RSMA for Dual-Polarized Massive MIMO Networks: A SIC-Free Approach

Aiming at overcoming practical issues of successive interference cancellation (SIC), this paper proposes a dual-polarized rate-splitting multiple access (RSMA) technique for a downlink massive multiple-input multiple-output (MIMO) network. By modeling the effects of polarization interference, an in-depth theoretical analysis is carried out, in which we derive tight closed-form approximations for the outage probabilities and ergodic sum-rates. Simulation results validate the accuracy of the theoretical analysis and confirm the effectiveness of the proposed approach. For instance, under low to moderate cross-polar interference, our results show that the proposed dual-polarized MIMO-RSMA strategy outperforms the single-polarized MIMO-RSMA counterpart for all considered levels of residual SIC error.Comment: arXiv admin note: substantial text overlap with arXiv:2211.0085

Microbial quality of soil from the Pampa biome in response to different grazing pressures

The aim of this study was to evaluate the impact of different grazing pressures on the activity and diversity of soil bacteria. We performed a long-term experiment in Eldorado do Sul, southern Brazil, that assessed three levels of grazing pressure: high pressure (HP), with 4% herbage allowance (HA), moderate pressure (MP), with 12% HA, and low pressure (LP), with 16% HA. Two reference areas were also assessed, one of never-grazed native vegetation (NG) and another of regenerated vegetation after two years of grazing (RG). Soil samples were evaluated for microbial biomass and enzymatic ( -glucosidase, arylsulfatase and urease) activities. The structure of the bacterial community and the population of diazotrophic bacteria were evaluated by RFLP of the 16S rRNA and nifH genes, respectively. The diversity of diazotrophic bacteria was assessed by partial sequencing of the 16S rDNA gene. The presence of grazing animals increased soil microbial biomass in MP and HP. The structures of the bacterial community and the populations of diazotrophic bacteria were altered by the different grazing managements, with a greater diversity of diazotrophic bacteria in the LP treatment. Based on the characteristics evaluated, the MP treatment was the most appropriate for animal production and conservation of the Pampa biome

Dual-Polarized Massive MIMO-RSMA Networks: Tackling Imperfect SIC

The polarization domain provides an extra degree of freedom (DoF) for improving the performance of multiple-input multiple-output (MIMO) systems. This paper takes advantage of this additional DoF to alleviate practical issues of successive interference cancellation (SIC) in rate-splitting multiple access (RSMA) schemes. Specifically, we propose three dual-polarized downlink transmission approaches for a massive MIMO-RSMA network under the effects of polarization interference and residual errors of imperfect SIC. The first approach implements polarization multiplexing for transmitting the users' data messages, which removes the need to execute SIC in the reception. The second approach transmits replicas of users' messages in the two polarizations, which enables users to exploit diversity through the polarization domain. The third approach, in its turn, employs the original SIC-based RSMA technique per polarization, and this allows the BS to transmit two independent superimposed data streams simultaneously. An in-depth theoretical analysis is carried out, in which we derive tight closed-form approximations for the outage probabilities of the three proposed approaches. Accurate approximations for the ergodic sum-rates of the two first schemes are also derived. Simulation results validate the theoretical analysis and confirm the effectiveness of the proposed schemes. For instance, under low to moderate cross-polar interference, the results show that, even under high levels of residual SIC error, our dual-polarized MIMO-RSMA strategies outperform the conventional single-polarized MIMO-RSMA counterpart. It is also shown that the performance of all RSMA schemes is impressively higher than that of single and dual-polarized massive MIMO systems employing non-orthogonal multiple access (NOMA) and orthogonal multiple access (OMA) techniques

Design of innovative clothing for pressure injury prevention: end-user evaluation in a mixed-methods study

The global relevance of pressure injury (PI) prevention technologies arise from their impact on the quality of life of people with limited mobility and the costs associated with treating these preventable injuries. The purpose of this mixed methods study is to evaluate the design of a prototype integrating Smart Health Textiles for PI prevention based on feedback from specialist nurses who care for individuals who are prone to or have PIs. This is a mixed methods study. A structured questionnaire was conducted as part of an evaluation of a prototype garment for the prevention of PIs. This questionnaire was applied during the evaluation of the prototype and afterwards focus group discussions were held with experts. Descriptive statistics techniques were used to analyze the data and thematic and integrated content analysis was conducted through concomitant triangulation. Nineteen nurses took part, aged 30 to 39 years (52.6%) and with 12.31 ± 8.96 years of experience. Participants showed that the prototype required more manipulation and physical effort, which interfered its usefulness, in addition to presenting difficulties with the openings and the material of the closure system, which interfered with the ease of use and learning. Overall satisfaction with the product was moderate, with some areas for improvement found, such as satisfaction, recommendations to colleagues, and pleasantness of use. It is concluded that areas for improvement have been found in all dimensions, including in the design of openings and the choice of materials. These findings supply significant insights for improving clothing to meet the needs of healthcare professionals and patients.The 4NoPressure project was co-financed by the Operational Program for Competitiveness and Internationalization (COMPETE 2020) under the PORTUGAL 2020 Partnership Agreement, with support from the European Regional Development Fund (ERDF), reference number POCI-01-0247- FEDER-039869

Characterization of the Gamboa virus serogroup (Orthobunyavirus genus, Peribunyaviridae family)

Comprehensive comparative phylogenetic analyses were performed on 17 Gamboa serogroup viruses (GAMSVs) from distinct geographic regions in the Americas and other representative members of the genus Orthobunyavirus (Peribunyaviridae), based on small (S), medium (M), and large (L) open reading frame full-length and partial sequences. Genome characterization showed that the GAMSVs divide into four clades or genotypes. The GAMSVs have a genetic organization similar to other orthobunyaviruses, except that they have a larger NSm protein than other orthobunyaviruses. A serosurvey for Gamboa virus antibodies was performed in plasma from birds, other wild animals, and humans living around the Tucuruí hydroelectric dam in Pará state, northern Brazil, a known focus of GAMSV activity. Newborn chicks (Gallus gallus domesticus) were experimentally infected with a GAMSV, and the pathogenesis is described. Histopathological changes were primarily in the lungs and liver. Also, a review of the ecology of the GAMSVs in the Americas is included. In sum, this study presents the genomic and evolutionary characterization of the Gamboa group and the potential model of pathogenesis, which would be helpful for diagnostic purposes, epidemiology, and immunopathogenesis studies

Serologic Survey of Hantavirus Infection, Brazilian Amazon

Federal University of Maranhão. São Luís, MA, Brazil.Federal University of Maranhão. São Luís, MA, Brazil.Federal University of Maranhão. São Luís, MA, Brazil.Federal University of Maranhão. São Luís, MA, Brazil.Federal University of Maranhão. São Luís, MA, Brazil.Federal University of Maranhão. São Luís, MA, Brazil.State Department of Health. São Luís, MA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil

Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase

AbstractBackground: Schistosomiasis is one of the world's major public health problems, and praziquantel (PZQ) is the only available drug to treat this neglected disease with an urgent demand for new drugs. Recent studies indicated that extracts from Piper aduncum L. (Piperaceae) are active against adult worms of Schistosoma mansoni, the major etiological agent of human schistosomiasis.Purpose: We investigated the in vitro schistosomicidal activity of cardamonin, a chalcone isolated from the crude extract of P. aduncum. Also, this present work describes, for the first time, the S. mansoni ATP diphosphohydrolase inhibitory activity of cardamonin, as well as, its molecular docking with S. mansoni ATPDase1, in order to investigate its mode of inhibition.Methods: In vitro schistosomicidal assays and confocal laser scanning microscopy were used to evaluate the effects of cardamonin on adult schistosomes. Cell viability was measured by MTT assay, and the S. mansoni ATPase activity was determined spectrophotometrically. Identification of the cardamonin binding site and its interactions on S. mansoni ATPDase1 were made by molecular docking experiments.Results: A bioguided fractionation of the crude extract of P. aduncum was carried out, leading to identification of cardamonin as the active compound, along with pinocembrin and uvangoletin. Cardamonin (25, 50, and 100 µM) caused 100% mortality, tegumental alterations, and reduction of oviposition and motor activity of all adult worms of S. mansoni, without affecting mammalian cells. Confocal laser scanning microscopy showed tegumental morphological alterations and changes on the numbers of tubercles of S. mansoni worms in a dose-dependent manner. Cardamonin also inhibited S. mansoni ATP diphosphohydrolase (IC50 of 23.54 µM). Molecular docking studies revealed that cardamonin interacts with the Nucleotide-Binding of SmATPDase 1. The nature of SmATPDase 1–cardamonin interactions is mainly hydrophobic and hydrogen bonding.Conclusion: This report provides evidence for the in vitro schistosomicidal activity of cardamonin and demonstrated, for the first time, that this chalcone is highly effective in inhibiting S. mansoni ATP diphosphohydrolase, opening the route to further studies of chalcones as prototypes for new S. mansoni ATP diphosphohydrolase inhibitors

Human Hantavirus Infection, Brazilian Amazon

Tropical Medicine Foundation of Amazonas. Manaus, AM, Brasil / Amazonas State University. Manaus, AM, Brasil / Nilton Lins University Center. Manaus, AM, Brasil.Tropical Medicine Foundation of Amazonas. Manaus, AM, Brasil / Amazonas State University. Manaus, AM, Brasil / Nilton Lins University Center. Manaus, AM, Brasil / University of Brasília. Brasília, DF, Brasil.Tropical Medicine Foundation of Amazonas. Manaus, AM, Brasil.Tropical Medicine Foundation of Amazonas. Manaus, AM, Brasil / Amazonas State University. Manaus, AM, Brasil / Nilton Lins University Center. Manaus, AM, Brasil.Health Surveillance Foundation. Manaus, AM, Brasil.Ministry of Health. Brasília, DF, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.Tropical Medicine Foundation of Amazonas. Manaus, AM, Brasil / Amazonas State University. Manaus, AM, Brasil / Nilton Lins University Center. Manaus, AM, Brasil / University of Brasília. Brasília, DF, Brasil

Culture-independent assessment of the diazotrophic Bradyrhizobium communities in the Pampa and Atlantic Forest Biomes localities in southern Brazil

The isolation of rhizobial strains from the root and stem nodules remains a commonly used method despite its limitations as it enables the identification of mainly dominant symbiotic groups within rhizobial communities. To overcome these limitations, we used genus-specific nifD primers in a cultureindependent assessment of Bradyrhizobium communities inhabiting soils in southern Brazil. The majority of nifD sequences were generated from DNA isolated from tropical-lowland pasture soils, although some soil samples originated from the Campos de Cima da Serra volcanic plateau. In the nifD tree, all the bradyrhizobial sequences comprised 38 clades, including 18 new clades. The sequences generated in this study were resolved into 22 clades and 21 singletons. The nifD bradyrhizobial assemblage contained Azorhizobium and a-proteobacterial methylotrophic genera, suggesting that these genera may have acquired their nif loci from Bradyrhizobium donors. The most common in the lowland pasture soils subclade III.3D branch comprises the isolates of mainly an American origin. On the other hand, subclade III.4, which was earlier detected in Brazil among Bradyrhizobium isolates nodulating native lupins, appears more common in the Campos de Cima da Serra soils. The second-largest group, Clade XXXVIII, has not yet been reported in culture-dependent studies, while another common group called Clade I represents a symbiovar predominating in Australia. The identification of the diverse nifD Clade I haplotypes in the tropical-lowland pastures infested by Australian Acacia spp implies that the introduction of these legumes to southern Brazil has resulted in the dissemination of their bradyrhizobial symbionts.This work was supported by a grant UMO-2014/15/B/ NZ8/00259 (TS-JB) from The National Science Centre (NCN) and a grant from CAPES/FAPERGS Public Notice 12/2013.http://www.elsevier.com/locate/syapmdm2022BiochemistryGeneticsMicrobiology and Plant Patholog