino acids in other sequences that differ are shown.</p