2,395 research outputs found
Abuses and Distortions in Emotional Processes as Risk Factors for Parricide
Parricide is a rare case of murder having a strong emotional impact on public opinion, especially when it is heinous and perpetrated by minors. Based on the analysis of the judicial files archived at the Minor Penal Institute "N. Fornelli" of Bari, the authors will report three impressive cases perpetrated by minors, by focusing on their emotional features. Differences between the crimes of parricide committed by adults and minors will be highlighted, by analyzing the peculiar relations between the problems underlying parricide and the role played by abuses and maltreatments experienced by minors perpetrating such crime. In particular, attention will be paid to the emotional processes aroused in minor parricide offenders
Digital interaction: where are we going?
In the framework of the AVI 2018 Conference, the interuniversity center ECONA has organized a thematic workshop on "Digital Interaction: where are we going?". Six contributions from the ECONA members investigate different perspectives around this thematic
Edition Visualization Technology: A Simple Tool to Visualize TEI-based Digital Editions
The TEI schemas and guidelines have made it possible for many scholars and researchers to encode texts of any kind for (almost) all kinds of purposes, but this excellent standard is matched by an astounding diversity of publishing tools, which is particularly true when it comes to image-based digital editions. The different needs of scholars, coupled with the constant search for an effective price/result ratio and the local availability of technical skills, have led to a remarkable fragmentation: publishing solutions range from simple HTML pages produced using the TEI stylesheets (or the TEI Boilerplate software) to very complex frameworks based on CMS and SQL search engines. Researchers of the Digital Vercelli Book project started looking into a simple, user-friendly solution and eventually decided to build their own: EVT (Edition Visualization Technology) has been under development since about 2010 and has turned into a flexible tool that can be used to create a web-based digital edition starting from transcription files encoded in TEI XML. This paper describes why this tool was created, how it works, and developments planned for the future
RET/PTC3 translocation in a rare hemorrhagic brain metastasis of papillary thyroid cancer post Chernobyl radiation affects vessels ultrastructure
Abstract
Background
Slow progression and good prognosis are the usual characteristics of papillary thyroid carcinoma (PTC). The presence of brain metastases (0.4–1.2%) is suggestive of a worse prognosis. RET/PTC rearrangements were particularly prevalent in PTCs developed after Chernobyl nuclear accident.
Case description
A 50-year-old woman born in Slovakia, exposed to radiation resulting from the accident at the Chernobyl nuclear power plant, affected since 2017 by papillary thyroid cancer and in therapy at our hospital, experimented cerebral hemorrhagic metastasis. Biopsy analyses revealed a RET/PTC3 rearrangement, so our aim was to find possible morphological relation between hemorrhagic metastasis and RET/PTC3 translocation.
Results
Immunohistochemical analysis showed diffuse and intense positivity for VEGF in endothelial cells of the neoplasm’ vascular network. Transmission electron microscopy images showed vessels with unorganized pattern and uneven diameters. In particular, metastasis endothelial cells (MECs) showed irregular shape and size, thickened cytoplasm and swelling of endoplasmic reticulum. MECs organized in irregular monolayers or multiple layers, surrounded by a thickened but unstructured extracellular matrix. Absence of strong junctional complexes among MECs resulted in a further weakened vessels wall.
Conclusion
RET/PTC3 translocation causes VEGF overexpression via STAT3 signaling cascade and the increased amount of VEGF adds to the greater amount of VEGFRs expressed by MECs. Our ultrastructural investigation show that this condition creates a massive growth of altered vessels prone to bleeding. The clinical significance of our study consists in alert oncologist and surgeons on possible arising of hemorrhagic brain metastases in patients with PTC and RET/PTC3 translocation exposed to ionizing radiation as people living in areas caught up in Chernobyl or Fukushima disasters
Моделирование магнетронной распылительной системы методом конечных элементов
В работе проведено моделирование магнетронной распылительной системы методом конечных элементов и методом Галеркина. Получены распределения концентрации и скоростей носителей заряда, распределение электрического потенциала и магнитного поля, рассмотрены временные зависимости физических величин. Разработано программное обеспечение для моделирования сложных физических задач. Проведена верификация расчетного алгоритма на примере решения модельных задач. Отличительной особенностью исследуемой модели от существующих является учет нестационарного и конвективного слагаемых в уравнении для переноса скорости электрона и максимально точная реализация всех слагаемых в дифференциальном уравнении (в рамках метода Галеркина).The dissertation examines the modeling of a magnetron sputtering system by finite element analysis and Galerkin method. The model makes it possible to calculate the concentration, velocity, temperature, electrical potential and magnetic field. The methods and the code developed according to the model are usable for modeling complex physical tasks. The work also includes analysis and verification of results
Flat band separation and robust spin-Berry curvature in bilayer kagome metals
Kagome materials have emerged as a setting for emergent electronic phenomena
that encompass different aspects of symmetry and topology. It is debated
whether the XVSn kagome family (where X is a rare earth element), a
recently discovered family of bilayer kagome metals, hosts a topologically
non-trivial ground state resulting from the opening of spin-orbit coupling
gaps. These states would carry a finite spin-Berry curvature, and topological
surface states. Here, we investigate the spin and electronic structure of the
XVSn kagome family. We obtain evidence for a finite spin-Berry
curvature contribution at the center of the Brillouin zone, where the nearly
flat band detaches from the dispersing Dirac band because of spin-orbit
coupling. In addition, the spin-Berry curvature is further investigated in the
charge density wave regime of ScVSn, and it is found to be robust
against the onset of the temperature-driven ordered phase. Utilizing the
sensitivity of angle resolved photoemission spectroscopy to the spin and
orbital angular momentum, our work unveils the spin-Berry curvature of
topological kagome metals, and helps to define its spectroscopic fingerprint.Comment: 21 pages, 4 figure
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