1,524 research outputs found

    Chemistry. Meteorology, and Geology

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    S15RS SGFB No. 10 (Union Seating)

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    A FINANCE BILL To allocate a maximum of seven thousand seven hundred fifty-seven dollars and ninety-three cents ($7,757.93) from the Student Government Senate General Contingency Account to fund nine new round tables and thirty new chairs for the LSU Student Union

    Mos is not required for the initiation of meiotic maturation in Xenopus oocytes

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    The Effect of Common-Mode Voltage Elimination on the Iron Loss in Machine Core Laminations of Multilevel Drives

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    This paper studies the effect of common-mode voltage elimination (CMVE) on the iron loss of electrical machine core laminations under multilevel converter supply. Three identical magnetic ring cores are excited by either a three-level converter or a five-level voltage source converter to study the behavior of CMVE on a three-phase system. Both multilevel converters are controlled by using a space vector pulse width modulation as it is one of the most often used techniques for CMVE. These experimental results are confirmed numerically with a dynamic iron loss model. In addition, the effect of CMVE, at different switching frequencies, on the core loss of a synchronous machine is numerically studied. The results presented in this paper show that the core loss is considerably increased when the CMVE is implemented. However this iron loss increase in five-level drive systems is lower compared to the three-level ones. Therefore, it is important that the designers of drive systems take such effects into consideration.Peer reviewe

    Effect of Multilevel Inverter Supply on Core Losses in Magnetic Materials and Electrical Machines

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    The effect of multilevel inverter supply on power losses in magnetic cores and electrical machines is studied. A dynamic numerical model for the hysteresis, eddy current, and excess losses in a core lamination is first developed. By both measurements and simulations for a ring-core inductor, we demonstrate how increasing the number of inverter voltage levels decreases the iron losses when compared with traditional two-level supply. Although the switching frequency has a significant impact on the iron losses in the case of a traditional two-level inverter, using three or five voltage levels makes the losses almost independent of the switching. Finally, finite-element simulations show that simi-lar reductions are also possible for the core losses of 150-kVA and 12.5-MW wound-field synchronous machines, in which rather low switching frequencies are typically used. Calorimetric loss measurements are also presented for the 150-kVA machine in order to confirm the significant effect of switching frequency on the core losses with two-level inverter supply.Peer reviewe

    Symmetries of Electrostatic Interaction between DNA Molecules

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    We study a model for pair interaction UU of DNA molecules generated by the discrete dipole moments of base-pairs and the charges of phosphate groups, and find noncommutative group of eighth order S{\cal S} of symmetries that leave UU invariant. We classify the minima using group S{\cal S} and employ numerical methods for finding them. The minima may correspond to several cholesteric phases, as well as phases formed by cross-like conformations of molecules at an angle close to 90o\rm{90}^{o}, "snowflake phase". The results depend on the effective charge QQ of the phosphate group which can be modified by the polycations or the ions of metals. The snowflake phase could exist for QQ above the threshold QCQ_C. Below QCQ_C there could be several cholesteric phases. Close to QCQ_C the snowflake phase could change into the cholesteric one at constant distance between adjacent molecules.Comment: 13 pages, 4 figure

    A twist in chiral interaction between biological helices

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    Using an exact solution for the pair interaction potential, we show that long, rigid, chiral molecules with helical surface charge patterns have a preferential interaxial angle ~((RH)^1/2)/L, where L is the length of the molecules, R is the closest distance between their axes, and H is the helical pitch. Estimates based on this formula suggest a solution for the puzzle of small interaxial angles in a-helix bundles and in cholesteric phases of DNA.Comment: 7 pages, 2 figures, PDF file onl

    Npas4 is activated by melatonin, and drives the clock gene Cry1 in the ovine pars tuberalis

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    Seasonal mammalsintegrate changes in the duration of nocturnal melatonin secretion to drive annual physiologic cycles. Melatonin receptors within the proximal pituitary region, the pars tuberalis (PT), are essential in regulating seasonal neuroendocrine responses. In the ovine PT, melatonin is known to influence acute changes in transcriptional dynamics coupled to the onset (dusk) and offset (dawn) of melatonin secretion, leading to a potential interval-timing mechanism capable of decoding changes in day length (photoperiod). Melatonin offset at dawn is linked to cAMP accumulation, which directly induces transcription of the clock gene Per1. The rise of melatonin at dusk induces a separate and distinct cohort, including the clock-regulated genes Cry1 and Nampt, but little is known of the upstream mechanisms involved. Here, we used next-generation sequencing of the ovine PT transcriptome at melatonin onset and identified Npas4 as a rapidly induced basic helix-loop-helix Per-Arnt-Sim domain transcription factor. In vivo we show nuclear localization of NPAS4 protein in presumptive melatonin target cells of the PT (α-glycoprotein hormone-expressing cells), whereas in situ hybridization studies identified acute and transient expression in the PT of Npas4 in response to melatonin. In vitro, NPAS4 forms functional dimers with basic helix loop helix-PAS domain cofactors aryl hydrocarbon receptor nuclear translocator (ARNT), ARNT2, and ARNTL, transactivating both Cry1 and Nampt ovine promoter reporters. Using a combination of 5'-deletions and site-directed mutagenesis, we show NPAS4-ARNT transactivation to be codependent upon two conserved central midline elements within the Cry1 promoter. Our data thus reveal NPAS4 as a candidate immediate early-response gene in the ovine PT, driving molecular responses to melatonin
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