La gestion des manoirs anglais de l’abbaye du Bec (fin du XIIIe - début du XIVe siècle)

Pour la connaissance de l’agriculture médiévale, les comptes manoriaux anglais, principalement ecclésiastiques, sont très largement utilisés. Précis, abondants, continus, ils offrent à l’historien une documentation tentante. Les rendements qu’on en tire exercent une influence prépondérante dans l’établissement des moyennes, sur l’évaluation de la productivité. La France n’ayant à peu près rien qui leur soit comparable, on lui étendrait facilement les résultats qu’ils expriment. La réputation ..

Extending Triazolyl-Based Release under Mildly Acidic Conditions To Give Aniline Derivatives

International audienceTriazolyl derivatives of anilines were prepared and evaluated as releasing systems at mildly acidic pH values. Two triazolyl derivatives showed convenient pH sensitivity, being stable at pH 7.3 and rapidly hydrolyzed at pH values below 5. A generalized mechanism is proposed from additional theoretical investigation

Foldamers of bifunctional diketopiperazines displaying a beta-bend ribbon structure

The synthesis of two oligomers, of a bifunctional diketopiperazine scaffold DKP-1, formally derived from the cyclization of l-aspartic acid and (S)-2,3-diaminopropionic acid, is reported. A trimeric and a tetrameric structure were prepared by solution-phase peptide synthesis (Boc strategy). Conformational analysis of these derivatives was carried out by a combination of 1H NMR spectroscopy, CD spectroscopy, and molecular modeling, and revealed the formation of \u3b2-bend ribbon involving 10-membered H-bonded rings and a reverse turn of the growing peptide chain

Foldamers of bifunctional diketopiperazines displaying a \uf062-bend ribbon structure.

The synthesis of two oligomers, of a bifunctional diketopiperazine scaffold DKP-1, formally derived from the cyclization of l-aspartic acid and (S)-2,3-diaminopropionic acid, is reported. A trimeric and a tetrameric structure were prepared by solution-phase peptide synthesis (Boc strategy). Conformational analysis of these derivatives was carried out by a combination of 1H NMR spectroscopy, CD spectroscopy, and molecular modeling, and revealed the formation of \u3b2-bend ribbon involving 10-membered H-bonded rings and a reverse turn of the growing peptide chain

Neodimium(III) Polyaminocarboxylate as Photostable Probe for Luminescence Imaging within the Biological Diagnostic Window

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Lanthanide-Based Polyaminocarboxylate Complexes as Photostable Probes for Luminescence Imaging within the Near-Infrared Biological Diagnostic Window

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Generation-3 polyamidoamine dendrimers functionalized with aza-bodipy chromophores for in vitroin\ vitro optical imaging within biological diagnostic window

International audienc

Dendrimers incorporating lanthanide cations as near-infrared imaging agents

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Development of triazolyl-based pH responsive releasing systems

International audienc