The genomic context of avian <i>foxp3</i>.

Abstract

<p>(A) The gene neighbourhood of <i>foxp3 in</i> a number of archosaurs showing the significant masked repeats of the American crow between <i>hsd17b10</i> and <i>cacna1f</i> (gaps in the line indicate intergenic repeat regions), the approximate location of the <i>foxp3</i> locus in the saker and peregrine falcon (marked by a pink arrow with a dashed line), and the low nucleotide sequence identity of <i>foxp3</i> between the American alligator and the ground tit. In the displayed region the overall masked repeats are as follows: 54.7% in the American crow, 28.0% in the saker falcon, 31.4% in the peregrine falcon, 6.8% in the ground tit and 0.02% in the American alligator. (B) The <i>foxp3</i> gene neighbourhood of the mouse, American alligator and ground tit, showing the gene variation upstream of <i>foxp3</i> in mammals, birds and crocodilians and the low nucleotide sequence identity of murine <i>foxp3</i> versus the American alligator and ground tit. (C) A comparison of the approximate <i>foxp3</i> loci in both falcons with the ground tit <i>foxp3 locus</i>, showing masked repeats (gaps in the line) and predicted exons (rectangles). All subfigures were produced using Easyfig [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150988#pone.0150988.ref047" target="_blank">47</a>] with BLASTN identity comparisons indicated by the scales on each subfigure.</p

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