6,143 research outputs found
Label-free detection of anticancer drug paclitaxel in living cells by confocal Raman microscopy
Confocal Raman microscopy, a non-invasive, label-free, and high spatial resolution imaging technique is employed to trace the anticancer drug paclitaxel in living Michigan Cancer Foundation-7 (MCF-7) cells. The Raman images were treated by K-mean cluster analysis to detect the drug in cells. Distribution of paclitaxel in cells is verified by calculating the correlation coefficient between the reference spectrum of the drug and the whole Raman image spectra. A time dependent gradual diffusion of paclitaxel all over the cell is observed suggesting a complementary picture of the pharmaceutical action of this drug based on rapid binding of free tubulin to crystallized paclitaxel. (C) 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4794871
Consequences of anisotropy in electrical charge storage: application to the characterization by the mirror method of TiO2 rutile
This article is devoted first to anisotropic distributions of stored electric
charges in isotropic materials, second to charge trapping and induced
electrostatic potential in anisotropic dielectrics. On the one hand, we examine
the case of anisotropic trapped charge distributions in linear homogeneous
isotropic (LHI) insulators, obtained after an electron irradiation in a
scanning electron microscope. This injection leads to the formation of a mirror
image
Octet Magnetic Moments with Null Instantons and Semibosonized Nambu-Jona-Lasinio Model
It is shown that the difference between the magnetic moment results in the
quark model with null instantons and semibosonized Nambu-Jona-Lasinio model
lies in the description of the magnetic moment of the -hyperon.Comment: RevTex, 6 pages, submitted to Progr.Theor.Phy
Deformation of grain boundaries in polar ice
The ice microstructure (grain boundaries) is a key feature used to study ice
evolution and to investigate past climatic changes. We studied a deep ice core,
in Dome Concordia, Antarctica, which records past mechanical deformations. We
measured a "texture tensor" which characterizes the pattern geometry and
reveals local heterogeneities of deformation along the core. These results
question key assumptions of the current models used for dating
Extragalactic database. VII Reduction of astrophysical parameters
The Lyon-Meudon Extragalactic database (LEDA) gives a free access to the main
astrophysical parameters for more than 100,000 galaxies. The most common names
are compiled allowing users to recover quickly any galaxy. All these measured
astrophysical parameters are first reduced to a common system according to well
defined reduction formulae leading to mean homogeneized parameters. Further,
these parameters are also transformed into corrected parameters from widely
accepted models. For instance, raw 21-cm line widths are transformed into mean
standard widths after correction for instrumental effect and then into maximum
velocity rotation properly corrected for inclination and non-circular velocity.
This paper presents the reduction formulae for each parameter: coordinates,
morphological type and luminosity class, diameter and axis ratio, apparent
magnitude (UBV, IR, HI) and colors, maximum velocity rotation and central
velocity dispersion, radial velocity, mean surface brightness, distance modulus
and absolute magnitude, and group membership. For each of these parameters
intermediate quantities are given: galactic extinction, inclination,
K-correction etc..
All these parameters are available from direct connexion to LEDA (telnet
lmc.univ-lyon1.fr, login: leda, no passwd
OR http://www-obs.univ-lyon1.fr/leda ) and distributed on a standard CD-ROM
(PGC-ROM 1996) by the Observatoire de Lyon via the CNRS (mail to
[email protected]).Comment: 13 pages, 12 figures. The CDROM of the extragalactic database LEDA is
available by mailing to: [email protected]
A Simple n-Dimensional Intrinsically Universal Quantum Cellular Automaton
We describe a simple n-dimensional quantum cellular automaton (QCA) capable
of simulating all others, in that the initial configuration and the forward
evolution of any n-dimensional QCA can be encoded within the initial
configuration of the intrinsically universal QCA. Several steps of the
intrinsically universal QCA then correspond to one step of the simulated QCA.
The simulation preserves the topology in the sense that each cell of the
simulated QCA is encoded as a group of adjacent cells in the universal QCA.Comment: 13 pages, 7 figures. In Proceedings of the 4th International
Conference on Language and Automata Theory and Applications (LATA 2010),
Lecture Notes in Computer Science (LNCS). Journal version: arXiv:0907.382
Effective field theory and the quark model
We analyze the connections between the quark model (QM) and the description
of hadrons in the low-momentum limit of heavy-baryon effective field theory in
QCD. By using a three-flavor-index representation for the effective baryon
fields, we show that the ``nonrelativistic'' constituent QM for baryon masses
and moments is completely equivalent through O(m_s) to a parametrization of the
relativistic field theory in a general spin--flavor basis. The flavor and spin
variables can be identified with those of effective valence quarks. Conversely,
the spin-flavor description clarifies the structure and dynamical
interpretation of the chiral expansion in effective field theory, and provides
a direct connection between the field theory and the semirelativistic models
for hadrons used in successful dynamical calculations. This allows dynamical
information to be incorporated directly into the chiral expansion. We find, for
example, that the striking success of the additive QM for baryon magnetic
moments is a consequence of the relative smallness of the non-additive
spin-dependent corrections.Comment: 25 pages, revtex, no figure
The Goldstone boson equivalence theorem with fermions
The calculation of the leading electroweak corrections to physical transition
matrix elements in powers of can be greatly simplified in the limit
through the use of the Goldstone boson equivalence
theorem. This theorem allows the vector bosons and to be replaced
by the associated scalar Goldstone bosons , which appear in the
symmetry breaking sector of the Standard Model in the limit of vanishing gauge
couplings. In the present paper, we extend the equivalence theorem
systematically to include the Yukawa interactions between the fermions and the
Higgs and Goldstone bosons of the Standard Model. The corresponding Lagrangian
is given, and is formally renormalized to all orders. The
renormalization conditions are formulated both to make connection with physical
observables and to satisfy the requirements underlying the equivalence theorem.
As an application of this framework, we calculate the dominant radiative
corrections to fermionic Higgs decays at one loop including the virtual effects
of a heavy top quark. We apply the result to the decays
and , and find that the equivalence theorem results
including fermions are quite accurate numerically for Higgs-boson masses GeV, respectively, even for GeV.Comment: 32 pages, uses LaTeX2e, epsf and rotate, 7 figures included as
separate uuencoded packed file. A complete PostScript version can also be
obtained from
http://www.physik.tu-muenchen.de/tumphy/d/T30d/PAPERS/TUM-HEP-227-95.ps.g
Surface induced selective delamination of amphiphilic ABA block copolymer thin films
This is the result of an ongoing collaboration with Dr. N. Sommerdijk’s Biomaterials group at the University of Eindhoven (the Netherlands) and illustrates the close collaboration that exists in pursuing the design and application of novel polymeric materials between the two groups. This details work on a physical phenomenon (selective delamination) and key materials (amphiphilic block copolymers) that have subsequently been applied in the design of novel biomaterials. These results have appeared in a larger body of work including Advanced Materials, Angewandtie Chemie International Edition and the Journal of Materials Chemistry
Acute stress affects peripersonal space representation in cortisol stress responders.
Peripersonal space is the representation of the space near the body. It is implemented by a dedicated multisensory-motor network, whose purpose is to predict and plan interactions with the environment, and which can vary depending on environmental circumstances. Here, we investigated the effect on the PPS representation of an experimentally induced stress response and compared it to a control, non-stressful, manipulation. We assessed PPS representation in healthy humans, before and after a stressful manipulation, by quantifying visuotactile interactions as a function of the distance from the body, while monitoring salivary cortisol concentration. While PPS representation was not significantly different between the control and experimental group, a relation between cortisol response and changes in PPS emerged within the experimental group. Participants who showed a cortisol stress response presented enhanced visuotactile integration for stimuli close to the body and reduced for far stimuli. Conversely, individuals with a less pronounced cortisol response showed a reduced difference in visuotactile integration between the near and the far space. In our interpretation, physiological stress resulted in a freezing-like response, where multisensory-motor resources are allocated only to the area immediately surrounding the body
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