Nonflammable, antistatic, and heat-sealable film

Antistatic, heat-sealable, nonflammable films prepared from polyvinylidene fluoride and polyvinylidene chloride resin

Convolutional LSTM Networks for Subcellular Localization of Proteins

Machine learning is widely used to analyze biological sequence data. Non-sequential models such as SVMs or feed-forward neural networks are often used although they have no natural way of handling sequences of varying length. Recurrent neural networks such as the long short term memory (LSTM) model on the other hand are designed to handle sequences. In this study we demonstrate that LSTM networks predict the subcellular location of proteins given only the protein sequence with high accuracy (0.902) outperforming current state of the art algorithms. We further improve the performance by introducing convolutional filters and experiment with an attention mechanism which lets the LSTM focus on specific parts of the protein. Lastly we introduce new visualizations of both the convolutional filters and the attention mechanisms and show how they can be used to extract biological relevant knowledge from the LSTM networks

Semiclassical Distorted Wave Model Analysis of the (π−,K+)(\pi^-,K^+) Σ\Sigma Formation Inclusive Spectrum

$(\pi^-,K^+)$ hyperon production inclusive spectra with $p_\pi =1.2$ GeV/c measured at KEK on $^{12}$C and $^{28}$Si are analyzed by the semiclassical distorted wave model. Single-particle wave functions of the target nucleus are treated using Wigner transformation. This method is able to account for the energy and angular dependences of the elementary process in nuclear medium without introducing the factorization approximation frequently employed. Calculations of the $(\pi^+,K^+)$ $\Lambda$ formation process, for which there is no free parameter since the $\Lambda$ s.p. potential is known, demonstrate that the present model is useful to describe inclusive spectra. It is shown that in order to account for the experimental data of the $\Sigma^-$ formation spectra a repulsive $\Sigma$-nucleus potential is necessary whose magnitude is not so strong as around 100 MeV previously suggested.Comment: 12 pages, 10 figures, accepted in Phys. Rev.

Measurement of Spin Correlation Parameters ANN_{NN}, ASS_{SS}, and A_SL{SL} at 2.1 GeV in Proton-Proton Elastic Scattering

At the Cooler Synchrotron COSY/J\"ulich spin correlation parameters in elastic proton-proton (pp) scattering have been measured with a 2.11 GeV polarized proton beam and a polarized hydrogen atomic beam target. We report results for A$_{NN}$, A$_{SS}$, and A_${SL}$ for c.m. scattering angles between 30$^o$ and 90$^o$. Our data on A$_{SS}$ -- the first measurement of this observable above 800 MeV -- clearly disagrees with predictions of available of pp scattering phase shift solutions while A$_{NN}$ and A_${SL}$ are reproduced reasonably well. We show that in the direct reconstruction of the scattering amplitudes from the body of available pp elastic scattering data at 2.1 GeV the number of possible solutions is considerably reduced.Comment: 4 pages, 4 figure

Change of the ice rheology with climatic transitions – implication on ice flow modelling and dating of the EPICA Dome C core

International audienceThe study of the distribution of the crystallographic orientations (the fabric) along ice cores supplies information on the past and current ice flows of ice-sheets. Beside the usually observed formation of a vertical single maximum fabric, the EPICA Dome Concordia ice core (EDC) shows an abrupt and unexpected strenghtening of its fabric during termination II around 1750 m depth. Such strengthenings were already observed for sites located on an ice-sheet. This suggests that horizontal shear could occur along the EDC core. Moreover, the change in the fabric leads to a modification of the viscosity between neighbouring ice layers. Through the use of an anisotropic ice flow model, we quantify the change in viscosity and investigate its implication on ice flow and dating

Change in ice rheology during climate variations – implications for ice flow modelling and dating of the EPICA Dome C core

The study of the distribution of crystallographic orientations (i.e., the fabric) along ice cores provides information on past and current ice flow in ice-sheets. Besides the usually observed formation of a vertical single maximum fabric, the EPICA Dome C ice core (EDC) shows an abrupt and unexpected strengthening of its fabric during termination II around 1750 m depth. Such strengthening has already been observed for sites located on an ice-sheet flank. This suggests that horizontal shear could occur along the EDC core. Moreover, the change in the fabric leads to a modification of the effective viscosity between neighbouring ice layers. Through the use of an anisotropic ice flow model, we quantify the change in effective viscosity and investigate its implication for ice flow and dating

Inter-laboratory comparison of methods to measure androstenone in pork fat

Today, different analytical methods are used by different laboratories to quantify androstenone in fat tissue. This study shows the comparison of methods used routinely in different laboratories for androstenone quantification: Time-resolved fluoroimmunoassay in Norwegian School of Veterinary Science (NSVS; Norway), gas chromatography coupled to mass spectrometry in Co-operative Central Laboratory (CCL; The Netherlands) and in Institut de Recerca i Tecnologia Agroalimentàries (IRTA; Spain), and high-pressure liquid chromatography in Agroscope Liebefeld-Posieux Research Station (ALP; Switzerland). In a first trial, a set of adipose tissue (AT) samples from 53 entire males was sent to CCL, IRTA and NSVS for determination of androstenone concentration. The average androstenone concentration (s.d.) was 2.47 (2.10) μg/g at NSVS, 1.31 (0.98) μg/g at CCL and 0.62 (0.52) μg/g at IRTA. Despite the large differences in absolute values, inter-laboratory correlations were high, ranging from 0.82 to 0.92. A closer look showed differences in the preparation step. Indeed, different matrices were used for the analysis: pure fat at NSVS, melted fat at CCL and AT at IRTA. A second trial was organised in order to circumvent the differences in sample preparation. Back fat samples from 10 entire males were lyophilised at the ALP labortary in Switzerland and were sent to the other laboratories for androstenone concentration measurement. The average concentration (s.d.) of androstenone in the freeze-dried AT samples was 0.87 (0.52), 1.03 (0.55), 0.84 (0.46) and 0.99 (0.67) μg/g at NSVS, CCL, IRTA and ALP, respectively, and the pairwise correlations between laboratories ranged from 0.92 to 0.97. Thus, this study shows the influence of the different sample preparation protocols, leading to major differences in the results, although still allowing high inter-laboratory correlations. The results further highlight the need for method standardisation and inter-laboratory ring tests for the determination of androstenone. This standardisation is especially relevant when deriving thresholds of consumer acceptance, whereas the ranking of animals for breeding purposes will be less affected due to the high correlations between method

A New Non-Perturbative Approach to Quantum Theory in Curved Spacetime Using the Wigner Function

A new non-perturbative approach to quantum theory in curved spacetime and to quantum gravity, based on a generalisation of the Wigner equation, is proposed. Our definition for a Wigner equation differs from what have otherwise been proposed, and does not imply any approximations. It is a completely exact equation, fully equivalent to the Heisenberg equations of motion. The approach makes different approximation schemes possible, e.g. it is possible to perform a systematic calculation of the quantum effects order by order. An iterative scheme for this is also proposed. The method is illustrated with some simple examples and applications. A calculation of the trace of the renormalised energy-momentum tensor is done, and the conformal anomaly is thereby related to non-conservation of a current in d=2 dimensions and a relationship between a vector and an axial-vector current in d=4 dimensions. The corresponding ``hydrodynamic equations'' governing the evolution of macroscopic quantities are derived by taking appropriate moments. The emphasis is put on the spin-1/2 case, but it is shown how to extend to arbitrary spins. Gravity is treated first in the Palatini formalism, which is not very tractable, and then more successfully in the Ashtekar formalism, where the constraints lead to infinite order differential equations for the Wigner functions.Comment: LaTeX2e (uses amssymb), 36 page

Testing one-body density functionals on a solvable model

There are several physically motivated density matrix functionals in the literature, built from the knowledge of the natural orbitals and the occupation numbers of the one-body reduced density matrix. With the help of the equivalent phase-space formalism, we thoroughly test some of the most popular of those functionals on a completely solvable model.Comment: Latex, 16 pages, 4 figure

High tibial osteotomy in Sweden, 1998–2007: A population-based study of the use and rate of revision to knee arthroplasty

To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field.Most studies on high tibial osteotomies (HTOs) have been hospital-based and have included a limited number of patients. We evaluated the use and outcome-expressed as rate of revision to knee arthroplasty-of HTO performed in Sweden with 9 million inhabitants, 1998-2007. 3, 161 HTO procedures on patients 30 years or older (69% men) who were operated on for knee osteoarthritis in Sweden, 1998-2007, were identified through the inpatient and outpatient care registers of the Swedish National Board of Health and Welfare. Pertinent data were verified through surgical records. Conversions of HTO to knee arthroplasty before 2010 were identified through the Swedish Knee Arthroplasty Register (SKAR). The 10-year survival was determined using revision to an arthroplasty as the endpoint. The number of HTOs decreased by one third between 1998 and 2007, from 388 operations a year to 257 a year. Most of the HTOs were performed with open wedge osteotomy using external fixation. The cumulative revision rate at 10 years was 30% (95% CI: 28-32). The risk of revision increased with increasing age and was higher in women than in men (RR = 1.3, CI: 1.1-1.5). If being without an artificial joint implant is considered to be beneficial, then HTO is an excellent alternative to knee arthroplasty in younger and/or physically active patients suffering from knee osteoarthritis.Swedish Research Council Swedish Rheumatism Association King Gustaf V 80-year Birthday Fund Faculty of Medicine, Lund University Region Skan