Exact Bosonic and Supersymmetric String Black Hole Solutions

We show that Witten's two-dimensional string black hole metric is exactly conformally invariant in the supersymmetric case. We also demonstrate that this metric, together with a recently proposed exact metric for the bosonic case, are respectively consistent with the supersymmetric and bosonic $\sigma$-model conformal invariance conditions up to four-loop order.Comment: 14

The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea.

PurposeDiarrhea is recognized as a common adverse event associated with tyrosine kinase inhibitors (TKIs), with those targeting the ErbB family of receptors being associated with the highest rate of diarrhea.MethodsThis paper reviews data on the incidence, timing, and duration of diarrhea associated with US Food and Drug Administration-approved ErbB family-targeted TKIs from the published literature, and sets forth recommendations for management.ResultsIn the absence of anti-diarrheal prophylaxis the incidence of any-grade diarrhea varies and typically occurs early during the course of treatment. Although it is difficult to determine if the incidence and severity of diarrhea is related to inhibition of a particular kinase target because of the multi-targeted and overlapping activity of many agents, evidence suggests that second-generation TKIs with broader target profiles (i.e., afatinib, lapatinib, neratinib) result in a higher incidence of diarrhea compared with highly specific first- (erlotinib, gefitinib) or third- (osimertinib) generation agents. The mechanisms responsible for TKI-associated diarrhea are not fully understood and are likely multi-factorial, involving dysregulated ion transport, inflammation, and mucosal injury. Management strategies have been developed-and continue to be refined-to prevent and reduce the severity and duration of TKI-associated diarrhea. For agents associated with more significant symptoms, anti-diarrheal prophylaxis reduces the incidence and severity of diarrhea, and ongoing studies are evaluating specific strategies to further reduce incidence and duration of TKI-associated diarrhea.ConclusionsContinued investigations into risk factors and pharmacogenomic markers for diarrhea may further improve management of this common toxicity

Current oscillations in Vanadium Dioxide: evidence for electrically triggered percolation avalanches

In this work, we experimentally and theoretically explore voltage controlled oscillations occurring in micro-beams of vanadium dioxide. These oscillations are a result of the reversible insulator to metal phase transition in vanadium dioxide. Examining the structure of the observed oscillations in detail, we propose a modified percolative-avalanche model which allows for voltage-triggering. This model captures the periodicity and waveshape of the oscillations as well as several other key features. Importantly, our modeling shows that while temperature plays a critical role in the vanadium dioxide phase transition, electrically induced heating cannot act as the primary instigator of the oscillations in this configuration. This realization leads us to identify electric field as the most likely candidate for driving the phase transition

It Takes a Village: Understanding the Collective Security Efficacy of Employee Groups

An organization’s ability to successfully manage information security incidents is determined by the actions of its employees, as well as the actions of various groups of employees within its organizational boundaries. To date, information security research has primarily focused on individual-level phenomena and has not yet explored group-level phenomena such as how employee groups recognize and respond to security incidents in a way that is consistent with the organization’s security goals and objectives. The current study addresses this gap, thereby answering the research call for group-level security research perspectives. The present study explores how employee groups formulate their collective security efficacy, which influences how group members recognize and respond to information security incidents. Using a case study of a large healthcare research organization (HRO), we analyze two security incidents, a malware attack, and a physical security breach, to identify a unique set of ecological and social properties of employee groups that are salient to their collective security efficacy

Scheme invariants in φ^4 theory in four dimensions

We provide an analysis of the structure of renormalization scheme invariants for the case of ϕ4 theory, relevant in four dimensions. We give a complete discussion of the invariants, up to four loops, and include some partial results at five loops, showing that there are considerably more invariants than one might naively have expected. We also show that one-vertex reducible contributions may consistently be omitted in a well-defined class of schemes, which of course includes ¯¯¯¯¯¯MS

A COMPARISON OF PERSONAL SOCIAL MEDIA RISK PERCEPTIONS BETWEEN UNDERGRADUATE STUDENTS AND HUMAN RESOURCE PROFESSIONALS

This study contrasts the social media risk perceptions of undergraduate students, versus those of certified Human Resource professionals. Social media is widely used by most segments of the population, and particularly among the age group that includes most undergraduate students. Organizations hiring employees are increasingly examining job applicant\u27s social media postings as part of the applicant screening process. In this study we examine how these groups differ in their perceptions of the risks inherent in using social media, and what these differences may mean for students seeking employment. Recommendations are made for raising undergraduate student awareness of these risks

Social Media Risk Perceptions of Human Resource Professionals: Issues Undergraduate Students Should Consider

This study contrasts the social media risk perceptions of undergraduate students, versus those of certified Human Resource professionals. Social media is widely used by most segments of the population, and particularly among the age group that includes most undergraduate students. Organizations hiring employees are increasingly examining job applicant\u27s social media postings as part of the applicant screening process. In this study we examine how these groups differ in their perceptions of the risks inherent in using social media, and what these differences may mean for students seeking employment. Recommendations are made for raising undergraduate student awareness of these risks

Ultraviolet properties of noncommutative non-linear sigma-models in two dimensions

We discuss the ultra-violet properties of bosonic and supersymmetric noncommutative non-linear sigma-models in two dimensions, both with and without a Wess-Zumino-Witten term.Comment: 10 pages, including 1 figure. Plain TeX. Uses Harvmac and epsf. Minor revisions and additional reference. Version to be published in Phys. Lett.