Reflexões sobre o comércio contemporâneo: Reflections on contemporary commerce

Nesse artigo será apresentada a origem do comércio a fim de entender um pouco sobre a sua evolução até os dias atuais, conhecido também por e-commerce. O comércio eletrônico incide na aquisição e venda de serviços e produtos ou por intermédio de meios eletrônicos oriundos da internet. Este trabalho descreve como problema de pesquisa, entender sobre a evolução do comércio ao e-commerce. Os objetivos serão: apresentar as características da temática “comércio”; indicar as peculiaridades da internet e; esclarecer a importância do e-commerce. A metodologia apresentada consistirá na análise bibliográfica, acompanhada por consultas de artigos científicos, legislações e livros vinculados as temáticas abordadas. Este estudo é de aplicabilidade a pesquisadores, que podem examinar outras linhas de pesquisa a partir dos resultados encontrados

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Arq Neuropsiquiatr

p.982-985Objective: To evaluate the frequency of anxiety and depression disorders in patients with chronic pain. Method: Patients receiving care at the pain clinic of the Federal University of Bahia between February 2003 and November 2006. The MINI PLUS – Mini International Neuropsychiatric Interview was used to evaluate the patients and establish psychiatric diagnoses. Results: 400 patients were evaluated mean age was 45.6±11.37 years; 82.8% were female, 17.3% male; 48.5% were married; 55.1% were Catholics; and 40.5% had only high school education. Of these 29.9% reported intense pain and 70.8% reported suffering pain daily. The most frequent medical diagnosis was herniated disc (24.5%), and 48.5% of patients had been undergoing treatment at the pain clinic for less than 3 months. Comorbidities found were depressive episodes (42%), dysthymia (54%), social phobia (36.5%), agoraphobia (8.5%) and panic disorder (7.3%). Conclusion: Psychiatric comorbidities are prevalent in patients suffering chronic pain.São Paul

Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification

International audienc

CALR-mutated patients with low allele burden represent a specific subtype of essential thrombocythemia: A study on behalf of FIM and GBMHM.

International audienc