Experiences after the diagnosis of chronic renal failure from the perspective of patients / Vivências após o diagnóstico da insuficiência renal crônica sob a ótica dos pacientes

Objective: to analyze the experiences of the diagnosis of Chronic Kidney Disease from the perspective of patients. Method: qualitative study conducted through semi-structured interviews conducted with patients treated in a hemodialysis service; the data were submitted to Bardin's Content analysis. Results: the experiences were organized into the following significant categories: Feelings experienced at the time of diagnosis; Impacts of diagnosis; Denial of the disease; The paradox of gratitude and Coping with the disease. Final considerations: the experience of the diagnosis of Chronic Kidney Disease acquires a unique perspective for each patient subsidized by subjective aspects, by the care and family support to which he has access.Objetivo: analizar las experiencias de diagnóstico de la Enfermedad Renal Crónica desde la perspectiva de los pacientes. Método: estudio cualitativo realizado a través de entrevistas semiestructuradas realizadas con pacientes tratados en un servicio de hemodiálisis; los datos fueron enviados al Análisis de Contenido de Bardin. Resultados: las experiencias fueron organizadas en las siguientes categorías significativas: Sentimientos experimentados en el momento del diagnóstico; Impactos del diagnóstico; Negación de la enfermedad; La paradoja de la gratitud y Enfrentamiento de la enfermedad. Consideraciones finales: la experiencia del diagnóstico de Enfermedad Renal Crónica adquiere una perspectiva única para cada paciente subsidiada por aspectos subjetivos, por el cuidado y apoyo familiar al que tiene acceso.Objetivo: analisar as vivências do diagnóstico de Doença Renal Crônica sob a ótica dos pacientes. Método: estudo qualitativo realizado por meio de entrevistas semiestruturadas realizadas junto aos pacientes atendidos em um serviço de hemodiálise; os dados foram submetidos à análise de Conteúdo de Bardin. Resultados: as vivências foram organizadas nas seguintes categorias significativas: Sentimentos vivenciados no momento do diagnóstico; Impactos do diagnóstico; Negação da doença; O paradoxo da gratidão e Enfrentamento da doença. Considerações finais: a vivência do diagnóstico da Doença Renal Crônica adquire uma perspectiva singular para cada paciente subsidiada por aspectos de ordem subjetiva, pelo suporte assistencial e familiar ao qual ele tem acesso.

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

Association of child maltreatment with South African adults’ wages:Evidence from the Cape area panel study

Child maltreatment is a prevalent public health problem in both developed and developing countries. While many studies have investigated the relationship between violence against children and health of the victims, little is known about the long term economic consequences of child maltreatment, especially in developing countries. Using data from the Cape Area Panel Study, this paper applies Heckman selection models to investigate the relationship between childhood maltreatment and young adults’ wages in South Africa. The results show that, on average, any experience of physical or emotional abuse during childhood is associated with a later 12% loss of young adults’ wages. In addition, the correlation between physical abuse and economic consequence (14%) is more significant than the relationship between emotional abuse and wages (8%) of young adults; and the higher the frequency of maltreatment, the greater the associations with wages. With respect to gender differences, wage loss due to the experience of childhood maltreatment is larger for females than males. Specifically, males’ wages are more sensitive to childhood emotional abuse, while females’ wages are more likely to be affected by childhood physical abuse. These results emphasize the importance of prioritizing investments in prevention and intervention programs to reduce the prevalence of child maltreatment and to help victims better overcome the long-term negative effect

High gamma oscillations in medial temporal lobe during overt production of speech and gestures

The study of the production of co-speech gestures (CSGs), i.e., meaningful hand movements that often accompany speech during everyday discourse, provides an important opportunity to investigate the integration of language, action, and memory because of the semantic overlap between gesture movements and speech content. Behavioral studies of CSGs and speech suggest that they have a common base in memory and predict that overt production of both speech and CSGs would be preceded by neural activity related to memory processes. However, to date the neural correlates and timing of CSG production are still largely unknown. In the current study, we addressed these questions with magnetoencephalography and a semantic association paradigm in which participants overtly produced speech or gesture responses that were either meaningfully related to a stimulus or not. Using spectral and beamforming analyses to investigate the neural activity preceding the responses, we found a desynchronization in the beta band (15-25 Hz), which originated 900 ms prior to the onset of speech and was localized to motor and somatosensory regions in the cortex and cerebellum, as well as right inferior frontal gyrus. Beta desynchronization is often seen as an indicator of motor processing and thus reflects motor activity related to the hand movements that gestures add to speech. Furthermore, our results show oscillations in the high gamma band (50-90 Hz), which originated 400 ms prior to speech onset and were localized to the left medial temporal lobe. High gamma oscillations have previously been found to be involved in memory processes and we thus interpret them to be related to contextual association of semantic information in memory. The results of our study show that high gamma oscillations in medial temporal cortex play an important role in the binding of information in human memory during speech and CSG production