1,480 research outputs found
Characterization of the volatile fraction emitted by phloems of four pinus species by solid-phase microextraction and gas chromatography–mass spectrometry
Pine forests constitute some of the most important renewable resources supplying timber, paper and chemical industries, among other functions. Characterization of the volatiles emitted by different Pinus species has proven to be an important tool to decode the process of host tree selection by herbivore insects, some of which cause serious economic damage to pines. Variations in the relative composition of the bouquet of semiochemicals are responsible for the outcome of different biological processes, such as mate finding, egg-laying site recognition and host selection. The volatiles present in phloem samples of four pine species, P. halepensis, P. sylvestris, P. pinaster and P. pinea, were identified and characterized with the aim of finding possible host-plant attractants for native pests, such as the bark beetle Tomicus piniperda. The volatile compounds emitted by phloem samples of pines were extracted by headspace solid-phase micro extraction, using a 2 cm 50/30 mm divinylbenzene/carboxen/polydimethylsiloxane table flex solid-phase microextraction fiber and its contents analyzed by high-resolution gas chromatography, using flame ionization and a non polar and chiral column phases. The components of the volatile fraction emitted by the phloem samples were identified by mass spectrometry using time-of-flight and quadrupole mass analyzers. The estimated relative composition was used to perform a discriminant analysis among pine species, by means of cluster and principal component analysis. It can be concluded that it is possible to discriminate pine species based on the monoterpenes emissions of phloem samples
The International development of PROQOL-HCV: An instrument to assess the health-related quality of life of patients treated for Hepatitis C virus
Background
Hepatitis C virus (HCV) compromises Health-related Quality of Life (HRQL) with detriments to Physical, Mental and Social health domains. Treatment with interferon and ribavirin is associated with side effects which further impair HRQL. New treatments appear potent, effective and tolerable. However, Patient Reported Outcomes instruments that capture the impact on HRQL for people with hepatitis C are largely non-specific and will be needed in the new treatment era. Therefore, we developed a conceptually valid multidimensional model of HCV-specific quality of life and pilot survey instrument, the Patient Reported Outcome Quality of Life survey for HCV (PROQOL-HCV).
Methods
HCV patients from France (n = 30), Brazil (n = 20) and Australia (n = 20) were interviewed to investigate HCV-HRQL issues raised in the scientific literature and by treatment specialists. Interviews were recorded, transcribed and translated into English and French.
Results
Fifteen content dimensions were derived from the qualitative analysis, refined and fitted to four domains: (1) Physical Health included: fatigue, pain, sleep, sexual impairment and physical activity; (2) Mental Health: psychological distress, psychosocial impact, and cognition; (3) Social Health: support, stigma, social activity, substance use; (4) Treatment: management, side effects, and fear of treatment failure. The impact of some dimensions extended beyond their primary domain including: physical activity, cognition, sleep, sexual impairment, and the three treatment dimensions. A bank of 300 items was constructed to reflect patient reports and, following expert review, reduced to a 72-item pilot questionnaire.
Conclusion
We present a conceptually valid multidimensional model of HCV-specific quality of life and the pilot survey instrument, PROQOL-HCV. The model is widely inclusive of the experience of hepatitis C and the first to include the treatment dimension
Validity And Reliability Of A Self-efficacy Expectancy Scale For Adherence To Antiretroviral Therapy For Parents And Carers Of Children And Adolescents With Hiv/aids [validação E Reprodutibilidade De Uma Escala De Auto-eficácia Para Adesão Ao Tratamento Anti-retroviral Em Pais Ou Cuidadores De Crianças E Adolescentes Vivendo Com Hiv/aids]
Objective: To validate and evaluate the reproducibility of a self-efficacy (SE) scale for adherence to antiretroviral therapy in children and adolescents with HIV/AIDS, taking into account the perspective of parents/guardians. Methods: The study was carried out at the Hospital-Dia, Centro de Referência e Treinamento em DST/AIDS (CRT/SP), in São Paulo, Brazil. The parents/guardians of 54 children and adolescents aged 6 months to 20 years were interviewed during routine consultations at our service. Data on SE were collected using the Self-Efficacy for Following Anti-Retroviral Prescription Scale, and SE scores were calculated in two different ways: factor analysis and a predefined formula. The scale's internal consistency was verified using Cronbach's α coefficient. Validity was tested by comparing the mean scores of a group of patients who did adhere to antiretroviral treatment with those of a group that did not (Mann-Whitney test) and by calculating the Spearman correlation coefficient for agreement between scores and clinical parameters. Reproducibility was verified using the Wilcoxon test, intraclass correlation coefficients (ricc) and Bland-Altman plots. Results: The SE scale demonstrated good internal consistency (α = 0.87) and good reproducibility (r icc = 0.69 and r icc = 0.75). In terms of validity, the SE scale was capable of differentiating adherent patients from those who did not adhere to their antiretroviral treatment (p = 0.002) and exhibited a significant correlation with CD4 counts (r = 0.28; p = 0.04). Conclusions: The SE scale can be used to assess adherence to antiretroviral therapy in children and adolescents with HIV/AIDS, taking into account the perspective of parents/carers. Copyright © 2008 by Sociedade Brasileira de Pediatria.8414146Matida, L.H., da Silva, M.H., Tayra, A., Succi, R.C., Gianna, M.C., Gonçalves, A., Prevention of mother-to-child transmission of HIV in São Paulo State, Brazil: An update (2005) AIDS, 19 (SUPPL. 4), pp. S37-S41Gibb, D.M., Goodall, R.L., Giacomet, V., McGee, L., Compagnucci, A., Lyall, H., Paediatric European Network for Treatment of Aids Steering Committee. Adherence to prescribed antiretroviral therapy in human immunodeficiency virus-infected children in the PENTA 5 trial (2003) Pediatr Infect Dis J, 22, pp. 56-62Pluciennik, A.M., (2003) Transmissão materno infantil do vírus da imunodeficiência humana adquirida: Quanto custa não prevenir [tese], , São Paulo: Faculdade de Saúde Pública da USP;Dyke, R.B.V., Lee, S., Johnson, G.M., Wiznia, A., Mohan, K., Stanley, K., Reported adherence as a determinant of response to highly active antiretroviral therapy in children who have human immunodeficiency virus infection (2002) Pediatrics, 109 (4), pp. 1-7Starace, F., Massa, A., Amico, K.R., Fisher, J.D., Adherence to antiretroviral therapy: An empirical test of the information-motivation-behavioral skills model (2006) Health Psychol, 25, pp. 153-162Shah, C.A., Adherence to high activity antiretroviral therapy (HAART) in pediatric patients infected with HIV: Issues and interventions (2007) Indian J Pediatr, 74, pp. 55-60Leite, J.C., Drachler, M.L., Centeno, M.O., Pinheiro, C.A., Silveira, V.L., Desenvolvimento de uma escala de auto-eficácia para adesão ao tratamento anti-retroviral. (2002) Psicol Reflex Crit, 15, pp. 121-133Bandura, A., Self-efficacy: Toward a unifying theory of behavioral change (1977) Psychol Rev, 84, pp. 191-215Gortmaker SL, Lenderking WR, Clark C, Lee S, Fowler MG, Oleske JMThe ACTG 219 Team. Development and use of a pediatric quality of life questionnaire in AIDS clinical trials: reliability and validity of the general health assessment for children. In: Drotar D. Measuring health-related quality of life in children and adolescents: implications for research and practice. Mahwah, NJ: Lawrence Erlbaum Associates1998. p. 219-35Eiser, C., Morse, R., Quality-of-life measures in chronic diseases of childhood (2001) Health Technol Assess, 5, pp. 1-95Streiner, D.L., Norman, G.R., (2003) Health measurement scales: A practical guide to their development and use, , 3rd ed. Oxford: Oxford University Press;Drotar D, Levi R. Critical issues and needs in health-related quality of life assessment of children and adolescents with chronic health condition. In: Drotar D. Measuring health-related quality of life in children and adolescents: implications for research and practice. Mahwah, NJ: Lawrence Erlbaum Associates1998. p. 3-2
Convergence of the critical attractor of dissipative maps: Log-periodic oscillations, fractality and nonextensivity
For a family of logistic-like maps, we investigate the rate of convergence to
the critical attractor when an ensemble of initial conditions is uniformly
spread over the entire phase space. We found that the phase space volume
occupied by the ensemble W(t) depicts a power-law decay with log-periodic
oscillations reflecting the multifractal character of the critical attractor.
We explore the parametric dependence of the power-law exponent and the
amplitude of the log-periodic oscillations with the attractor's fractal
dimension governed by the inflexion of the map near its extremal point.
Further, we investigate the temporal evolution of W(t) for the circle map whose
critical attractor is dense. In this case, we found W(t) to exhibit a rich
pattern with a slow logarithmic decay of the lower bounds. These results are
discussed in the context of nonextensive Tsallis entropies.Comment: 8 pages and 8 fig
Indicadores De Desempenho Motor Como Preditores De Fragilidade Em Idosos Cadastrados Em Uma Unidade De Saúde Da Família
This study aimed to identify the motor performance tests more strongly associated with frailty and respective cut-off points and verify the best motor performance indicator as screening tool to discriminate frailty in elderly registered in Family Health Unit Participated in the study 139 elderly aged ≥60 years 105 women and 34 men The frailty was identified by the criteria of Fried et al (2001) The motor performance tests realized were: Handgrip strength (HS) sit-to-stand test walk test (WT) and pick up a pen test Logistic regression analysis was used to associate the motor performance tests and frailty The cutoff points were evaluated by parameters provided by Receiver Operating Characteristic curve (ROC) with significance level of 5% Data were analyzed using SPSS 210 and MedCalc The mean age was 7232 ± 84 The walk test was positively associated with frailty (OR 130; p <001) and handgrip strength in elderly women was inversely associated with frailty on feminine sex (OR 074; p <0001) The WT presented a cutoff 5s (sensitivity 889 and specificity 745%) and the handgrip in the women obtained a cutoff point 146 kgf (sensitivity 833 and specificity 790%) It was concluded that the walk test was the best screening indicator to discriminate the frailty in elderly both sexes registered in a Family Health Unit. © Edições Desafio Singular.122889
Análise teórico-experimental do módulo dinâmico de compósitos asfálticos com argila calcinada
Soil biochemistry and microbial activity in vineyards under conventional and organic management at Northeast Brazil.
The São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the fact that orgThe São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the fact that organic fertilization can improve soil quality, we compared the effects of conventional and organic soil management on microbial activity and mycorrhization of seedless grape crops. We measured glomerospores number, most probable number (MPN) of propagules, richness of arbuscular mycorrhizal fungi (AMF) species, AMF root colonization, EE-BRSP production, carbon microbial biomass (C-MB), microbial respiration, fluorescein diacetate hydrolytic activity (FDA) and metabolic coefficient (qCO2). The organic management led to an increase in all variables with the exception of EE-BRSP and qCO2. Mycorrhizal colonization increased from 4.7% in conventional crops to 15.9% in organic crops. Spore number ranged from 4.1 to 12.4 per 50 g-1 soil in both management systems. The most probable number of AMF propagules increased from 79 cm-3 soil in the conventional system to 110 cm-3 soil in the organic system. Microbial carbon, CO2 emission, and FDA activity were increased by 100 to 200% in the organic crop. Thirteen species of AMF were identified, the majority in the organic cultivation system. Acaulospora excavata, Entrophospora infrequens, Glomus sp.3 and Scutellospora sp. were found only in the organically managed crop. S. gregaria was found only in the conventional crop. Organically managed vineyards increased mycorrhization and general soil microbial activity
The seesaw mechanism at TeV scale in the 3-3-1 model with right-handed neutrinos
We implement the seesaw mechanism in the 3-3-1 model with right-handed
neutrinos. This is accomplished by the introduction of a scalar sextet into the
model and the spontaneous violation of the lepton number. We identify the
Majoron as a singlet under symmetry, which makes it
safe under the current bounds imposed by electroweak data. The main result of
this work is that the seesaw mechanism works already at TeV scale with the
outcome that the right-handed neutrino masses lie in the electroweak scale, in
the range from MeV to tens of GeV. This window provides a great opportunity to
test their appearance at current detectors, though when we contrast our results
with some previous analysis concerning detection sensitivity at LHC, we
conclude that further work is needed in order to validate this search.Comment: about 13 pages, no figure
Resposta do tecido subcutâneo de camundongos à implantação de um novo biovidro à base de óxido de nióbio
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