Droplet impact and penetration on series of parallel tubes

Impact and penetration of a liquid droplet on a substrate having a line of parallel capillary openings drilled along its thickness is experimentally studies. Different regimes of droplet penetration are identified. At low impact velocities, the droplet impacts on the substrate, spreads, and penetrates into the substrate mainly due to the capillary action in each tubular hole. At higher impact velocities, the droplet impacts on the substrate, spreads and penetrates due to the droplet inertia, and then penetrates further due to the capillary action. Threshold velocities for liquid penetration into capillary tubes are identified. Two penetration regimes, capillary and inertia driven regimes, have been studied extensively for a range of parameters related to droplet impact on a line of parallel capillary openings. Index Terms—Droplet impact, parallel capillary tubes, penetration, liquid spread

Hubungan Kinerja Otak Dengan Spiritualitas Manusia Diukur Dengan Menggunakan Indonesia Spiritual Health Assessment Pada Dosen Stain Manado

: Neuroscience is a science about the nervous system especially the brain. According to Daniel Amen who used SPECT to watch brain activity that was associated with the soul, brain was divided into five main systems: prefrontal cortex, limbic system, ganglia basalis, gyrus cingulatus, and temporal lobe. A person's spirituality is related to the purpose and meaning of his/her life as a manifestation of one's relationship with God. Spirituality has four dimensions, namely the meaning of life, positive emotions, spiritual experiences and rituals. In Indonesia, Indonesia Spiritual Health Assessment (ISHA) is used to assess a person's spirituality. The purpose of this research was to determine the relationship of spirituality with the human brain among Manado STAIN lecturers. This was a descriptive analytic study with 30 respondents. The results were analyzed by using the Spearmen correlation analysis. There was a significant correlation between the performance of the human brain and spirituality, in this case the relationship was between the prefrontal cortex and the meaning of life. Conclusion: There was a strong relationship between the human brain and spirituality

Bell�s palsy following growth hormone therapy in a patient with Prader-Willi syndrome: The first report

Prader�Willi Syndrome (PWS) is a complex genetic disorder with different manifestations in infancy and childhood including obesity, type 2 diabetes mellitus, mild to moderate intellectual impairment and learning disabilities. In this syndrome, growth hormone therapy improves outcomes. For the first time, here we report an 11-year-old boy with PWS who presented with three episodes of unilateral facial palsy after starting growth hormone therapy. © 2017 The Authors

Seismic response evaluation of RC tower connected to short rigid buildings.

In urban construction with the presence of tall buildings adjacent to short buildings, civil engineers have tried to connect low-rise rigid buildings to tall buildings in order to enhance the rigidity of the towers and decrease seismic response induced by earthquake excitation. From recent developments in earthquake energy dissipation systems, the application of viscous dampers for coupling of parallel and adjacent buildings to reduce earthquake effect has been considered by civil engineers, and many investigations have been conducted. In the present study an attempt has been made to evaluate the effect of connecting reinforced concrete towers to short rigid building through viscous damper devices. For this purpose, a 10-story RC tower connected to two short RC buildings by viscous damper was modeled and analyzed under Elcentro (1940) earthquake record excitation by using the finite element technique. In addition, the effect of various viscous damper damping coefficients on seismic response of the tower was evaluated by analyzing the aforementioned tower with various damper damping coefficient to the short building. The results showed improvement of seismic response of the tall building which was supported by short RC buildings through viscous damper device during earthquake. Moreover by increasing damper damping coefficient response of the tower structure the displacement was effectively reduced

Who is accessing community lateral flow device testing and why:Characteristics and motivations of individuals participating in COVID-19 community testing in two English local authority areas

BACKGROUND: Antigen testing using lateral flow devices (LFDs) plays an important role in the management of the novel coronavirus pandemic of 2019 (COVID-19) by rapidly identifying individuals who are asymptomatically carrying high levels of the virus. By January 2021, LFD community testing sites were set up across English local authority areas to support the management and containment of regional COVID-19 cases, initially targeting essential workers unable to work from home during the national lockdown. This study aimed to examine the characteristics and motivations of individuals accessing community LFD testing across two local authority areas (LAAs) in the South West of England. METHODS: Data were collected as part of a service evaluation from December 22(nd) 2020 until March 15(th) 2021 for two LAAs. Demographic and postcode data were collected from an online test appointment booking platform and the National Health Service testing service online system, with data accessed from Public Health England. An online survey was sent to individuals who made a testing appointment at an LAA1 site using the online booking platform, consisting of 12 questions to collect data on individual’s motivations for and experiences of testing. RESULTS: Data were available for individuals who completed 12,516 tests in LAA1 and 12,327 tests in LAA2. Most individuals who engaged with testing were female, working age, white, and worked as early years or education staff, health and social care staff, and supermarket or food production staff. 1249 individuals completed the survey with 60% of respondents reported getting tested for work-related reasons. Individuals first heard about LFD testing through various channels including work, media, and word of mouth, and decided to get tested based on the ease and convenience of testing, workplace communications, and to identify asymptomatic cases to help stop the spread. Most tests were completed by individuals living in less deprived areas based on national deciles of deprivation. CONCLUSIONS: While national and local COVID-19 testing strategies have evolved, community and personal LFD testing remains a crucial pillar of the testing strategy. Future studies should collect quantitative and qualitative data from residents to most effectively shape testing offers based on the needs and preferences of their population. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-12986-4

A novel pathogenic variant of SRD5A2 in an Iranian psuedohermaphrodite male

Deficiency of the 5-alpha-reductase may have an important role in 46,XY DSD in some cohorts. The prenatal ultrasonography and karyotyping can trigger the attention toward the presence of a DSD in fetus. © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Lt

Identification of a novel KCNQ1 frameshift mutation and review of the literature among iranian long QT families

Background: Long QT syndrome (LQTS) is characterized by the prolongation of QT interval, which results in syncope and sudden cardiac death in young people. KCNQ1 is the most common gene responsible for this syndrome. Methods: Molecular investigation was performed by DNA Sanger sequencing in Iranian families with a history of syncope. In silico examinations were performed for predicting the pathogenicity of the novel variant. Results: A novel homozygous KCNQ1 frameshift mutation, c.14261429delATGC (M476Pfs*4), was identified, and then the current literatures of five patients were reviewed regarding the LQTS. Conclusion: The novel frameshift mutation has been reported for the first time among the Iranian population. Our finding along with the case series study of LQTS patients illustrates the importance of genetic and case series in precise detection of the frequency of LQTS carrierscarriers. © 2019, Pasteur Institute of Iran. All rights reserved

Novel frameshift mutation in the KCNQ1 gene responsible for jervell and lange-nielsen syndrome

Objective(s): Jervell and Lange�Nielsen syndrome is an autosomal recessive disorder caused by mutations in KCNQ1 or KCNE1 genes. The disease is characterized by sensorineural hearing loss and long QT syndrome. Materials and Methods Here we present a 3.5-year-old female patient, an offspring of consanguineous marriage, who had a history of recurrent syncope and congenital sensorineural deafness. The patient and the family members were screened for mutations in KCNQ1 gene by linkage analysis and DNA sequencing. Results: DNA sequencing showed a c.15321534delG (p. A512Pfs*81) mutation in the KCNQ1 gene in homozygous form. The results of short tandem repeat (STR) markers showed that the disease in the family is linked to the KCNQ1 gene. The mutation was confirmed in the parents in heterozygous form. Conclusion: This is the first report of this variant in KCNQ1 gene in an Iranian family. The data of this study could be used for early diagnosis of the condition in the family and genetic counseling. © 2018, Mashhad University of Medical Sciences. All rights reserved