Promotion du dépistage des infections à Chlamydia Trachomatis auprès des adolescents: une revue de littératiure étoffée

Ce travail a pour but d’effectuer un état des lieux des connaissances et des méthodes actuelles sur la promotion du dépistage de la CT. De plus, il est intéressant de savoir quelle est l’investissement ainsi que le rôle de l’infirmier face à cette problématique ceci afin de trouver des stratégies permettant d’adapter le rôle et la pratique infirmière et d’intégrer de nouvelles approches pour le métier

LA SALUD MENTAL DE PACIENTES DERMATOLÓGICOS EN ATENDIMENTO HOSPITALAR

Delimitando e protegendo a individualidade, a pele é o principal meio de contato do sujeito com o mundo exterior. Conflitos e emoções podem se manifestar através do corpo e da pele, tornando-se visíveis e suscetíveis às reações sociais que muitas vezes são de preconceito e discriminação. O impacto dessas relações pode intensificar sintomas psicossomáticos e desencadear comorbidades como ansiedade e depressão, interferindo diretamente na qualidade de vida dos pacientes dermatológicos. Mesmo que as manifestações dermatológicas não sejam desencadeadas por fatores psíquicos, podem ser agravadas por estes, alterando a resposta do organismo a tratamentos. Há que se considerar ainda, que algumas doenças podem resultar da pobreza e prevalecer nestas condições, ou ainda gerar pobreza, colaborando para a manutenção da desigualdade social. Uma revisão bibliográfica foi realizada com o intuito de compreender o impacto psicológico das dermatoses na qualidade de vida dos acometidos. Considerando o cuidado que estes pacientes devem receber para que tenham uma melhora em sua relação consigo e com o meio social, contribuindo para a melhoria da sua qualidade de vida, a revisão bibliográfica abrangeu os métodos de intervenção psicossocial de Cinematerapia e de Rodas de Conversa, como estratégia terapêutica complementar dentro do ambiente hospitalar. Por meio de filmes que são ferramentas acessíveis, é possível propor reflexões sobre o tema, com debates sobre autoimagem, autoestima e aceitação, permitindo espaço para acolhimento e troca de vivências.Delimiting and protecting the individuality, the skin is the main means of contact of the subject with the outside world. Conflicts and emoticons may manifest themselves through the body and skin, becoming visible and susceptible to social reactions that are often of prejudice and discrimination. The impact of these relations can intensify psychosomatic symptoms and trigger comorbidities such as anxiety and depression, directly interfering in the quality of life of dermatological patients. Even if the dermatological manifestations are not triggered by psychic factors, they can be aggravated by these, altering the body's response to treatments. It should also be considered that some diseases may arise from poverty and prevail in these conditions, or even generate poverty, contributing to the maintenance of social inequality. A literature review was carried out in order to understand the psychological impact of dermatosis on the quality of life of those affected. Considering the care these patients should receive to improve their relationship with themselves and with the social environment, contributing to the improvement of their quality of life, the literature review covered the psychosocial intervention methods of Cinematherapy and Dialogue circles, as complementary therapeutic strategies within the hospital environment. Through films that are accessible tools, it is possible to propose reflections on the theme, with debates about self-image, self-esteem and acceptance, allowing space for welcoming and exchanging experiences.Delimitando y protegiendo la individualidad, la piel es el principal medio de contacto del sujeto con el mundo exterior. Conflictos y emociones pueden manifestarse a través del cuerpo y de la piel, tornándose visibles y susceptibles a reacciones sociales en muchos casos prejuiociosas y discriminatorias. El impacto de estas relaciones puede intensificar síntomas psicossomáticos y desencadenar comorbilidades como ansiedad y depresión, de esta forma impactando directamente en la calidad de vida de los pacientes dermatológicos. Aun en los casos en que las manifestaciones dermatológicas no tengan como causa factores psíquicos, pueden ser agravadas por los mismos, alterando la respuesta del organismo a los tratamientos.  Se debe considerar también que algunas enfermedades pueden ser resultado de condiciones de pobreza y prevalecer en estas condiciones, o en algunos casos intensificar estas condiciones de vulnerabilidad, colaborando para el mantenimiento de la desigualdad social. Fue realizada una revisión de bibliografía con la intención de comprender el impacto psicológico de las dermatosis en la calidad de vida de los afectados. Considerando el cuidado que estos pacientes deben recibir para que evidencien una mejora en su relación consigo e con su medio social, contribuyendo para una mejora de su calidad de vida, la revisión bibliográfica abarcó los métodos de intervención psicosocial de Cinematerapia y Rondas de conversación, como estrategia terapéutica complementar dentro del ambiente hospitalar. A través de películas, que son recursos accesibles, es posible proponer reflexiones sobre el tema, incluyendo debates sobre auto-imagen, autoestima y aceptación, promoviendo un espacio de acogida e intercambio de vivencias

Supplement 1: Two-photon instant structured illumination microscopy improves the depth penetration of super-resolution imaging in thick scattering samples

Originally published in Optica on 20 September 2014 (optica-1-3-181

Effective Taxation of Top Incomes in Germany, 1992-2002

We analyze the taxation of top personal incomes in Germany on the basis of an integrated data file of individual tax returns and a general household survey for the years 1992 - 2002. The unique feature of this integrated data set is that it includes all taxpayers in the top percentile of the gross income distribution. We show that despite substantial tax base erosion and significant reductions of top statutory marginal tax rates, German income taxation has remained effectively progressive. The distribution of the tax burden is highly concentrated, and the effective average income tax rate of the German economic elite - the top 0.001 quantile of the gross income distribution - is about 34 percent, which is well below the legislated tax rate

Persistently high IgA serum levels are a marker of immunological or virological failure of combined antiretroviral therapy in children with perinatal HIV-1 infection

Non-expensive and low-complexity surrogate markers for monitoring the response to combined antiretroviral therapy (combined-ART) are needed in poor-resource settings where routine assessment of CD4+ T-lymphocyte count and viral load can not be afforded. We longitudinally evaluated Ig serum levels in 234 HIV-1 infected children receiving combined-ART with ≥ 3 drugs. Since Ig levels physiologically vary with age, differences at different age periods were evaluated as differences in z-scores calculated using the mean and standard deviation of the normal population for each age period. Data from 17 (7·3%) children with immunological failure and from 54 (23·1%) children with virological failure of combined-ART were compared with data from not-failed children. At baseline children with immunological failure showed higher IgM z-scores (P = 0·042) than children without. After 3–12 months of therapy immunologically failed children displayed higher viral loads (P < 0·0001) and IgA (P = 0·043) z-scores than not-failed children. Similarly, at the same follow-up time, children with virological failure showed lower CD4+ T-lymphocyte percentages (P = 0·005) and higher IgA z-scores (P < 0·0001) than not-failed children. No difference in IgG or IgM z-scores was evidenced between failed and not-failed children after 3–12 months of therapy. In conclusion, IgA serum level is a cheap and low-complexity marker of immunological or virological failure of combined-ART which might be adopted in poor-resource settings

Early triple therapy vs mono or dual therapy for children with perinatal HIV infection.

none91The time at which antiretroviral therapy (ART) should be initiated in children with perinatal human immunodeficiency virus (HIV) infection remains controversial. In a cohort study, Berk et al1 reported clinical benefit from mono/dual ART started before 60 days of life in 10 children compared with treatment administered at 61 to 120 days of life in 16 children. The 23 children who received early triple ART were not investigated because none of them progressed to category C diagnosis by 3 years of age. We performed a similar analysis in a cohort study of a larger data set of children with a longer follow-up to evaluate the outcomes of early and very early triple ART.noneChiappini E; Galli L; Gabiano C; Tovo PA; de Martino M; P.Osimani; R. Cordiali; D. De Mattia; M. Manzionna; C. Di Bari; M. Ruggeri; M.Masi; A. Miniaci; F. Specchia; M. Ciccia; M. Lanari; F. Baldi; L. Battisti; C. Fiorino; C.Dessı`; C. Pintor; M. Dedoni; M.L. Fenu; R. Cavallini; E. Anastasio; F. Merolla; M. Sticca; G. Pomero; T. Bezzi; E. Fiumana; F. Bonsignori; P. Gervaso; E. Seini; M.T. Cecchi; D. Cosso; A. Timitilli; M.Stronati; A. Plebani; R. Pinzani; I. Bongianin; A.Vigano`; V. Giacomet; P. Erba; F. Salvini; G.V. Zuccotti; M. Giovannini; G. Ferraris; R. Lipreri; C. Moretti; M. Cellini; M.C. Cano; P. Paolucci; E. Bruzzese; G. De Marco; L. Tarallo; F. Tancredi; M. Pennazzato;O. Rampon; E.R. Dalle Nogare; A. Sanfilippo; A.Romano; M. Saitta; I. Dodi; A. Barone; A. Maccabruni; R. Consolini; A. Legitimo; C. Magnani; P. Falconieri; C. Fundaro`; O.Genovese; A. Panzanella; A.M. Casadei; A. Martino;C. Concato; G. Anzidei; G. Bove; S. Cerilli; S. Catania;C. Ajassa; A. Ganau; L. Cristiano; A. Mazza; A. Di Palma; F. Mignone; C. Riva; C. Scorfaro; V. Portelli; M. Rabusin; A. Pellegatta; M. MolesiniChiappini, E; Galli, L; Gabiano, C; Tovo, Pa; de Martino, M; P., Osimani; R., Cordiali; D., De Mattia; M., Manzionna; C., Di Bari; M., Ruggeri; M., Masi; A., Miniaci; F., Specchia; M., Ciccia; M., Lanari; F., Baldi; L., Battisti; C., Fiorino; C., Dessı`; C., Pintor; M., Dedoni; M. L., Fenu; R., Cavallini; E., Anastasio; F., Merolla; M., Sticca; G., Pomero; Bezzi, Teresa Maria; Fiumana, Elisa; F., Bonsignori; P., Gervaso; E., Seini; M. T., Cecchi; D., Cosso; A., Timitilli; M., Stronati; A., Plebani; R., Pinzani; I., Bongianin; A., Vigano`; V., Giacomet; P., Erba; F., Salvini; G. V., Zuccotti; M., Giovannini; G., Ferraris; R., Lipreri; C., Moretti; M., Cellini; M. C., Cano; P., Paolucci; E., Bruzzese; G., De Marco; L., Tarallo; F., Tancredi; M., Pennazzato; O., Rampon; E. R., Dalle Nogare; A., Sanfilippo; A., Romano; M., Saitta; I., Dodi; A., Barone; A., Maccabruni; R., Consolini; A., Legitimo; C., Magnani; P., Falconieri; C., Fundaro`; O., Genovese; A., Panzanella; A. M., Casadei; A., Martino; C., Concato; G., Anzidei; G., Bove; S., Cerilli; S., Catania; C., Ajassa; A., Ganau; L., Cristiano; A., Mazza; A., Di Palma; F., Mignone; C., Riva; C., Scorfaro; V., Portelli; M., Rabusin; A., Pellegatta; M., Molesin

Cancer rates after year 2000 significantly decrease in children with perinatal HIV infection: a study by the Italian Register for HIV Infection in Children

PURPOSE: To evaluate the impact of highly active antiretroviral therapy (HAART) on cancer incidence in HIV-infected children throughout a 20-year period. PATIENTS AND METHODS: An observational population study was conducted on 1,190 perinatally HIV-infected children enrolled onto the Italian Register for HIV Infection in Children from 1985 to 2004 and never lost to follow-up (total observation time, 10,037.66 years). Cancer rates were calculated in the pre-HAART (1985 to 1995), early HAART (1996 to 1999), and late HAART (2000 to 2004) periods and compared using Poisson regression adjusted for age. The proportion of HAART-treated children increased from 4.1% in 1996 to 60.4% in 1999 and to 81.5% in 2004. In the same time frame, the proportion of children receiving HAART for at least 2 years increased from 3.1% to 77.0%. RESULTS: Overall, 35 cancers occurred. Cancer rates were 4.49 (95% CI, 2.37 to 6.64), 4.09 (95% CI, 1.68 to 6.50), and 0.76 (95% CI, 0.00 to 1.80) per 1,000 children per year in 1985 to 1995, 1996 to 1999, and 2000 to 2004, respectively. Notably, there was no significant difference comparing the periods from 1985 to 1995 and 1996 to 1999 (P = .081). By contrast, cancer rates were significantly lower in the period from 2000 to 2004 than in 1996 to 1999 (P < .0001). Results were confirmed by separately analyzing data from children observed from birth (P = .418 for 1985 to 1995 v 1996 to 1999; P = .001 for 1996 to 1999 v 2000 to 2004). CONCLUSION: Dramatically reduced cancer rates were observed only in the late HAART period in parallel to the increasing proportion of children receiving HAART therapy

Cancer rates after year 2000 significantly decrease in children with perinatal HIV infection: a study by the Italian Register for HIV Infection in Children.

PURPOSE: To evaluate the impact of highly active antiretroviral therapy (HAART) on cancer incidence in HIV-infected children throughout a 20-year period. PATIENTS AND METHODS: An observational population study was conducted on 1,190 perinatally HIV-infected children enrolled onto the Italian Register for HIV Infection in Children from 1985 to 2004 and never lost to follow-up (total observation time, 10,037.66 years). Cancer rates were calculated in the pre-HAART (1985 to 1995), early HAART (1996 to 1999), and late HAART (2000 to 2004) periods and compared using Poisson regression adjusted for age. The proportion of HAART-treated children increased from 4.1% in 1996 to 60.4% in 1999 and to 81.5% in 2004. In the same time frame, the proportion of children receiving HAART for at least 2 years increased from 3.1% to 77.0%. RESULTS: Overall, 35 cancers occurred. Cancer rates were 4.49 (95% CI, 2.37 to 6.64), 4.09 (95% CI, 1.68 to 6.50), and 0.76 (95% CI, 0.00 to 1.80) per 1,000 children per year in 1985 to 1995, 1996 to 1999, and 2000 to 2004, respectively. Notably, there was no significant difference comparing the periods from 1985 to 1995 and 1996 to 1999 (P = .081). By contrast, cancer rates were significantly lower in the period from 2000 to 2004 than in 1996 to 1999 (P < .0001). Results were confirmed by separately analyzing data from children observed from birth (P = .418 for 1985 to 1995 v 1996 to 1999; P = .001 for 1996 to 1999 v 2000 to 2004). CONCLUSION: Dramatically reduced cancer rates were observed only in the late HAART period in parallel to the increasing proportion of children receiving HAART therapy